Comparative oxidative metabolism of BDE-47 and BDE-99 by rat hepatic microsomes

Toxicological Sciences

Volumn 123, Issue 1, 2011, Pages 37-47

  Erratico, Claudio A ^a   Moffatt, Sarah C ^a   Bandiera, Stelvio M ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

BDE 47; BDE 99; Cytochrome P450 enzymes; Hepatic microsomes; Hydroxylated metabolites

Indexed keywords

2,2',4,4' TETRABROMODIPHENYL ETHER; 2,2',4,4',5 PENTABROMODIPHENYL ETHER; 3 HYDROXY 2,2',4,4' PENTABROMODIPHENYL ETHER; 4 HYDROXY 2,2',3,4',5 PENTABROMODIPHENYL ETHER; 4' HYDROXY 2,2',4,5' TETRABROMODIPHENYL ETHER; 6' HYDROXY 2,2',4,4',5 PENTABROMODIPHENYL ETHER; CYTOCHROME P450; CYTOCHROME P450 1A1; CYTOCHROME P450 3A1; DEXAMETHASONE; PHENOBARBITAL; POLYBROMINATED DIPHENYL ETHER; UNCLASSIFIED DRUG;

AEROBIC METABOLISM; ANIMAL CELL; ARTICLE; BIOTRANSFORMATION; CONTROLLED STUDY; ENZYME ACTIVITY; HYDROXYLATION; LIQUID CHROMATOGRAPHY; LIVER MICROSOME; MASS SPECTROMETRY; METABOLITE; NONHUMAN; RAT;

ANIMALS; BIOTRANSFORMATION; CYTOCHROME P-450 ENZYME SYSTEM; ENVIRONMENTAL POLLUTANTS; ENZYME INDUCTION; FLAME RETARDANTS; HALOGENATED DIPHENYL ETHERS; MALE; METABOLIC DETOXICATION, PHASE I; MICROSOMES, LIVER; POLYBROMINATED BIPHENYLS; RATS; RATS, LONG-EVANS;

MAMMALIA; RATTUS;

EID: 80052434627     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfr155     Document Type: Article

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