Profiling of behavioral changes and hippocampal gene expression in mice chronically treated with the SSRI paroxetine

Psychopharmacology

Volumn 200, Issue 4, 2008, Pages 557-572

  Sillaber, Inge ^a,b   Panhuysen, Markus ^a,b   Henniger, Markus S H ^a,b   Ohl, Frauke ^a,d   Kühne, Claudia ^a   Pütz, Benno ^a   Pohl, Thomas ^a,b   Deussing, Jan M ^a,c   Paez Pereda, Marcelo ^a,b   Holsboer, Florian ^a  

^a MAX PLANCK INSTITUTE OF PSYCHIATRY   (Germany)

^b Affectis Pharmaceutical AG   (Germany)

^c INSTITUTE OF EPIDEMIOLOGY   (Germany)

^d UTRECHT UNIVERSITY   (Netherlands)

Author keywords

Antidepressant; Behavior; Hippocampus; Microarray; Neurogenesis; Neuroplasiticity

Indexed keywords

ANTIDEPRESSANT AGENT; ENKEPHALIN DERIVATIVE; INHIBIN; NEUROTRANSMITTER; PAROXETINE; SEROTONIN UPTAKE INHIBITOR; VIMENTIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BDNF GENE; BEHAVIOR CHANGE; CONTROLLED STUDY; DEPRESSION; DRUG MECHANISM; EGR1 GENE; GENE; GENE EXPRESSION; GFAP GENE; HIPPOCAMPUS; INHBA GENE; MALE; MOUSE; NERVE CELL PLASTICITY; NONHUMAN; PENK1 GENE; PRIORITY JOURNAL; SOX 11 GENE; STAT3 GENE; TISSUE MICROARRAY; TREATMENT DURATION; VIM GENE;

ANIMALS; ANTIDEPRESSIVE AGENTS, SECOND-GENERATION; BEHAVIOR, ANIMAL; DARKNESS; DEPRESSION; DISEASE MODELS, ANIMAL; GENE EXPRESSION REGULATION; HIPPOCAMPUS; LIGHT; MALE; MICE; MICE, INBRED DBA; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PAROXETINE; SEROTONIN UPTAKE INHIBITORS; SWIMMING;

EID: 52649179941     PISSN: 00333158     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00213-008-1232-6     Document Type: Article

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