메뉴 건너뛰기




Volumn 16, Issue 6, 2010, Pages 587-601

Influence of shear stress in perfusion bioreactor cultures for the development of three-dimensional bone tissue constructs: A review

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMICAL STIMULI; BONE GRAFT SUBSTITUTES; BONE REPLACEMENT; BONE TISSUE; BONE TISSUE ENGINEERING; BONE TISSUE SUBSTITUTES; CELLULAR DEFORMATION; COMPRESSION AND TENSION; CULTURE CONDITIONS; FLUID SHEAR STRESS; IN-VITRO; IN-VIVO; INFLUENCE OF SHEAR STRESS; INTERSTITIAL FLUIDS; OSTEOGENIC DIFFERENTIATION; PERFUSION BIOREACTOR; PHYSICAL DEFORMATION; POTENTIAL RISKS;

EID: 78649859752     PISSN: 19373368     EISSN: None     Source Type: Journal    
DOI: 10.1089/ten.teb.2010.0370     Document Type: Article
Times cited : (178)

References (133)
  • 1
    • 0032442281 scopus 로고    scopus 로고
    • Three-dimensional matrices of calcium polyphosphates support bone growth in vitro and in vivo
    • Baksh, D., Davies, J.E., and Kim, S. Three-dimensional matrices of calcium polyphosphates support bone growth in vitro and in vivo. J Mater Sci Mater Med 9, 743, 1998.
    • (1998) J Mater Sci Mater Med , vol.9 , pp. 743
    • Baksh, D.1    Davies, J.E.2    Kim, S.3
  • 2
    • 33847661541 scopus 로고    scopus 로고
    • Assessment of bone ingrowth into porous biomaterials using MICRO-CT
    • Jones, A.C., Arns, C.H., Sheppard, A.P., et al. Assessment of bone ingrowth into porous biomaterials using MICRO-CT. Biomaterials 28, 2491, 2007.
    • (2007) Biomaterials , vol.28 , pp. 2491
    • Jones, A.C.1    Arns, C.H.2    Sheppard, A.P.3
  • 3
    • 0034425983 scopus 로고    scopus 로고
    • Tissue-engineered bone regeneration
    • Petite, H., Viateau, V., Bensaid, W., et al. Tissue-engineered bone regeneration. Nat Biotech 18, 959, 2000.
    • (2000) Nat Biotech , vol.18 , pp. 959
    • Petite, H.1    Viateau, V.2    Bensaid, W.3
  • 4
    • 33646553866 scopus 로고    scopus 로고
    • In vitro ossification and remodeling of mineralized collagen i scaffolds
    • Domaschke, H., Gelinsky, M., Burmeister, B., et al. In vitro ossification and remodeling of mineralized collagen I scaffolds. Tissue Eng 12, 949, 2006.
    • (2006) Tissue Eng , vol.12 , pp. 949
    • Domaschke, H.1    Gelinsky, M.2    Burmeister, B.3
  • 5
    • 56049090565 scopus 로고    scopus 로고
    • Microarchitecture of three-dimensional scaffolds influences cell migration behavior via junction interactions
    • Harley, B.A., Kim, H., Zaman, M.H., et al. Microarchitecture of three-dimensional scaffolds influences cell migration behavior via junction interactions. Biophys J 95, 4013, 2008.
    • (2008) Biophys J , vol.95 , pp. 4013
    • Harley, B.A.1    Kim, H.2    Zaman, M.H.3
  • 6
    • 77951975692 scopus 로고    scopus 로고
    • Cell contraction forces in scaffolds with varying pore size and cell density
    • Corin, K.A., and Gibson, L.J. Cell contraction forces in scaffolds with varying pore size and cell density. Bioma-terials 31, 4835, 2010.
    • (2010) Bioma-terials , vol.31 , pp. 4835
    • Corin, K.A.1    Gibson, L.J.2
  • 7
    • 77952932509 scopus 로고    scopus 로고
    • Engineering tumors: A tissue engineering perspective in cancer biology
    • Burdett, E., Kasper, F.K., Mikos, A.G., and Ludwig, J.A. Engineering tumors: a tissue engineering perspective in cancer biology. Tissue Eng Part B Rev 16, 351, 2010.
    • (2010) Tissue Eng Part B Rev , vol.16 , pp. 351
    • Burdett, E.1    Kasper, F.K.2    Mikos, A.G.3    Ludwig, J.A.4
  • 8
    • 35948949806 scopus 로고    scopus 로고
    • Tissue-engineered bone serves as a target for metastasis of human breast cancer in a mouse model
    • Moreau, J.E., Anderson, K., Mauney, J.R., et al. Tissue-engineered bone serves as a target for metastasis of human breast cancer in a mouse model. Cancer Res 67, 10304, 2007.
    • (2007) Cancer Res , vol.67 , pp. 10304
    • Moreau, J.E.1    Anderson, K.2    Mauney, J.R.3
  • 9
    • 77953467681 scopus 로고    scopus 로고
    • A novel collagen scaffold supports human osteogenesis-applications for bone tissue engineering
    • Keogh, M., O' Brien, F., and Daly, J. A novel collagen scaffold supports human osteogenesis-applications for bone tissue engineering. Cell Tissue Res 340, 169, 2010.
    • (2010) Cell Tissue Res , vol.340 , pp. 169
    • Keogh, M.1    Brien F, O.'.2    Daly, J.3
  • 10
    • 33947516487 scopus 로고    scopus 로고
    • A comparison of the osteogenic potential of adult rat mesenchymal stem cells cultured in 2-D and on 3-D collagen glycosaminoglycan scaffolds
    • Farrell, E., Byrne, E., Fischer, J., et al. A comparison of the osteogenic potential of adult rat mesenchymal stem cells cultured in 2-D and on 3-D collagen glycosaminoglycan scaffolds. Technol Health Care 15, 19, 2007.
    • (2007) Technol Health Care , vol.15 , pp. 19
    • Farrell, E.1    Byrne, E.2    Fischer, J.3
  • 11
    • 33646375175 scopus 로고    scopus 로고
    • A collagen-glycosaminoglycan scaffold supports adult rat mesen-chymal stem cell differentiation along osteogenic and chondrogenic routes
    • Farrell, E., O'Brien, F.J., Doyle, P., et al. A collagen- glycosaminoglycan scaffold supports adult rat mesen-chymal stem cell differentiation along osteogenic and chondrogenic routes. Tissue Eng 12, 459, 2006.
    • (2006) Tissue Eng , vol.12 , pp. 459
    • Farrell, E.1    O'Brien, F.J.2    Doyle, P.3
  • 12
    • 33644843422 scopus 로고    scopus 로고
    • The in vitro growth and activity of sheep osteoblasts on three-dimensional scaffolds from poly(L/DL-lactide) 80/20%
    • Gugala, Z., and Gogolewski, S. The in vitro growth and activity of sheep osteoblasts on three-dimensional scaffolds from poly(L/DL-lactide) 80/20%. J Biomed Mater Res Part A 75A, 702, 2005.
    • (2005) J Biomed Mater Res Part A , vol.75 A , pp. 702
    • Gugala, Z.1    Gogolewski, S.2
  • 13
    • 0032144180 scopus 로고    scopus 로고
    • Three-dimensional culture of rat calvarial osteoblasts in porous biodegradable polymers
    • Ishaug-Riley, S.L., Crane-Kruger, G.M., Yaszemski, M.J., and Mikos, A.G. Three-dimensional culture of rat calvarial osteoblasts in porous biodegradable polymers. Biomater-ials 19, 1405, 1998.
    • (1998) Biomater-ials , vol.19 , pp. 1405
    • Ishaug-Riley, S.L.1    Crane-Kruger, G.M.2    Yaszemski, M.J.3    Mikos, A.G.4
  • 14
    • 13444273280 scopus 로고    scopus 로고
    • Influence of macroporous protein scaffolds on bone tissue engineering from bone marrow stem cells
    • Kim, H.J., Kim, U., Vunjak-Novakovic, G., Min, B., and Kaplan, D.L. Influence of macroporous protein scaffolds on bone tissue engineering from bone marrow stem cells. Biomaterials 26, 4442, 2005.
    • (2005) Biomaterials , vol.26 , pp. 4442
    • Kim, H.J.1    Kim, U.2    Vunjak-Novakovic, G.3    Min, B.4    Kaplan, D.L.5
  • 15
    • 23644441508 scopus 로고    scopus 로고
    • Three-dimensional growth of differentiating MC3T3-E1 pre-osteoblasts on porous titanium scaffolds
    • St. Pierre, J., Gauthier, M., Lefebvre, L., and Tabrizian, M. Three-dimensional growth of differentiating MC3T3-E1 pre-osteoblasts on porous titanium scaffolds. Biomaterials 26, 7319, 2005.
    • (2005) Biomaterials , vol.26 , pp. 7319
    • St. Pierre, J.1    Gauthier, M.2    Lefebvre, L.3    Tabrizian, M.4
  • 16
    • 70349113961 scopus 로고    scopus 로고
    • Osteoblast activity on collagen-GAG scaffolds is affected by collagen and GAG concentrations
    • Tierney, C.M., Jaasma, M.J., and O'Brien, F.J. Osteoblast activity on collagen-GAG scaffolds is affected by collagen and GAG concentrations. J Biomed Mater Res Part A 91A, 92, 2009.
    • (2009) J Biomed Mater Res Part A , vol.91 A , pp. 92
    • Tierney, C.M.1    Jaasma, M.J.2    O'Brien, F.J.3
  • 17
    • 0036246273 scopus 로고    scopus 로고
    • Effects of bio-mechanical stress on bones in animals
    • Burr, D.B., Robling, A.G., and Turner, C.H. Effects of bio-mechanical stress on bones in animals. Bone 30, 781, 2002.
    • (2002) Bone , vol.30 , pp. 781
    • Burr, D.B.1    Robling, A.G.2    Turner, C.H.3
  • 18
    • 0028024121 scopus 로고
    • Mechanotrans-duction in bone: Do bone cells act as sensors of fluid flow?
    • Turner, C., Forwood, M., and Otter, M. Mechanotrans-duction in bone: do bone cells act as sensors of fluid flow? FASEB J 8, 875, 1994.
    • (1994) FASEB J , vol.8 , pp. 875
    • Turner, C.1    Forwood, M.2    Otter, M.3
  • 19
  • 20
    • 0018076154 scopus 로고
    • Inhibition of bone formation during space flight
    • Morey, E., and Baylink, D. Inhibition of bone formation during space flight. Science 201, 1138, 1978.
    • (1978) Science , vol.201 , pp. 1138
    • Morey, E.1    Baylink, D.2
  • 21
    • 0031718368 scopus 로고    scopus 로고
    • The effects of twelve weeks of bed rest on bone histology, biochemical markers ofbone turnover, and calcium homeostasis in eleven normal subjects
    • Zerwekh, J.E., Ruml, L.A., Gottschalk, F., and Pak, C.Y.C. The effects of twelve weeks of bed rest on bone histology, biochemical markers ofbone turnover, and calcium homeostasis in eleven normal subjects. J Bone Miner Res 13, 1594, 1998.
    • (1998) J Bone Miner Res , vol.13 , pp. 1594
    • Zerwekh, J.E.1    Ruml, L.A.2    Gottschalk, F.3    Pak, C.Y.C.4
  • 22
    • 0029985585 scopus 로고    scopus 로고
    • In vivo measurement of human tibial strains during vigorous activity
    • Burr, D.B., Milgrom, C., Fyhrie, D., et al. In vivo measurement of human tibial strains during vigorous activity. Bone 18, 405, 1996.
    • (1996) Bone , vol.18 , pp. 405
    • Burr, D.B.1    Milgrom, C.2    Fyhrie, D.3
  • 23
    • 0028807366 scopus 로고
    • Mechanotransduction and the functional response of bone to mechanical strain
    • Duncan, R.L., and Turner, C.H. Mechanotransduction and the functional response of bone to mechanical strain. Calcif Tissue Int 57, 344, 1995.
    • (1995) Calcif Tissue Int , vol.57 , pp. 344
    • Duncan, R.L.1    Turner, C.H.2
  • 24
    • 32844469818 scopus 로고    scopus 로고
    • Evaluation of endothelial cell adherence onto collagen and fibronectin: A comparison between jet impingement and flow chamber techniques
    • Bouafsoun, A., Othmane, A., Kerkeni, A., Jaffrézic, N., and Ponsonnet, L. Evaluation of endothelial cell adherence onto collagen and fibronectin: a comparison between jet impingement and flow chamber techniques. Mater Sci Eng C 26, 260, 2006.
    • (2006) Mater Sci Eng C , vol.26 , pp. 260
    • Bouafsoun, A.1    Othmane, A.2    Kerkeni, A.3    Jaffrézic, N.4    Ponsonnet, L.5
  • 25
    • 0032505720 scopus 로고    scopus 로고
    • Cellular and cytoskeleton morphology and strength of adhesion of cells on self-assembled monolayers of organosilanes
    • Kapur, R., and Rudolph, A.S. Cellular and cytoskeleton morphology and strength of adhesion of cells on self-assembled monolayers of organosilanes. Exp Cell Res 244, 275, 1998.
    • (1998) Exp Cell Res , vol.244 , pp. 275
    • Kapur, R.1    Rudolph, A.S.2
  • 26
    • 0025500271 scopus 로고
    • The effect of fluid shear stress upon cell adhesion to fibronectin-treated surfaces
    • Truskey, G.A., and Pirone, J.S. The effect of fluid shear stress upon cell adhesion to fibronectin-treated surfaces. J Biomed Mater Res 24, 1333, 1990.
    • (1990) J Biomed Mater Res , vol.24 , pp. 1333
    • Truskey, G.A.1    Pirone, J.S.2
  • 27
    • 0027571722 scopus 로고
    • Relationship between 3T3 cell spreading and the strength of adhesion on glass and silane surfaces
    • Truskey, G.A., and Proulx, T.L. Relationship between 3T3 cell spreading and the strength of adhesion on glass and silane surfaces. Biomaterials 14, 243, 1993.
    • (1993) Biomaterials , vol.14 , pp. 243
    • Truskey, G.A.1    Proulx, T.L.2
  • 28
    • 0026447693 scopus 로고
    • Influence of substratum wettability on the strength of adhesion of human fibroblasts
    • Van Kooten, T., Schakenraad, J., Van Der Mei, H., and Bus-scher, H. Influence of substratum wettability on the strength of adhesion of human fibroblasts. Biomaterials 13, 897, 1992.
    • (1992) Biomaterials , vol.13 , pp. 897
    • Van Kooten, T.1    Schakenraad, J.2    Van Der Mei, H.3    Bus-Scher, H.4
  • 29
    • 0027943432 scopus 로고
    • Fluid shear induced endothelial cell detachment from glass-influence of adhesion time and shear stress
    • Van Kooten, T., Schakenraad, J., Van Der Mei, H., et al. Fluid shear induced endothelial cell detachment from glass-influence of adhesion time and shear stress. Med Eng Phys 16, 506, 1994.
    • (1994) Med Eng Phys , vol.16 , pp. 506
    • Van Kooten, T.1    Schakenraad, J.2    Van Der Mei, H.3
  • 30
    • 0038799870 scopus 로고    scopus 로고
    • Cell adhesion on gaseous plasma modified poly-(-lactide) surface under shear stress field
    • Wan, Y., Yang, J., Yang, J., Bei, J., and Wang, S. Cell adhesion on gaseous plasma modified poly-(-lactide) surface under shear stress field. Biomaterials 24, 3757, 2003.
    • (2003) Biomaterials , vol.24 , pp. 3757
    • Wan, Y.1    Yang, J.2    Yang, J.3    Bei, J.4    Wang, S.5
  • 31
    • 2342433916 scopus 로고    scopus 로고
    • Characterization of surface property of poly(lactide-co-glycolide) after oxygen plasma treatment
    • Wan, Y., Qu, X., Lu, J., et al. Characterization of surface property of poly(lactide-co-glycolide) after oxygen plasma treatment. Biomaterials 25, 4777, 2004.
    • (2004) Biomaterials , vol.25 , pp. 4777
    • Wan, Y.1    Qu, X.2    Lu, J.3
  • 32
    • 0029958627 scopus 로고    scopus 로고
    • Effect of receptor-ligand affinity on the strength of endothelial cell adhesion
    • Xiao, Y., and Truskey, G. Effect of receptor-ligand affinity on the strength of endothelial cell adhesion. Biophys J 71, 2869, 1996.
    • (1996) Biophys J , vol.71 , pp. 2869
    • Xiao, Y.1    Truskey, G.2
  • 33
    • 0035239029 scopus 로고    scopus 로고
    • Effect of surface roughness of hydroxyapatite on human bone marrow cell adhesion, proliferation, differentiation and detachment strength
    • Deligianni, D.D., Katsala, N.D., Koutsoukos, P.G., and Missirlis, Y.F. Effect of surface roughness of hydroxyapatite on human bone marrow cell adhesion, proliferation, differentiation and detachment strength. Biomaterials 22, 87, 2001.
    • (2001) Biomaterials , vol.22 , pp. 87
    • Deligianni, D.D.1    Katsala, N.D.2    Koutsoukos, P.G.3    Missirlis, Y.F.4
  • 34
    • 67649922824 scopus 로고    scopus 로고
    • A novel mode of cell detachment from fibrillar fibronectin matrix under shear
    • Engler, A.J., Chan, M., Boettiger, D., and Schwarzbauer, J.E. A novel mode of cell detachment from fibrillar fibronectin matrix unDer shear. J Cell Sci 122, 1647, 2009.
    • (2009) J Cell Sci , vol.122 , pp. 1647
    • Engler, A.J.1    Chan, M.2    Boettiger, D.3    Schwarzbauer, J.E.4
  • 35
    • 0031215026 scopus 로고    scopus 로고
    • Quantification of cell adhesion using a spinning disc device and application to surface-reactive materials
    • Garća, A.J., Ducheyne, P., and Boettiger, D. Quantification of cell adhesion using a spinning disc device and application to surface-reactive materials. Biomaterials 18, 1091, 1997.
    • (1997) Biomaterials , vol.18 , pp. 1091
    • Garća, A.J.1    Ducheyne, P.2    Boettiger, D.3
  • 36
    • 0030912681 scopus 로고    scopus 로고
    • Cell adhesion strength increases linearly with adsorbed fibronectin surface density
    • Garcia, A.J., Ducheyne, P., and Boettiger, D. Cell adhesion strength increases linearly with adsorbed fibronectin surface density. Tissue Eng 3, 197, 1997.
    • (1997) Tissue Eng , vol.3 , pp. 197
    • Garcia, A.J.1    Ducheyne, P.2    Boettiger, D.3
  • 37
    • 0024017405 scopus 로고
    • Cell adhesion to a series of hydrophilic-hydrophobic copolymers studies with a spinning disc apparatus
    • Horbett, T.A., Waldburger, J.J., Ratner, B.D., and Hoffman, A.S. Cell adhesion to a series of hydrophilic-hydrophobic copolymers studies with a spinning disc apparatus. J Biomed Mater Res 22, 383, 1988.
    • (1988) J Biomed Mater Res , vol.22 , pp. 383
    • Horbett, T.A.1    Waldburger, J.J.2    Ratner, B.D.3    Hoffman, A.S.4
  • 38
    • 0343554638 scopus 로고    scopus 로고
    • Application of fluid mechanic and kinetic models to characterize mammalian cell detachment in a radial-flowchamber
    • Goldstein, A.S., and DiMilla, P.A. Application of fluid mechanic and kinetic models to characterize mammalian cell detachment in a radial-flow chamber. Biotechnol Bioeng 55, 616, 1997.
    • (1997) Biotechnol Bioeng , vol.55 , pp. 616
    • Goldstein, A.S.1    Dimilla, P.A.2
  • 39
    • 0348014793 scopus 로고    scopus 로고
    • Examination of membrane rupture as a mechanism for mammalian cell detachment from fibronectin-coated biomaterials
    • Goldstein, A.S., and DiMilla, P.A. Examination of membrane rupture as a mechanism for mammalian cell detachment from fibronectin-coated biomaterials. J Biomed Mater Res Part A 67A, 658, 2003.
    • (2003) J Biomed Mater Res Part A , vol.67 A , pp. 658
    • Goldstein, A.S.1    Dimilla, P.A.2
  • 40
    • 0035504141 scopus 로고    scopus 로고
    • Quantitative analysis of cell detachment by shear stress
    • Furukawa, K.S., Ushida, T., Nagase, T., et al. Quantitative analysis of cell detachment by shear stress. Mater Sci Eng C 17, 55, 2001.
    • (2001) Mater Sci Eng C , vol.17 , pp. 55
    • Furukawa, K.S.1    Ushida, T.2    Nagase, T.3
  • 41
    • 77951487181 scopus 로고    scopus 로고
    • Quantification of the adhesion strength of fibroblast cells on ethylene glycol terminated self-assembled monolayers by a micro-fluidic shear force assay
    • Christophis, C., Grunze, M., and Rosenhahn, A. Quantification of the adhesion strength of fibroblast cells on ethylene glycol terminated self-assembled monolayers by a micro-fluidic shear force assay. Phys Chem Chem Phys 12, 4498, 2010.
    • (2010) Phys Chem Chem Phys , vol.12 , pp. 4498
    • Christophis, C.1    Grunze, M.2    Rosenhahn, A.3
  • 42
    • 4544288097 scopus 로고    scopus 로고
    • Microfluidic shear devices for quantitative analysis of cell adhesion
    • Lu, H., Koo, L.Y., Wang, W.M., et al. Microfluidic shear devices for quantitative analysis of cell adhesion. Anal Chem 76, 5257, 2004.
    • (2004) Anal Chem , vol.76 , pp. 5257
    • Lu, H.1    Koo, L.Y.2    Wang, W.M.3
  • 43
    • 0036791972 scopus 로고    scopus 로고
    • Fluid flow increases mineralized matrix deposition in 3D perfusion culture of marrow stromal osteoblasts in a dose-dependent manner
    • Bancroft, G.N., Sikavitsas, V.I., Van den Dolder, J., et al. Fluid flow increases mineralized matrix deposition in 3D perfusion culture of marrow stromal osteoblasts in a dose-dependent manner. Proc Natl Acad Sci USA 99, 12600, 2002.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 12600
    • Bancroft, G.N.1    Sikavitsas, V.I.2    Van Den Dolder, J.3
  • 44
    • 0035372005 scopus 로고    scopus 로고
    • Effect of convection on osteoblastic cell growth and function in biodegradable polymer foam scaffolds
    • Goldstein, A.S., Juarez, T.M., Helmke, C.D., Gustin, M.C., and Mikos, A.G. Effect of convection on osteoblastic cell growth and function in biodegradable polymer foam scaffolds. Biomaterials 22, 1279, 2001.
    • (2001) Biomaterials , vol.22 , pp. 1279
    • Goldstein, A.S.1    Juarez, T.M.2    Helmke, C.D.3    Gustin, M.C.4    Mikos, A.G.5
  • 45
    • 0031195238 scopus 로고    scopus 로고
    • Bone formation by three-dimensional stromal osteoblast culture in biodegradable polymer scaffolds
    • Ishaug, S.L., Crane, G.M., Miller, M.J., et al. Bone formation by three-dimensional stromal osteoblast culture in biodegradable polymer scaffolds. J Biomed Mater Res 36, 17, 1997.
    • (1997) J Biomed Mater Res , vol.36 , pp. 17
    • Ishaug, S.L.1    Crane, G.M.2    Miller, M.J.3
  • 46
    • 0033196805 scopus 로고    scopus 로고
    • Method for quantitative analysis of glycosaminoglycan distribution in cultured natural and engineered cartilage
    • Martin, I., Obradovic, B., Freed, L.E., and Vunjak-Novakovic, G. Method for quantitative analysis of glycosaminoglycan distribution in cultured natural and engineered cartilage. Ann Biomed Eng 27, 656, 1999.
    • (1999) Ann Biomed Eng , vol.27 , pp. 656
    • Martin, I.1    Obradovic, B.2    Freed, L.E.3    Vunjak-Novakovic, G.4
  • 47
    • 1642563967 scopus 로고    scopus 로고
    • The role of bio-reactors in tissue engineering
    • Martin, I., Wendt, D., and Heberer, M. The role of bio-reactors in tissue engineering. Trends Biotechnol 22, 80, 2004.
    • (2004) Trends Biotechnol , vol.22 , pp. 80
    • Martin, I.1    Wendt, D.2    Heberer, M.3
  • 48
    • 77949408476 scopus 로고    scopus 로고
    • A multichamber fluidic device for 3D cultures under interstitial flow with live imaging: Development, characterization, and applications
    • Bonvin, C., Overney, J., Shieh, A.C., Dixon, J.B., and Swartz, M.A. A multichamber fluidic device for 3D cultures unDer interstitial flow with live imaging: development, characterization, and applications. Biotechnol Bioeng 105, 982, 2010.
    • (2010) Biotechnol Bioeng , vol.105 , pp. 982
    • Bonvin, C.1    Overney, J.2    Shieh, A.C.3    Dixon, J.B.4    Swartz, M.A.5
  • 49
    • 38749097368 scopus 로고    scopus 로고
    • Design and validation of a dynamic flow perfusion bioreactor for use with compliant tissue engineering scaffolds
    • Jaasma, M.J., Plunkett, N.A., and O'Brien, F.J. Design and validation of a dynamic flow perfusion bioreactor for use with compliant tissue engineering scaffolds. J Biotechnol 133, 490, 2008.
    • (2008) J Biotechnol , vol.133 , pp. 490
    • Jaasma, M.J.1    Plunkett, N.A.2    O'Brien, F.J.3
  • 50
    • 23244452726 scopus 로고    scopus 로고
    • Perfusion bioreactor system for human mesenchymal stem cell tissue engineering: Dynamic cell seeding and construct development
    • Zhao, F., and Ma, T. Perfusion bioreactor system for human mesenchymal stem cell tissue engineering: dynamic cell seeding and construct development. Biotechnol Bioeng 91, 482, 2005.
    • (2005) Biotechnol Bioeng , vol.91 , pp. 482
    • Zhao, F.1    Ma, T.2
  • 51
    • 31844456756 scopus 로고    scopus 로고
    • Bioreactor-based engineering of osteochondral grafts: From model systems to tissue manufacturing
    • Wendt, D., Jakob, M., and Martin, I. Bioreactor-based engineering of osteochondral grafts: from model systems to tissue manufacturing. J Biosci Bioeng 100, 489, 2005.
    • (2005) J Biosci Bioeng , vol.100 , pp. 489
    • Wendt, D.1    Jakob, M.2    Martin, I.3
  • 52
    • 33847644129 scopus 로고    scopus 로고
    • Noninvasive image analysis of 3D construct mineralization in a perfusion bioreactor
    • Porter, B.D., Lin, A.S., Peister, A., Hutmacher, D., and Guldberg, R.E. Noninvasive image analysis of 3D construct mineralization in a perfusion bioreactor. Biomaterials 28, 2525, 2007.
    • (2007) Biomaterials , vol.28 , pp. 2525
    • Porter, B.D.1    Lin, A.S.2    Peister, A.3    Hutmacher, D.4    Guldberg, R.E.5
  • 53
    • 0001031272 scopus 로고
    • Synthesis and characterization of a model extracellular matrix that induces partial regeneration of adult mammalian skin
    • Yannas, I.V., Lee, E., Orgill, D.P., Skrabut, E.M., and Murphy, G.F. Synthesis and characterization of a model extracellular matrix that induces partial regeneration of adult mammalian skin. Proc Natl Acad Sci USA 86, 933, 1989.
    • (1989) Proc Natl Acad Sci USA , vol.86 , pp. 933
    • Yannas, I.V.1    Lee, E.2    Orgill, D.P.3    Skrabut, E.M.4    Murphy, G.F.5
  • 54
    • 59349093880 scopus 로고    scopus 로고
    • Influence of a novel calcium-phosphate coating on the mechanical properties of highly porous collagen scaffolds for bone repair
    • Al-Munajjed, A.A., and O'Brien, F.J. Influence of a novel calcium-phosphate coating on the mechanical properties of highly porous collagen scaffolds for bone repair. J Mech Behav Biomed Mater 2, 138, 2009.
    • (2009) J Mech Behav Biomed Mater , vol.2 , pp. 138
    • Al-Munajjed, A.A.1    O'Brien, F.J.2
  • 55
    • 67749142428 scopus 로고    scopus 로고
    • Development of a biomimetic collagen-hydroxyapatite scaffold for bone tissue engineering using a SBF immersion technique
    • Al-Munajjed, A.A., Plunkett, N.A., Gleeson, J.P., et al. Development of a biomimetic collagen-hydroxyapatite scaffold for bone tissue engineering using a SBF immersion technique. J Biomed Mater Res Part B Appl Biomater 90B, 584, 2009.
    • (2009) J Biomed Mater Res Part B Appl Biomater , vol.90 B , Issue.584
    • Al-Munajjed, A.A.1    Plunkett, N.A.2    Gleeson, J.P.3
  • 56
    • 78649874333 scopus 로고    scopus 로고
    • Development and characterisation of a collagen nano-hydroxyapatite composite scaffold for bone tissue engineering
    • Cunniffe, G., Dickson, G., Partap, S., Stanton, K., and O'Brien, F. Development and characterisation of a collagen nano-hydroxyapatite composite scaffold for bone tissue engineering. J Mater Sci Mater Med 21, 2293, 2010.
    • (2010) J Mater Sci Mater Med , vol.21 , pp. 2293
    • Cunniffe, G.1    Dickson, G.2    Partap, S.3    Stanton, K.4    O'Brien, F.5
  • 57
    • 0242438580 scopus 로고    scopus 로고
    • Influence of freezing rate on pore structure in freeze-dried collagen-GAG scaffolds
    • O'Brien, F.J., Harley, B.A., Yannas, I.V., and Gibson, L. Influence of freezing rate on pore structure in freeze-dried collagen-GAG scaffolds. Biomaterials 25, 1077, 2004.
    • (2004) Biomaterials , vol.25 , pp. 1077
    • O'Brien, F.J.1    Harley, B.A.2    Yannas, I.V.3    Gibson, L.4
  • 58
    • 56049098528 scopus 로고    scopus 로고
    • Non-bioengineered silk fibroin protein 3D scaffolds for potential biotechnological and tissue engineering applications
    • Mandal, B.B., and Kundu, S.C. Non-bioengineered silk fibroin protein 3D scaffolds for potential biotechnological and tissue engineering applications. Macromol Biosci 8, 807, 2008.
    • (2008) Macromol Biosci , vol.8 , pp. 807
    • Mandal, B.B.1    Kundu, S.C.2
  • 59
    • 29744456039 scopus 로고    scopus 로고
    • Prediction of the micro-fluid dynamic environment imposed to three-dimensional engineered cell systems in bioreactors
    • Boschetti, F., Raimondi, M.T., Migliavacca, F., and Dubini, G. Prediction of the micro-fluid dynamic environment imposed to three-dimensional engineered cell systems in bioreactors. J Biomech 39, 418, 2006.
    • (2006) J Biomech , vol.39 , pp. 418
    • Boschetti, F.1    Raimondi, M.T.2    Migliavacca, F.3    Dubini, G.4
  • 60
    • 66249112862 scopus 로고    scopus 로고
    • A comparative study of shear stresses in collagen-glycosaminoglycan and calcium phosphate scaffolds in bone tissue-engineering bioreactors
    • Jungreuthmayer, C., Donahue, S.W., Jaasma, M.J., et al. A comparative study of shear stresses in collagen-glycosaminoglycan and calcium phosphate scaffolds in bone tissue-engineering bioreactors. Tissue Eng Part A 15, 1141, 2009.
    • (2009) Tissue Eng Part A , vol.15 , pp. 1141
    • Jungreuthmayer, C.1    Donahue, S.W.2    Jaasma, M.J.3
  • 61
    • 12344284982 scopus 로고    scopus 로고
    • 3-D computational modeling of media flow through scaffolds in a perfusion bioreactor
    • Porter, B., Zauel, R., Stockman, H., Guldberg, R., and Fyhrie, D. 3-D computational modeling of media flow through scaffolds in a perfusion bioreactor. J Biomech 38, 543, 2005.
    • (2005) J Biomech , vol.38 , pp. 543
    • Porter, B.1    Zauel, R.2    Stockman, H.3    Guldberg, R.4    Fyhrie, D.5
  • 62
    • 3042782581 scopus 로고    scopus 로고
    • Scaffold-based tissue engineering: Rationale for computer-aided design and solid free-form fabrication systems
    • Hutmacher, D.W., Sittinger, M., and Risbud, M.V. Scaffold-based tissue engineering: rationale for computer-aided design and solid free-form fabrication systems. Trends Biotechnol 22, 354, 2004.
    • (2004) Trends Biotechnol , vol.22 , pp. 354
    • Hutmacher, D.W.1    Sittinger, M.2    Risbud, M.V.3
  • 63
    • 21844438003 scopus 로고    scopus 로고
    • Porous scaffold design for tissue engineering
    • Hollister, S.J. Porous scaffold design for tissue engineering. Nat Mater 4, 518, 2005.
    • (2005) Nat Mater , vol.4 , pp. 518
    • Hollister, S.J.1
  • 64
    • 3242700527 scopus 로고    scopus 로고
    • Making tissue engineering scaffolds work. Review: The application of solid freeform fabrication technology to the production of tissue engineering scaffolds
    • Sachlos, E., and Czernuszka, J.T. Making tissue engineering scaffolds work. Review: the application of solid freeform fabrication technology to the production of tissue engineering scaffolds. Eur Cell Mater 5, 29, 2003.
    • (2003) Eur Cell Mater , vol.5 , pp. 29
    • Sachlos, E.1    Czernuszka, J.T.2
  • 65
    • 42449159656 scopus 로고    scopus 로고
    • A review of rapid prototyping techniques for tissue engineering purposes
    • Peltola, S.M., Melchels, F.P.W., Grijpma, D.W., and Kello-mäki, M. A review of rapid prototyping techniques for tissue engineering purposes. Ann Med 40, 268, 2008.
    • (2008) Ann Med , vol.40 , pp. 268
    • Peltola, S.M.1    Melchels, F.P.W.2    Grijpma, D.W.3    Kello-Mäki, M.4
  • 67
    • 67651154456 scopus 로고    scopus 로고
    • Cell mechanics: Dissecting the physical responses of cells to force
    • Hoffman, B.D., and Crocker, J.C. Cell mechanics: dissecting the physical responses of cells to force. Annu Rev Biomed Eng 11, 259, 2009.
    • (2009) Annu Rev Biomed Eng , vol.11 , pp. 259
    • Hoffman, B.D.1    Crocker, J.C.2
  • 68
    • 35348847063 scopus 로고    scopus 로고
    • Cell mechanics: Integrating cell responses to mechanical stimuli
    • Janmey, P.A., and McCulloch, C.A. Cell mechanics: integrating cell responses to mechanical stimuli. Annu Rev Biomed Eng 9, 1, 2007.
    • (2007) Annu Rev Biomed Eng , vol.9 , pp. 1
    • Janmey, P.A.1    McCulloch, C.A.2
  • 69
    • 0034254009 scopus 로고    scopus 로고
    • The collagen receptor integrins have distinct ligand recognition and signaling functions
    • Heino, J. The collagen receptor integrins have distinct ligand recognition and signaling functions. Matrix Biol 19, 319, 2000.
    • (2000) Matrix Biol , vol.19 , pp. 319
    • Heino, J.1
  • 70
    • 64849094619 scopus 로고    scopus 로고
    • Mechanically induced osteogenic differentiation-the role of RhoA, ROCKII and cytoskeletal dynamics
    • Arnsdorf, E.J., Tummala, P., Kwon, R.Y., and Jacobs, C.R. Mechanically induced osteogenic differentiation-the role of RhoA, ROCKII and cytoskeletal dynamics. J Cell Sci 122, 546, 2009.
    • (2009) J Cell Sci , vol.122 , pp. 546
    • Arnsdorf, E.J.1    Tummala, P.2    Kwon, R.Y.3    Jacobs, C.R.4
  • 71
    • 15444368753 scopus 로고    scopus 로고
    • The effect of cytoskeletal disruption on pulsatile fluid flow-induced nitric oxide and prostaglandin E2 release in oste-ocytes and osteoblasts
    • McGarry, J.G., Klein-Nulend, J., and Prendergast, P.J. The effect of cytoskeletal disruption on pulsatile fluid flow-induced nitric oxide and prostaglandin E2 release in oste-ocytes and osteoblasts. Biochem Biophys Res Commun 330, 341, 2005.
    • (2005) Biochem Biophys Res Commun , vol.330 , pp. 341
    • McGarry, J.G.1    Klein-Nulend, J.2    Prendergast, P.J.3
  • 72
    • 3042636110 scopus 로고    scopus 로고
    • Porosity variation in hydroxyapatite and osteoblast morphology: A scanning electron microscopy study
    • Annaz, B., Hing, K., Kayser, M., Buckland, T., and Silvio, L.D. Porosity variation in hydroxyapatite and osteoblast morphology: a scanning electron microscopy study. J Microsc 215, 100, 2004.
    • (2004) J Microsc , vol.215 , pp. 100
    • Annaz, B.1    Hing, K.2    Kayser, M.3    Buckland, T.4    Silvio, L.D.5
  • 74
    • 46449125838 scopus 로고    scopus 로고
    • Mechanical stimulation of osteoblasts using steady and dynamic fluid flow
    • Jaasma, M.J., and O'Brien, F.J. Mechanical stimulation of osteoblasts using steady and dynamic fluid flow. Tissue Eng Part A 14, 1213, 2008.
    • (2008) Tissue Eng Part A , vol.14 , pp. 1213
    • Jaasma, M.J.1    O'Brien, F.J.2
  • 75
    • 78649892298 scopus 로고    scopus 로고
    • Stimulation of osteoblasts using rest periods during bioreactor culture on collagen-glycosaminoglycan scaffolds
    • Partap, S., Plunkett, N., Kelly, D., and O'Brien, F. Stimulation of osteoblasts using rest periods during bioreactor culture on collagen- glycosaminoglycan scaffolds. J Mater Sci Mater Med 21, 2325, 2010.
    • (2010) J Mater Sci Mater Med , vol.21 , pp. 2325
    • Partap, S.1    Plunkett, N.2    Kelly, D.3    O'Brien, F.4
  • 76
    • 77649257417 scopus 로고    scopus 로고
    • Osteoblast response to rest periods during bioreactor culture of collagen-glycosaminoglycan scaffolds
    • Plunkett, N.A., Partap, S., and O'Brien, F.J. Osteoblast response to rest periods during bioreactor culture of collagen-glycosaminoglycan scaffolds. Tissue Eng Part A 16, 943, 2010.
    • (2010) Tissue Eng Part A , vol.16 , pp. 943
    • Plunkett, N.A.1    Partap, S.2    O'Brien, F.J.3
  • 77
    • 59449110766 scopus 로고    scopus 로고
    • Effect of low-frequency pulsatile flow on expression of osteoblastic genes by bone marrow stromal cells
    • Sharp, L., Lee, Y., and Goldstein, A. Effect of low-frequency pulsatile flow on expression of osteoblastic genes by bone marrow stromal cells. Ann Biomed Eng 37, 445, 2009.
    • (2009) Ann Biomed Eng , vol.37 , pp. 445
    • Sharp, L.1    Lee, Y.2    Goldstein, A.3
  • 78
    • 20444389065 scopus 로고    scopus 로고
    • Fluid flow stimulates expression of osteopontin and bone sialoprotein by bone marrow stromal cells in a temporally dependent manner
    • Kreke, M.R., Huckle, W.R., and Goldstein, A.S. Fluid flow stimulates expression of osteopontin and bone sialoprotein by bone marrow stromal cells in a temporally dependent manner. Bone 36, 1047, 2005.
    • (2005) Bone , vol.36 , pp. 1047
    • Kreke, M.R.1    Huckle, W.R.2    Goldstein, A.S.3
  • 79
    • 22044439283 scopus 로고    scopus 로고
    • Effects of short-term recovery periods on fluid-induced signaling in osteoblastic cells
    • Batra, N.N., Li, Y.J., Yellowley, C.E., et al. Effects of short-term recovery periods on fluid-induced signaling in osteoblastic cells. J Biomech 38, 1909, 2005.
    • (2005) J Biomech , vol.38 , pp. 1909
    • Batra, N.N.1    Li, Y.J.2    Yellowley, C.E.3
  • 80
    • 42049100497 scopus 로고    scopus 로고
    • Effect of intermittent shear stress on mechanotransductive signaling and osteoblastic differentiation of bone marrow stromal cells
    • Kreke, M.R., Sharp, L.A., Lee, Y.W., and Goldstein, A.S. Effect of intermittent shear stress on mechanotransductive signaling and osteoblastic differentiation of bone marrow stromal cells. Tissue Eng Part A 14, 529, 2008.
    • (2008) Tissue Eng Part A , vol.14 , pp. 529
    • Kreke, M.R.1    Sharp, L.A.2    Lee, Y.W.3    Goldstein, A.S.4
  • 81
    • 31044449357 scopus 로고    scopus 로고
    • Mechanical stimulation of MC3T3 osteoblastic cells in a bone tissue-engineering bioreactor enhances prostaglandin E2 release
    • Vance, J., Galley, S., Liu, D.F., and Donahue, S.W. Mechanical stimulation of MC3T3 osteoblastic cells in a bone tissue-engineering bioreactor enhances prostaglandin E2 release. Tissue Eng 11, 1832, 2005.
    • (2005) Tissue Eng , vol.11 , pp. 1832
    • Vance, J.1    Galley, S.2    Liu, D.F.3    Donahue, S.W.4
  • 82
    • 0035918140 scopus 로고    scopus 로고
    • Osteopontin gene regulation by oscillatory fluid flow via intracellular calcium mobilization and activation of mitogen-activated protein kinase in MC3T3-E1 osteoblasts
    • You, J., Reilly, G.C., Zhen, X., et al. Osteopontin gene regulation by oscillatory fluid flow via intracellular calcium mobilization and activation of mitogen-activated protein kinase in MC3T3-E1 osteoblasts. J Biol Chem 276, 13365, 2001.
    • (2001) J Biol Chem , vol.276 , pp. 13365
    • You, J.1    Reilly, G.C.2    Zhen, X.3
  • 83
    • 33645452566 scopus 로고    scopus 로고
    • MAP kinase and calcium signaling mediate fluid flow-induced human mesenchymal stem cell proliferation
    • Riddle, R.C., Taylor, A.F., Genetos, D.C., and Donahue, H.J. MAP kinase and calcium signaling mediate fluid flow-induced human mesenchymal stem cell proliferation. Am J Physiol Cell Physiol 290, C776, 2006.
    • (2006) Am J Physiol Cell Physiol , vol.290
    • Riddle, R.C.1    Taylor, A.F.2    Genetos, D.C.3    Donahue, H.J.4
  • 84
    • 0033804637 scopus 로고    scopus 로고
    • Substrate deformation levels associated with routine physical activity are less stimulatory to bone cells relative to loading-induced oscillatory fluid flow
    • You, J., Yellowley, C.E., Donahue, H.J., et al. Substrate deformation levels associated with routine physical activity are less stimulatory to bone cells relative to loading-induced oscillatory fluid flow. J Biomech Eng 122, 387, 2000.
    • (2000) J Biomech Eng , vol.122 , pp. 387
    • You, J.1    Yellowley, C.E.2    Donahue, H.J.3
  • 85
    • 0345598939 scopus 로고    scopus 로고
    • Mineralized matrix deposition by marrow stromal osteoblasts in 3D perfusion culture increases with increasing fluid shear forces
    • Sikavitsas, V.I., Bancroft, G.N., Holtorf, H.L., Jansen, J.A., and Mikos, A.G. Mineralized matrix deposition by marrow stromal osteoblasts in 3D perfusion culture increases with increasing fluid shear forces. Proc Natl Acad Sci USA 100, 14683, 2003.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 14683
    • Sikavitsas, V.I.1    Bancroft, G.N.2    Holtorf, H.L.3    Jansen, J.A.4    Mikos, A.G.5
  • 86
    • 17044418448 scopus 로고    scopus 로고
    • Flow perfu-sion enhances the calcified matrix deposition of marrow stromal cells in biodegradable nonwoven fiber mesh scaffolds
    • Sikavitsas, V., Bancroft, G., Lemoine, J., et al. Flow perfu-sion enhances the calcified matrix deposition of marrow stromal cells in biodegradable nonwoven fiber mesh scaffolds. Ann Biomed Eng 33, 63, 2005.
    • (2005) Ann Biomed Eng , vol.33 , pp. 63
    • Sikavitsas, V.1    Bancroft, G.2    Lemoine, J.3
  • 87
    • 33846928754 scopus 로고    scopus 로고
    • Effects of shear stress on 3D human mesenchymal stem cell construct development in a perfusion bioreactor system: Experiments and hydrody-namic modeling
    • Zhao, F., Chella, R., and Ma, T. Effects of shear stress on 3D human mesenchymal stem cell construct development in a perfusion bioreactor system: experiments and hydrody-namic modeling. Biotechnol Bioeng 96, 584, 2007.
    • (2007) Biotechnol Bioeng , vol.96 , pp. 584
    • Zhao, F.1    Chella, R.2    Ma, T.3
  • 88
    • 34547943045 scopus 로고    scopus 로고
    • Improved mes-enchymal stem cell seeding on RGD-modified poly(L-lactic acid) scaffolds using flow perfusion
    • Alvarez-Barreto, J.F., and Sikavitsas, V.I. Improved mes-enchymal stem cell seeding on RGD-modified poly(L-lactic acid) scaffolds using flow perfusion. Macromol Biosci 7, 579, 2007.
    • (2007) Macromol Biosci , vol.7 , pp. 579
    • Alvarez-Barreto, J.F.1    Sikavitsas, V.I.2
  • 89
    • 33847262631 scopus 로고    scopus 로고
    • Flow perfusion improves seeding of tissue engineering scaffolds with different architectures
    • Alvarez-Barreto, J., Linehan, S., Shambaugh, R., and Sika-vitsas, V. Flow perfusion improves seeding of tissue engineering scaffolds with different architectures. Ann Biomed Eng 35, 429, 2007.
    • (2007) Ann Biomed Eng , vol.35 , pp. 429
    • Alvarez-Barreto, J.1    Linehan, S.2    Shambaugh, R.3    Sika-Vitsas, V.4
  • 90
    • 31044451130 scopus 로고    scopus 로고
    • Adipose tissue-derived mesenchymal stem cells acquire bone cell-like responsiveness to fluid shear stress on osteogenic stimulation
    • Knippenberg, M., Helder, M.N., Doulabi, B.Z., et al. Adipose tissue-derived mesenchymal stem cells acquire bone cell-like responsiveness to fluid shear stress on osteogenic stimulation. Tissue Eng 11, 1780, 2005.
    • (2005) Tissue Eng , vol.11 , pp. 1780
    • Knippenberg, M.1    Helder, M.N.2    Doulabi, B.Z.3
  • 91
    • 0035062331 scopus 로고    scopus 로고
    • Osteoblasts respond to pulsatile fluid flow with short-term increases in PGE2 but no change in mineralization
    • Nauman, E.A., Satcher, R.L., Keaveny, T.M., Halloran, B.P., and Bikle, D.D. Osteoblasts respond to pulsatile fluid flow with short-term increases in PGE2 but no change in mineralization. J Appl Physiol 90, 1849, 2001.
    • (2001) J Appl Physiol , vol.90 , pp. 1849
    • Nauman, E.A.1    Satcher, R.L.2    Keaveny, T.M.3    Halloran, B.P.4    Bikle, D.D.5
  • 92
  • 93
    • 3042856043 scopus 로고    scopus 로고
    • Hydrodynamic shear stimulates osteocalcin expression but not proliferation of bone marrow stromal cells
    • Kreke, M.R., and Goldstein, A.S. Hydrodynamic shear stimulates osteocalcin expression but not proliferation of bone marrow stromal cells. Tissue Eng 10, 780, 2004.
    • (2004) Tissue Eng , vol.10 , pp. 780
    • Kreke, M.R.1    Goldstein, A.S.2
  • 94
    • 4844230009 scopus 로고    scopus 로고
    • Oscillatory fluid flow affects human marrow stromal cell proliferation and differentiation
    • Li, Y.J., Batra, N.N., You, L., et al. Oscillatory fluid flow affects human marrow stromal cell proliferation and differentiation. J Orthop Res 22, 1283, 2004.
    • (2004) J Orthop Res , vol.22 , pp. 1283
    • Li, Y.J.1    Batra, N.N.2    You, L.3
  • 95
    • 0037345529 scopus 로고    scopus 로고
    • Fluid flow shear stress stimulates human osteoblast proliferation and differentiation through multiple interacting and competing signal transduction pathways
    • Kapur, S., Baylink, D.J., and William Lau, K.H. Fluid flow shear stress stimulates human osteoblast proliferation and differentiation through multiple interacting and competing signal transduction pathways. Bone 32, 241, 2003.
    • (2003) Bone , vol.32 , pp. 241
    • Kapur, S.1    Baylink, D.J.2    William Lau, K.H.3
  • 96
    • 14644436314 scopus 로고    scopus 로고
    • A comparison of strain and fluid shear stress in stimulating bone cell responses-a computational and experimental study
    • McGarry, J.G., Klein-Nulend, J., Mullender, M.G., and Prendergast, P.J. A comparison of strain and fluid shear stress in stimulating bone cell responses-a computational and experimental study. FASEB J 19, 482, 2004.
    • (2004) FASEB J , vol.19 , pp. 482
    • McGarry, J.G.1    Klein-Nulend, J.2    Mullender, M.G.3    Prendergast, P.J.4
  • 97
    • 0033397493 scopus 로고    scopus 로고
    • Medium perfusion enhances osteogenesis by murine osteosarcoma cells in three-dimensional collagen sponges
    • Mueller, S.M., Mizuno, S., Gerstenfeld, L.C., and Glowacki, J. Medium perfusion enhances osteogenesis by murine osteosarcoma cells in three-dimensional collagen sponges. J Bone Miner Res 14, 2118, 1999.
    • (1999) J Bone Miner Res , vol.14 , pp. 2118
    • Mueller, S.M.1    Mizuno, S.2    Gerstenfeld, L.C.3    Glowacki, J.4
  • 98
    • 0345015415 scopus 로고    scopus 로고
    • Effects of medium perfusion rate on cell-seeded three-dimensional bone constructs invitro
    • Cartmell, S., Porter, B.D., Garc?́a, A.J., and Guldberg, R.E. Effects of medium perfusion rate on cell-seeded three-dimensional bone constructs invitro. Tissue Eng9, 1197, 2003.
    • (2003) Tissue Eng , vol.9 , pp. 1197
    • Cartmell, S.1    Porter, B.D.2    García, A.J.3    Guldberg, R.E.4
  • 99
    • 22244450402 scopus 로고    scopus 로고
    • Scaffold mesh size affects the osteoblastic differentiation of seeded marrow stromal cells cultured in a flow perfusion bioreactor
    • Holtorf, H.L., Datta, N., Jansen, J.A., and Mikos, A.G. Scaffold mesh size affects the osteoblastic differentiation of seeded marrow stromal cells cultured in a flow perfusion bioreactor. J Biomed Mater Res Part A 74A, 171, 2005.
    • (2005) J Biomed Mater Res Part A , vol.74 A , pp. 171
    • Holtorf, H.L.1    Datta, N.2    Jansen, J.A.3    Mikos, A.G.4
  • 100
    • 13944270566 scopus 로고    scopus 로고
    • Flow perfusion culture induces the osteoblastic differentiation of marrow stromal cell-scaffold constructs in the absence of dexa-methasone
    • Holtorf, H.L., Jansen, J.A., and Mikos, A.G. Flow perfusion culture induces the osteoblastic differentiation of marrow stromal cell-scaffold constructs in the absence of dexa-methasone. J Biomed Mater Res Part A 72A, 326, 2005.
    • (2005) J Biomed Mater Res Part A , vol.72 A , pp. 326
    • Holtorf, H.L.1    Jansen, J.A.2    Mikos, A.G.3
  • 101
    • 24144472548 scopus 로고    scopus 로고
    • Flow perfusion culture of marrow stromal cells seeded on porous biphasic calcium phosphate ceramics
    • Holtorf, H.L., Sheffield, T.L., Ambrose, C.G., Jansen, J.A., and Mikos, A.G. Flow perfusion culture of marrow stromal cells seeded on porous biphasic calcium phosphate ceramics. Ann Biomed Eng 33, 1238, 2005.
    • (2005) Ann Biomed Eng , vol.33 , pp. 1238
    • Holtorf, H.L.1    Sheffield, T.L.2    Ambrose, C.G.3    Jansen, J.A.4    Mikos, A.G.5
  • 102
    • 63149130693 scopus 로고    scopus 로고
    • Deformation simulation of cells seeded on a collagen-GAG scaffold in a flow perfusion bioreactor using a sequential 3D CFD-elastostatics model
    • Jungreuthmayer, C., Jaasma, M., Al-Munajjed, A., et al. Deformation simulation of cells seeded on a collagen-GAG scaffold in a flow perfusion bioreactor using a sequential 3D CFD-elastostatics model. Med Eng Phys 31, 420, 2009.
    • (2009) Med Eng Phys , vol.31 , pp. 420
    • Jungreuthmayer, C.1    Jaasma, M.2    Al-Munajjed, A.3
  • 103
    • 34249661685 scopus 로고    scopus 로고
    • Adaptation of cellular mechanical behavior to mechanical loading for osteoblastic cells
    • Jaasma, M.J., Jackson, W.M., Tang, R.Y., and Keaveny, T.M. Adaptation of cellular mechanical behavior to mechanical loading for osteoblastic cells. J Biomech 40, 1938, 2007.
    • (2007) J Biomech , vol.40 , pp. 1938
    • Jaasma, M.J.1    Jackson, W.M.2    Tang, R.Y.3    Keaveny, T.M.4
  • 104
    • 57049185878 scopus 로고    scopus 로고
    • Mechanical loading by fluid shear is sufficient to alter the cytoskeletal composition of osteoblastic cells
    • Jackson, W.M., Jaasma, M.J., Tang, R.S., and Keaveny, T.M. Mechanical loading by fluid shear is sufficient to alter the cytoskeletal composition of osteoblastic cells. Am J Physiol Cell Physiol 295, C1005, 2008.
    • (2008) Am J Physiol Cell Physiol , vol.295
    • Jackson, W.M.1    Jaasma, M.J.2    Tang, R.S.3    Keaveny, T.M.4
  • 105
    • 0033574746 scopus 로고    scopus 로고
    • Functional arteries grown in vitro
    • Niklason, L.E., Gao, J., Abbott, W.M., et al. Functional arteries grown in vitro. Science 284, 489, 1999.
    • (1999) Science , vol.284 , pp. 489
    • Niklason, L.E.1    Gao, J.2    Abbott, W.M.3
  • 106
    • 0035099520 scopus 로고    scopus 로고
    • Morphologic and mechanical characteristics of engineered bovine arteries
    • Niklason, L.E., Abbott, W., Gao, J., et al. Morphologic and mechanical characteristics of engineered bovine arteries. J Vasc Surg 33, 628, 2001.
    • (2001) J Vasc Surg , vol.33 , pp. 628
    • Niklason, L.E.1    Abbott, W.2    Gao, J.3
  • 107
    • 44349105193 scopus 로고    scopus 로고
    • Cyclic distension of fibrin-based tissue constructs: Evidence of adaptation during growth of engineered connective tissue
    • Syedain, Z.H., Weinberg, J.S., and Tranquillo, R.T. Cyclic distension of fibrin-based tissue constructs: evidence of adaptation during growth of engineered connective tissue. Proc Natl Acad Sci 105, 6537, 2008.
    • (2008) Proc Natl Acad Sci , vol.105 , pp. 6537
    • Syedain, Z.H.1    Weinberg, J.S.2    Tranquillo, R.T.3
  • 108
    • 2942553906 scopus 로고    scopus 로고
    • Effects of cyclic compressive loading on chondrogen-esis of rabbit bone-marrow derived mesenchymal stem cells
    • Huang, C.C., Hagar, K.L., Frost, L.E., Sun, Y., and Cheung, H.S. Effects of cyclic compressive loading on chondrogen-esis of rabbit bone-marrow derived mesenchymal stem cells. Stem Cells 22, 313, 2004.
    • (2004) Stem Cells , vol.22 , pp. 313
    • Huang, C.C.1    Hagar, K.L.2    Frost, L.E.3    Sun, Y.4    Cheung, H.S.5
  • 109
    • 34548548381 scopus 로고    scopus 로고
    • The beneficial effect of delayed compressive loading on tissue-engineered cartilage constructs cultured with TGF-[beta]3
    • Lima, E., Bian, L., Ng, K., et al. The beneficial effect of delayed compressive loading on tissue-engineered cartilage constructs cultured with TGF-[beta]3. Osteoarthritis Cartilage 15, 1025, 2007.
    • (2007) Osteoarthritis Cartilage , vol.15 , pp. 1025
    • Lima, E.1    Bian, L.2    Ng, K.3
  • 110
    • 0034210117 scopus 로고    scopus 로고
    • Functional tissue engineering of articular cartilage through dynamic loading of chondrocyte-seeded agarose gels
    • Mauck, R.L., Soltz, M.A., Wang, C.C.B., et al. Functional tissue engineering of articular cartilage through dynamic loading of chondrocyte-seeded agarose gels. J Biomech Eng 122, 252, 2000.
    • (2000) J Biomech Eng , vol.122 , pp. 252
    • Mauck, R.L.1    Soltz, M.A.2    Wang, C.C.B.3
  • 111
    • 33845412455 scopus 로고    scopus 로고
    • Regulation of cartilaginous ECM gene transcription by chondrocytes and MSCs in 3D culture in response to dynamic loading
    • Mauck, R., Byers, B., Yuan, X., and Tuan, R. Regulation of cartilaginous ECM gene transcription by chondrocytes and MSCs in 3D culture in response to dynamic loading. Bio-mech Model Mechanobiol 6, 113, 2007.
    • (2007) Bio-mech Model Mechanobiol , vol.6 , pp. 113
    • Mauck, R.1    Byers, B.2    Yuan, X.3    Tuan, R.4
  • 112
    • 71849115721 scopus 로고    scopus 로고
    • The role of mechanical loading in ligament tissue engineering
    • Benhardt, H.A., and Cosgriff-Hernandez, E.M. The role of mechanical loading in ligament tissue engineering. Tissue Eng Part B Rev 15, 467, 2009.
    • (2009) Tissue Eng Part B Rev , vol.15 , pp. 467
    • Benhardt, H.A.1    Cosgriff-Hernandez, E.M.2
  • 114
    • 70450218407 scopus 로고    scopus 로고
    • Endothelial differentiation of amniotic fluid-derived stem cells: Synergism of biochemical and shear force stimuli
    • Zhang, P., Baxter, J., Vinod, K., Tulenko, T.N., and Di Muzio, P.J. Endothelial differentiation of amniotic fluid-derived stem cells: synergism of biochemical and shear force stimuli. Stem Cells Dev 18, 1299, 2009.
    • (2009) Stem Cells Dev , vol.18 , pp. 1299
    • Zhang, P.1    Baxter, J.2    Vinod, K.3    Tulenko, T.N.4    Di Muzio, P.J.5
  • 115
    • 0036721376 scopus 로고    scopus 로고
    • Prolonged fluid shear stress induces a distinct set of endothelial cell genes, most specifically lung Kruppel-like factor (KLF2)
    • Dekker, R.J., Van Soest, S., Fontijn, R.D., et al. Prolonged fluid shear stress induces a distinct set of endothelial cell genes, most specifically lung Kruppel-like factor (KLF2). Blood 100, 1689, 2002.
    • (2002) Blood , vol.100 , pp. 1689
    • Dekker, R.J.1    Van Soest, S.2    Fontijn, R.D.3
  • 116
    • 12344270931 scopus 로고    scopus 로고
    • Down-regulation of endothelial ephrinB2 expression by laminar shear stress
    • Goettsch, W., Augustin, H.G., and Morawietz, H. Down-regulation of endothelial ephrinB2 expression by laminar shear stress. Endothelium 11, 259, 2004.
    • (2004) Endothelium , vol.11 , pp. 259
    • Goettsch, W.1    Augustin, H.G.2    Morawietz, H.3
  • 117
    • 39749100044 scopus 로고    scopus 로고
    • Synergism of biochemical and mechanical stimuli in the differentiation of human placenta-derived multipotent cells into endothelial cells
    • Wu, C., Chao, Y., Chen, C., et al. Synergism of biochemical and mechanical stimuli in the differentiation of human placenta-derived multipotent cells into endothelial cells. J Biomech 41, 813, 2008.
    • (2008) J Biomech , vol.41 , pp. 813
    • Wu, C.1    Chao, Y.2    Chen, C.3
  • 118
    • 50349092861 scopus 로고    scopus 로고
    • Shear stress and vascular smooth muscle cells promote endothelial differentiation of endothelial progenitor cells via activation of Akt
    • Ye, C., Bai, L., Yan, Z., Wang, Y., and Jiang, Z. Shear stress and vascular smooth muscle cells promote endothelial differentiation of endothelial progenitor cells via activation of Akt. Clin Biomech 23, S118, 2008.
    • (2008) Clin Biomech , vol.23
    • Ye, C.1    Bai, L.2    Yan, Z.3    Wang, Y.4    Jiang, Z.5
  • 119
    • 58649097753 scopus 로고    scopus 로고
    • Fluid shear stress induces arterial differentiation of endothelial progenitor cells
    • Obi, S., Yamamoto, K., Shimizu, N., et al. Fluid shear stress induces arterial differentiation of endothelial progenitor cells. J Appl Physiol 106, 203, 2009.
    • (2009) J Appl Physiol , vol.106 , pp. 203
    • Obi, S.1    Yamamoto, K.2    Shimizu, N.3
  • 120
    • 0142180220 scopus 로고    scopus 로고
    • Proliferation, differentiation, and tube formation by endothelial progenitor cells in response to shear stress
    • Yamamoto, K., Takahashi, T., Asahara, T., et al. Proliferation, differentiation, and tube formation by endothelial progenitor cells in response to shear stress. J Appl Physiol 95, 2081, 2003.
    • (2003) J Appl Physiol , vol.95 , pp. 2081
    • Yamamoto, K.1    Takahashi, T.2    Asahara, T.3
  • 121
    • 66349095418 scopus 로고    scopus 로고
    • Endothelial differentiation of adipose-derived stem cells: Effects of en-dothelial cell growth supplement and shear force
    • Fischer, L.J., McIlhenny, S., Tulenko, T., et al. Endothelial differentiation of adipose-derived stem cells: effects of en-dothelial cell growth supplement and shear force. J Surg Res 152, 157, 2009.
    • (2009) J Surg Res , vol.152 , pp. 157
    • Fischer, L.J.1    McIlhenny, S.2    Tulenko, T.3
  • 122
    • 27644453468 scopus 로고    scopus 로고
    • Synergy between interstitial flow and VEGF directs capillary morphogenesis in vitro through a gradient amplification mechanism
    • Helm, C.E., Fleury, M.E., Zisch, A.H., Boschetti, F., and Swartz, M.A. Synergy between interstitial flow and VEGF directs capillary morphogenesis in vitro through a gradient amplification mechanism. Proc Natl Acad Sci USA 102, 15779, 2005.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 15779
    • Helm, C.E.1    Fleury, M.E.2    Zisch, A.H.3    Boschetti, F.4    Swartz, M.A.5
  • 123
    • 0041860919 scopus 로고    scopus 로고
    • Effects of pulsatile shear stress on nitric oxide production and en-dothelial cell nitric oxide synthase expression by ovine feto-placental artery endothelial cells
    • Li, Y., Zheng, J., Bird, I.M., and Magness, R.R. Effects of pulsatile shear stress on nitric oxide production and en-dothelial cell nitric oxide synthase expression by ovine feto-placental artery endothelial cells. Biol Reprod 69, 1053, 2003.
    • (2003) Biol Reprod , vol.69 , pp. 1053
    • Li, Y.1    Zheng, J.2    Bird, I.M.3    Magness, R.R.4
  • 124
    • 0037189589 scopus 로고    scopus 로고
    • Shear stress-induced release of basic fibroblast growth factor from endothelial cells is mediated by matrix interaction via integrin aVb3
    • Gloe, T., Sohn, H.Y., Meininger, G.A., and Pohl, U. Shear stress-induced release of basic fibroblast growth factor from endothelial cells is mediated by matrix interaction via integrin aVb3. J Biol Chem 277, 23453, 2002.
    • (2002) J Biol Chem , vol.277 , pp. 23453
    • Gloe, T.1    Sohn, H.Y.2    Meininger, G.A.3    Pohl, U.4
  • 125
    • 36549035306 scopus 로고    scopus 로고
    • Fluid shear stress upregulates vascular endothelial growth factor gene expression in osteoblasts
    • Thi, M.M., Iacobas, D.A., Iacobas, S., and Spray, D.C. Fluid shear stress upregulates vascular endothelial growth factor gene expression in osteoblasts. Ann N Y Acad Sci 1117, 73, 2007.
    • (2007) Ann N y Acad Sci , vol.1117 , pp. 73
    • Thi, M.M.1    Iacobas, D.A.2    Iacobas, S.3    Spray, D.C.4
  • 126
    • 24144432913 scopus 로고    scopus 로고
    • Shear stress induces endothelial differentiation from a murine embryonic mes-enchymal progenitor cell line
    • Wang, H., Riha, G.M., Yan, S., et al. Shear stress induces endothelial differentiation from a murine embryonic mes-enchymal progenitor cell line. Arterioscler Thromb Vasc Biol 25, 1817, 2005.
    • (2005) Arterioscler Thromb Vasc Biol , vol.25 , pp. 1817
    • Wang, H.1    Riha, G.M.2    Yan, S.3
  • 127
    • 33745207763 scopus 로고    scopus 로고
    • Shear stress induces en-dothelial transdifferentiation from mouse smooth muscle cells
    • Wang, H., Yan, S., Chai, H., et al. Shear stress induces en-dothelial transdifferentiation from mouse smooth muscle cells. Biochem Biophys Res Commun 346, 860, 2006.
    • (2006) Biochem Biophys Res Commun , vol.346 , pp. 860
    • Wang, H.1    Yan, S.2    Chai, H.3
  • 128
    • 33749027242 scopus 로고    scopus 로고
    • HDAC3 is crucial in shear- and VEGF-induced stem cell differentiation toward endothelial cells
    • Zeng, L., Xiao, Q., Margariti, A., et al. HDAC3 is crucial in shear- and VEGF-induced stem cell differentiation toward endothelial cells. J Cell Biol 174, 1059, 2006.
    • (2006) J Cell Biol , vol.174 , pp. 1059
    • Zeng, L.1    Xiao, Q.2    Margariti, A.3
  • 130
    • 23744442185 scopus 로고    scopus 로고
    • Differentiation from embryonic stem cells to vascular wall cells under in vitro pulsatile flow loading
    • Huang, H., Nakayama, Y., Qin, K., et al. Differentiation from embryonic stem cells to vascular wall cells unDer in vitro pulsatile flow loading. J Artif Organs 8, 110, 2005.
    • (2005) J Artif Organs , vol.8 , pp. 110
    • Huang, H.1    Nakayama, Y.2    Qin, K.3
  • 131
    • 0035831513 scopus 로고    scopus 로고
    • Fluid shear stress induced cyclooxygenase-2 expression is mediated by C/EBPb, cAMP-response element binding protein, and AP-1 in osteoblastic MC3T3-E1 cells
    • Ogasawara, A., Arakawa, T., Kaneda, T., et al. Fluid shear stress induced cyclooxygenase-2 expression is mediated by C/EBPb, cAMP-response element binding protein, and AP-1 in osteoblastic MC3T3-E1 cells. J Biol Chem 276, 7048, 2001.
    • (2001) J Biol Chem , vol.276 , pp. 7048
    • Ogasawara, A.1    Arakawa, T.2    Kaneda, T.3
  • 132
    • 0031254183 scopus 로고    scopus 로고
    • Induction of No and prostaglandin E2 in osteoblasts by wall shear stress but not mechanical strain
    • Smalt, R., Mitchell, F.T., Howard, R.L., and Chambers, T.J. Induction of No and prostaglandin E2 in osteoblasts by wall shear stress but not mechanical strain. Am J Physiol Endocrinol Metab 273, E751, 1997.
    • (1997) Am J Physiol Endocrinol Metab , vol.273
    • Smalt, R.1    Mitchell, F.T.2    Howard, R.L.3    Chambers, T.J.4
  • 133
    • 20144385079 scopus 로고    scopus 로고
    • Fluid shear stress induces differentiation of FLK-1-positive embryonic stem cells into vascular endothelial cells in vitro
    • Yamamoto, K., Sokabe, T., Watabe, T., et al. Fluid shear stress induces differentiation of FLK-1-positive embryonic stem cells into vascular endothelial cells in vitro. Am J Physiol Heart Circ Physiol 288, H1915, 2005.
    • (2005) Am J Physiol Heart Circ Physiol , vol.288
    • Yamamoto, K.1    Sokabe, T.2    Watabe, T.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.