Oxidative metabolism of BDE-99 by human liver microsomes: Predominant role of CYP2B6

Toxicological Sciences

Volumn 129, Issue 2, 2012, Pages 280-292

  Erratico, Claudio A ^a   Szeitz, András ^a   Bandiera, Stelvio M ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

BDE 99; Cytochrome P450 enzymes; Human liver microsomes; Hydroxylated BDEs; Oxidative metabolism; Polybrominated diphenyl ethers (PBDEs)

Indexed keywords

2,2',4,4',5 PENTABROMODIPHENYL ETHER; CYTOCHROME P450 2B6; POLYBROMINATED DIPHENYL ETHER; UNCLASSIFIED DRUG;

AEROBIC METABOLISM; ARTICLE; BIOTRANSFORMATION; CONTROLLED STUDY; HUMAN; HUMAN CELL; LIQUID CHROMATOGRAPHY; LIVER MICROSOME; PROTEIN EXPRESSION; TANDEM MASS SPECTROMETRY;

ARYL HYDROCARBON HYDROXYLASES; BIOCATALYSIS; BIOTRANSFORMATION; CHROMATOGRAPHY, LIQUID; HALOGENATED DIPHENYL ETHERS; HUMANS; HYDROXYLATION; KINETICS; MICROSOMES, LIVER; OXIDATION-REDUCTION; OXIDOREDUCTASES, N-DEMETHYLATING; RECOMBINANT PROTEINS; TANDEM MASS SPECTROMETRY;

EID: 84866600187     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfs215     Document Type: Article

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