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Volumn 112, Issue , 2009, Pages 251-268

Fluid dynamics in bioreactor design: Considerations for the theoretical and practical approach

Author keywords

Bioreactor; Computational fluid dynamics; Flow pattern; Fluid dynamics; Laminar flow; Perfusion system; Pulsatile flow; Rotating vessel; Shear stress; Stirring system

Indexed keywords

TISSUE SCAFFOLD;

EID: 62849118753     PISSN: 07246145     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-3-540-69357-4_11     Document Type: Review
Times cited : (16)

References (61)
  • 2
    • 62849127854 scopus 로고    scopus 로고
    • 2. Auflage, Springer-Verlag, Berlin Heidelberg New York
    • Von Böckh P (2004) Fluidmechanik. 2. Auflage, Springer-Verlag, Berlin Heidelberg New York
    • (2004) Fluidmechanik
    • Von Böckh, P.1
  • 3
    • 4444324523 scopus 로고
    • 6. überarbeitete Auflage. Herausgeber Th. Lehmann, Verlag Vieweg, Braunschweig, Wiesbaden
    • Gersten K (1991) Einführung in die Strömungsmechanik, 6. überarbeitete Auflage. Herausgeber Th. Lehmann, Verlag Vieweg, Braunschweig, Wiesbaden
    • (1991) Einführung in die Strömungsmechanik
    • Gersten, K.1
  • 5
    • 18844400298 scopus 로고    scopus 로고
    • Fluid dynamics in stirred vessels - experiments and simulations of single-phase and liquid-liquid systems
    • Göteburg, Sweden
    • Svensson FJE (2005) Fluid dynamics in stirred vessels - experiments and simulations of single-phase and liquid-liquid systems. Chalmers University of Technology, Chalmers Reproservice, Göteburg, Sweden
    • (2005) Chalmers University of Technology, Chalmers Reproservice
    • Svensson, F.J.E.1
  • 7
    • 0027071772 scopus 로고
    • Shear stress induced variation of cell condition and productivity
    • Ludwig A, Kretzmer G (1993) Shear stress induced variation of cell condition and productivity. J Biotechnol 27:217-223
    • (1993) J Biotechnol , vol.27 , pp. 217-223
    • Ludwig, A.1    Kretzmer, G.2
  • 8
    • 0027149422 scopus 로고
    • Animal cells in turbulent fluids: Details of the physical stimulus and the biological response
    • Cherry RS (1993) Animal cells in turbulent fluids: details of the physical stimulus and the biological response. Biotechnol Adv 11:279-299
    • (1993) Biotechnol Adv , vol.11 , pp. 279-299
    • Cherry, R.S.1
  • 9
    • 0033058465 scopus 로고    scopus 로고
    • Short-term cell/substrate contact dynamics of subconfluent endothelial cells following exposure to laminar flow
    • Olivier LA, Yen J, Reichert WM, Truskey GA (1999) Short-term cell/substrate contact dynamics of subconfluent endothelial cells following exposure to laminar flow. Biotechnol Prog 15:33-42
    • (1999) Biotechnol Prog , vol.15 , pp. 33-42
    • Olivier, L.A.1    Yen, J.2    Reichert, W.M.3    Truskey, G.A.4
  • 10
    • 0033585825 scopus 로고    scopus 로고
    • Cell death from bursting bubbles: Role of cell attachment to rising bubbles in sparged reactors
    • Meier SJ, Hatton A, Wang DIC (1999) Cell death from bursting bubbles: role of cell attachment to rising bubbles in sparged reactors. Biotechnol Bioeng 62(4):468-478
    • (1999) Biotechnol Bioeng , vol.62 , Issue.4 , pp. 468-478
    • Meier, S.J.1    Hatton, A.2    Wang, D.I.C.3
  • 11
    • 0033589373 scopus 로고    scopus 로고
    • Problems in predicting cell damage from bubble bursting
    • Dey D, Emery AN (1999) Problems in predicting cell damage from bubble bursting. Biotechnol Bioeng. 65(2):240-245
    • (1999) Biotechnol Bioeng , vol.65 , Issue.2 , pp. 240-245
    • Dey, D.1    Emery, A.N.2
  • 12
    • 33847767113 scopus 로고    scopus 로고
    • Mechanotransduction and endothelial cell homeostasis: The wisdom of the cell
    • Chien S (2007) Mechanotransduction and endothelial cell homeostasis: the wisdom of the cell. Am J Physiol Heart Circ Physiol 292:H1209-H1224
    • (2007) Am J Physiol Heart Circ Physiol , vol.292
    • Chien, S.1
  • 13
    • 0042668340 scopus 로고    scopus 로고
    • Adult human bone marrow-derived mesenchymal progenitor cells are capable of adhesion-independent survival and expansion
    • Baksh D, Davies JE, Zandstra PW (2003) Adult human bone marrow-derived mesenchymal progenitor cells are capable of adhesion-independent survival and expansion. Exp Haematol 31(8):723-732
    • (2003) Exp Haematol , vol.31 , Issue.8 , pp. 723-732
    • Baksh, D.1    Davies, J.E.2    Zandstra, P.W.3
  • 14
    • 0023092907 scopus 로고
    • Hydrodynamic effects on animal cells grown in microcarrier cultures
    • Croughan MS, Hamel J-F, Wang DIC (1987) Hydrodynamic effects on animal cells grown in microcarrier cultures. Biotechnol Bioeng 29:130-141
    • (1987) Biotechnol Bioeng , vol.29 , pp. 130-141
    • Croughan, M.S.1    Hamel, J.-F.2    Wang, D.I.C.3
  • 15
    • 0033302167 scopus 로고    scopus 로고
    • Nielsen LK (1999) Bioreactors for hematopoietic cell culture. Annu Rev Biomed Eng 01:129-152
    • Nielsen LK (1999) Bioreactors for hematopoietic cell culture. Annu Rev Biomed Eng 01:129-152
  • 16
    • 0014195418 scopus 로고
    • Growth of cell-strains and primary cells on micro-carriers in homogenous culture
    • Van Wezel AL (1967) Growth of cell-strains and primary cells on micro-carriers in homogenous culture. Nature 216(5110):64-65
    • (1967) Nature , vol.216 , Issue.5110 , pp. 64-65
    • Van Wezel, A.L.1
  • 17
    • 33745016900 scopus 로고    scopus 로고
    • Scale-up of breast cancer stem cell aggregate cultures to suspension bioreactors
    • Youn BS, Sen A, Behie LA, Girgis-Garbado A, Hassell JA (2006) Scale-up of breast cancer stem cell aggregate cultures to suspension bioreactors. Biotechnol Prog 22(3):801-810
    • (2006) Biotechnol Prog , vol.22 , Issue.3 , pp. 801-810
    • Youn, B.S.1    Sen, A.2    Behie, L.A.3    Girgis-Garbado, A.4    Hassell, J.A.5
  • 19
    • 20444389065 scopus 로고    scopus 로고
    • Fluid flow stimulates expression of osteopontin and bone sialoprotein by bone marrow stromal cells in a temporally dependent manner
    • Kreke MR, Huckle WR, Goldstein AS (2005) Fluid flow stimulates expression of osteopontin and bone sialoprotein by bone marrow stromal cells in a temporally dependent manner. Bone 36:1047-1055
    • (2005) Bone , vol.36 , pp. 1047-1055
    • Kreke, M.R.1    Huckle, W.R.2    Goldstein, A.S.3
  • 20
    • 0345598939 scopus 로고    scopus 로고
    • Mineralized matrix deposition by marrow stromal osteoblasts in 3D perfusion culture increases with increasing fluid shear forces
    • Sikavitas VI, Bancroft GN, Holtorf HL, Jansen JA, Mikos AG (2003) Mineralized matrix deposition by marrow stromal osteoblasts in 3D perfusion culture increases with increasing fluid shear forces. Proc Natl Acad Sci U S A 100(25):14683-14688
    • (2003) Proc Natl Acad Sci U S A , vol.100 , Issue.25 , pp. 14683-14688
    • Sikavitas, V.I.1    Bancroft, G.N.2    Holtorf, H.L.3    Jansen, J.A.4    Mikos, A.G.5
  • 21
    • 0344152914 scopus 로고    scopus 로고
    • Application of perfusion culture system improves in vitro and in vivo osteogenesis of bone marrow-derived osteoblastic cells in porous ceramic materials
    • Wang Y, Uemura T, Dong J, Kojima H, Tanaka J, Tateishi T (2003) Application of perfusion culture system improves in vitro and in vivo osteogenesis of bone marrow-derived osteoblastic cells in porous ceramic materials. Tissue Eng 9(6):1205-1214
    • (2003) Tissue Eng , vol.9 , Issue.6 , pp. 1205-1214
    • Wang, Y.1    Uemura, T.2    Dong, J.3    Kojima, H.4    Tanaka, J.5    Tateishi, T.6
  • 22
    • 3843112154 scopus 로고    scopus 로고
    • Bioreactor-based bone tissue engineering: The influence of dynamic flow on osteoblast phenotypic expression and matrix mineralization
    • Yu X, Botchwey EA, Levine EM, Pollack SR, Laurecin CT (2004) Bioreactor-based bone tissue engineering: the influence of dynamic flow on osteoblast phenotypic expression and matrix mineralization. Proc Natl Acad Sci U S A 101(31):11203-11208
    • (2004) Proc Natl Acad Sci U S A , vol.101 , Issue.31 , pp. 11203-11208
    • Yu, X.1    Botchwey, E.A.2    Levine, E.M.3    Pollack, S.R.4    Laurecin, C.T.5
  • 23
    • 0141942558 scopus 로고    scopus 로고
    • Using computational fluid dynamics software to estimate circulation time distributions in bioreactors
    • Davidson KM, Sushil S, Eggleton CD, Marten MR (2003) Using computational fluid dynamics software to estimate circulation time distributions in bioreactors. Biotechnol Prog 19:1480-1486
    • (2003) Biotechnol Prog , vol.19 , pp. 1480-1486
    • Davidson, K.M.1    Sushil, S.2    Eggleton, C.D.3    Marten, M.R.4
  • 25
    • 33751584179 scopus 로고    scopus 로고
    • Fluid dynamics of a micro-bioreactor for tissue engineering
    • Yu P, Lee TS, Zeng Y, Low HT (2005) Fluid dynamics of a micro-bioreactor for tissue engineering. Fluid Dya Mater Process 1(3):235-246
    • (2005) Fluid Dya Mater Process , vol.1 , Issue.3 , pp. 235-246
    • Yu, P.1    Lee, T.S.2    Zeng, Y.3    Low, H.T.4
  • 26
    • 34548251103 scopus 로고    scopus 로고
    • Location of scaffolds in bioreactors modulates the hydrodynamic environment experienced by engineered tissues
    • Bilgen B, Barabion GA (2007) Location of scaffolds in bioreactors modulates the hydrodynamic environment experienced by engineered tissues. Biotechnol Bioeng 98(1):282-294
    • (2007) Biotechnol Bioeng , vol.98 , Issue.1 , pp. 282-294
    • Bilgen, B.1    Barabion, G.A.2
  • 27
    • 16644365884 scopus 로고    scopus 로고
    • Increased rate of chondrocyte aggregation in a wavy-walled bioreactor
    • Bueno EM, Bilgen B, Carrier RL, Barabino GA (2004) Increased rate of chondrocyte aggregation in a wavy-walled bioreactor. Biotechnol Bioeng 88(6):767-777
    • (2004) Biotechnol Bioeng , vol.88 , Issue.6 , pp. 767-777
    • Bueno, E.M.1    Bilgen, B.2    Carrier, R.L.3    Barabino, G.A.4
  • 28
    • 33748569155 scopus 로고    scopus 로고
    • Bioreactors for tissue engineering
    • Chen H-C, Hu Y-C (2006) Bioreactors for tissue engineering. Biotechnol Lett 28:1415-1423
    • (2006) Biotechnol Lett , vol.28 , pp. 1415-1423
    • Chen, H.-C.1    Hu, Y.-C.2
  • 29
    • 3042817994 scopus 로고    scopus 로고
    • Perfusion bioreactor for small diameter tissue-engineered arteries
    • Wiliams C, Wick TM (2004) Perfusion bioreactor for small diameter tissue-engineered arteries. Tissue Eng 10(5/6):930-941
    • (2004) Tissue Eng , vol.10 , Issue.5-6 , pp. 930-941
    • Wiliams, C.1    Wick, T.M.2
  • 30
    • 84899661956 scopus 로고    scopus 로고
    • Israelowitz M, Rizvi S, von Schroeder HP, Holmes C, Gille C (2007) Laminar flow reactor. United States Patent Application, 11/895645
    • Israelowitz M, Rizvi S, von Schroeder HP, Holmes C, Gille C (2007) Laminar flow reactor. United States Patent Application, 11/895645
  • 31
    • 12344284982 scopus 로고    scopus 로고
    • 3-D computational modelling of media flow through scaffolds in a perfusion bioreactor
    • Porter B, Zauel R, Stockman H, Guldberg R, Fyhrie D (2005) 3-D computational modelling of media flow through scaffolds in a perfusion bioreactor. J Biomech 38:543-549
    • (2005) J Biomech , vol.38 , pp. 543-549
    • Porter, B.1    Zauel, R.2    Stockman, H.3    Guldberg, R.4    Fyhrie, D.5
  • 32
    • 34547592483 scopus 로고    scopus 로고
    • Flow modelling in a novel non-perfusion conical bioreactor
    • Singh H, Ang ES, Lim TT, Hutmacher DW (2007) Flow modelling in a novel non-perfusion conical bioreactor. Biotechnol Bioeng 97(5):1291-1299
    • (2007) Biotechnol Bioeng , vol.97 , Issue.5 , pp. 1291-1299
    • Singh, H.1    Ang, E.S.2    Lim, T.T.3    Hutmacher, D.W.4
  • 33
    • 32544432849 scopus 로고    scopus 로고
    • Modelling evaluation of the fluid-dynamic microenvironment in tissue engineered constructs: A micro-CT based model
    • Cioffi M, Boschetti F, Raimondi MT, Dubini G (2006) Modelling evaluation of the fluid-dynamic microenvironment in tissue engineered constructs: a micro-CT based model. Biotechnol Bioeng 93(3):500-510
    • (2006) Biotechnol Bioeng , vol.93 , Issue.3 , pp. 500-510
    • Cioffi, M.1    Boschetti, F.2    Raimondi, M.T.3    Dubini, G.4
  • 34
    • 34547613758 scopus 로고    scopus 로고
    • Enhancement of cell growth in tissue-engineering constructs under direct perfusion: Modelling and simulation
    • Chung CA, Chen CW, Chen CP, Tseng CS (2007) Enhancement of cell growth in tissue-engineering constructs under direct perfusion: modelling and simulation. Biotechnol Bioeng 97(6):1603-1616
    • (2007) Biotechnol Bioeng , vol.97 , Issue.6 , pp. 1603-1616
    • Chung, C.A.1    Chen, C.W.2    Chen, C.P.3    Tseng, C.S.4
  • 35
    • 0242438791 scopus 로고    scopus 로고
    • Convective flow through a hollow fiber bioartificial liver
    • Moussy Y (2003) Convective flow through a hollow fiber bioartificial liver. Artif Organs 27(11):1041-1049
    • (2003) Artif Organs , vol.27 , Issue.11 , pp. 1041-1049
    • Moussy, Y.1
  • 36
    • 0037021798 scopus 로고    scopus 로고
    • A novel multi-coaxial hollow fiber bioreactor for adherent cell types. Part 1: Hydrodynamic studies
    • Wolfe SP, Hsu E, Reid LM, Macdonald JM (2002) A novel multi-coaxial hollow fiber bioreactor for adherent cell types. Part 1: hydrodynamic studies. Biotechnol Bioeng 77(1):83-90
    • (2002) Biotechnol Bioeng , vol.77 , Issue.1 , pp. 83-90
    • Wolfe, S.P.1    Hsu, E.2    Reid, L.M.3    Macdonald, J.M.4
  • 37
    • 33750707949 scopus 로고    scopus 로고
    • Three-dimensional numerical modelling and computational fluid dynamics simulations to analyze and improve oxygen availability in the AMC bioartificial liver
    • Marfels G, Poyck PPC, Eloot S, Chamuleau RAFM, Verdonck PR (2006) Three-dimensional numerical modelling and computational fluid dynamics simulations to analyze and improve oxygen availability in the AMC bioartificial liver. Ann Biomed Eng 34(11):1729-1744
    • (2006) Ann Biomed Eng , vol.34 , Issue.11 , pp. 1729-1744
    • Marfels, G.1    Poyck, P.P.C.2    Eloot, S.3    Chamuleau, R.A.F.M.4    Verdonck, P.R.5
  • 38
    • 8644241679 scopus 로고    scopus 로고
    • Computerized microfluidic cell culture using elastomeric channels and Braille display
    • Gu W, Zhu X, Futai N, Cho BS, Takayama S (2004) Computerized microfluidic cell culture using elastomeric channels and Braille display. Proc Natl Acad Sci U S A 101(45):15861-15866
    • (2004) Proc Natl Acad Sci U S A , vol.101 , Issue.45 , pp. 15861-15866
    • Gu, W.1    Zhu, X.2    Futai, N.3    Cho, B.S.4    Takayama, S.5
  • 40
    • 0034610089 scopus 로고    scopus 로고
    • The fluid dynamic and shear environment in the NASA/JSC rotating-wall perfused-vessel bioreactor
    • Begley CM, Kleis SJ (2000) The fluid dynamic and shear environment in the NASA/JSC rotating-wall perfused-vessel bioreactor. Biotechnol Bioeng 70(1):32-40
    • (2000) Biotechnol Bioeng , vol.70 , Issue.1 , pp. 32-40
    • Begley, C.M.1    Kleis, S.J.2
  • 41
    • 16444371783 scopus 로고    scopus 로고
    • Oxygen transport and cell viability in an annular flow bioreactor: Comparison of laminar Coquette and Taylor-Vortex flow regimes
    • Curran SJ, Black RA (2005) Oxygen transport and cell viability in an annular flow bioreactor: comparison of laminar Coquette and Taylor-Vortex flow regimes. Biotechnol Bioeng 89(7):766-774
    • (2005) Biotechnol Bioeng , vol.89 , Issue.7 , pp. 766-774
    • Curran, S.J.1    Black, R.A.2
  • 44
    • 10044290683 scopus 로고    scopus 로고
    • A novel rotating-shaft bioreactor for two-phase cultivation of tissue-engineered cartilage
    • Chen H-C, Lee H-P, Sung M-L, Liao C-J, Hu Y-Cr(2004) A novel rotating-shaft bioreactor for two-phase cultivation of tissue-engineered cartilage. Biotechnol Prog 20:1802-1809
    • (2004) Biotechnol Prog , vol.20 , pp. 1802-1809
    • Chen, H.-C.1    Lee, H.-P.2    Sung, M.-L.3    Liao, C.-J.4    Hu, Y.-C.5
  • 48
    • 4544315734 scopus 로고    scopus 로고
    • Design and hydrodynamic evaluation of a novel pulsatile bioreactor for biologically active heart valves
    • Hildebrand DK, Wu ZJJ, Mayer JE, Sacks MS (2004) Design and hydrodynamic evaluation of a novel pulsatile bioreactor for biologically active heart valves. Ann Biomed Eng 32:1039-1049
    • (2004) Ann Biomed Eng , vol.32 , pp. 1039-1049
    • Hildebrand, D.K.1    Wu, Z.J.J.2    Mayer, J.E.3    Sacks, M.S.4
  • 50
    • 27644439603 scopus 로고    scopus 로고
    • Hydrostatic pressure/perfusion culture system designed and validated for tissue engineering
    • Watanabe S, Inagaki S, Kinouchi I, Takai H, Masuda Y, Mizuno S (2005) Hydrostatic pressure/perfusion culture system designed and validated for tissue engineering. J Biosci Bioeng 100(1):105-111
    • (2005) J Biosci Bioeng , vol.100 , Issue.1 , pp. 105-111
    • Watanabe, S.1    Inagaki, S.2    Kinouchi, I.3    Takai, H.4    Masuda, Y.5    Mizuno, S.6
  • 51
    • 33747122380 scopus 로고    scopus 로고
    • A fluid dynamics approach to bioreactor design for cell and tissue culture
    • Dusting J, Sheridan J, Hourigan K (2006) A fluid dynamics approach to bioreactor design for cell and tissue culture. Biotechnol Bioeng 94(6):1196-1208
    • (2006) Biotechnol Bioeng , vol.94 , Issue.6 , pp. 1196-1208
    • Dusting, J.1    Sheridan, J.2    Hourigan, K.3
  • 53
    • 34249815201 scopus 로고    scopus 로고
    • Characterization of the localized hydrodynamic shear forces and dissolved oxygen distribution in sparged bioreactors
    • Koynov A, Tryggvason G, Khinast JG (2007) Characterization of the localized hydrodynamic shear forces and dissolved oxygen distribution in sparged bioreactors. Biotechnol Bioeng 97(2):317-331
    • (2007) Biotechnol Bioeng , vol.97 , Issue.2 , pp. 317-331
    • Koynov, A.1    Tryggvason, G.2    Khinast, J.G.3
  • 54
    • 0001489148 scopus 로고
    • Memoire sur les lois du mouvement des fluids.
    • Navier CLMH (1822) Memoire sur les lois du mouvement des fluids. Mem. Acad. Sci. Inst. France 6: 389-440
    • (1822) Mem. Acad. Sci. Inst. France , vol.6 , pp. 389-440
    • Navier, C.L.M.H.1
  • 55
    • 0000119455 scopus 로고
    • On the theories of the internal friction of fluids in motion, and of the equilibrium and motion of elastic solids
    • Stokes GG (1845) On the theories of the internal friction of fluids in motion, and of the equilibrium and motion of elastic solids. Transactions of the Cambridge Philosophical Society Vol VIII, p287
    • (1845) Transactions of the Cambridge Philosophical Society , vol.8 , pp. 287
    • Stokes, G.G.1
  • 56
    • 84899663020 scopus 로고    scopus 로고
    • Stokes GG (1880) Mathematical and Physical Papers (reprinted from the original journals and transactions, with additional notes by the author). Cambridge at the university press, I, p75-129
    • Stokes GG (1880) Mathematical and Physical Papers (reprinted from the original journals and transactions, with additional notes by the author). Cambridge at the university press, Vol I, p75-129
  • 57
    • 0016462499 scopus 로고
    • 2nd Edition, McGraw-Hill, New York, p
    • Hinze JO (1975) Turbulence. 2nd Edition, McGraw-Hill, New York, p537-566
    • (1975) Turbulence , pp. 537-566
    • Hinze, J.O.1
  • 58
    • 84899660899 scopus 로고    scopus 로고
    • Darcy HPG (1856) Les fontaines publiques de la ville de Dijon. Dalmont, Paris (647p)
    • Darcy HPG (1856) Les fontaines publiques de la ville de Dijon. Dalmont, Paris (647p)
  • 59
    • 0042486028 scopus 로고
    • Description d'une machine pour mesurer la vitesse des eaux et la sillage des vaisseaux
    • Paris
    • De Pitot H (1732) Description d'une machine pour mesurer la vitesse des eaux et la sillage des vaisseaux. Memoires de l'Academie des Sciences, Paris
    • (1732) Memoires de l'Academie des Sciences
    • De Pitot, H.1
  • 60
    • 84899661398 scopus 로고    scopus 로고
    • Prandtl L (1942) Führer durch die Strömungslehre. 1. Auflage Verlag Vieweg & Sohn, Braunschweig
    • Prandtl L (1942) Führer durch die Strömungslehre. 1. Auflage Verlag Vieweg & Sohn, Braunschweig
  • 61
    • 84899664675 scopus 로고    scopus 로고
    • Prandtl L, Oertel H jr (2002) Kapitel 4: Dynamik der Flüssigkeiten und Gase, p57-176 in: Prandtl - Führer durch die Strömungslehre. Grundlagen und Phänomene. 11. überarbeitete und erweiterte Auflage, Herausgeber Oertel H jr., Verlag Vieweg, Braunschweig
    • Prandtl L, Oertel H jr (2002) Kapitel 4: Dynamik der Flüssigkeiten und Gase, p57-176 in: Prandtl - Führer durch die Strömungslehre. Grundlagen und Phänomene. 11. überarbeitete und erweiterte Auflage, Herausgeber Oertel H jr., Verlag Vieweg, Braunschweig


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