Protein kinase Cε activity induces anti-inflammatory and anti-apoptotic genes via an ERK1/2- and NF-κ B-dependent pathway to enhance vascular protection

Biochemical Journal

Volumn 447, Issue 2, 2012, Pages 193-204

  Dumont, Odile ^a   Mylroie, Hayley ^a   Bauer, Andrea ^a   Calay, Damien ^a   Sperone, Andrea ^a   Thornton, Clare ^a   Hamdulay, Shahir S ^a   Ali, Nadira ^a   Boyle, Joseph J ^a   Choo, Joan R ^a   Samarel, Allen M ^b   Haskard, Dorian O ^a   Randi, Anna M ^a   Evans, Paul C ^a   Mason, Justin C ^a  

^a NATIONAL HEART AND LUNG INSTITUTE   (United Kingdom)

^b LOYOLA UNIVERSITY CHICAGO   (United States)

Author keywords

Apoptosis; Cytoprotection; Endothelium; Inflammation; Protein kinase C (PKC)

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 3 (4 METHYLPHENYLSULFONYL) 2 PROPENENITRILE; ENDOTHELIAL CELL ANTIBODY; ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1; I KAPPA B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERCELLULAR ADHESION MOLECULE 1; MITOGEN ACTIVATED PROTEIN KINASE 1; PROTEIN KINASE C EPSILON; STRESS ACTIVATED PROTEIN KINASE; SYNAPTOTAGMIN I; TUMOR NECROSIS FACTOR ALPHA; VASCULAR CELL ADHESION MOLECULE 1;

ANIMAL CELL; ANTIINFLAMMATORY ACTIVITY; APOPTOSIS; ARTICLE; CELL PROTECTION; CONTROLLED STUDY; ENDOTHELIUM CELL; ENZYME ACTIVITY; GENE EXPRESSION; GENE INDUCTION; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; DNA-BINDING PROTEINS; ENZYME ACTIVATION; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; INTERCELLULAR ADHESION MOLECULE-1; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MAP KINASE KINASE 4; MAP KINASE SIGNALING SYSTEM; MICE; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; NF-KAPPA B; NUCLEAR PROTEINS; PROTEIN KINASE C-EPSILON; PROTO-ONCOGENE PROTEINS C-BCL-2; VASCULAR CELL ADHESION MOLECULE-1;

EID: 84866859673     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20120574     Document Type: Article

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