Biosensor discovery of thyroxine transport disrupting chemicals

Toxicology and Applied Pharmacology

Volumn 232, Issue 1, 2008, Pages 150-160

  Marchesini, Gerardo R ^a   Meimaridou, Anastasia ^a   Haasnoot, Willem ^a   Meulenberg, Eline ^b   Albertus, Faywell ^a   Mizuguchi, Mineyuki ^c   Takeuchi, Makoto ^c   Irth, Hubertus ^d   Murk, Albertinka J ^a  

^a WAGENINGEN UNIVERSITY   (Netherlands)

^b ELTI Support   (Netherlands)

^c UNIVERSITY OF TOYAMA   (Japan)

^d VU UNIVERSITY AMSTERDAM   (Netherlands)

Author keywords

BFR; Endocrine disruptors; Surface plasmon resonance; TBG; Thyroxine binding globulin; Transport protein; Transthyretin; TTR

Indexed keywords

2 FLUORO 4 NITROPHENOL; 2 NITRO 4 (TRIFLUOROMETHYL)PHENOL; 4 OCTYLPHENOL; 4,4' ISOPROPYLIDENEDIPHENOL; ACETIC ACID DERIVATIVE; BEZAFIBRATE; CARBAMAZEPINE; CHLORPYRIFOS; CLOFIBRATE; CLOFIBRIC ACID; DIATRIZOATE; DICLOFENAC; ENDOCRINE DISRUPTOR; FUROSEMIDE; GENISTEIN; IBUPROFEN; MEFENAMIC ACID; PERFLUOROOCTANESULFONIC ACID; PESTICIDE; PHENOL DERIVATIVE; POLYBROMINATED DIPHENYL ETHER; POLYCHLORINATED BIPHENYL; PREALBUMIN; TETRAIODOTHYROACETIC ACID; THYROID HORMONE; THYROXINE; THYROXINE BINDING GLOBULIN; TRIFLUOPERAZINE; TRIFLUOROACETIC ACID; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; BINDING KINETICS; BIOSENSOR; CHEMICAL STRUCTURE; DRUG PROTEIN BINDING; HALOGENATION; HORMONE PROTEIN COMPLEX; HYDROXYLATION; METABOLITE; PROTEIN BINDING; SCREENING; SURFACE PLASMON RESONANCE; THYROID GLAND; THYROID HORMONE BLOOD LEVEL; TOXICITY TESTING;

AUTOMATION; BIOSENSING TECHNIQUES; ENDOCRINE DISRUPTORS; HUMANS; MOLECULAR STRUCTURE; PREALBUMIN; PROTEIN BINDING; RECOMBINANT PROTEINS; REPRODUCIBILITY OF RESULTS; SMALL MOLECULE LIBRARIES; STRUCTURE-ACTIVITY RELATIONSHIP; SURFACE PLASMON RESONANCE; THYROXINE; THYROXINE-BINDING PROTEINS;

VERTEBRATA;

EID: 51849168060     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2008.06.014     Document Type: Article

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