Simple and cost-effective hardware and software for functional brain mapping using intrinsic optical signal imaging

Journal of Neuroscience Methods

Volumn 182, Issue 2, 2009, Pages 211-218

  Harrison, Thomas C ^a,b   Sigler, Albrecht ^a,b   Murphy, Timothy H ^a,b  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^b UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

Brain mapping; Cranial surgery; In vivo imaging; LED light sources; Mouse; Sensory cortex

Indexed keywords

ANIMAL EXPERIMENT; ARTICLE; BRAIN TISSUE; CAMERA; COMPUTER; COMPUTER PROGRAM; CONTROLLED STUDY; FINANCIAL MANAGEMENT; IMAGE PROCESSING; IMAGE QUALITY; LENS; LIGHT; LIGHT EMITTING DIODE; MICROSCOPE; MICROSCOPY; MOUSE; NEUROIMAGING; NONHUMAN; PRIORITY JOURNAL; SIGNAL PROCESSING; SURGICAL TECHNIQUE;

ANIMALS; BRAIN MAPPING; CEREBRAL CORTEX; COST-BENEFIT ANALYSIS; DATA INTERPRETATION, STATISTICAL; ELECTRONICS; EQUIPMENT DESIGN; IMAGE PROCESSING, COMPUTER-ASSISTED; LIGHT; MICE; SOFTWARE; SOMATOSENSORY CORTEX;

EID: 68249125659     PISSN: 01650270     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jneumeth.2009.06.021     Document Type: Article

References (31)

1. Albeanu D.F., Soucy E., Sato T.F., Meister M., and Murthy V.N. LED arrays as cost effective and efficient light sources for widefield microscopy. PLoS One 3 (2008) e2146
2. Andrew R.D., and Macvicar B.A. Imaging cell-volume changes and neuronal excitation in the hippocampal slice. Neuroscience 62 (1994) 371-383
3. Bakin J.S., Kwon M.C., Masino S.A., Weinberger N.M., and Frostig R.D. Suprathreshold auditory cortex activation visualized by intrinsic signal optical imaging. Cereb Cortex 6 (1996) 120-130
4. Beach J.M., and Duling B.R. A light-emitting diode light standard for photo-microscopy and videomicroscopy. J Microsc (Oxf) 172 (1993) 41-48
5. Bonhoeffer T., and Grinvald A. The layout of iso-orientation domains in area 18 of cat visual cortex: optical imaging reveals a pinwheel-like organization. J Neurosci 13 (1993) 4157-4180
6. Brown C.E., Li P., Boyd J.D., Delaney K.R., and Murphy T.H. Extensive turnover of dendritic spines and vascular remodeling in cortical tissues recovering from stroke. J Neurosci 27 (2007) 4101-4109
7. Burgess S.A., Bouchard M.B., Yuan B.H., and Hillman E.M.C. Simultaneous multiwavelength laminar optical tomography. Opt Lett 33 (2008) 2710-2712
8. Cescon C., Madeleine P., Graven-Nielsen T., Merletti R., and Farina D. Two-dimensional spatial distribution of surface mechanomyographical response to single motor unit activity. J Neurosci Methods 159 (2007) 19-25
9. Chen B., Trachtenberg J.T., Holtmaat A.J., and Svoboda K. Long-term, high-resolution imaging in the neocortex in vivo. In: Goldman R.D., and Spector D.L. (Eds). Live cell imaging: a laboratory manual (2004), Cold Spring Harbor Laboratory Press, Cold Spring Harbor 423-434
10. Cohen L.B. Changes in neuron structure during action potential propagation and synaptic transmission. Physiol Rev 53 (1973) 373-418
11. Dunn A.K., Devor A., Bolay H., Andermann M.L., Moskowitz M.A., Dale A.M., et al. Simultaneous imaging of total cerebral hemoglobin concentration, oxygenation, and blood flow during functional activation. Opt Lett 28 (2003) 28-30
12. Frostig R.D., Lieke E.E., Tso D.Y., and Grinvald A. Cortical functional architecture and local coupling between neuronal-activity and the microcirculation revealed by in vivo high-resolution optical imaging of intrinsic signals. Proc Natl Acad Sci USA 87 (1990) 6082-6086
13. Grinvald A., Frostig R.D., Lieke E., and Hildesheim R. Optical imaging of neuronal-activity. Physiol Rev 68 (1988) 1285-1366
14. Grinvald A., Lieke E., Frostig R.D., Gilbert C.D., and Wiesel T.N. Functional architecture of cortex revealed by optical imaging of intrinsic signals. Nature 324 (1986) 361-364
15. Grutzendler J., and Gan W.-B. A practical guide: long-term two-photon transcranial imaging of synaptic structures in the living brain. In: Yuste R., Konnerth A., and Masters B.R. (Eds). Imaging in neuroscience and development: a laboratory manual (2006), Cold Spring Harbor Laboratory Press, Cold Spring Harbor 185-191
16. Jones P.B., Shin H.K., Boas D.A., Hyman B.T., Moskowitz M.A., Ayata C., et al. Simultaneous multispectral reflectance imaging and laser speckle flowmetry of cerebral blood flow and oxygen metabolism in focal cerebral ischemia. J Biomed Opt (2008) 13
17. Joshi I., and Andrew R.D. Imaging anoxic depolarization during ischemia-like conditions in the mouse hemi-brain slice. J Neurophysiol 85 (2001) 414-424
18. Masino S.A., Kwon M.C., Dory Y., and Frostig R.D. Characterization of functional organization within rat barrel cortex using intrinsic signal optical imaging through a thinned skull. Proc Natl Acad Sci USA 90 (1993) 9998-10002
19. Mostany R., and Portera-Cailliau C. A craniotomy surgery procedure for chronic brain imaging. JoVE (2008) 12
20. Nishimura M., Shirasawa H., and Song W.-J. A light-emitting diode light source for imaging of neural activities with voltage-sensitive dyes. Neurosci Res 54 (2006) 230-234
21. Pons T.P., Garraghty P.E., Ommaya A.K., Kaas J.H., Taub E., and Mishkin M. Massive cortical reorganization after sensory deafferentation in adult macaques. Science 252 (1991) 1857-1860
22. Pouratian N., and Toga A.W. In: Toga A.W., and Mazziotta J.C. (Eds). Brain mapping: the methods (2002), Academic Press, New York
23. Ratzlaff E.H., and Grinvald A. A tandem-lens epifluorescence macroscope-hundred-fold brightness advantage for wide-field imaging. J Neurosci Methods 36 (1991) 127-137
24. Rubin B.D., and Katz L.C. Optical imaging of odorant representations in the mammalian olfactory bulb. Neuron 23 (1999) 499-511
25. Schummers J., Yu H.B., and Sur M. Tuned responses of astrocytes and their influence on hemodynamic signals in the visual cortex. Science 320 (2008) 1638-1643
26. Sigler A., Goroshkov A., and Murphy T.H. Hardware and methodology for targeting single brain arterioles for photothrombotic stroke on an upright microscope. J Neurosci Methods 170 (2008) 35-44
27. Stosiek C., Garaschuk O., Holthoff K., and Konnerth A. In vivo two-photon calcium imaging of neuronal networks. Proc Natl Acad Sci USA 100 (2003) 7319-7324
28. Winship I.R., and Murphy T.H. In vivo calcium imaging reveals functional rewiring of single somatosensory neurons after stroke. J Neurosci 28 (2008) 6592-6606
29. Xu H.T., Pan F., Yang G., and Gan W.B. Choice of cranial window type for in vivo imaging affects dendritic spine turnover in the cortex. Nat Neurosci 10 (2007) 549-551
30. Yoder E.J., and Kleinfeld D. Cortical imaging through the two-photon excitation laser intact mouse skull using scanning microscopy. Microsc Res Tech 56 (2002) 304-305
31. Zhang S.X., and Murphy T.H. Imaging the impact of cortical microcirculation on synaptic structure and sensory-evoked hemodynamic responses in vivo. PLoS Biol 5 (2007) 1152-1167