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Volumn 3, Issue 3, 2012, Pages 455-476

Development of a laminar flow bioreactor by computational fluid dynamics

Author keywords

Bioreactor; Computational fluid dynamics; Computer graphic mesh; Fluid flow simulations; Laminar flow

Indexed keywords

BIOCONVERSION; BIOREACTORS; DESIGN; FLOW OF FLUIDS; LAMINAR FLOW; SCAFFOLDS (BIOLOGY); TISSUE;

EID: 84866558810     PISSN: 20402295     EISSN: 20402309     Source Type: Journal    
DOI: 10.1260/2040-2295.3.3.455     Document Type: Article
Times cited : (12)

References (65)
  • 3
    • 0345015415 scopus 로고    scopus 로고
    • Effects of medium perfusion rate on cell-seeded three-dimensional bone constructs in vitro
    • Cartmell SH, Porter BD, Garcia AJ, Guldberg RE. Effects of medium perfusion rate on cell-seeded three-dimensional bone constructs in vitro. Tissue Engineering. 2003, 9(6): 1197-1203.
    • (2003) Tissue Engineering , vol.9 , Issue.6 , pp. 1197-1203
    • Cartmell, S.H.1    Porter, B.D.2    Garcia, A.J.3    Guldberg, R.E.4
  • 5
    • 0036323143 scopus 로고    scopus 로고
    • Formation of three-dimensional cell/polymer constructs for bone tissue engineering in a spinner flask and a rotating wall vessel bioreactor
    • Sikavitsas VI, Bancroft GN, Mikos AG. Formation of three-dimensional cell/polymer constructs for bone tissue engineering in a spinner flask and a rotating wall vessel bioreactor. Journal of Biomedical Materials Research. 2002, 62(1): 136-148.
    • (2002) Journal of Biomedical Materials Research , vol.62 , Issue.1 , pp. 136-148
    • Sikavitsas, V.I.1    Bancroft, G.N.2    Mikos, A.G.3
  • 6
    • 0242407003 scopus 로고    scopus 로고
    • Generation of 3D retina-like structures from a human retinal cell line in a NASA bioreactor
    • Dutt K, Harris-Hooker S, Ellerson D, Layne D, Kumar R, Hunt R. Generation of 3D retina-like structures from a human retinal cell line in a NASA bioreactor. Cell Transplantation. 2003, 12(7): 717-731.
    • (2003) Cell Transplantation , vol.12 , Issue.7 , pp. 717-731
    • Dutt, K.1    Harris-Hooker, S.2    Ellerson, D.3    Layne, D.4    Kumar, R.5    Hunt, R.6
  • 7
    • 0036194567 scopus 로고    scopus 로고
    • Characterization of the osteoblast-like cell phenotype under microgravity conditions in the NASA-approved Rotating Wall Vessel bioreactor (RWV)
    • Rucci N, Migliaccio S, Zani BM, Taranta A, Teti A. Characterization of the osteoblast-like cell phenotype under microgravity conditions in the NASA-approved Rotating Wall Vessel bioreactor (RWV). Journal of Cellular Biochemistry. 2002, 85(1): 167-179.
    • (2002) Journal of Cellular Biochemistry , vol.85 , Issue.1 , pp. 167-179
    • Rucci, N.1    Migliaccio, S.2    Zani, B.M.3    Taranta, A.4    Teti, A.5
  • 8
    • 0033744133 scopus 로고    scopus 로고
    • Numerical model and experimental validation of microcarrier motion in a rotating bioreactor
    • Pollack SR, Meaney DF, Levine EM, Litt M, Johnston ED. Numerical model and experimental validation of microcarrier motion in a rotating bioreactor. Tissue Engineering. 2000, 6(5): 519-530.
    • (2000) Tissue Engineering , vol.6 , Issue.5 , pp. 519-530
    • Pollack, S.R.1    Meaney, D.F.2    Levine, E.M.3    Litt, M.4    Johnston, E.D.5
  • 9
    • 16444371783 scopus 로고    scopus 로고
    • Oxygen transport and cell viability in an annular flow bioreactor: Comparison of laminar Couette and Taylor-vortex flow regimes
    • Curran SJ, Black RA. Oxygen transport and cell viability in an annular flow bioreactor: comparison of laminar Couette and Taylor-vortex flow regimes. Biotechnology and Bioengineering. 2005, 89(7): 766-774.
    • (2005) Biotechnology and Bioengineering , vol.89 , Issue.7 , pp. 766-774
    • Curran, S.J.1    Black, R.A.2
  • 11
    • 34547816696 scopus 로고    scopus 로고
    • Tissue growth in a rotating bioreactor. Part II: Fluid flow and nutrient transport problems
    • Cummings LJ, Waters SL. Tissue growth in a rotating bioreactor. Part II: fluid flow and nutrient transport problems. Mathematical Medicine and Biology: A Journal of the IMA. 2007, 24(2): 169-208.
    • (2007) Mathematical Medicine and Biology: A Journal of the IMA , vol.24 , Issue.2 , pp. 169-208
    • Cummings, L.J.1    Waters, S.L.2
  • 12
    • 36749085402 scopus 로고    scopus 로고
    • A non-contact suspension culture approach to the culture of osteogenic cells derived from a CD49elow subpopulation of human bone marrow-derived cells
    • Baksh D, Zandstra PW, Davies JE. A non-contact suspension culture approach to the culture of osteogenic cells derived from a CD49elow subpopulation of human bone marrow-derived cells. Biotechnology and Bioengineering. 2007, 98(6): 1195-1208.
    • (2007) Biotechnology and Bioengineering , vol.98 , Issue.6 , pp. 1195-1208
    • Baksh, D.1    Zandstra, P.W.2    Davies, J.E.3
  • 13
    • 34548251103 scopus 로고    scopus 로고
    • Location of scaffolds in bioreactors modulates the hydrodynamic environment experienced by engineered tissues
    • Bilgen B, Barabino GA. Location of scaffolds in bioreactors modulates the hydrodynamic environment experienced by engineered tissues. Biotechnology and Bioengineering. 2007, 98(1): 282-294.
    • (2007) Biotechnology and Bioengineering , vol.98 , Issue.1 , pp. 282-294
    • Bilgen, B.1    Barabino, G.A.2
  • 14
    • 44949280176 scopus 로고
    • Fluid-mechanical damage of animal cells in bioreactors
    • Papoutsakis ET. Fluid-mechanical damage of animal cells in bioreactors. Trends in Biotechnology. 1991, 9(12): 427-437.
    • (1991) Trends in Biotechnology , vol.9 , Issue.12 , pp. 427-437
    • Papoutsakis, E.T.1
  • 17
    • 84890151487 scopus 로고    scopus 로고
    • Bioprocess forces and their impact on cell behavior: Implications for bone regeneration therapy
    • Article ID620247: 1-13; doi:10.4061/2011/620247
    • Brindley D, Moorthy K, Lee JH, Mason C, Kim HW, Wall I. Bioprocess forces and their impact on cell behavior: implications for bone regeneration therapy. Journal of Tissue Engineering. 2011, Article ID620247: 1-13; doi:10.4061/2011/620247.
    • (2011) Journal of Tissue Engineering
    • Brindley, D.1    Moorthy, K.2    Lee, J.H.3    Mason, C.4    Kim, H.W.5    Wall, I.6
  • 18
    • 0037345529 scopus 로고    scopus 로고
    • Fluid flow shear stress stimulates human osteoblast proliferation and differentiation through multiple interacting and competing signal transduction pathways
    • Kapur S, Baylink DJ, Lau KH. Fluid flow shear stress stimulates human osteoblast proliferation and differentiation through multiple interacting and competing signal transduction pathways. Bone. 2003, 32(3): 241-251.
    • (2003) Bone , vol.32 , Issue.3 , pp. 241-251
    • Kapur, S.1    Baylink, D.J.2    Lau, K.H.3
  • 20
    • 79960621058 scopus 로고    scopus 로고
    • Bioreactor systems for bone tissue engineering. Tissue Engineering
    • Rauh J, Milan F, Gunther KP, Stiehler M. Bioreactor systems for bone tissue engineering. Tissue Engineering. Part B, Reviews. 2011, 17(4): 263-280.
    • (2011) Part B, Reviews , vol.17 , Issue.4 , pp. 263-280
    • Rauh, J.1    Milan, F.2    Gunther, K.P.3    Stiehler, M.4
  • 21
    • 53149143499 scopus 로고    scopus 로고
    • Computational evaluation of oxygen and shear stress distributions in 3D perfusion culture systems: Macro-scale and micro-structured models
    • Cioffi M, Kuffer J, Strobel S, Dubini G, Martin I, Wendt D. Computational evaluation of oxygen and shear stress distributions in 3D perfusion culture systems: macro-scale and micro-structured models. Journal of Biomechanics. 2008, 41(14): 2918-2925.
    • (2008) Journal of Biomechanics , vol.41 , Issue.14 , pp. 2918-2925
    • Cioffi, M.1    Kuffer, J.2    Strobel, S.3    Dubini, G.4    Martin, I.5    Wendt, D.6
  • 22
    • 77049125102 scopus 로고    scopus 로고
    • Scalable stirred-suspension bioreactor culture of human pluripotent stem cells. Tissue Engineering
    • Kehoe DE, Jing D, Lock LT, Tzanakakis ES. Scalable stirred-suspension bioreactor culture of human pluripotent stem cells. Tissue Engineering. Part A. 2010, 16(2): 405-421.
    • (2010) Part A , vol.16 , Issue.2 , pp. 405-421
    • Kehoe, D.E.1    Jing, D.2    Lock, L.T.3    Tzanakakis, E.S.4
  • 23
    • 84866562953 scopus 로고
    • Airlift Bioreactors
    • D, In: R, Cook (ed.). Springer, Berlin, Heidelberg, New York
    • Christi MY. Airlift Bioreactors. In: R. D. Cook (ed.). Elsevier Applied Biotechnology Series, Springer, Berlin, Heidelberg, New York, 1989: 335-345.
    • (1989) Elsevier Applied Biotechnology Series , pp. 335-345
    • Christi, M.Y.1
  • 24
    • 0037272461 scopus 로고    scopus 로고
    • Continuous plant cell perfusion culture: Bioreactor characterization and secreted enzyme production
    • Su WW, Arias R. Continuous plant cell perfusion culture: bioreactor characterization and secreted enzyme production. Journal of Bioscience and Bioengineering. 2003, 95(1): 13-20.
    • (2003) Journal of Bioscience and Bioengineering , vol.95 , Issue.1 , pp. 13-20
    • Su, W.W.1    Arias, R.2
  • 25
    • 23244433365 scopus 로고    scopus 로고
    • Tissue engineering of human cartilage and osteochondral composites using recirculation bioreactors
    • Mahmoudifar N, Doran PM. Tissue engineering of human cartilage and osteochondral composites using recirculation bioreactors. Biomaterials. 2005, 26(34): 7012-7024.
    • (2005) Biomaterials , vol.26 , Issue.34 , pp. 7012-7024
    • Mahmoudifar, N.1    Doran, P.M.2
  • 26
    • 0035168980 scopus 로고    scopus 로고
    • Effect of bottom clearance on performance of airlift bioreactor in high-density culture of Panax notoginseng cells
    • Hu W, Zhong J. Effect of bottom clearance on performance of airlift bioreactor in high-density culture of Panax notoginseng cells. Journal of Bioscience and Bioengineering. 2001, 92(4): 389-392.
    • (2001) Journal of Bioscience and Bioengineering , vol.92 , Issue.4 , pp. 389-392
    • Hu, W.1    Zhong, J.2
  • 27
    • 73849092565 scopus 로고    scopus 로고
    • Industrial biotechnology: Tools and applications
    • Tang WL, Zhao H. Industrial biotechnology: tools and applications. Biotechnology Journal. 2009, 4(12): 1725-1739.
    • (2009) Biotechnology Journal , vol.4 , Issue.12 , pp. 1725-1739
    • Tang, W.L.1    Zhao, H.2
  • 28
    • 0037937606 scopus 로고    scopus 로고
    • Design of a flow perfusion bioreactor system for bone tissueengineering applications
    • Bancroft GN, Sikavitsas VI, Mikos AG. Design of a flow perfusion bioreactor system for bone tissueengineering applications. Tissue Engineering. 2003, 9(3): 549-554.
    • (2003) Tissue Engineering , vol.9 , Issue.3 , pp. 549-554
    • Bancroft, G.N.1    Sikavitsas, V.I.2    Mikos, A.G.3
  • 29
    • 0001067474 scopus 로고
    • New pore-size parameter characterizing transport in porous media
    • Johnson DL, Koplik J, Schwartz LM. New pore-size parameter characterizing transport in porous media. Physical Review Letters. 1986, 57(20): 2564-2567.
    • (1986) Physical Review Letters , vol.57 , Issue.20 , pp. 2564-2567
    • Johnson, D.L.1    Koplik, J.2    Schwartz, L.M.3
  • 31
    • 0032970822 scopus 로고    scopus 로고
    • Permeability characteristics of novel mydriatic agents using an in vitro cell culture model that utilizes SIRC rabbit corneal cells
    • Goskonda VR, Khan MA, Hutak CM, Reddy IK. Permeability characteristics of novel mydriatic agents using an in vitro cell culture model that utilizes SIRC rabbit corneal cells. Journal of Pharmaceutical Sciences. 1999, 88(2): 180-184.
    • (1999) Journal of Pharmaceutical Sciences , vol.88 , Issue.2 , pp. 180-184
    • Goskonda, V.R.1    Khan, M.A.2    Hutak, C.M.3    Reddy, I.K.4
  • 32
    • 0037326275 scopus 로고    scopus 로고
    • Articular cartilage bioreactors and bioprocesses
    • Darling EM, Athanasiou KA. Articular cartilage bioreactors and bioprocesses. Tissue Engineering. 2003, 9(1): 9-26.
    • (2003) Tissue Engineering , vol.9 , Issue.1 , pp. 9-26
    • Darling, E.M.1    Athanasiou, K.A.2
  • 34
    • 0003410201 scopus 로고
    • Dover Books on Physics and Chemistry, Dover Publication, New York
    • Bear J. Dynamics of Fluids in Porous Media. Dover Books on Physics and Chemistry, Dover Publication, New York, 1988: 5-20.
    • (1988) Dynamics of Fluids in Porous Media , pp. 5-20
    • Bear, J.1
  • 39
    • 0002127397 scopus 로고
    • Fluid Flow through Packed Columns
    • Ergun S. Fluid Flow through Packed Columns. Chemical Engineering Progress. 1952, 48(2): 89-94.
    • (1952) Chemical Engineering Progress , vol.48 , Issue.2 , pp. 89-94
    • Ergun, S.1
  • 40
    • 0016448873 scopus 로고
    • 3rd ed., John Wiley and Sons, Halstedt Press, New York
    • Nagata S. Mixing-principle and applications, 3rd ed., John Wiley and Sons, Halstedt Press, New York, 1975, 138-144.
    • (1975) Mixing-principle and applications , pp. 138-144
    • Nagata, S.1
  • 45
    • 1642563967 scopus 로고    scopus 로고
    • The role of bioreactors in tissue engineering
    • Martin I, Wendt D, Heberer M. The role of bioreactors in tissue engineering. Trends in Biotechnology. 2004, 22(2): 80-86.
    • (2004) Trends in Biotechnology , vol.22 , Issue.2 , pp. 80-86
    • Martin, I.1    Wendt, D.2    Heberer, M.3
  • 48
    • 0023315016 scopus 로고
    • Theory of dynamic permeability and tortuosity in fluid-saturated porous media
    • Johnson DL, Koplik J, Dashen R. Theory of dynamic permeability and tortuosity in fluid-saturated porous media. Journal of Fluid Mechanics. 1987, 176: 379-420.
    • (1987) Journal of Fluid Mechanics , vol.176 , pp. 379-420
    • Johnson, D.L.1    Koplik, J.2    Dashen, R.3
  • 49
    • 77951978888 scopus 로고    scopus 로고
    • Computational modeling of flow-induced shear stresses within 3D salt-leached porous scaffolds imaged via micro-CT
    • Voronov R, Vangordon S, Sikavitsas VI, Papavassiliou DV. Computational modeling of flow-induced shear stresses within 3D salt-leached porous scaffolds imaged via micro-CT. Journal of Biomechanics. 2010, 43(7): 1279-1286.
    • (2010) Journal of Biomechanics , vol.43 , Issue.7 , pp. 1279-1286
    • Voronov, R.1    Vangordon, S.2    Sikavitsas, V.I.3    Papavassiliou, D.V.4
  • 50
    • 32544432849 scopus 로고    scopus 로고
    • Modeling evaluation of the fluid-dynamic microenvironment in tissue-engineered constructs: A micro-CT based model
    • Cioffi M, Boschetti F, Raimondi MT, Dubini G. Modeling evaluation of the fluid-dynamic microenvironment in tissue-engineered constructs: a micro-CT based model. Biotechnology and Bioengineering. 2006, 93(3): 500-510.
    • (2006) Biotechnology and Bioengineering , vol.93 , Issue.3 , pp. 500-510
    • Cioffi, M.1    Boschetti, F.2    Raimondi, M.T.3    Dubini, G.4
  • 51
    • 12344284982 scopus 로고    scopus 로고
    • 3-D computational modeling of media flow through scaffolds in a perfusion bioreactor
    • Porter B, Zauel R, Stockman H, Guldberg R, Fyhrie D. 3-D computational modeling of media flow through scaffolds in a perfusion bioreactor. Journal of Biomechanics. 2005, 38(3): 543-549.
    • (2005) Journal of Biomechanics , vol.38 , Issue.3 , pp. 543-549
    • Porter, B.1    Zauel, R.2    Stockman, H.3    Guldberg, R.4    Fyhrie, D.5
  • 52
    • 33846928754 scopus 로고    scopus 로고
    • Effects of shear stress on 3-D human mesenchymal stem cell construct development in a perfusion bioreactor system: Experiments and hydrodynamic modeling
    • Zhao F, Chella R, Ma T. Effects of shear stress on 3-D human mesenchymal stem cell construct development in a perfusion bioreactor system: Experiments and hydrodynamic modeling. Biotechnology and Bioengineering. 2007, 96(3): 584-595.
    • (2007) Biotechnology and Bioengineering , vol.96 , Issue.3 , pp. 584-595
    • Zhao, F.1    Chella, R.2    Ma, T.3
  • 54
    • 40249089772 scopus 로고    scopus 로고
    • A finite element study of mechanical stimuli in scaffolds for bone tissue engineering
    • Sandino C, Planell JA, Lacroix D. A finite element study of mechanical stimuli in scaffolds for bone tissue engineering. Journal of Biomechanics. 2008, 41(5): 1005-1014.
    • (2008) Journal of Biomechanics , vol.41 , Issue.5 , pp. 1005-1014
    • Sandino, C.1    Planell, J.A.2    Lacroix, D.3
  • 55
    • 23644448920 scopus 로고    scopus 로고
    • Bioreactors for tissue mass culture: Design, characterization, and recent advances
    • Martin Y, Vermette P. Bioreactors for tissue mass culture: design, characterization, and recent advances. Biomaterials. 2005, 26(35): 7481-7503.
    • (2005) Biomaterials , vol.26 , Issue.35 , pp. 7481-7503
    • Martin, Y.1    Vermette, P.2
  • 57
    • 78649859752 scopus 로고    scopus 로고
    • Influence of shear stress in perfusion bioreactor cultures for the development of three-dimensional bone tissue constructs: A review. Tissue Engineering
    • McCoy RJ, O'Brien FJ. Influence of shear stress in perfusion bioreactor cultures for the development of three-dimensional bone tissue constructs: a review. Tissue Engineering. Part B, Reviews. 2010, 16(6): 587-601.
    • (2010) Part B, Reviews , vol.16 , Issue.6 , pp. 587-601
    • McCoy, R.J.1    O'Brien, F.J.2
  • 58
    • 79953814943 scopus 로고    scopus 로고
    • Influences of extracellular matrix properties and flow shear stresses on stem cell shape in a three-dimensional dynamic environment
    • Weyand B, Reimers K. Vogt PM, Influences of extracellular matrix properties and flow shear stresses on stem cell shape in a three-dimensional dynamic environment. Conf Proc IFMBE Proc. 2011, 30: 47-50.
    • (2011) Conf Proc IFMBE Proc , vol.30 , pp. 47-50
    • Weyand, B.1    Reimers, K.2    Vogt, P.M.3
  • 59
    • 0345255089 scopus 로고    scopus 로고
    • Mesh Topology Identification for Mass-Spring Models
    • E, In: R, Ellis, T. M. Peters (eds.). Lecture Notes in Computer Science, Springer, Berlin, Heidelberg, New York
    • Bianchi G, Harders M, Székely G. Mesh Topology Identification for Mass-Spring Models. In: R. E. Ellis, T. M. Peters (eds.). Medical Image Computing and Computer-Assisted Intervention MICCAI 2003. Lecture Notes in Computer Science, Springer, Berlin, Heidelberg, New York, 2003: 50-58.
    • (2003) Medical Image Computing and Computer-Assisted Intervention MICCAI 2003 , pp. 50-58
    • Bianchi, G.1    Harders, M.2    Székely, G.3
  • 63
    • 0018385399 scopus 로고
    • Difference in the Cell proliferation and colony-forming ability of normal human T lymphocytes
    • Smith SD, Sachs L. Difference in the Cell proliferation and colony-forming ability of normal human T lymphocytes. Clinical Immunol Experimental. 1979, 37: 348-351.
    • (1979) Clinical Immunol Experimental , vol.37 , pp. 348-351
    • Smith, S.D.1    Sachs, L.2
  • 64
    • 0019792605 scopus 로고
    • In vitro growth of lymphoma colonies from children with Non-Hodgkin's lymphoma
    • Smith SD, Wood GW, Fried P, Lownan J T. In vitro growth of lymphoma colonies from children with Non-Hodgkin's lymphoma. Cancer. 1981, 48: 2612-2623.
    • (1981) Cancer , vol.48 , pp. 2612-2623
    • Smith, S.D.1    Wood, G.W.2    Fried, P.3    Lownan, J.T.4
  • 65
    • 77951671240 scopus 로고    scopus 로고
    • In vitro ovine articular chondrocyte proliferation: Experiments and modelling
    • Mancuso L, Liuzzo MI, Fadda S, Pisu M, Concas A, Cincotti A, Cao G. In vitro ovine articular chondrocyte proliferation: experiments and modelling. Cell. 2010, 42: 310-320.
    • (2010) Cell , vol.42 , pp. 310-320
    • Mancuso, L.1    Liuzzo, M.I.2    Fadda, S.3    Pisu, M.4    Concas, A.5    Cincotti, A.6    Cao, G.7


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