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Volumn 326, Issue 2, 2012, Pages 155-160

Targeting Jab1/CSN5 in nasopharyngeal carcinoma

Author keywords

DNA repair; Epstein Barr virus associated malignancy; Jab1 CSN5; Nasopharyngeal carcinoma; P27Kip1; Tumorigenesis

Indexed keywords

CISPLATIN; CONSTITUTIVE PHOTOMORPHOGENIC 9 SIGNALOSOME SUBUNIT 5 PROTEIN; ONCOPROTEIN; STAT3 PROTEIN; UNCLASSIFIED DRUG;

EID: 84866859568     PISSN: 03043835     EISSN: 18727980     Source Type: Journal    
DOI: 10.1016/j.canlet.2012.07.033     Document Type: Article
Times cited : (45)

References (70)
  • 1
    • 84857781938 scopus 로고    scopus 로고
    • Deciphering the molecular genetic basis of NPC through molecular, cytogenetic, and epigenetic approaches
    • Lo K.W., Chung G.T., To K.F. Deciphering the molecular genetic basis of NPC through molecular, cytogenetic, and epigenetic approaches. Semin. Cancer Biol. 2012, 22:79-86.
    • (2012) Semin. Cancer Biol. , vol.22 , pp. 79-86
    • Lo, K.W.1    Chung, G.T.2    To, K.F.3
  • 2
    • 2442540470 scopus 로고    scopus 로고
    • Focus on nasopharyngeal carcinoma
    • Lo K.W., To K.F., Huang D.P. Focus on nasopharyngeal carcinoma. Cancer Cell 2004, 5:423-428.
    • (2004) Cancer Cell , vol.5 , pp. 423-428
    • Lo, K.W.1    To, K.F.2    Huang, D.P.3
  • 4
    • 47549106723 scopus 로고    scopus 로고
    • Nasopharyngeal carcinoma - review of the molecular mechanisms of tumorigenesis
    • Chou J., Lin Y.C., Kim J., You L., Xu Z., He B., Jablons D.M. Nasopharyngeal carcinoma - review of the molecular mechanisms of tumorigenesis. Head Neck 2008, 30:946-963.
    • (2008) Head Neck , vol.30 , pp. 946-963
    • Chou, J.1    Lin, Y.C.2    Kim, J.3    You, L.4    Xu, Z.5    He, B.6    Jablons, D.M.7
  • 5
    • 0032147260 scopus 로고    scopus 로고
    • The national cancer data base report on the relationship of race and national origin to the histology of nasopharyngeal carcinoma
    • Marks J.E., Phillips J.L., Menck H.R. The national cancer data base report on the relationship of race and national origin to the histology of nasopharyngeal carcinoma. Cancer 1998, 83:582-588.
    • (1998) Cancer , vol.83 , pp. 582-588
    • Marks, J.E.1    Phillips, J.L.2    Menck, H.R.3
  • 6
    • 0032203713 scopus 로고    scopus 로고
    • Arabidopsis homologs of a c-Jun coactivator are present both in monomeric form and in the COP9 complex, and their abundance is differentially affected by the pleiotropic cop/det/fus mutations
    • Kwok S.F., Solano R., Tsuge T., Chamovitz D.A., Ecker J.R., Matsui M., Deng X.W. Arabidopsis homologs of a c-Jun coactivator are present both in monomeric form and in the COP9 complex, and their abundance is differentially affected by the pleiotropic cop/det/fus mutations. Plant Cell 1998, 10:1779-1790.
    • (1998) Plant Cell , vol.10 , pp. 1779-1790
    • Kwok, S.F.1    Solano, R.2    Tsuge, T.3    Chamovitz, D.A.4    Ecker, J.R.5    Matsui, M.6    Deng, X.W.7
  • 8
    • 0037145744 scopus 로고    scopus 로고
    • Frequent chromosome 9p losses in histologically normal nasopharyngeal epithelia from southern Chinese
    • Chan A.S., To K.F., Lo K.W., Ding M., Li X., Johnson P., Huang D.P. Frequent chromosome 9p losses in histologically normal nasopharyngeal epithelia from southern Chinese. Int. J. Cancer 2002, 102:300-303.
    • (2002) Int. J. Cancer , vol.102 , pp. 300-303
    • Chan, A.S.1    To, K.F.2    Lo, K.W.3    Ding, M.4    Li, X.5    Johnson, P.6    Huang, D.P.7
  • 12
    • 84859387866 scopus 로고    scopus 로고
    • Jab1/CSN5 negatively regulates p27 and plays a role in the pathogenesis of nasopharyngeal carcinoma
    • Pan Y., Zhang Q., Tian L., Wang X., Fan X., Zhang H., Claret F.X., Yang H. Jab1/CSN5 negatively regulates p27 and plays a role in the pathogenesis of nasopharyngeal carcinoma. Cancer Res. 2012, 72:1890-1900.
    • (2012) Cancer Res. , vol.72 , pp. 1890-1900
    • Pan, Y.1    Zhang, Q.2    Tian, L.3    Wang, X.4    Fan, X.5    Zhang, H.6    Claret, F.X.7    Yang, H.8
  • 13
    • 84879420588 scopus 로고    scopus 로고
    • Suppression of Jab1/CSN5 induces radio- and chemo-sensitivity in nasopharyngeal carcinoma through changes to the DNA damage and repair pathways
    • [Epub ahead of print] PMID:22797071
    • Pan Y., Zhang Q., Atsaves V., Yang H., Claret F.X. Suppression of Jab1/CSN5 induces radio- and chemo-sensitivity in nasopharyngeal carcinoma through changes to the DNA damage and repair pathways. Oncogene 2012, [Epub ahead of print] PMID:22797071. 10.1038/onc.2012.294.
    • (2012) Oncogene
    • Pan, Y.1    Zhang, Q.2    Atsaves, V.3    Yang, H.4    Claret, F.X.5
  • 14
    • 0030581153 scopus 로고    scopus 로고
    • The COP9 complex, a novel multisubunit nuclear regulator involved in light control of a plant developmental switch
    • Chamovitz D.A., Wei N., Osterlund M.T., von Arnim A.G., Staub J.M., Matsui M., Deng X.W. The COP9 complex, a novel multisubunit nuclear regulator involved in light control of a plant developmental switch. Cell 1996, 86:115-121.
    • (1996) Cell , vol.86 , pp. 115-121
    • Chamovitz, D.A.1    Wei, N.2    Osterlund, M.T.3    von Arnim, A.G.4    Staub, J.M.5    Matsui, M.6    Deng, X.W.7
  • 15
    • 0033828048 scopus 로고    scopus 로고
    • The COP9 signalosome: from light signaling to general developmental regulation and back
    • Karniol B., Chamovitz D.A. The COP9 signalosome: from light signaling to general developmental regulation and back. Curr. Opin. Plant Biol. 2000, 3:387-393.
    • (2000) Curr. Opin. Plant Biol. , vol.3 , pp. 387-393
    • Karniol, B.1    Chamovitz, D.A.2
  • 16
    • 0035098524 scopus 로고    scopus 로고
    • JAB1/CSN5 and the COP9 signalosome. A complex situation
    • Chamovitz D.A., Segal D. JAB1/CSN5 and the COP9 signalosome. A complex situation. EMBO Rep. 2001, 2:96-101.
    • (2001) EMBO Rep. , vol.2 , pp. 96-101
    • Chamovitz, D.A.1    Segal, D.2
  • 17
    • 0029761277 scopus 로고    scopus 로고
    • A new group of conserved coactivators that increase the specificity of AP-1 transcription factors
    • Claret F.X., Hibi M., Dhut S., Toda T., Karin M. A new group of conserved coactivators that increase the specificity of AP-1 transcription factors. Nature 1996, 383:453-457.
    • (1996) Nature , vol.383 , pp. 453-457
    • Claret, F.X.1    Hibi, M.2    Dhut, S.3    Toda, T.4    Karin, M.5
  • 19
    • 0037127256 scopus 로고    scopus 로고
    • The cytoplasmic shuttling and subsequent degradation of p27Kip1 mediated by Jab1/CSN5 and the COP9 signalosome complex
    • Tomoda K., Kubota Y., Arata Y., Mori S., Maeda M., Tanaka T., Yoshida M., Yoneda-Kato N., Kato J.Y. The cytoplasmic shuttling and subsequent degradation of p27Kip1 mediated by Jab1/CSN5 and the COP9 signalosome complex. J. Biol. Chem. 2002, 277:2302-2310.
    • (2002) J. Biol. Chem. , vol.277 , pp. 2302-2310
    • Tomoda, K.1    Kubota, Y.2    Arata, Y.3    Mori, S.4    Maeda, M.5    Tanaka, T.6    Yoshida, M.7    Yoneda-Kato, N.8    Kato, J.Y.9
  • 21
    • 0347787959 scopus 로고    scopus 로고
    • COP9 signalosome components play a role in the mating pheromone response of S. cerevisiae
    • Maytal-Kivity V., Piran R., Pick E., Hofmann K., Glickman M.H. COP9 signalosome components play a role in the mating pheromone response of S. cerevisiae. EMBO Rep. 2002, 3:1215-1221.
    • (2002) EMBO Rep. , vol.3 , pp. 1215-1221
    • Maytal-Kivity, V.1    Piran, R.2    Pick, E.3    Hofmann, K.4    Glickman, M.H.5
  • 22
    • 77957914630 scopus 로고    scopus 로고
    • JAB1/CSN5: a new player in cell cycle control and cancer
    • Shackleford T.J., Claret F.X. JAB1/CSN5: a new player in cell cycle control and cancer. Cell Div. 2010, 5:26.
    • (2010) Cell Div. , vol.5 , pp. 26
    • Shackleford, T.J.1    Claret, F.X.2
  • 24
    • 0033545636 scopus 로고    scopus 로고
    • Degradation of the cyclin-dependent-kinase inhibitor p27Kip1 is instigated by Jab1
    • Tomoda K., Kubota Y., Kato J. Degradation of the cyclin-dependent-kinase inhibitor p27Kip1 is instigated by Jab1. Nature 1999, 398:160-165.
    • (1999) Nature , vol.398 , pp. 160-165
    • Tomoda, K.1    Kubota, Y.2    Kato, J.3
  • 25
    • 33745218066 scopus 로고    scopus 로고
    • Jab1 induces the cytoplasmic localization and degradation of p53 in coordination with Hdm2
    • Oh W., Lee E.W., Sung Y.H., Yang M.R., Ghim J., Lee H.W., Song J. Jab1 induces the cytoplasmic localization and degradation of p53 in coordination with Hdm2. J. Biol. Chem. 2006, 281:17457-17465.
    • (2006) J. Biol. Chem. , vol.281 , pp. 17457-17465
    • Oh, W.1    Lee, E.W.2    Sung, Y.H.3    Yang, M.R.4    Ghim, J.5    Lee, H.W.6    Song, J.7
  • 26
    • 0036848655 scopus 로고    scopus 로고
    • CSN5/Jab1 mutations affect axis formation in the Drosophila oocyte by activating a meiotic checkpoint
    • Doronkin S., Djagaeva I., Beckendorf S.K. CSN5/Jab1 mutations affect axis formation in the Drosophila oocyte by activating a meiotic checkpoint. Development 2002, 129:5053-5064.
    • (2002) Development , vol.129 , pp. 5053-5064
    • Doronkin, S.1    Djagaeva, I.2    Beckendorf, S.K.3
  • 27
    • 0036198412 scopus 로고    scopus 로고
    • Jab1 antagonizes TGF-beta signaling by inducing Smad4 degradation
    • Wan M., Cao X., Wu Y., Bai S., Wu L., Shi X., Wang N. Jab1 antagonizes TGF-beta signaling by inducing Smad4 degradation. EMBO Rep. 2002, 3:171-176.
    • (2002) EMBO Rep. , vol.3 , pp. 171-176
    • Wan, M.1    Cao, X.2    Wu, Y.3    Bai, S.4    Wu, L.5    Shi, X.6    Wang, N.7
  • 28
    • 1542314268 scopus 로고    scopus 로고
    • Jab1/CSN5, a component of the COP9 signalosome, regulates transforming growth factor beta signaling by binding to Smad7 and promoting its degradation
    • Kim B.C., Lee H.J., Park S.H., Lee S.R., Karpova T.S., McNally J.G., Felici A., Lee D.K., Kim S.J. Jab1/CSN5, a component of the COP9 signalosome, regulates transforming growth factor beta signaling by binding to Smad7 and promoting its degradation. Mol. Cell. Biol. 2004, 24:2251-2262.
    • (2004) Mol. Cell. Biol. , vol.24 , pp. 2251-2262
    • Kim, B.C.1    Lee, H.J.2    Park, S.H.3    Lee, S.R.4    Karpova, T.S.5    McNally, J.G.6    Felici, A.7    Lee, D.K.8    Kim, S.J.9
  • 29
    • 0034607465 scopus 로고    scopus 로고
    • P38JAB1 binds to the intracellular precursor of the lutropin/choriogonadotropin receptor and promotes its degradation
    • Li S., Liu X., Ascoli M. P38JAB1 binds to the intracellular precursor of the lutropin/choriogonadotropin receptor and promotes its degradation. J. Biol. Chem. 2000, 275:13386-13393.
    • (2000) J. Biol. Chem. , vol.275 , pp. 13386-13393
    • Li, S.1    Liu, X.2    Ascoli, M.3
  • 30
    • 19444377295 scopus 로고    scopus 로고
    • The neuronal POU transcription factor Brn-2 interacts with Jab1, a gene involved in the onset of neurodegenerative diseases
    • Huang Y.T., Iwamoto K., Kurosaki T., Nasu M., Ueda S. The neuronal POU transcription factor Brn-2 interacts with Jab1, a gene involved in the onset of neurodegenerative diseases. Neurosci. Lett. 2005, 382:175-178.
    • (2005) Neurosci. Lett. , vol.382 , pp. 175-178
    • Huang, Y.T.1    Iwamoto, K.2    Kurosaki, T.3    Nasu, M.4    Ueda, S.5
  • 33
    • 0037567489 scopus 로고    scopus 로고
    • Jun activation domain-binding protein 1 expression in breast cancer inversely correlates with the cell cycle inhibitor p27(Kip1)
    • Kouvaraki M.A., Rassidakis G.Z., Tian L., Kumar R., Kittas C., Claret F.X. Jun activation domain-binding protein 1 expression in breast cancer inversely correlates with the cell cycle inhibitor p27(Kip1). Cancer Res. 2003, 63:2977-2981.
    • (2003) Cancer Res. , vol.63 , pp. 2977-2981
    • Kouvaraki, M.A.1    Rassidakis, G.Z.2    Tian, L.3    Kumar, R.4    Kittas, C.5    Claret, F.X.6
  • 35
    • 33745309536 scopus 로고    scopus 로고
    • Overexpression of Jun activation domain-binding protein 1 in nonsmall cell lung cancer and its significance in p27 expression and clinical features
    • Osoegawa A., Yoshino I., Kometani T., Yamaguchi M., Kameyama T., Yohena T., Maehara Y. Overexpression of Jun activation domain-binding protein 1 in nonsmall cell lung cancer and its significance in p27 expression and clinical features. Cancer 2006, 107:154-161.
    • (2006) Cancer , vol.107 , pp. 154-161
    • Osoegawa, A.1    Yoshino, I.2    Kometani, T.3    Yamaguchi, M.4    Kameyama, T.5    Yohena, T.6    Maehara, Y.7
  • 37
    • 11344272136 scopus 로고    scopus 로고
    • Prognostic significance of Jab1 expression in laryngeal squamous cell carcinomas
    • Dong Y., Sui L., Watanabe Y., Yamaguchi F., Hatano N., Tokuda M. Prognostic significance of Jab1 expression in laryngeal squamous cell carcinomas. Clin. Cancer Res. 2005, 11:259-266.
    • (2005) Clin. Cancer Res. , vol.11 , pp. 259-266
    • Dong, Y.1    Sui, L.2    Watanabe, Y.3    Yamaguchi, F.4    Hatano, N.5    Tokuda, M.6
  • 38
    • 48249136165 scopus 로고    scopus 로고
    • Overexpression of Jab1 in hepatocellular carcinoma and its inhibition by peroxisome proliferator-activated receptor{gamma} ligands in vitro and in vivo
    • Hsu M.C., Huang C.C., Chang H.C., Hu T.H., Hung W.C. Overexpression of Jab1 in hepatocellular carcinoma and its inhibition by peroxisome proliferator-activated receptor{gamma} ligands in vitro and in vivo. Clin. Cancer Res. 2008, 14:4045-4052.
    • (2008) Clin. Cancer Res. , vol.14 , pp. 4045-4052
    • Hsu, M.C.1    Huang, C.C.2    Chang, H.C.3    Hu, T.H.4    Hung, W.C.5
  • 39
    • 69249220221 scopus 로고    scopus 로고
    • Cytoplasmic localization of Jab1 and p27 Kip1 might be associated with invasiveness of papillary thyroid carcinoma
    • Ahn J., Hong S.A., Lee S.E., Kim J., Oh Y.S., Park S.J., Chung Y.J. Cytoplasmic localization of Jab1 and p27 Kip1 might be associated with invasiveness of papillary thyroid carcinoma. Endocr. J. 2009, 56:707-713.
    • (2009) Endocr. J. , vol.56 , pp. 707-713
    • Ahn, J.1    Hong, S.A.2    Lee, S.E.3    Kim, J.4    Oh, Y.S.5    Park, S.J.6    Chung, Y.J.7
  • 40
    • 0346689074 scopus 로고    scopus 로고
    • Skp2 and Jab1 expression are associated with inverse expression of p27(KIP1) and poor prognosis in oral squamous cell carcinomas
    • Shintani S., Li C., Mihara M., Hino S., Nakashiro K., Hamakawa H. Skp2 and Jab1 expression are associated with inverse expression of p27(KIP1) and poor prognosis in oral squamous cell carcinomas. Oncology 2003, 65:355-362.
    • (2003) Oncology , vol.65 , pp. 355-362
    • Shintani, S.1    Li, C.2    Mihara, M.3    Hino, S.4    Nakashiro, K.5    Hamakawa, H.6
  • 41
    • 24344433544 scopus 로고    scopus 로고
    • Basic investigation on the development of molecular targeting therapy against cyclin-dependent kinase inhibitor p27Kip1 in head and neck cancer cells
    • Supriatno K., Harada H.Yoshida., Sato M. Basic investigation on the development of molecular targeting therapy against cyclin-dependent kinase inhibitor p27Kip1 in head and neck cancer cells. Int. J. Oncol. 2005, 27:627-635.
    • (2005) Int. J. Oncol. , vol.27 , pp. 627-635
    • Supriatno, K.1    Harada, H.2    Sato, M.3
  • 43
    • 0035675964 scopus 로고    scopus 로고
    • Jab1 expression is associated with inverse expression of p27(kip1) and poor prognosis in epithelial ovarian tumors
    • Sui L., Dong Y., Ohno M., Watanabe Y., Sugimoto K., Tai Y., Tokuda M. Jab1 expression is associated with inverse expression of p27(kip1) and poor prognosis in epithelial ovarian tumors. Clin. Cancer Res. 2001, 7:4130-4135.
    • (2001) Clin. Cancer Res. , vol.7 , pp. 4130-4135
    • Sui, L.1    Dong, Y.2    Ohno, M.3    Watanabe, Y.4    Sugimoto, K.5    Tai, Y.6    Tokuda, M.7
  • 45
    • 0037378534 scopus 로고    scopus 로고
    • A positive autoregulatory loop of LMP1 expression and STAT activation in epithelial cells latently infected with Epstein-barr virus
    • Chen H., Hutt-Fletcher L., Cao L., Hayward S.D. A positive autoregulatory loop of LMP1 expression and STAT activation in epithelial cells latently infected with Epstein-barr virus. J. Virol. 2003, 77:4139-4148.
    • (2003) J. Virol. , vol.77 , pp. 4139-4148
    • Chen, H.1    Hutt-Fletcher, L.2    Cao, L.3    Hayward, S.D.4
  • 47
    • 11344272136 scopus 로고    scopus 로고
    • Prognostic significance of Jab1 expression in laryngeal squamous cell carcinomas
    • Dong Y., Sui L., Watanabe Y., Yamaguchi F., Hatano N., Tokuda M. Prognostic significance of Jab1 expression in laryngeal squamous cell carcinomas. Clin. Cancer Res. 2005, 11:259-266.
    • (2005) Clin. Cancer Res. , vol.11 , pp. 259-266
    • Dong, Y.1    Sui, L.2    Watanabe, Y.3    Yamaguchi, F.4    Hatano, N.5    Tokuda, M.6
  • 48
    • 35948984762 scopus 로고    scopus 로고
    • HER-2/neu transcriptionally activates Jab1 expression via the AKT/beta-catenin pathway in breast cancer cells
    • Hsu M.C., Chang H.C., Hung W.C. HER-2/neu transcriptionally activates Jab1 expression via the AKT/beta-catenin pathway in breast cancer cells. Endocr. Relat. Cancer 2007, 14:655-667.
    • (2007) Endocr. Relat. Cancer , vol.14 , pp. 655-667
    • Hsu, M.C.1    Chang, H.C.2    Hung, W.C.3
  • 50
    • 5644256911 scopus 로고    scopus 로고
    • Multiple functions of Jab1 are required for early embryonic development and growth potential in mice
    • Tomoda K., Yoneda-Kato N., Fukumoto A., Yamanaka S., Kato J.Y. Multiple functions of Jab1 are required for early embryonic development and growth potential in mice. J. Biol. Chem. 2004, 279:43013-43018.
    • (2004) J. Biol. Chem. , vol.279 , pp. 43013-43018
    • Tomoda, K.1    Yoneda-Kato, N.2    Fukumoto, A.3    Yamanaka, S.4    Kato, J.Y.5
  • 52
    • 80455174489 scopus 로고    scopus 로고
    • Nutrient sensing kinases PKA and Sch9 phosphorylate the catalytic domain of the ubiquitin-conjugating enzyme Cdc34
    • Cocklin R., Goebl M. Nutrient sensing kinases PKA and Sch9 phosphorylate the catalytic domain of the ubiquitin-conjugating enzyme Cdc34. PLoS ONE 2011, 6:e27099.
    • (2011) PLoS ONE , vol.6
    • Cocklin, R.1    Goebl, M.2
  • 53
    • 0038329328 scopus 로고    scopus 로고
    • The COP9 signalosome promotes degradation of Cyclin E during early Drosophila oogenesis
    • Doronkin S., Djagaeva I., Beckendorf S.K. The COP9 signalosome promotes degradation of Cyclin E during early Drosophila oogenesis. Dev. Cell 2003, 4:699-710.
    • (2003) Dev. Cell , vol.4 , pp. 699-710
    • Doronkin, S.1    Djagaeva, I.2    Beckendorf, S.K.3
  • 54
  • 55
    • 33750043187 scopus 로고    scopus 로고
    • Depletion of Jab1 inhibits proliferation of pancreatic cancer cell lines
    • Fukumoto A., Tomoda K., Yoneda-Kato N., Nakajima Y., Kato J.Y. Depletion of Jab1 inhibits proliferation of pancreatic cancer cell lines. FEBS Lett. 2006, 580:5836-5844.
    • (2006) FEBS Lett. , vol.580 , pp. 5836-5844
    • Fukumoto, A.1    Tomoda, K.2    Yoneda-Kato, N.3    Nakajima, Y.4    Kato, J.Y.5
  • 56
    • 84857806053 scopus 로고    scopus 로고
    • JAB1 is essential for B cell development and germinal center formation and inversely regulates Fas ligand and Bcl6 expression
    • Sitte S., Glasner J., Jellusova J., Weisel F., Panattoni M., Pardi R., Gessner A. JAB1 is essential for B cell development and germinal center formation and inversely regulates Fas ligand and Bcl6 expression. J. Immunol. 2012, 188:2677-2686.
    • (2012) J. Immunol. , vol.188 , pp. 2677-2686
    • Sitte, S.1    Glasner, J.2    Jellusova, J.3    Weisel, F.4    Panattoni, M.5    Pardi, R.6    Gessner, A.7
  • 57
    • 79958251632 scopus 로고    scopus 로고
    • Fank1 interacts with Jab1 and regulates cell apoptosis via the AP-1 pathway
    • Wang H., Song W., Hu T., Zhang N., Miao S., Zong S., Wang L. Fank1 interacts with Jab1 and regulates cell apoptosis via the AP-1 pathway. Cell. Mol. Life Sci. 2011, 68:2129-2139.
    • (2011) Cell. Mol. Life Sci. , vol.68 , pp. 2129-2139
    • Wang, H.1    Song, W.2    Hu, T.3    Zhang, N.4    Miao, S.5    Zong, S.6    Wang, L.7
  • 59
    • 80053461474 scopus 로고    scopus 로고
    • Jab1/CSN5 mediates E2F dependent expression of mitotic and apoptotic but not DNA replication targets
    • Lu H., Liang X., Issaenko O.A., Hallstrom T.C. Jab1/CSN5 mediates E2F dependent expression of mitotic and apoptotic but not DNA replication targets. Cell Cycle 2011, 10:3317-3326.
    • (2011) Cell Cycle , vol.10 , pp. 3317-3326
    • Lu, H.1    Liang, X.2    Issaenko, O.A.3    Hallstrom, T.C.4
  • 62
    • 0035093737 scopus 로고    scopus 로고
    • DNA double-strand breaks: signaling, repair and the cancer connection
    • Khanna K.K., Jackson S.P. DNA double-strand breaks: signaling, repair and the cancer connection. Nat. Genet. 2001, 27:247-254.
    • (2001) Nat. Genet. , vol.27 , pp. 247-254
    • Khanna, K.K.1    Jackson, S.P.2
  • 63
    • 0035289717 scopus 로고    scopus 로고
    • Chromosomal stability and the DNA double-stranded break connection
    • van Gent D.C., Hoeijmakers J.H., Kanaar R. Chromosomal stability and the DNA double-stranded break connection. Nat. Rev. 2001, 2:196-206.
    • (2001) Nat. Rev. , vol.2 , pp. 196-206
    • van Gent, D.C.1    Hoeijmakers, J.H.2    Kanaar, R.3
  • 64
    • 0026751113 scopus 로고
    • Rad51 protein involved in repair and recombination in S. cerevisiae is a RecA-like protein
    • Shinohara A., Ogawa H., Ogawa T. Rad51 protein involved in repair and recombination in S. cerevisiae is a RecA-like protein. Cell 1992, 69:457-470.
    • (1992) Cell , vol.69 , pp. 457-470
    • Shinohara, A.1    Ogawa, H.2    Ogawa, T.3
  • 65
    • 0035833552 scopus 로고    scopus 로고
    • Structure of the Ku heterodimer bound to DNA and its implications for double-strand break repair
    • Walker J.R., Corpina R.A., Goldberg J. Structure of the Ku heterodimer bound to DNA and its implications for double-strand break repair. Nature 2001, 412:607-614.
    • (2001) Nature , vol.412 , pp. 607-614
    • Walker, J.R.1    Corpina, R.A.2    Goldberg, J.3
  • 67
    • 0032489520 scopus 로고    scopus 로고
    • DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139
    • Rogakou E.P., Pilch D.R., Orr A.H., Ivanova V.S., Bonner W.M. DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139. J. Biol. Chem. 1998, 273:5858-5868.
    • (1998) J. Biol. Chem. , vol.273 , pp. 5858-5868
    • Rogakou, E.P.1    Pilch, D.R.2    Orr, A.H.3    Ivanova, V.S.4    Bonner, W.M.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.