Dibucaine mitigates spreading depolarization in human neocortical slices and prevents acute dendritic injury in the ischemic rodent neocortex

PLoS ONE

Volumn 6, Issue 7, 2011, Pages

  Risher, W Christopher ^a,b   Lee, Mark R ^a,c   Fomitcheva, Ioulia V ^a   Hess, David C ^a   Kirov, Sergei A ^a  

^a MEDICAL COLLEGE OF GEORGIA   (United States)

^b DUKE UNIVERSITY MEDICAL CENTER   (United States)

^c DELL INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CINCHOCAINE;

ACUTE DENDRITIC INJURY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN DISEASE; BRAIN FUNCTION; CONTROLLED STUDY; DENDRITE; DEPOLARIZATION; DRUG ACTIVITY; DRUG EFFICACY; EXCITATORY POSTSYNAPTIC POTENTIAL; FEMALE; HUMAN; HUMAN TISSUE; LASER MICROSCOPY; LATENT PERIOD; MALE; MOUSE; NEOCORTEX; NONHUMAN; PHYLOGENY; REPOLARIZATION; STROKE; SYNAPTIC TRANSMISSION; TRANSGENE; ANIMAL; BRAIN ISCHEMIA; C57BL MOUSE; CHILD; DRUG EFFECT; IN VITRO STUDY; PATHOLOGY; PATHOPHYSIOLOGY; SPREADING CORTICAL DEPRESSION;

RODENTIA; STROPHANTHUS GRATUS;

ANIMALS; BRAIN ISCHEMIA; CHILD; CORTICAL SPREADING DEPRESSION; DENDRITES; DIBUCAINE; FEMALE; HUMANS; MALE; MICE; MICE, INBRED C57BL; NEOCORTEX;

EID: 79960338590     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0022351     Document Type: Article

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