Spreading depression enhances human neocortical excitability in vitro

Cephalalgia

Volumn 28, Issue 5, 2008, Pages 558-562

  Berger, M ^a   Speckmann, E J ^a   Pape, H C ^a   Gorji, A ^a  

^a UNIVERSITY OF MÜNSTER   (Germany)

Author keywords

Headache; Neocortex; Neuronal activity; Synapse

Indexed keywords

ARTICLE; COMPLEX PARTIAL SEIZURE; EPILEPSY; EXCITATORY POSTSYNAPTIC POTENTIAL; HUMAN; HUMAN TISSUE; IN VITRO STUDY; LONG TERM POTENTIATION; MIGRAINE WITH AURA; NEOCORTEX; NERVE CELL EXCITABILITY; SIMPLE PARTIAL SEIZURE; SPREADING CORTICAL DEPRESSION; SYNAPSE;

ACTION POTENTIALS; ADOLESCENT; ADULT; BIOLOGICAL CLOCKS; CELLS, CULTURED; FEMALE; HUMANS; MALE; MIDDLE AGED; NEOCORTEX; NERVE NET; SPREADING CORTICAL DEPRESSION;

EID: 41849088871     PISSN: 03331024     EISSN: 14682982     Source Type: Journal    
DOI: 10.1111/j.1468-2982.2008.01556.x     Document Type: Article

References (17)

1. Somjen GG. Mechanisms of spreading depression and hypoxic spreading depression-like depolarization. Physiol Rev 2001 81 : 1065 96.
2. Gorji A. Spreading depression: a review of the clinical relevance. Brain Res Brain Res Rev 2001 38 : 33 60.
3. Goadsby PJ. Recent advances in understanding migraine mechanisms, molecules and therapeutics. Trends Mol Med 2007 13 : 39 44.
4. Moskowitz MA. Pathophysiology of headache - past and present. Headache 2007 47 (Suppl. 1 S58 63.
5. Gorji A, Stemmer N, Rambeck B, Jurgens U, May T, Pannek HW et al. Neocortical microenvironment in patients with intractable epilepsy: potassium and chloride concentrations. Epilepsia 2006 47 : 297 310.
6. Footitt DR, Newberry NR. Cortical spreading depression induces an LTP-like effect in rat neocortex in vitro. Brain Res 1998 781 : 339 42.
7. Gorji A, Zahn PK, Pogatzki EM, Speckmann EJ. Spinal and cortical spreading depression enhance spinal cord activity. Neurobiol Dis 2004 15 : 70 9.
8. Shibata K, Osawa M, Iwata M. Pattern reversal visual evoked potentials in classic and common migraine. J Neurol Sci 1997 145 : 177 81.
9. Hadjikhani N, Sanchez Del Rio M, Wu O, Schwartz D, Bakker D, Fischl B et al. Mechanisms of migraine aura revealed by functional MRI in human visual cortex. Proc Natl Acad Sci USA 2001 98 : 4687 92.
10. Bowyer SM, Aurora KS, Moran JE, Tepley N, Welch KM. Magnetoencephalographic fields from patients with spontaneous and induced migraine aura. Ann Neurol 2001 50 : 582 7.
11. McKendrick AM, Badcock DR. Motion processing deficits in migraine. Cephalalgia 2004 24 : 363 72.
12. Welch KM, Barkley GL, Ramadan NM, D'Andrea G. NMR spectroscopic and magnetoencephalographic studies in migraine with aura: support for the spreading depression hypothesis. Pathol Biol (Paris) 1992 40 : 349 54.
13. Aurora SK, Cao Y, Bowyer SM, Welch KM. The occipital cortex is hyperexcitable in migraine: experimental evidence. Headache 1999 39 : 469 76.
14. Mulleners WM, Chronicle EP, Palmer JE, Koehler PJ, Vredeveld JW. Suppression of perception in migraine: evidence for reduced inhibition in the visual cortex. Neurology 2001 56 : 178 83.
15. Kruger H, Luhmann HJ, Heinemann U. Repetitive spreading depression causes selective suppression of GABAergic function. Neuroreport 1996 7 : 2733 6.
16. Kelman L. The place of osmophobia and taste abnormalities in migraine classification: a tertiary care study of 1237 patients. Cephalalgia 2004 24 : 940 6.
17. Woodhouse A, Drummond PD. Mechanisms of increased sensitivity to noise and light in migraine headache. Cephalalgia 1993 13 : 417 21.