메뉴 건너뛰기




Volumn 32, Issue 39, 2012, Pages 13510-13519

Optogenetic analysis of neuronal excitability during global ischemia reveals selective deficits in sensory processing following reperfusion in mouse cortex

Author keywords

[No Author keywords available]

Indexed keywords

CATION CHANNEL; CHANELRHODOPSIN 2; UNCLASSIFIED DRUG;

EID: 84866636413     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.1439-12.2012     Document Type: Article
Times cited : (22)

References (69)
  • 1
    • 34547133175 scopus 로고    scopus 로고
    • An optical neural interface: In vivo control of rodent motor cortex with integrated fiberoptic and optogenetic technology
    • Aravanis AM, Wang LP, Zhang F, Meltzer LA, Mogri MZ, Schneider MB, Deisseroth K (2007) An optical neural interface: in vivo control of rodent motor cortex with integrated fiberoptic and optogenetic technology. J Neural Eng 4:S143-S156.
    • (2007) J Neural Eng , vol.4
    • Aravanis, A.M.1    Wang, L.P.2    Zhang, F.3    Meltzer, L.A.4    Mogri, M.Z.5    Schneider, M.B.6    Deisseroth, K.7
  • 3
    • 0019822988 scopus 로고
    • Thresholds in cerebral ischemia-the ischemic penumbra
    • Astrup J, Siesjö BK, Symon L (1981) Thresholds in cerebral ischemia-the ischemic penumbra. Stroke 12:723-725.
    • (1981) Stroke , vol.12 , pp. 723-725
    • Astrup, J.1    Siesjö, B.K.2    Symon, L.3
  • 4
    • 61449224427 scopus 로고    scopus 로고
    • Automated light-based mapping of motor cortex by photoactivation of channelrhodopsin-2 transgenic mice
    • Ayling OG, Harrison TC, Boyd JD, Goroshkov A, Murphy TH (2009) Automated light-based mapping of motor cortex by photoactivation of channelrhodopsin-2 transgenic mice. Nat Methods 6:219-224.
    • (2009) Nat Methods , vol.6 , pp. 219-224
    • Ayling, O.G.1    Harrison, T.C.2    Boyd, J.D.3    Goroshkov, A.4    Murphy, T.H.5
  • 6
    • 78751535831 scopus 로고    scopus 로고
    • Changes in hippocampal neuronal activity during and after unilateral selective hippocampal ischemia in vivo
    • Barth AM, Mody I (2011) Changes in hippocampal neuronal activity during and after unilateral selective hippocampal ischemia in vivo. J Neurosci 31:851-860.
    • (2011) J Neurosci , vol.31 , pp. 851-860
    • Barth, A.M.1    Mody, I.2
  • 7
    • 41849088871 scopus 로고    scopus 로고
    • Spreading depression enhances human neocortical excitability in vitro
    • Berger M, Speckmann EJ, Pape HC, Gorji A (2008) Spreading depression enhances human neocortical excitability in vitro. Cephalalgia 28:558-562.
    • (2008) Cephalalgia , vol.28 , pp. 558-562
    • Berger, M.1    Speckmann, E.J.2    Pape, H.C.3    Gorji, A.4
  • 9
    • 0031707705 scopus 로고    scopus 로고
    • Mechanisms of motor dysfunction after transient MCA occlusion: Persistent transmission failure in cortical synapses is a major determinant
    • Bolay H, Dalkara T (1998) Mechanisms of motor dysfunction after transient MCA occlusion: persistent transmission failure in cortical synapses is a major determinant. Stroke 29:1988-1993.
    • (1998) Stroke , vol.29 , pp. 1988-1993
    • Bolay, H.1    Dalkara, T.2
  • 10
    • 26444621497 scopus 로고    scopus 로고
    • Millisecondtimescale, genetically targeted optical control of neural activity
    • Boyden ES, Zhang F, Bamberg E, Nagel G, Deisseroth K (2005) Millisecondtimescale, genetically targeted optical control of neural activity. Nat Neurosci 8:1263-1268.
    • (2005) Nat Neurosci , vol.8 , pp. 1263-1268
    • Boyden, E.S.1    Zhang, F.2    Bamberg, E.3    Nagel, G.4    Deisseroth, K.5
  • 12
    • 33244483657 scopus 로고    scopus 로고
    • Time-varying spreading depression waves in rat cortex revealed by optical intrinsic signal imaging
    • Chen S, Li P, Luo W, Gong H, Zeng S, Luo Q (2006a) Time-varying spreading depression waves in rat cortex revealed by optical intrinsic signal imaging. Neurosci Lett 396:132-136.
    • (2006) Neurosci Lett , vol.396 , pp. 132-136
    • Chen, S.1    Li, P.2    Luo, W.3    Gong, H.4    Zeng, S.5    Luo, Q.6
  • 13
    • 33748448115 scopus 로고    scopus 로고
    • In vivo optical reflectance imaging of spreading depression waves in rat brain with and without focal cerebral ischemia
    • Chen S, Feng Z, Li P, Jacques SL, Zeng S, Luo Q (2006b) In vivo optical reflectance imaging of spreading depression waves in rat brain with and without focal cerebral ischemia. J Biomed Opt 11:34002.
    • (2006) J Biomed Opt , vol.11 , pp. 34002
    • Chen, S.1    Feng, Z.2    Li, P.3    Jacques, S.L.4    Zeng, S.5    Luo, Q.6
  • 14
    • 78149431325 scopus 로고    scopus 로고
    • Reducing excessive GABA-mediated tonic inhibition promotes functional recovery after stroke
    • Clarkson AN, Huang BS, Macisaac SE, Mody I, Carmichael ST (2010) Reducing excessive GABA-mediated tonic inhibition promotes functional recovery after stroke. Nature 468:305-309.
    • (2010) Nature , vol.468 , pp. 305-309
    • Clarkson, A.N.1    Huang, B.S.2    Macisaac, S.E.3    Mody, I.4    Carmichael, S.T.5
  • 15
    • 73949140060 scopus 로고    scopus 로고
    • The slow (<1 Hz) rhythm of non-REM sleep: A dialogue between three cardinal oscillators
    • Crunelli V, Hughes SW (2010) The slow (<1 Hz) rhythm of non-REM sleep: a dialogue between three cardinal oscillators. Nat Neurosci 13:9-17.
    • (2010) Nat Neurosci , vol.13 , pp. 9-17
    • Crunelli, V.1    Hughes, S.W.2
  • 16
    • 80053633061 scopus 로고    scopus 로고
    • Cortical excitation and inhibition following focal traumatic brain injury
    • Ding MC, Wang Q, Lo EH, Stanley GB (2011) Cortical excitation and inhibition following focal traumatic brain injury. J Neurosci 31:14085-14094.
    • (2011) J Neurosci , vol.31 , pp. 14085-14094
    • Ding, M.C.1    Wang, Q.2    Lo, E.H.3    Stanley, G.B.4
  • 17
    • 0033199996 scopus 로고    scopus 로고
    • Pathobiology of ischaemic stroke: An integrated view
    • Dirnagl U, Iadecola C, Moskowitz MA (1999) Pathobiology of ischaemic stroke: an integrated view. Trends Neurosci 22:391-397.
    • (1999) Trends Neurosci , vol.22 , pp. 391-397
    • Dirnagl, U.1    Iadecola, C.2    Moskowitz, M.A.3
  • 18
    • 79955142391 scopus 로고    scopus 로고
    • Potent inhibition of anoxic depolarization by the sodium channel blocker dibucaine
    • Douglas HA, Callaway JK, Sword J, Kirov SA, Andrew RD (2011) Potent inhibition of anoxic depolarization by the sodium channel blocker dibucaine. J Neurophysiol 105:1482-1494.
    • (2011) J Neurophysiol , vol.105 , pp. 1482-1494
    • Douglas, H.A.1    Callaway, J.K.2    Sword, J.3    Kirov, S.A.4    Andrew, R.D.5
  • 20
    • 79959873914 scopus 로고    scopus 로고
    • The development and application of optogenetics
    • Fenno L, Yizhar O, Deisseroth K (2011) The development and application of optogenetics. Annu Rev Neurosci 34:389-412.
    • (2011) Annu Rev Neurosci , vol.34 , pp. 389-412
    • Fenno, L.1    Yizhar, O.2    Deisseroth, K.3
  • 21
    • 6044224992 scopus 로고    scopus 로고
    • Hyperexcitabilityassociated rapid plasticity after a focal cerebral ischemia
    • Fujioka H, Kaneko H, Suzuki SS, Mabuchi K (2004) Hyperexcitabilityassociated rapid plasticity after a focal cerebral ischemia. Stroke 35:e346-e348.
    • (2004) Stroke , vol.35
    • Fujioka, H.1    Kaneko, H.2    Suzuki, S.S.3    Mabuchi, K.4
  • 22
    • 0032432819 scopus 로고    scopus 로고
    • Transient neurophysiological changes in CA3 neurons and dentate granule cells after severe forebrain ischemia in vivo
    • Gao TM, Howard EM, Xu ZC (1998) Transient neurophysiological changes in CA3 neurons and dentate granule cells after severe forebrain ischemia in vivo. J Neurophysiol 80:2860-2869.
    • (1998) J Neurophysiol , vol.80 , pp. 2860-2869
    • Gao, T.M.1    Howard, E.M.2    Xu, Z.C.3
  • 23
    • 68249125659 scopus 로고    scopus 로고
    • Simple and cost-effective hardware and software for functional brain mapping using intrinsic optical signal imaging
    • Harrison TC, Sigler A, Murphy TH (2009) Simple and cost-effective hardware and software for functional brain mapping using intrinsic optical signal imaging. J Neurosci Methods 182:211-218.
    • (2009) J Neurosci Methods , vol.182 , pp. 211-218
    • Harrison, T.C.1    Sigler, A.2    Murphy, T.H.3
  • 24
    • 84860272181 scopus 로고    scopus 로고
    • Distinct cortical circuit mechanisms for complex forelimb movement and motor map topography
    • Harrison TC, Ayling OG, Murphy TH (2012) Distinct cortical circuit mechanisms for complex forelimb movement and motor map topography. Neuron 74:397-409.
    • (2012) Neuron , vol.74 , pp. 397-409
    • Harrison, T.C.1    Ayling, O.G.2    Murphy, T.H.3
  • 25
    • 84856457578 scopus 로고    scopus 로고
    • Ischemic cerebral damage: An appraisal of synaptic failure
    • Hofmeijer J, van Putten MJ (2012) Ischemic cerebral damage: an appraisal of synaptic failure. Stroke 43:607-615.
    • (2012) Stroke , vol.43 , pp. 607-615
    • Hofmeijer, J.1    van Putten, M.J.2
  • 26
    • 33845547792 scopus 로고    scopus 로고
    • Pathophysiology and therapy of experimental stroke
    • Hossmann KA (2006) Pathophysiology and therapy of experimental stroke. Cell Mol Neurobiol 26:1057-1083.
    • (2006) Cell Mol Neurobiol , vol.26 , pp. 1057-1083
    • Hossmann, K.A.1
  • 27
    • 0035094866 scopus 로고    scopus 로고
    • Anoxic depolarization mediates acute damage independent of glutamate in neocortical brain slices
    • Jarvis CR, Anderson TR, Andrew RD (2001) Anoxic depolarization mediates acute damage independent of glutamate in neocortical brain slices. Cereb Cortex 11:249-259.
    • (2001) Cereb Cortex , vol.11 , pp. 249-259
    • Jarvis, C.R.1    Anderson, T.R.2    Andrew, R.D.3
  • 30
    • 0001099704 scopus 로고
    • Spreading depression of activity in the cerebral cortex
    • Leao AAP (1944) Spreading depression of activity in the cerebral cortex. J Neurophysiol 7:359-390.
    • (1944) J Neurophysiol , vol.7 , pp. 359-390
    • Leao, A.A.P.1
  • 31
    • 0033600277 scopus 로고    scopus 로고
    • The changing landscape of ischaemic brain injury mechanisms
    • Lee JM, Zipfel GJ, Choi DW (1999) The changing landscape of ischaemic brain injury mechanisms. Nature 399:A7-A14.
    • (1999) Nature , vol.399
    • Lee, J.M.1    Zipfel, G.J.2    Choi, D.W.3
  • 32
    • 0022918482 scopus 로고
    • Comparison of the somatosensory evoked potential and the direct cortical response following severe incomplete global ischemia: Selective vulnerability of the white matter conduction pathways
    • Lesnick JE, Coyer PE, Michele JJ, Welsh FA, Simeone FA (1986) Comparison of the somatosensory evoked potential and the direct cortical response following severe incomplete global ischemia: selective vulnerability of the white matter conduction pathways. Stroke 17:1247-1250.
    • (1986) Stroke , vol.17 , pp. 1247-1250
    • Lesnick, J.E.1    Coyer, P.E.2    Michele, J.J.3    Welsh, F.A.4    Simeone, F.A.5
  • 33
    • 64449086893 scopus 로고    scopus 로고
    • Transient enhancement of inhibitory synaptic transmission in hippocampal CA1 pyramidal neurons after cerebral ischemia
    • Liang R, Pang ZP, Deng P, Xu ZC (2009) Transient enhancement of inhibitory synaptic transmission in hippocampal CA1 pyramidal neurons after cerebral ischemia. Neuroscience 160:412-418.
    • (2009) Neuroscience , vol.160 , pp. 412-418
    • Liang, R.1    Pang, Z.P.2    Deng, P.3    Xu, Z.C.4
  • 34
    • 58149349792 scopus 로고    scopus 로고
    • Two-photon imaging during prolonged middle cerebral artery occlusion in mice reveals recovery of dendritic structure after reperfusion
    • Li P, Murphy TH (2008) Two-photon imaging during prolonged middle cerebral artery occlusion in mice reveals recovery of dendritic structure after reperfusion. J Neurosci 28:11970-11979.
    • (2008) J Neurosci , vol.28 , pp. 11970-11979
    • Li, P.1    Murphy, T.H.2
  • 35
    • 60849122213 scopus 로고    scopus 로고
    • Enhancement of inhibitory synaptic transmission in large aspiny neurons after transient cerebral ischemia
    • Li Y, Lei Z, Xu ZC (2009) Enhancement of inhibitory synaptic transmission in large aspiny neurons after transient cerebral ischemia. Neuroscience 159:670-681.
    • (2009) Neuroscience , vol.159 , pp. 670-681
    • Li, Y.1    Lei, Z.2    Xu, Z.C.3
  • 36
    • 84863255188 scopus 로고    scopus 로고
    • In vivo large-scale cortical mapping using channelrhodopsin-2 stimulation in transgenic mice reveals asymmetric and reciprocal relationships between cortical areas
    • Lim DH, Mohajerani MH, Ledue J, Boyd J, Chen S, Murphy TH (2012) In vivo large-scale cortical mapping using channelrhodopsin-2 stimulation in transgenic mice reveals asymmetric and reciprocal relationships between cortical areas. Front Neural Circuits 6:11.
    • (2012) Front Neural Circuits , vol.6 , pp. 11
    • Lim, D.H.1    Mohajerani, M.H.2    Ledue, J.3    Boyd, J.4    Chen, S.5    Murphy, T.H.6
  • 37
    • 73649096895 scopus 로고    scopus 로고
    • Reversible cyclosporin A-sensitive mitochondrial depolarization occurs within minutes of stroke onset in mouse somatosensory cortex in vivo: A two-photon imaging study
    • Liu RR, Murphy TH (2009) Reversible cyclosporin A-sensitive mitochondrial depolarization occurs within minutes of stroke onset in mouse somatosensory cortex in vivo: a two-photon imaging study. J Biol Chem 284:36109-36117.
    • (2009) J Biol Chem , vol.284 , pp. 36109-36117
    • Liu, R.R.1    Murphy, T.H.2
  • 38
    • 0033681557 scopus 로고    scopus 로고
    • Regulation of AMPA receptor-mediated synaptic transmission by clathrin-dependent receptor internalization
    • Man HY, Lin JW, Ju WH, Ahmadian G, Liu L, Becker LE, Sheng M, Wang YT (2000) Regulation of AMPA receptor-mediated synaptic transmission by clathrin-dependent receptor internalization. Neuron 25:649-662.
    • (2000) Neuron , vol.25 , pp. 649-662
    • Man, H.Y.1    Lin, J.W.2    Ju, W.H.3    Ahmadian, G.4    Liu, L.5    Becker, L.E.6    Sheng, M.7    Wang, Y.T.8
  • 39
    • 70350104716 scopus 로고    scopus 로고
    • The optogenetic catechism
    • Miesenböck G (2009) The optogenetic catechism. Science 326:395-399.
    • (2009) Science , vol.326 , pp. 395-399
    • Miesenböck, G.1
  • 40
    • 77949382128 scopus 로고    scopus 로고
    • Mirrored bilateral slow-wave cortical activity within local circuits revealed by fast bihemispheric voltage-sensitive dye imaging in anesthetized and awake mice
    • Mohajerani MH, McVea DA, Fingas M, Murphy TH (2010) Mirrored bilateral slow-wave cortical activity within local circuits revealed by fast bihemispheric voltage-sensitive dye imaging in anesthetized and awake mice. J Neurosci 30:3745-3751.
    • (2010) J Neurosci , vol.30 , pp. 3745-3751
    • Mohajerani, M.H.1    McVea, D.A.2    Fingas, M.3    Murphy, T.H.4
  • 41
    • 79959355101 scopus 로고    scopus 로고
    • Targeted ministrokes produce changes in interhemispheric sensory signal processing that are indicative of disinhibition within minutes
    • Mohajerani MH, Aminoltejari K, Murphy TH (2011) Targeted ministrokes produce changes in interhemispheric sensory signal processing that are indicative of disinhibition within minutes. Proc Natl Acad Sci U S A 108:E183-E191.
    • (2011) Proc Natl Acad Sci U S A , vol.108
    • Mohajerani, M.H.1    Aminoltejari, K.2    Murphy, T.H.3
  • 42
    • 79551558838 scopus 로고    scopus 로고
    • Absence of large-scale dendritic plasticity of layer 5 pyramidal neurons in peri-infarct cortex
    • Mostany R, Portera-Cailliau C (2011) Absence of large-scale dendritic plasticity of layer 5 pyramidal neurons in peri-infarct cortex. J Neurosci 31:1734-1738.
    • (2011) J Neurosci , vol.31 , pp. 1734-1738
    • Mostany, R.1    Portera-Cailliau, C.2
  • 43
    • 84866667615 scopus 로고    scopus 로고
    • Two-photon imaging of neuronal structural plasticity in mice during and after ischemia
    • Helmchen F, Konnerth A, eds). New York: Cold Spring Harbor Laboratory
    • Murphy TH (2011) Two-photon imaging of neuronal structural plasticity in mice during and after ischemia. In: Imaging in neuroscience: a laboratory mannual, Ed 1 (Helmchen F, Konnerth A, eds). New York: Cold Spring Harbor Laboratory.
    • (2011) Imaging In Neuroscience: A Laboratory Mannual , pp. 1
    • Murphy, T.H.1
  • 44
    • 70450267518 scopus 로고    scopus 로고
    • Plasticity during stroke recovery: From synapse to behaviour
    • Murphy TH, Corbett D (2009) Plasticity during stroke recovery: from synapse to behaviour. Nat Rev Neurosci 10:861-872.
    • (2009) Nat Rev Neurosci , vol.10 , pp. 861-872
    • Murphy, T.H.1    Corbett, D.2
  • 45
    • 39549116502 scopus 로고    scopus 로고
    • Two-photon imaging of stroke onset in vivo reveals that NMDA-receptor independent ischemic depolarization is the major cause of rapid reversible damage to dendrites and spines
    • Murphy TH, Li P, Betts K, Liu R (2008) Two-photon imaging of stroke onset in vivo reveals that NMDA-receptor independent ischemic depolarization is the major cause of rapid reversible damage to dendrites and spines. J Neurosci 28:1756-1772.
    • (2008) J Neurosci , vol.28 , pp. 1756-1772
    • Murphy, T.H.1    Li, P.2    Betts, K.3    Liu, R.4
  • 47
    • 0029692038 scopus 로고    scopus 로고
    • Spreading depression as a contributor to ischemic brain damage
    • Nedergaard M (1996) Spreading depression as a contributor to ischemic brain damage. Adv Neurol 71:75-83.
    • (1996) Adv Neurol , vol.71 , pp. 75-83
    • Nedergaard, M.1
  • 48
    • 0033963964 scopus 로고    scopus 로고
    • Glutamate does not mediate acute neuronal damage after spreading depression induced by O2/glucose deprivation in the hippocampal slice
    • Obeidat AS, Jarvis CR, Andrew RD (2000) Glutamate does not mediate acute neuronal damage after spreading depression induced by O2/glucose deprivation in the hippocampal slice. J Cereb Blood Flow Metab 20:412-422.
    • (2000) J Cereb Blood Flow Metab , vol.20 , pp. 412-422
    • Obeidat, A.S.1    Jarvis, C.R.2    Andrew, R.D.3
  • 49
    • 0037115041 scopus 로고    scopus 로고
    • Depression of fast excitatory synaptic transmission in large aspiny neurons of the neostriatum after transient forebrain ischemia
    • Pang ZP, Deng P, Ruan YW, Xu ZC (2002) Depression of fast excitatory synaptic transmission in large aspiny neurons of the neostriatum after transient forebrain ischemia. J Neurosci 22:10948-10957.
    • (2002) J Neurosci , vol.22 , pp. 10948-10957
    • Pang, Z.P.1    Deng, P.2    Ruan, Y.W.3    Xu, Z.C.4
  • 50
    • 77950970208 scopus 로고    scopus 로고
    • Focal cortical infarcts alter intrinsic excitability and synaptic excitation in the reticular thalamic nucleus
    • Paz JT, Christian CA, Parada I, Prince DA, Huguenard JR (2010) Focal cortical infarcts alter intrinsic excitability and synaptic excitation in the reticular thalamic nucleus. J Neurosci 30:5465-5479.
    • (2010) J Neurosci , vol.30 , pp. 5465-5479
    • Paz, J.T.1    Christian, C.A.2    Parada, I.3    Prince, D.A.4    Huguenard, J.R.5
  • 51
    • 34247548430 scopus 로고    scopus 로고
    • Channelrhodopsin-2- assisted circuit mapping of long-range callosal projections
    • Petreanu L, Huber D, Sobczyk A, Svoboda K (2007) Channelrhodopsin-2- assisted circuit mapping of long-range callosal projections. Nat Neurosci 10:663-668.
    • (2007) Nat Neurosci , vol.10 , pp. 663-668
    • Petreanu, L.1    Huber, D.2    Sobczyk, A.3    Svoboda, K.4
  • 52
    • 3042526258 scopus 로고    scopus 로고
    • Unsupervised spike detection and sorting with wavelets and superparamagnetic clustering
    • Quiroga RQ, Nadasdy Z, Ben-Shaul Y (2004) Unsupervised spike detection and sorting with wavelets and superparamagnetic clustering. Neural Comput 16:1661-1687.
    • (2004) Neural Comput , vol.16 , pp. 1661-1687
    • Quiroga, R.Q.1    Nadasdy, Z.2    Ben-Shaul, Y.3
  • 53
    • 0036897551 scopus 로고    scopus 로고
    • Widespread and longlasting alterations in GABA(A)-receptor subtypes after focal cortical infarcts in rats: Mediation by NMDA-dependent processes
    • Redecker C, Wang W, Fritschy JM, Witte OW (2002) Widespread and longlasting alterations in GABA(A)-receptor subtypes after focal cortical infarcts in rats: mediation by NMDA-dependent processes. J Cereb Blood Flow Metab 22:1463-1475.
    • (2002) J Cereb Blood Flow Metab , vol.22 , pp. 1463-1475
    • Redecker, C.1    Wang, W.2    Fritschy, J.M.3    Witte, O.W.4
  • 54
    • 77954838959 scopus 로고    scopus 로고
    • Recurrent spontaneous spreading depolarizations facilitate acute dendritic injury in the ischemic penumbra
    • Risher WC, Ard D, Yuan J, Kirov SA (2010) Recurrent spontaneous spreading depolarizations facilitate acute dendritic injury in the ischemic penumbra. J Neurosci 30:9859-9868.
    • (2010) J Neurosci , vol.30 , pp. 9859-9868
    • Risher, W.C.1    Ard, D.2    Yuan, J.3    Kirov, S.A.4
  • 55
    • 79960338590 scopus 로고    scopus 로고
    • Dibucaine mitigates spreading depolarization in human neocortical slices and prevents acute dendritic injury in the ischemic rodent neocortex
    • Risher WC, Lee MR, Fomitcheva IV, Hess DC, Kirov SA (2011) Dibucaine mitigates spreading depolarization in human neocortical slices and prevents acute dendritic injury in the ischemic rodent neocortex. PLoS One 6:e22351.
    • (2011) PLoS One , vol.6
    • Risher, W.C.1    Lee, M.R.2    Fomitcheva, I.V.3    Hess, D.C.4    Kirov, S.A.5
  • 56
    • 0029784840 scopus 로고    scopus 로고
    • Neuronal hyperexcitability and reduction of GABAA-receptor expression in the surround of cerebral photothrombosis
    • Schiene K, Bruehl C, Zilles K, Qü M, Hagemann G, Kraemer M, Witte OW (1996) Neuronal hyperexcitability and reduction of GABAA-receptor expression in the surround of cerebral photothrombosis. J Cereb Blood Flow Metab 16:906-914.
    • (1996) J Cereb Blood Flow Metab , vol.16 , pp. 906-914
    • Schiene, K.1    Bruehl, C.2    Zilles, K.3    Qü, M.4    Hagemann, G.5    Kraemer, M.6    Witte, O.W.7
  • 57
    • 78650101890 scopus 로고    scopus 로고
    • Channelrhodopsin as a tool to investigate synaptic transmission and plasticity
    • Schoenenberger P, Schärer YP, Oertner TG (2011) Channelrhodopsin as a tool to investigate synaptic transmission and plasticity. Exp Physiol 96:34-39.
    • (2011) Exp Physiol , vol.96 , pp. 34-39
    • Schoenenberger, P.1    Schärer, Y.P.2    Oertner, T.G.3
  • 58
    • 84855585769 scopus 로고    scopus 로고
    • Hemodynamic responses evoked by neuronal stimulation via channelrhodopsin-2 can be independent of intracortical glutamatergic synaptic transmission
    • Scott NA, Murphy TH (2012) Hemodynamic responses evoked by neuronal stimulation via channelrhodopsin-2 can be independent of intracortical glutamatergic synaptic transmission. PLoS One 7:e29859.
    • (2012) PLoS One , vol.7
    • Scott, N.A.1    Murphy, T.H.2
  • 60
    • 14644440194 scopus 로고    scopus 로고
    • Depolarisation phenomena in traumatic and ischaemic brain injury
    • Strong AJ, Dardis R (2005) Depolarisation phenomena in traumatic and ischaemic brain injury. Adv Tech Stand Neurosurg 30:3-49.
    • (2005) Adv Tech Stand Neurosurg , vol.30 , pp. 3-49
    • Strong, A.J.1    Dardis, R.2
  • 62
    • 84857781899 scopus 로고    scopus 로고
    • Moderate or deep local hypothermia does not prevent the onset of ischemia-induced dendritic damage
    • Tran S, Chen S, Liu RR, Xie Y, Murphy TH (2012) Moderate or deep local hypothermia does not prevent the onset of ischemia-induced dendritic damage. J Cereb Blood Flow Metab 32:437-442.
    • (2012) J Cereb Blood Flow Metab , vol.32 , pp. 437-442
    • Tran, S.1    Chen, S.2    Liu, R.R.3    Xie, Y.4    Murphy, T.H.5
  • 64
    • 84856778081 scopus 로고    scopus 로고
    • Short- and longlatency somatosensory neuronal responses reveal selective brain injury and effect of hypothermia in global hypoxic ischemia
    • Wu D, Xiong W, Jia X, Geocadin RG, Thakor NV (2012) Short- and longlatency somatosensory neuronal responses reveal selective brain injury and effect of hypothermia in global hypoxic ischemia. J Neurophysiol 107:1164-1171.
    • (2012) J Neurophysiol , vol.107 , pp. 1164-1171
    • Wu, D.1    Xiong, W.2    Jia, X.3    Geocadin, R.G.4    Thakor, N.V.5
  • 65
    • 0028288530 scopus 로고
    • Responses of CA1 pyramidal neurons in rat hippocampus to transient forebrain ischemia: An in vivo intracellular recording study
    • Xu ZC, Pulsinelli WA (1994) Responses of CA1 pyramidal neurons in rat hippocampus to transient forebrain ischemia: an in vivo intracellular recording study. Neurosci Lett 171:187-191.
    • (1994) Neurosci Lett , vol.171 , pp. 187-191
    • Xu, Z.C.1    Pulsinelli, W.A.2
  • 66
    • 0029761570 scopus 로고    scopus 로고
    • Electrophysiological changes of CA1 pyramidal neurons following transient forebrain ischemia: An in vivo intracellular recording and staining study
    • Xu ZC, Pulsinelli WA (1996) Electrophysiological changes of CA1 pyramidal neurons following transient forebrain ischemia: an in vivo intracellular recording and staining study. J Neurophysiol 76:1689-1697.
    • (1996) J Neurophysiol , vol.76 , pp. 1689-1697
    • Xu, Z.C.1    Pulsinelli, W.A.2
  • 68
    • 20044374010 scopus 로고    scopus 로고
    • Rapid reversible changes in dendritic spine structure in vivo gated by the degree of ischemia
    • Zhang S, Boyd J, Delaney K, Murphy TH (2005) Rapid reversible changes in dendritic spine structure in vivo gated by the degree of ischemia. J Neurosci 25:5333-5338.
    • (2005) J Neurosci , vol.25 , pp. 5333-5338
    • Zhang, S.1    Boyd, J.2    Delaney, K.3    Murphy, T.H.4
  • 69
    • 33645963185 scopus 로고    scopus 로고
    • Enhancement of excitatory synaptic transmission in spiny neurons after transient forebrain ischemia
    • Zhang Y, Deng P, Li Y, Xu ZC (2006) Enhancement of excitatory synaptic transmission in spiny neurons after transient forebrain ischemia. J Neurophysiol 95:1537-1544.
    • (2006) J Neurophysiol , vol.95 , pp. 1537-1544
    • Zhang, Y.1    Deng, P.2    Li, Y.3    Xu, Z.C.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.