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Volumn 18, Issue 35, 2012, Pages 5645-5658

Pharmacological Innovations for posttraumatic stress disorder and medication-enhanced psychotherapy

Author keywords

Adrenergic beta antagonists; Anti anxiety agents; Antidepressants; Corticotropinreleasing hormone; Glucocorticoids; Memory; Psychotherapy; PTSD

Indexed keywords

3,4 METHYLENEDIOXYMETHAMPHETAMINE; 4 AMINOBUTYRIC ACID; APREPITANT; CARVEDILOL; CYCLOSERINE; DIAZEPAM; DOPAMINE; ENDOCANNABINOID; ESZOPICLONE; GLUTAMIC ACID; HYDROCORTISONE; METHYLENE BLUE; MIFEPRISTONE; NEPICASTAT; NEUROKININ; NEUROSTEROID; OMEGA 3 FATTY ACID; ORVEPITANT; OXYTOCIN; PRAZOSIN; PREDNISONE; PREGNENOLONE; PROPRANOLOL; PRX 03140; RAPAMYCIN; SUBSTANCE P; UNCLASSIFIED DRUG; UNINDEXED DRUG; VERUCERFONT; VOFOPITANT; YOHIMBINE;

EID: 84866534160     PISSN: 13816128     EISSN: 18734286     Source Type: Journal    
DOI: 10.2174/138161212803530899     Document Type: Review
Times cited : (40)

References (160)
  • 1
    • 20344374645 scopus 로고    scopus 로고
    • Prevalence, severity, and comorbidity of 12-month DSM-IV disorders in the National Comorbidity Survey Replication
    • Kessler RC, Chiu WT, Demler O, Merikangas KR, Walters EE. Prevalence, severity, and comorbidity of 12-month DSM-IV disorders in the National Comorbidity Survey Replication. Arch Gen Psychiatry 2005; 62: 617-27.
    • (2005) Arch Gen Psychiatry , vol.62 , pp. 617-627
    • Kessler, R.C.1    Chiu, W.T.2    Demler, O.3    Merikangas, K.R.4    Walters, E.E.5
  • 3
    • 22044441228 scopus 로고    scopus 로고
    • Anxiety disorders associated with suicidal ideation and suicide attempts in the National Comorbidity Survey
    • Sareen J, Houlahan T, Cox B, Asmundson GJG. Anxiety disorders associated with suicidal ideation and suicide attempts in the National Comorbidity Survey. J Nerv Ment Dis 2005; 193: 450-4.
    • (2005) J Nerv Ment Dis , vol.193 , pp. 450-454
    • Sareen, J.1    Houlahan, T.2    Cox, B.3    Asmundson, G.J.G.4
  • 4
    • 34247483139 scopus 로고    scopus 로고
    • Physical and mental comorbidity, disability, and suicidal behavior associated with posttraumatic stress disorder in a large community sample
    • Sareen J, Cox BJ, Stein MB, Afif TO, Fleet C, Asmundson GJG. Physical and mental comorbidity, disability, and suicidal behavior associated with posttraumatic stress disorder in a large community sample. Psychosom Med 2007; 69: 242-8.
    • (2007) Psychosom Med , vol.69 , pp. 242-248
    • Sareen, J.1    Cox, B.J.2    Stein, M.B.3    Afif, T.O.4    Fleet, C.5    Asmundson, G.J.G.6
  • 5
    • 33645498911 scopus 로고    scopus 로고
    • Pharmacotherapy for post traumatic stress disorder (PTSD)
    • Stein DJ, Ipser JC, Seedat S. Pharmacotherapy for post traumatic stress disorder (PTSD).Cochrane DB Syst Rev 2006; (1):CD002795.
    • (2006) Cochrane DB Syst Rev , Issue.1
    • Stein, D.J.1    Ipser, J.C.2    Seedat, S.3
  • 7
    • 60249085505 scopus 로고    scopus 로고
    • Pharmacologic alternatives to antidepressants in posttraumatic stress disorder: A systematic review
    • Berger W, Mendlowicz MV, Marques-Portella C, et al. Pharmacologic alternatives to antidepressants in posttraumatic stress disorder: A systematic review. Prog Neuropsychopharm Biol Psychiatry 2009; 33: 169-80.
    • (2009) Prog Neuropsychopharm Biol Psychiatry , vol.33 , pp. 169-180
    • Berger, W.1    Mendlowicz, M.V.2    Marques-Portella, C.3
  • 8
    • 0037315260 scopus 로고    scopus 로고
    • Reduction of nightmares and other PTSD symptoms in combat veterans by prazosin: A placebo-controlled study
    • Raskind MA, Peskind ER, Kanter ED, et al. Reduction of nightmares and other PTSD symptoms in combat veterans by prazosin: A placebo-controlled study. Am J Psychiatry 2003; 160: 371-3.
    • (2003) Am J Psychiatry , vol.160 , pp. 371-373
    • Raskind, M.A.1    Peskind, E.R.2    Kanter, E.D.3
  • 9
    • 33947587104 scopus 로고    scopus 로고
    • A parallel group placebo controlled study of prazosin for trauma nightmares and sleep disturbance in combat veterans with posttraumatic stress disorder
    • Raskind MA, Peskind ER, Hoff DJ, et al. A parallel group placebo controlled study of prazosin for trauma nightmares and sleep disturbance in combat veterans with posttraumatic stress disorder. Biol Psychiatry 2007; 61: 928-34.
    • (2007) Biol Psychiatry , vol.61 , pp. 928-934
    • Raskind, M.A.1    Peskind, E.R.2    Hoff, D.J.3
  • 10
    • 39449113662 scopus 로고    scopus 로고
    • Prazosin effects on objective sleep measures and clinical symptoms in civilian trauma posttraumatic stress disorder: A placebo-controlled study
    • Taylor FB, Martin P, Thompson C, et al. Prazosin effects on objective sleep measures and clinical symptoms in civilian trauma posttraumatic stress disorder: A placebo-controlled study. Biol Psychiatry 2008; 63; 629-32.
    • (2008) Biol Psychiatry , vol.63 , pp. 629-632
    • Taylor, F.B.1    Martin, P.2    Thompson, C.3
  • 11
    • 79960728972 scopus 로고    scopus 로고
    • Eszopiclone for the treatment of posttraumatic stress disorder and associated insomnia: A randomized, double-blind, placebo-controlled trial
    • Pollack MH, Hoge EA, Worthington JJ, et al. Eszopiclone for the treatment of posttraumatic stress disorder and associated insomnia: A randomized, double-blind, placebo-controlled trial. J Clin Psychiatry 2011; 72: 892-7.
    • (2011) J Clin Psychiatry , vol.72 , pp. 892-897
    • Pollack, M.H.1    Hoge, E.A.2    Worthington, J.J.3
  • 13
    • 79961040968 scopus 로고    scopus 로고
    • Adjunctive risperidone treatment for antidepressant-resistant symptoms of chronic military service-related PTSD
    • Krystal JH, Rosenheck RA, Cramer JA. Adjunctive risperidone treatment for antidepressant-resistant symptoms of chronic military service-related PTSD. JAMA 2011; 306: 493-502.
    • (2011) JAMA , vol.306 , pp. 493-502
    • Krystal, J.H.1    Rosenheck, R.A.2    Cramer, J.A.3
  • 15
    • 67651216043 scopus 로고    scopus 로고
    • Risk of lipid abnormality with haloperidol, olanzapine, quetiapine and risperidone in a Veterans Affairs population
    • Duncan EJ, Woolson, SL, Hamer RM, Dunlop BW. Risk of lipid abnormality with haloperidol, olanzapine, quetiapine and risperidone in a Veterans Affairs population. Int Clin Psychopharmacol 2009; 24:204-13.
    • (2009) Int Clin Psychopharmacol , vol.24 , pp. 204-213
    • Duncan, E.J.1    Woolson, S.L.2    Hamer, R.M.3    Dunlop, B.W.4
  • 16
    • 38349128467 scopus 로고    scopus 로고
    • Divalproex in the treatment of posttraumatic stress disorder: A randomized, double-blind, placebo-controlled trial in a veteran population
    • Davis LL, Davidson JRT, Ward LC, Bartolucci A., Bowden CL, Petty F. Divalproex in the treatment of posttraumatic stress disorder: A randomized, double-blind, placebo-controlled trial in a veteran population. J Clin Psychopharmcol 2008; 28: 84-8.
    • (2008) J Clin Psychopharmcol , vol.28 , pp. 84-88
    • Davis, L.L.1    Davidson, J.R.T.2    Ward, L.C.3    Bartolucci, A.4    Bowden, C.L.5    Petty, F.6
  • 17
    • 33847679030 scopus 로고    scopus 로고
    • Efficacy and safety of topiramate monotherapy in civilian posttraumatic stress disorder: A randomized, double-blind, placebo-controlled study
    • Tucker P, Trautman RP, Wyatt DB, et al. Efficacy and safety of topiramate monotherapy in civilian posttraumatic stress disorder: a randomized, double-blind, placebo-controlled study. J Clin Psychiatry 2007; 68: 201-6.
    • (2007) J Clin Psychiatry , vol.68 , pp. 201-206
    • Tucker, P.1    Trautman, R.P.2    Wyatt, D.B.3
  • 18
    • 0033135984 scopus 로고    scopus 로고
    • A preliminary study of lamotrigine for the treatment of posttraumatic stress disorder
    • Hertzberg MA, Butterfield MI, Feldman ME, et al. A preliminary study of lamotrigine for the treatment of posttraumatic stress disorder. Biol Psychiatry 1999; 45: 1226-9.
    • (1999) Biol Psychiatry , vol.45 , pp. 1226-1229
    • Hertzberg, M.A.1    Butterfield, M.I.2    Feldman, M.E.3
  • 19
    • 78649650201 scopus 로고    scopus 로고
    • Glutamate receptors in extinction and extinction-based therapies for psychiatric illness
    • Myers KM, Carlezon WA, Davis M. Glutamate receptors in extinction and extinction-based therapies for psychiatric illness. Neuropsychopharmacology Rev 2011; 36:274-93.
    • (2011) Neuropsychopharmacology Rev , vol.36 , pp. 274-293
    • Myers, K.M.1    Carlezon, W.A.2    Davis, M.3
  • 20
    • 72049085534 scopus 로고    scopus 로고
    • The neurocircuitry of fear, stress and anxiety disorders
    • Shin LM, Liberzon I. The neurocircuitry of fear, stress and anxiety disorders. Neuropsychopharmacology 2010; 35: 169-91.
    • (2010) Neuropsychopharmacology , vol.35 , pp. 169-191
    • Shin, L.M.1    Liberzon, I.2
  • 21
    • 35748963237 scopus 로고    scopus 로고
    • Functional neuroimaging of anxiety: A meta-analysis of emotional processing in PTSD, social anxiety disorder, and social phobia
    • Etkin, A., Wager, T.D. Functional neuroimaging of anxiety: A meta-analysis of emotional processing in PTSD, social anxiety disorder, and social phobia. Am J Psychiatry 2007; 164, 1476-88.
    • (2007) Am J Psychiatry , vol.164 , pp. 1476-1488
    • Etkin, A.1    Wager, T.D.2
  • 22
    • 66749120702 scopus 로고    scopus 로고
    • A discrete GABAergic relay mediates medial prefrontal cortical inhibition of the neuroendocrine stress response
    • Radley JJ, Gosseline KL, Sawchenko PE. A discrete GABAergic relay mediates medial prefrontal cortical inhibition of the neuroendocrine stress response. J Neurosci 2009; 29: 7330-40.
    • (2009) J Neurosci , vol.29 , pp. 7330-7340
    • Radley, J.J.1    Gosseline, K.L.2    Sawchenko, P.E.3
  • 23
    • 0032032326 scopus 로고    scopus 로고
    • Potent excitatory influence of prefrontal cortex activity on noradrenergic locus ceruleus neurons
    • Jodoj E, Chiang C, Aston-Jones C. Potent excitatory influence of prefrontal cortex activity on noradrenergic locus ceruleus neurons. Neuroscience 1998; 83: 63-79.
    • (1998) Neuroscience , vol.83 , pp. 63-79
    • Jodoj, E.1    Chiang, C.2    Aston-Jones, C.3
  • 24
    • 3242738309 scopus 로고    scopus 로고
    • Brain circuits involved in corticotropin-releasing factor-norepinephrine interactions during stress
    • Dunn AJ, Swiergiel AH, Palamarchouk V. Brain circuits involved in corticotropin-releasing factor-norepinephrine interactions during stress. Ann NY Acad Sci 2004; 1018: 25-34.
    • (2004) Ann NY Acad Sci , vol.1018 , pp. 25-34
    • Dunn, A.J.1    Swiergiel, A.H.2    Palamarchouk, V.3
  • 25
    • 84856068779 scopus 로고    scopus 로고
    • Corticotropin-releasing factor and noradrenergic signaling exert reciprocal control over startle reactivity
    • Gresack JE, Risbrough VB. Corticotropin-releasing factor and noradrenergic signaling exert reciprocal control over startle reactivity. Int J Neuropsychopharmacol 2011; 14: 1179-94.
    • (2011) Int J Neuropsychopharmacol , vol.14 , pp. 1179-1194
    • Gresack, J.E.1    Risbrough, V.B.2
  • 26
    • 0034533286 scopus 로고    scopus 로고
    • Cerebrospinal fluid corticotropin-releasing hormone in healthy humans: Effects of yohimbine and naloxone
    • Vythilingam M, Anderson GM, Owens MH, et al. Cerebrospinal fluid corticotropin-releasing hormone in healthy humans: effects of yohimbine and naloxone. J Clin Endocrinol Metab 2000; 85: 4138-45.
    • (2000) J Clin Endocrinol Metab , vol.85 , pp. 4138-4145
    • Vythilingam, M.1    Anderson, G.M.2    Owens, M.H.3
  • 27
    • 33746417478 scopus 로고    scopus 로고
    • Predicting PTSD prospectively based on prior trauma history and immediate biological responses
    • Delahanty DL, Nugent NR. Predicting PTSD prospectively based on prior trauma history and immediate biological responses. Ann NY Acad Sci 2006; 1071:27-40.
    • (2006) Ann NY Acad Sci , vol.1071 , pp. 27-40
    • Delahanty, D.L.1    Nugent, N.R.2
  • 28
    • 41849123044 scopus 로고    scopus 로고
    • Effects of traumarelated audiovisual stimulation on cerebrospinal fluid norepinephrine and corticotropin-releasing hormone concentrations in posttraumatic stress disorder
    • Geracioti TD Jr, Baker DG, Kasckow JW, et al. Effects of traumarelated audiovisual stimulation on cerebrospinal fluid norepinephrine and corticotropin-releasing hormone concentrations in posttraumatic stress disorder. Psychoneuroendocrinology 2008; 33: 416-24.
    • (2008) Psychoneuroendocrinology , vol.33 , pp. 416-424
    • Geracioti Jr., T.D.1    Baker, D.G.2    Kasckow, J.W.3
  • 29
    • 0142188601 scopus 로고    scopus 로고
    • Immediate treatment with propranolol decreases posttraumatic stress disorder two months after trauma
    • Vaiva G, Ducrocq F, Jezequel K, et al. Immediate treatment with propranolol decreases posttraumatic stress disorder two months after trauma. Biol Psychiatry 2003, 54: 947-9.
    • (2003) Biol Psychiatry , vol.54 , pp. 947-949
    • Vaiva, G.1    Ducrocq, F.2    Jezequel, K.3
  • 30
    • 0442272538 scopus 로고    scopus 로고
    • When not enough is too much: The role of insufficient glucocorticoid signaling in the pathophysiology of stress-related disorders
    • Raison CL, Miller AH. When not enough is too much: the role of insufficient glucocorticoid signaling in the pathophysiology of stress-related disorders. Am J Psychiatry 2003; 160: 1554-65.
    • (2003) Am J Psychiatry , vol.160 , pp. 1554-1565
    • Raison, C.L.1    Miller, A.H.2
  • 31
    • 0028921409 scopus 로고
    • Stress-induced norepinephrine release in the hypothalamic paraventricular nucleus and pituitary-adrenocortical and sympathoadrenal activity: In vivo microdialysis studies
    • Pacak K, Palkovits M, Kopin IJ, Goldstein DS. Stress-induced norepinephrine release in the hypothalamic paraventricular nucleus and pituitary-adrenocortical and sympathoadrenal activity: in vivo microdialysis studies. Front Neuroendocrinol 1995; 16: 89-150.
    • (1995) Front Neuroendocrinol , vol.16 , pp. 89-150
    • Pacak, K.1    Palkovits, M.2    Kopin, I.J.3    Goldstein, D.S.4
  • 32
    • 33746851204 scopus 로고    scopus 로고
    • Assessment of HPA-axis function in posttraumatic stress disorder: Pharmacological and non-pharmacological challenge tests, a review
    • de Kloet CS, Vermetten E, Geuze E, Kavelaars A, Heijnen CJ, Westenberg HG. Assessment of HPA-axis function in posttraumatic stress disorder: pharmacological and non-pharmacological challenge tests, a review. J Psychiat Res 2006; 40: 550-67.
    • (2006) J Psychiat Res , vol.40 , pp. 550-567
    • de Kloet, C.S.1    Vermetten, E.2    Geuze, E.3    Kavelaars, A.4    Heijnen, C.J.5    Westenberg, H.G.6
  • 33
    • 84855939928 scopus 로고    scopus 로고
    • Gene x environment vulnerability factors for PTSD: The HPA axis
    • Mehta D, Binder E. Gene x environment vulnerability factors for PTSD: the HPA axis. Neuropharmacology 2012; 62: 654-62.
    • (2012) Neuropharmacology , vol.62 , pp. 654-662
    • Mehta, D.1    Binder, E.2
  • 35
    • 42049122131 scopus 로고    scopus 로고
    • A second look at prior trauma and the posttraumatic stress disorder effects of subsequent trauma: A prospective epidemiologic study
    • Breslau N, Peterson EL, Schultz LR. A second look at prior trauma and the posttraumatic stress disorder effects of subsequent trauma: A prospective epidemiologic study. Arch Gen Psychiatry 2008; 65: 431-7.
    • (2008) Arch Gen Psychiatry , vol.65 , pp. 431-437
    • Breslau, N.1    Peterson, E.L.2    Schultz, L.R.3
  • 36
    • 0024322451 scopus 로고
    • Post-traumatic stress disorder, hormones and memory
    • Pitman RK. Post-traumatic stress disorder, hormones and memory. Biol Psychiatry 1989; 26: 221-3.
    • (1989) Biol Psychiatry , vol.26 , pp. 221-223
    • Pitman, R.K.1
  • 37
    • 38049049257 scopus 로고    scopus 로고
    • Pharmacotherapy to prevent PTSD: Results from a randomized controlled proof-of- concept trial in physically injured patients
    • Stein MB, Kerridge C, Dimsdale JE, Hoyt DB. Pharmacotherapy to prevent PTSD: Results from a randomized controlled proof-of- concept trial in physically injured patients. J Traumatic Stress 2007; 20: 923-32.
    • (2007) J Traumatic Stress , vol.20 , pp. 923-932
    • Stein, M.B.1    Kerridge, C.2    Dimsdale, J.E.3    Hoyt, D.B.4
  • 38
    • 84863049769 scopus 로고    scopus 로고
    • Effect of acute posttrauma propranolol on PTSD outcome and physiological responses during script-driven imagery
    • Hoge EA, Worthington JJ, Nagurney JT, et al. Effect of acute posttrauma propranolol on PTSD outcome and physiological responses during script-driven imagery. CNS Neurosci Ther 2012; 18(1): 21-7.
    • (2012) CNS Neurosci Ther , vol.18 , Issue.1 , pp. 21-27
    • Hoge, E.A.1    Worthington, J.J.2    Nagurney, J.T.3
  • 39
    • 77954959068 scopus 로고    scopus 로고
    • Associations of cortisol with posttraumatic stress symptoms and negative life events: A study of police officers and firefighters
    • Witteveen AB, Huizink AC, Slottje P, et al. Associations of cortisol with posttraumatic stress symptoms and negative life events: a study of police officers and firefighters. Psychoneuroenocrinology 2010; 35: 1113-8.
    • (2010) Psychoneuroenocrinology , vol.35 , pp. 1113-1118
    • Witteveen, A.B.1    Huizink, A.C.2    Slottje, P.3
  • 41
    • 0033561925 scopus 로고    scopus 로고
    • Developmental traumatology. Part I: Biological stress systems
    • A.E. Bennett Research Award
    • De Bellis MD, Baum AS, Birmaher B, et al. A.E. Bennett Research Award. Developmental traumatology. Part I: Biological stress systems. Biol Psychiatry 1999; 45: 1259-70.
    • (1999) Biol Psychiatry , vol.45 , pp. 1259-1270
    • de Bellis, M.D.1    Baum, A.S.2    Birmaher, B.3
  • 42
    • 4744340780 scopus 로고    scopus 로고
    • Initial urinary epinephrine and cortisol levels predict acute PTSD symptoms in child trauma victims
    • Delahanty DL, Nugent NR, Christopher NC, Walsh M. Initial urinary epinephrine and cortisol levels predict acute PTSD symptoms in child trauma victims. Psychoneuroendocrinology 2005; 30: 121-8.
    • (2005) Psychoneuroendocrinology , vol.30 , pp. 121-128
    • Delahanty, D.L.1    Nugent, N.R.2    Christopher, N.C.3    Walsh, M.4
  • 43
    • 0036530044 scopus 로고    scopus 로고
    • Role of adrenal stress hormones in forming lasting memories in the brain
    • McGaugh JL, Roozendaal B. Role of adrenal stress hormones in forming lasting memories in the brain. Curr Op Neurobiol 2002; 12: 205-10.
    • (2002) Curr Op Neurobiol , vol.12 , pp. 205-210
    • McGaugh, J.L.1    Roozendaal, B.2
  • 44
    • 12144287939 scopus 로고    scopus 로고
    • Stress doses of hydrocortisone, traumatic memories and symptoms of posttraumatic stress disorder in patients after cardiac surgery: A randomized study
    • Schelling G, Kilger E, Roozendaal B, et al. Stress doses of hydrocortisone, traumatic memories and symptoms of posttraumatic stress disorder in patients after cardiac surgery: A randomized study. Biol Psychiatry 2004; 55: 627-33.
    • (2004) Biol Psychiatry , vol.55 , pp. 627-633
    • Schelling, G.1    Kilger, E.2    Roozendaal, B.3
  • 45
    • 31044448794 scopus 로고    scopus 로고
    • Stress doses of hydrocortisone reduce chronic stress symptoms and improve health related quality of life in high-risk patients after cardiac surgery: A randomized study
    • Weis F, Kilger E, Roozendaal B, et al. Stress doses of hydrocortisone reduce chronic stress symptoms and improve health related quality of life in high-risk patients after cardiac surgery: a randomized study. J Thorac Cardiovas Surg 2006; 131: 277-82.
    • (2006) J Thorac Cardiovas Surg , vol.131 , pp. 277-282
    • Weis, F.1    Kilger, E.2    Roozendaal, B.3
  • 46
    • 80053386486 scopus 로고    scopus 로고
    • High dose hydrocortisone immediately after trauma may alter the trajectory of PTSD: Interplay between clinical and animal studies
    • Zohar J, Yahalom H, Kozlovsky N, et al. High dose hydrocortisone immediately after trauma may alter the trajectory of PTSD: Interplay between clinical and animal studies. Eur Neurospyschopharmacol 2011; 21: 796-809.
    • (2011) Eur Neurospyschopharmacol , vol.21 , pp. 796-809
    • Zohar, J.1    Yahalom, H.2    Kozlovsky, N.3
  • 47
    • 77957107113 scopus 로고    scopus 로고
    • CRF receptor blockade prevents initiation and consolidation of stress effects on affect in the predator stress model of PTSD
    • Adamec R, Fougere D, Risbrough V. CRF receptor blockade prevents initiation and consolidation of stress effects on affect in the predator stress model of PTSD. Int J Neuropsychopharmacol 2010; 13: 747-57.
    • (2010) Int J Neuropsychopharmacol , vol.13 , pp. 747-757
    • Adamec, R.1    Fougere, D.2    Risbrough, V.3
  • 48
    • 0036458043 scopus 로고    scopus 로고
    • Glucocorticoids interact with the basolateral amygdala -adrenoreceptor-cAMP/cAMP/PKA system in influencing memory consolidation
    • Roozendaal B, Quirarte GL, McGaugh JL. Glucocorticoids interact with the basolateral amygdala -adrenoreceptor-cAMP/cAMP/PKA system in influencing memory consolidation. Eur J Neurosci 2002; 12: 553-60.
    • (2002) Eur J Neurosci , vol.12 , pp. 553-560
    • Roozendaal, B.1    Quirarte, G.L.2    McGaugh, J.L.3
  • 49
    • 52949115286 scopus 로고    scopus 로고
    • Early poststressor intervention with high-dose corticosterone attenuates posttraumatic stress responses in an animal model of posttraumatic stress disorder
    • Cohen H, Matar MA, Buskila D, Kaplan Z, Zohar J. Early poststressor intervention with high-dose corticosterone attenuates posttraumatic stress responses in an animal model of posttraumatic stress disorder. Biol Psychiatry, 2008; 64: 708-17.
    • (2008) Biol Psychiatry , vol.64 , pp. 708-717
    • Cohen, H.1    Matar, M.A.2    Buskila, D.3    Kaplan, Z.4    Zohar, J.5
  • 50
    • 77649237004 scopus 로고    scopus 로고
    • Behavioral effects of neuropeptides in rodent models of depression and anxiety
    • Rotzinger S, Lovejoy DA, Tan LA. Behavioral effects of neuropeptides in rodent models of depression and anxiety. Peptides 2010; 31: 736-56.
    • (2010) Peptides , vol.31 , pp. 736-756
    • Rotzinger, S.1    Lovejoy, D.A.2    Tan, L.A.3
  • 51
    • 78149470894 scopus 로고    scopus 로고
    • Oxytocin reduces background anxiety in a fear-potentiated startle paradigm
    • Missig G, Ayers LW, Schulkin J, Rosen JB. Oxytocin reduces background anxiety in a fear-potentiated startle paradigm. Neuropsychopharmacology 2010; 35: 2607-16.
    • (2010) Neuropsychopharmacology , vol.35 , pp. 2607-2616
    • Missig, G.1    Ayers, L.W.2    Schulkin, J.3    Rosen, J.B.4
  • 52
    • 0347627798 scopus 로고    scopus 로고
    • Social support and oxytocin interact to suppress cortisol and subjective responses to psychosocial stress
    • Heinrichs M, Baumgartner T, Kirschbaum C, Ehlert U. Social support and oxytocin interact to suppress cortisol and subjective responses to psychosocial stress. Biol Psychiatry 2003; 54: 1389-98.
    • (2003) Biol Psychiatry , vol.54 , pp. 1389-1398
    • Heinrichs, M.1    Baumgartner, T.2    Kirschbaum, C.3    Ehlert, U.4
  • 53
    • 48549089869 scopus 로고    scopus 로고
    • Oxytocin attenuates affective evaluations of conditioned faces and amygdala activity
    • Petrovic P, Kalisch R, Singer T, Dolan RJ. Oxytocin attenuates affective evaluations of conditioned faces and amygdala activity. J Neurosci 2008; 28: 6607-15.
    • (2008) J Neurosci , vol.28 , pp. 6607-6615
    • Petrovic, P.1    Kalisch, R.2    Singer, T.3    Dolan, R.J.4
  • 54
    • 0027255584 scopus 로고
    • Effects of intranasal vasopressin and oxytocin on physiologic responding during personal combat imagery in Vietnam veterans with posttraumatic stress disorder
    • Pitman RK, Orr SP, Lasko NB. Effects of intranasal vasopressin and oxytocin on physiologic responding during personal combat imagery in Vietnam veterans with posttraumatic stress disorder. Psychiatry Res 1993; 48: 107-17.
    • (1993) Psychiatry Res , vol.48 , pp. 107-117
    • Pitman, R.K.1    Orr, S.P.2    Lasko, N.B.3
  • 55
    • 47649083963 scopus 로고    scopus 로고
    • Impact of prosocial neuropeptides on human brain function
    • Meyer-Lindenberg A. Impact of prosocial neuropeptides on human brain function. Prog Brain Res. 2008; 170: 463-70.
    • (2008) Prog Brain Res , vol.170 , pp. 463-470
    • Meyer-Lindenberg, A.1
  • 57
    • 77956123825 scopus 로고    scopus 로고
    • A psychobiological rationale for oxytocin in the treatment of posttraumatic stress disorder
    • Olff M, Langeland W, Wiitteveen A, Denys D. A psychobiological rationale for oxytocin in the treatment of posttraumatic stress disorder. CNS Spectr 2010; 15: 522-30.
    • (2010) CNS Spectr , vol.15 , pp. 522-530
    • Olff, M.1    Langeland, W.2    Wiitteveen, A.3    Denys, D.4
  • 59
    • 77953611863 scopus 로고    scopus 로고
    • Behavioral and neural analysis of GABA in the acquisition, consolidation, reconsolidation and extinction of fear memory
    • Makkar SR, Zhang SQ, Cranney J. Behavioral and neural analysis of GABA in the acquisition, consolidation, reconsolidation and extinction of fear memory. Neuropyschopharmacology 2010; 35: 1625-52.
    • (2010) Neuropyschopharmacology , vol.35 , pp. 1625-1652
    • Makkar, S.R.1    Zhang, S.Q.2    Cranney, J.3
  • 60
    • 33746672582 scopus 로고    scopus 로고
    • Midazolam disrupts fear memory reconsolidation
    • Bustos SG, Maldonado H, Molina VA. Midazolam disrupts fear memory reconsolidation. Neuroscience 2006; 139: 831-42.
    • (2006) Neuroscience , vol.139 , pp. 831-842
    • Bustos, S.G.1    Maldonado, H.2    Molina, V.A.3
  • 61
    • 57049151363 scopus 로고    scopus 로고
    • The role of GABA and anxiety in the reconsolidation of conditioned fear
    • Zhang S, Cranney J. The role of GABA and anxiety in the reconsolidation of conditioned fear. Behav Neurosci 2008; 122: 1295-305.
    • (2008) Behav Neurosci , vol.122 , pp. 1295-1305
    • Zhang, S.1    Cranney, J.2
  • 62
    • 77952124303 scopus 로고    scopus 로고
    • Omega-3 fatty acids for secondary prevention of posttraumatic stress disorder after accidental injury: An open-label pilot study
    • Matsuoka Y, Nishi D, Yonemoto N, Hamazaki K, Hashimoto K, Hamazaki T. Omega-3 fatty acids for secondary prevention of posttraumatic stress disorder after accidental injury: an open-label pilot study. J Clin Psychopharmacol 2010; 30: 217-9.
    • (2010) J Clin Psychopharmacol , vol.30 , pp. 217-219
    • Matsuoka, Y.1    Nishi, D.2    Yonemoto, N.3    Hamazaki, K.4    Hashimoto, K.5    Hamazaki, T.6
  • 63
    • 33646138943 scopus 로고    scopus 로고
    • Docosahexaenoic acid promotes neurogenesis in vitro and in vivo
    • Kawakita E, Hashimoto M, Shido O. Docosahexaenoic acid promotes neurogenesis in vitro and in vivo. Neuroscience 2006, 139: 991-7.
    • (2006) Neuroscience , vol.139 , pp. 991-997
    • Kawakita, E.1    Hashimoto, M.2    Shido, O.3
  • 64
    • 49249104880 scopus 로고    scopus 로고
    • Docosahexaenoic acid dietary supplementation enhances the effects of exercise on synaptic plasticity and cognition
    • Wu A, Ying Z, Gomez-Pinilla F. Docosahexaenoic acid dietary supplementation enhances the effects of exercise on synaptic plasticity and cognition. Neuroscience 2008; 155: 751-9.
    • (2008) Neuroscience , vol.155 , pp. 751-759
    • Wu, A.1    Ying, Z.2    Gomez-Pinilla, F.3
  • 65
    • 70350771278 scopus 로고    scopus 로고
    • Adult neurogenesis modulates the hippocampus-dependent period of associative fear memory
    • Kitamura T, Saitoh Y, Takeshima N, et al. Adult neurogenesis modulates the hippocampus-dependent period of associative fear memory. Cell. 2009; 139: 814-27.
    • (2009) Cell , vol.139 , pp. 814-827
    • Kitamura, T.1    Saitoh, Y.2    Takeshima, N.3
  • 66
    • 74149095074 scopus 로고    scopus 로고
    • Morphine use after combat injury in Iraq and post-traumatic stress disorder
    • Holbrook TL, Galarneau MR, Quinn K, Doughterty AL. Morphine use after combat injury in Iraq and post-traumatic stress disorder. New Eng J Med 2010; 362: 110-7.
    • (2010) New Eng J Med , vol.362 , pp. 110-117
    • Holbrook, T.L.1    Galarneau, M.R.2    Quinn, K.3    Doughterty, A.L.4
  • 67
    • 59449084371 scopus 로고    scopus 로고
    • A study of the protective function of acute morphine administration on subsequent posttraumatic stress disorder
    • Bryant RA, Cremer M, O'Donnell M, Silove D, McFarlane AC. A study of the protective function of acute morphine administration on subsequent posttraumatic stress disorder. Biol Psychiatry 2009; 65: 438-40.
    • (2009) Biol Psychiatry , vol.65 , pp. 438-440
    • Bryant, R.A.1    Cremer, M.2    O'Donnell, M.3    Silove, D.4    McFarlane, A.C.5
  • 68
    • 33646683309 scopus 로고    scopus 로고
    • Reboxetine versus fluovoxamine in the treatment of motor vehicle accident-related posttraumatic stress disorder
    • Spivak B, Strous RD, Shaked G, Shabash E, Kotler M, Weizman A. Reboxetine versus fluovoxamine in the treatment of motor vehicle accident-related posttraumatic stress disorder. J Clin Psychopharmacol 2006; 26: 152-56.
    • (2006) J Clin Psychopharmacol , vol.26 , pp. 152-156
    • Spivak, B.1    Strous, R.D.2    Shaked, G.3    Shabash, E.4    Kotler, M.5    Weizman, A.6
  • 69
    • 84857061992 scopus 로고    scopus 로고
    • Noradrenergic vs serotonergic antidepressant with or without naltrexone for veterans with PTSD and comorbid alcohol dependence
    • Petrakis IL, Ralevski E, Desai N, et al. Noradrenergic vs serotonergic antidepressant with or without naltrexone for veterans with PTSD and comorbid alcohol dependence. Neuropsychopharmacology 2012; 37(4): 996-1004.
    • (2012) Neuropsychopharmacology , vol.37 , Issue.4 , pp. 996-1004
    • Petrakis, I.L.1    Ralevski, E.2    Desai, N.3
  • 70
  • 71
    • 33846321208 scopus 로고    scopus 로고
    • No improvement of posttraumatic stress disorder symptoms with guanfacine treatment
    • Neylan TC, Lenoci M, Samuelson KW, et al. No improvement of posttraumatic stress disorder symptoms with guanfacine treatment. Am J Psychiatry 2006; 163: 2186-8.
    • (2006) Am J Psychiatry , vol.163 , pp. 2186-2188
    • Neylan, T.C.1    Lenoci, M.2    Samuelson, K.W.3
  • 72
    • 8544268648 scopus 로고    scopus 로고
    • Catecholamine modulatory effects of nepicastat (RS-25560-197), a novel, potent and selective inhibitor of dopamine-hydroxylase
    • Stanley WC, Li B, Bonhaus DW. Catecholamine modulatory effects of nepicastat (RS-25560-197), a novel, potent and selective inhibitor of dopamine-hydroxylase. Br J Pharmacol 1997; 121: 1803-9.
    • (1997) Br J Pharmacol , vol.121 , pp. 1803-1809
    • Stanley, W.C.1    Li, B.2    Bonhaus, D.W.3
  • 73
    • 33847767095 scopus 로고    scopus 로고
    • The role of dopamine in the pathophysiology of depression
    • Dunlop BW, Nemeroff CB. The role of dopamine in the pathophysiology of depression. Arch Gen Psychiatry 2007; 64: 327-37.
    • (2007) Arch Gen Psychiatry , vol.64 , pp. 327-337
    • Dunlop, B.W.1    Nemeroff, C.B.2
  • 74
    • 3042561718 scopus 로고    scopus 로고
    • Pramipexole for bipolar II depression: A placebo-controlled proof of concept study
    • Zarate CA Jr, Payne JL, Singh J, et al. Pramipexole for bipolar II depression: a placebo-controlled proof of concept study. Biol Psychiatry 2004; 56: 54-60.
    • (2004) Biol Psychiatry , vol.56 , pp. 54-60
    • Zarate Jr., C.A.1    Payne, J.L.2    Singh, J.3
  • 75
    • 79957832489 scopus 로고    scopus 로고
    • 5-HT(4) receptor agonist mediated enhancement of cognitive function in vivo and amyloid precursor protein processing in vitro: A pharmacodynamic and pharmacokinetic assessment
    • Shen F, Smith JA, Chang R, et al. 5-HT(4) receptor agonist mediated enhancement of cognitive function in vivo and amyloid precursor protein processing in vitro: A pharmacodynamic and pharmacokinetic assessment. Neuropharmacology 2011; 61: 69-79.
    • (2011) Neuropharmacology , vol.61 , pp. 69-79
    • Shen, F.1    Smith, J.A.2    Chang, R.3
  • 77
    • 71849086986 scopus 로고    scopus 로고
    • Investigating the impact of sex and cortisol on implicit fear conditioning with fMRI
    • Merz CJ, Tabbert K, Schweckendiek J, et al. Investigating the impact of sex and cortisol on implicit fear conditioning with fMRI. Psychoneuroendocrinologylogy 2010; 35: 33-46.
    • (2010) Psychoneuroendocrinologylogy , vol.35 , pp. 33-46
    • Merz, C.J.1    Tabbert, K.2    Schweckendiek, J.3
  • 78
    • 3342984728 scopus 로고    scopus 로고
    • Low-dose cortisol for symptoms of posttraumatic stress disorder
    • Aerni A, Traber R, Hock C. Low-dose cortisol for symptoms of posttraumatic stress disorder. Am J Psychiatry 2004; 161: 1488-90.
    • (2004) Am J Psychiatry , vol.161 , pp. 1488-1490
    • Aerni, A.1    Traber, R.2    Hock, C.3
  • 79
    • 13844272192 scopus 로고    scopus 로고
    • Effects of oral cortisol treatment in healthy young women on memory retrieval of negative and neutral words
    • Kuhlmann S, Krischbaum C, Wolf OT. Effects of oral cortisol treatment in healthy young women on memory retrieval of negative and neutral words. Neurobiol Learn Mem 2005; 83: 158-62.
    • (2005) Neurobiol Learn Mem , vol.83 , pp. 158-162
    • Kuhlmann, S.1    Krischbaum, C.2    Wolf, O.T.3
  • 80
    • 79960576745 scopus 로고    scopus 로고
    • Hydrocortisone suppression of the fear-potentiated startle response and posttraumatic stress disorder
    • Miller MW, McKinney AE, Kanter FS, Korte KJ, Lovallo WR. Hydrocortisone suppression of the fear-potentiated startle response and posttraumatic stress disorder. Psychoneuroendocrinology 2011; 36: 970-80.
    • (2011) Psychoneuroendocrinology , vol.36 , pp. 970-980
    • Miller, M.W.1    McKinney, A.E.2    Kanter, F.S.3    Korte, K.J.4    Lovallo, W.R.5
  • 81
    • 0032751399 scopus 로고    scopus 로고
    • Corticotropin-releasing hormone receptor subtypes and emotion
    • Steckler T, Holsboer F. Corticotropin-releasing hormone receptor subtypes and emotion. Biol Psychiatry 1999; 46: 1480-508.
    • (1999) Biol Psychiatry , vol.46 , pp. 1480-1508
    • Steckler, T.1    Holsboer, F.2
  • 82
    • 0031004906 scopus 로고    scopus 로고
    • Elevated CSF corticotropinreleasing factor concentrations in posttraumatic stress disorder
    • Bremner J, Licinio J, Darness A, et al. Elevated CSF corticotropinreleasing factor concentrations in posttraumatic stress disorder. Am J Psychiatry 1997; 154: 624-9.
    • (1997) Am J Psychiatry , vol.154 , pp. 624-629
    • Bremner, J.1    Licinio, J.2    Darness, A.3
  • 83
    • 0346850971 scopus 로고    scopus 로고
    • Corticotropin-releasing factor in posttraumatic stress disorder (PTSD) with secondary psychotic symptoms, nonpsychotic PTSD, and healthy control subjects
    • Sautter F, Bissette G, Wiley J, et al. Corticotropin-releasing factor in posttraumatic stress disorder (PTSD) with secondary psychotic symptoms, nonpsychotic PTSD, and healthy control subjects. Biol Psychiatry 2003; 54: 1382-8.
    • (2003) Biol Psychiatry , vol.54 , pp. 1382-1388
    • Sautter, F.1    Bissette, G.2    Wiley, J.3
  • 84
    • 0032905877 scopus 로고    scopus 로고
    • Serial CSF corticotropinreleasing hormone levels and adrenocortical activity in combat veterans with posttraumatic stress disorder
    • Baker D, West S, Nicholson W, et al. Serial CSF corticotropinreleasing hormone levels and adrenocortical activity in combat veterans with posttraumatic stress disorder. Am J Psychiatry 1999; 156: 585-8.
    • (1999) Am J Psychiatry , vol.156 , pp. 585-588
    • Baker, D.1    West, S.2    Nicholson, W.3
  • 85
    • 0036137946 scopus 로고    scopus 로고
    • Mice deficient for both corticotropin-releasing factor receptor 1 (CRFR1) and CRFR2 have an impaired stress response and display sexually dichotomous anxiety-like behavior
    • Bale TL, Picetti R, Contarino A, Koob GF, Vale WW, Lee KF. Mice deficient for both corticotropin-releasing factor receptor 1 (CRFR1) and CRFR2 have an impaired stress response and display sexually dichotomous anxiety-like behavior. J Neurosci 2002; 22: 193-9.
    • (2002) J Neurosci , vol.22 , pp. 193-199
    • Bale, T.L.1    Picetti, R.2    Contarino, A.3    Koob, G.F.4    Vale, W.W.5    Lee, K.F.6
  • 87
    • 27744501266 scopus 로고    scopus 로고
    • Long-term consequences of neonatal rearing on central corticotropin-releasing factor systems in adult male rat offspring
    • Plotsky P, Thrivikraman K, Nemeroff C, Caldji C, Sharma S, Meaney M. Long-term consequences of neonatal rearing on central corticotropin-releasing factor systems in adult male rat offspring. Neuropsychopharmacology 2005; 30: 2192-204.
    • (2005) Neuropsychopharmacology , vol.30 , pp. 2192-2204
    • Plotsky, P.1    Thrivikraman, K.2    Nemeroff, C.3    Caldji, C.4    Sharma, S.5    Meaney, M.6
  • 88
    • 43349095568 scopus 로고    scopus 로고
    • The correlation between ketamine and posttraumatic stress disorder in burned service members
    • McGhee LL, Maani CV, Garza TH, Gaylord KM, Black IH. The correlation between ketamine and posttraumatic stress disorder in burned service members. J Trauma 2008; 64 (2 Suppl): S195-8.
    • (2008) J Trauma , vol.64 , Issue.2 SUPPL. , pp. 195-198
    • McGhee, L.L.1    Maani, C.V.2    Garza, T.H.3    Gaylord, K.M.4    Black, I.H.5
  • 89
    • 33644822593 scopus 로고    scopus 로고
    • Efficacy and tolerability of coaxil (tianeptine) in the therapy of posttraumatic stress disorder
    • Aleksandrovskii Iu A, Avedisova AS, Boev IV, et al. Efficacy and tolerability of coaxil (tianeptine) in the therapy of posttraumatic stress disorder. Zh Nevrol Psikhiatr Im S S Korsakova 2005; 105: 24-9.
    • (2005) Zh Nevrol Psikhiatr Im S S Korsakova , vol.105 , pp. 24-29
    • Aleksandrovskii, I.A.1    Avedisova, A.S.2    Boev, I.V.3
  • 90
    • 33646074019 scopus 로고    scopus 로고
    • A comparative study of fluoxetine, moclobemide, and tianeptine in the treatment of posttraumatic stress disorder following an earthquake
    • Onder E, Tural U, Aker T. A comparative study of fluoxetine, moclobemide, and tianeptine in the treatment of posttraumatic stress disorder following an earthquake. Eur Psychiatry 2006; 21: 174-9.
    • (2006) Eur Psychiatry , vol.21 , pp. 174-179
    • Onder, E.1    Tural, U.2    Aker, T.3
  • 91
    • 77249090207 scopus 로고    scopus 로고
    • The neurobiological properties of tianeptine (Stablon): From monoamine hypothesis to glutamatergic modulation
    • McEwen BS, Chattarji S, Diamond DM, et al. The neurobiological properties of tianeptine (Stablon): from monoamine hypothesis to glutamatergic modulation. Mol Psychiatry 2010; 15: 237-49.
    • (2010) Mol Psychiatry , vol.15 , pp. 237-249
    • McEwen, B.S.1    Chattarji, S.2    Diamond, D.M.3
  • 92
    • 0037293399 scopus 로고    scopus 로고
    • Neuroactive steroids: Mechanisms of action and neuropsychopharmacological properties
    • Rupprecht R. Neuroactive steroids: mechanisms of action and neuropsychopharmacological properties. Psychoneuroendocrinologylogy 2003; 28: 139-68.
    • (2003) Psychoneuroendocrinologylogy , vol.28 , pp. 139-168
    • Rupprecht, R.1
  • 93
    • 84870203684 scopus 로고    scopus 로고
    • Pharmacology of endogenous neuroactive steroids
    • Reddy DS. Pharmacology of endogenous neuroactive steroids. Crit Rev Neurobiol 2003; 21: 245-54.
    • (2003) Crit Rev Neurobiol , vol.21 , pp. 245-254
    • Reddy, D.S.1
  • 94
    • 84857024927 scopus 로고    scopus 로고
    • Neurosteroids and GABA-A receptor interactions: A focus on stress
    • Gunn BG, Brown AR, Lambert JJ, Belelli D. Neurosteroids and GABA-A receptor interactions: a focus on stress. Front Neurosci 2011; 5:131.
    • (2011) Front Neurosci , vol.5 , pp. 131
    • Gunn, B.G.1    Brown, A.R.2    Lambert, J.J.3    Belelli, D.4
  • 95
    • 78649361562 scopus 로고    scopus 로고
    • Neurosteroids: Endogenous role in the human brain and therapeutic potentials
    • Reddy DS. Neurosteroids: Endogenous role in the human brain and therapeutic potentials. Prog Brain Res 2010; 186: 113-37.
    • (2010) Prog Brain Res , vol.186 , pp. 113-137
    • Reddy, D.S.1
  • 97
    • 0037317122 scopus 로고    scopus 로고
    • Induced panic attacks shift -aminobutyric acid type A receptor modulatory neuroactive steroid composition in patients with panic disorder: Preliminary results
    • Strohle A, Romeo E, di Michele F, et al. Induced panic attacks shift -aminobutyric acid type A receptor modulatory neuroactive steroid composition in patients with panic disorder: preliminary results. Arch Gen Psychiatry 2003; 60: 161-8.
    • (2003) Arch Gen Psychiatry , vol.60 , pp. 161-168
    • Strohle, A.1    Romeo, E.2    di Michele, F.3
  • 98
    • 0028801074 scopus 로고
    • A putative receptor for neurosteroids on the GABAA receptor complex: The pharmacological properties and therapeutic potential of epalons
    • Gee KW, McCauley LD, Nan LC. A putative receptor for neurosteroids on the GABAA receptor complex: the pharmacological properties and therapeutic potential of epalons. Crit Rev Neurobiol 1995; 9: 207-27.
    • (1995) Crit Rev Neurobiol , vol.9 , pp. 207-227
    • Gee, K.W.1    McCauley, L.D.2    Nan, L.C.3
  • 99
    • 67651117272 scopus 로고    scopus 로고
    • Translocator protein (18 kD) as target for anxiolytics without benzodiazepine-like side effects
    • Rupprecht R, Rammes G, Eser D, et al. Translocator protein (18 kD) as target for anxiolytics without benzodiazepine-like side effects. Science 2009; 325 (5939):490-3.
    • (2009) Science , vol.325 , Issue.5939 , pp. 490-493
    • Rupprecht, R.1    Rammes, G.2    Eser, D.3
  • 100
    • 17844404803 scopus 로고    scopus 로고
    • Substance P receptor antagonists in psychiatry
    • Herpfer I, Lieb K. Substance P receptor antagonists in psychiatry. CNS Drugs 2005; 19: 275-93.
    • (2005) CNS Drugs , vol.19 , pp. 275-293
    • Herpfer, I.1    Lieb, K.2
  • 101
    • 33749556143 scopus 로고    scopus 로고
    • The role of substance P in stress and anxiety responses
    • Ebner K, Singewald N. The role of substance P in stress and anxiety responses. Amino Acids 2006; 31: 251-72.
    • (2006) Amino Acids , vol.31 , pp. 251-272
    • Ebner, K.1    Singewald, N.2
  • 102
    • 1642488331 scopus 로고    scopus 로고
    • Substance P in the medial amygdala: Emotional stress-sensitive release and modulation of anxiety-related behavior in rats
    • Ebner K, Rupniak NMJ, Saria A, Singewald N. Substance P in the medial amygdala: emotional stress-sensitive release and modulation of anxiety-related behavior in rats. Proc Natl Acad Sci USA 2004; 101: 4280-5.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 4280-4285
    • Ebner, K.1    Rupniak, N.M.J.2    Saria, A.3    Singewald, N.4
  • 103
    • 79251640951 scopus 로고    scopus 로고
    • A selective neurokinin-1 receptor antagonist in chronic PTSD: A randomized, double-blind, placebo-controlled, proof-of-concept trial
    • Mathew SJ, Vythilingam M, Murrough JW, et al. A selective neurokinin-1 receptor antagonist in chronic PTSD: A randomized, double-blind, placebo-controlled, proof-of-concept trial. Eur Neuropsychopharmacol 2011; 21: 221-9.
    • (2011) Eur Neuropsychopharmacol , vol.21 , pp. 221-229
    • Mathew, S.J.1    Vythilingam, M.2    Murrough, J.W.3
  • 104
    • 85047696280 scopus 로고    scopus 로고
    • Elevated cerebrospinal fluid substance P concentrations in posttraumatic stress disorder and major depression
    • Geracioti TD Jr., Carpenter LL, Owens MJ, et al. Elevated cerebrospinal fluid substance P concentrations in posttraumatic stress disorder and major depression. Am J Psychiatry 2006; 163: 637-43.
    • (2006) Am J Psychiatry , vol.163 , pp. 637-643
    • Geracioti Jr., T.D.1    Carpenter, L.L.2    Owens, M.J.3
  • 105
    • 80052493547 scopus 로고    scopus 로고
    • Corticotropinreleasing factor, interleukin-6, brain-derived neurotrophic factor, insulin-like growth factor-1, and substance P in the cerebrospinal fluid of civilians with posttraumatic stress disorder before and after treatment with paroxetine
    • Bonne O, Gill MG, Luckenbaugh DA, et al. Corticotropinreleasing factor, interleukin-6, brain-derived neurotrophic factor, insulin-like growth factor-1, and substance P in the cerebrospinal fluid of civilians with posttraumatic stress disorder before and after treatment with paroxetine. J Clin Psychiatry 2011; 72: 1124-8.
    • (2011) J Clin Psychiatry , vol.72 , pp. 1124-1128
    • Bonne, O.1    Gill, M.G.2    Luckenbaugh, D.A.3
  • 106
    • 67349222818 scopus 로고    scopus 로고
    • Decreased neurokinin-1 (substance P) receptor binding in patients with panic disorder: Positron emission tomographic study with [18F]SPA-RQ
    • Fujimura Y, Yasuno F, Farris A, et al. Decreased neurokinin-1 (substance P) receptor binding in patients with panic disorder: positron emission tomographic study with [18F]SPA-RQ. Biol Psychiatry 2009; 66:94-7.
    • (2009) Biol Psychiatry , vol.66 , pp. 94-97
    • Fujimura, Y.1    Yasuno, F.2    Farris, A.3
  • 107
    • 33947590288 scopus 로고    scopus 로고
    • Symptom provocation in specific phobia affects the substance P neurokinin-1 receptor system
    • Michelgard A, Appel L, Pissiota A, et al. Symptom provocation in specific phobia affects the substance P neurokinin-1 receptor system. Biol Psychiatry 2007; 61: 1002-6.
    • (2007) Biol Psychiatry , vol.61 , pp. 1002-1006
    • Michelgard, A.1    Appel, L.2    Pissiota, A.3
  • 108
    • 22444442937 scopus 로고    scopus 로고
    • Cerebral blood flow changes after treatment of social phobia with the neurokinin-1 antagonist GR205171, citalopram or placebo
    • Furmark T, Appel L, Michelgard A, et al. Cerebral blood flow changes after treatment of social phobia with the neurokinin-1 antagonist GR205171, citalopram or placebo. Biol Psychiatry 2005; 58: 132-42.
    • (2005) Biol Psychiatry , vol.58 , pp. 132-142
    • Furmark, T.1    Appel, L.2    Michelgard, A.3
  • 109
    • 32144442187 scopus 로고    scopus 로고
    • Lack of efficacy of the substance P (neurokinin1 receptor) antagonist aprepitant in the treatment of major depressive disorder
    • Keller M, Montgomery S, Ball W. Lack of efficacy of the substance P (neurokinin1 receptor) antagonist aprepitant in the treatment of major depressive disorder. Biol Psychiatry 2006; 59: 216-23.
    • (2006) Biol Psychiatry , vol.59 , pp. 216-223
    • Keller, M.1    Montgomery, S.2    Ball, W.3
  • 110
    • 84871388751 scopus 로고    scopus 로고
    • Glaxo Smith Kline [homepage on the internet], Accessed Jan 18
    • Glaxo Smith Kline [homepage on the internet]. Result Summary for 113211. http://www.gsk-clinicalstudyregister.com/result_detail.jsp?protocolId=113211&studyId=69BEE7E776F9-4595-8D33-AC49CFDABCF2&compound=orvepitant. Accessed Jan 18, 2012.
    • (2012) Result Summary For 113211
  • 111
    • 0025352832 scopus 로고
    • Core symptoms of posttraumatic stress disorder unimproved by alprazolam treatment
    • Braun P, Greenberg D, Dasberg H, Lerer B. Core symptoms of posttraumatic stress disorder unimproved by alprazolam treatment. J Clin Psychiatry 1990; 51: 236-8.
    • (1990) J Clin Psychiatry , vol.51 , pp. 236-238
    • Braun, P.1    Greenberg, D.2    Dasberg, H.3    Lerer, B.4
  • 112
    • 45849087618 scopus 로고    scopus 로고
    • Combination treatment with benzodiazepines and SSRIs for comorbid anxiety and depression
    • Dunlop BW, Davis PG. Combination treatment with benzodiazepines and SSRIs for comorbid anxiety and depression. Prim Care Companion J Clin Psychiatry 2008; 10: 222-8.
    • (2008) Prim Care Companion J Clin Psychiatry , vol.10 , pp. 222-228
    • Dunlop, B.W.1    Davis, P.G.2
  • 113
    • 62449310942 scopus 로고    scopus 로고
    • The modulation of GABA(A) receptors in the thalamus by eszopiclone and zolpidem
    • Jia F, Goldstein PA, Harrison NL. The modulation of GABA(A) receptors in the thalamus by eszopiclone and zolpidem. J Pharmacol Exp Ther 2009; 328:1000-6.
    • (2009) J Pharmacol Exp Ther , vol.328 , pp. 1000-1006
    • Jia, F.1    Goldstein, P.A.2    Harrison, N.L.3
  • 114
    • 8144226853 scopus 로고    scopus 로고
    • A receptors containing the alpha-5 subunit mediate the trace effect in aversive and appetitive conditioning and extinction of conditioned fear
    • A receptors containing the alpha-5 subunit mediate the trace effect in aversive and appetitive conditioning and extinction of conditioned fear. Eur J Neurosci 2004; 20: 1928-36.
    • (2004) Eur J Neurosci , vol.20 , pp. 1928-1936
    • Yee, B.K.1    Hauser, J.2    Dolgov, V.V.3
  • 115
    • 13944267958 scopus 로고    scopus 로고
    • Enhancing cannabinoid neurotransmission augments the extinction of conditioned fear
    • Chhatwal JP, Davis M, Maguschak KA, Ressler KJ. Enhancing cannabinoid neurotransmission augments the extinction of conditioned fear. Neuropsychopharmacology 2005; 30: 516-24.
    • (2005) Neuropsychopharmacology , vol.30 , pp. 516-524
    • Chhatwal, J.P.1    Davis, M.2    Maguschak, K.A.3    Ressler, K.J.4
  • 116
    • 33744825985 scopus 로고    scopus 로고
    • Effects of intra-amygdala infusion of CB1 receptor agonists on the reconsolidation of fear-potentiated startle
    • Lin HC, Mao SC, Gean PW. Effects of intra-amygdala infusion of CB1 receptor agonists on the reconsolidation of fear-potentiated startle. Learn Mem 2006; 13: 316-21.
    • (2006) Learn Mem , vol.13 , pp. 316-321
    • Lin, H.C.1    Mao, S.C.2    Gean, P.W.3
  • 117
    • 60349127390 scopus 로고    scopus 로고
    • The use of a synthetic cannabinoid in the management of treatment-resistant nightmares in posttraumatic stress disorder (PTSD)
    • Fraser, GA. The use of a synthetic cannabinoid in the management of treatment-resistant nightmares in posttraumatic stress disorder (PTSD). CNS Neurosci Ther 2009; 15: 84-8.
    • (2009) CNS Neurosci Ther , vol.15 , pp. 84-88
    • Fraser, G.A.1
  • 118
    • 84870058942 scopus 로고    scopus 로고
    • Omega-3 fatty acids for the treatment of depression: Systematic review and meta-analysis
    • epub ahead of print
    • Bloch MH, Hannestad J. Omega-3 fatty acids for the treatment of depression: systematic review and meta-analysis. Mol Psychiatry 2011; epub ahead of print.
    • (2011) Mol Psychiatry
    • Bloch, M.H.1    Hannestad, J.2
  • 119
    • 84870174809 scopus 로고
    • The therapeutic potential of LSD-25
    • Featherstone RM, Simon A, eds, Thomas: Sprinfield, IL
    • Cohen S. The therapeutic potential of LSD-25. In: Featherstone RM, Simon A, eds. A Pharmacologic Approach to the Study of the Mind. Thomas: Sprinfield, IL, 1959; pp. 251-8.
    • (1959) A Pharmacologic Approach to the Study of The Mind , pp. 251-258
    • Cohen, S.1
  • 120
    • 4644334535 scopus 로고    scopus 로고
    • Context and behavioral processes in extinction
    • Bouton ME. Context and behavioral processes in extinction. Learn Mem 2004; 11: 485-94.
    • (2004) Learn Mem , vol.11 , pp. 485-494
    • Bouton, M.E.1
  • 121
    • 36549089500 scopus 로고    scopus 로고
    • Neural mechanisms of extinction learning and retrieval
    • Quirk GJ, Mueller D. Neural mechanisms of extinction learning and retrieval. Neuropsychopharmacology 2008; 33: 56-72.
    • (2008) Neuropsychopharmacology , vol.33 , pp. 56-72
    • Quirk, G.J.1    Mueller, D.2
  • 122
    • 60749084639 scopus 로고    scopus 로고
    • Beyond extinction: Erasing human fear responses and preventing the return of fear
    • Kindt M, Soeter M, Vervliet B. Beyond extinction: erasing human fear responses and preventing the return of fear. Nat Neurosci 2009; 12: 256-8.
    • (2009) Nat Neurosci , vol.12 , pp. 256-258
    • Kindt, M.1    Soeter, M.2    Vervliet, B.3
  • 123
    • 33947402766 scopus 로고    scopus 로고
    • Molecular mechanisms of memory reconsolidation
    • Tronson NC, Taylor JR. Molecular mechanisms of memory reconsolidation. Nat Rev Neurosci 2007; 8: 262-75.
    • (2007) Nat Rev Neurosci , vol.8 , pp. 262-275
    • Tronson, N.C.1    Taylor, J.R.2
  • 124
    • 4644355629 scopus 로고    scopus 로고
    • Cognitive enhancers as adjuncts to psychotherapy: Use of D-cycloserine in phobic individuals to facilitate extinction of fear
    • Ressler KJ, Rothbaum BO, Tannenbaum L, et al. Cognitive enhancers as adjuncts to psychotherapy: use of D-cycloserine in phobic individuals to facilitate extinction of fear. Arch Gen Psychiatry 2004; 61: 1136-44.
    • (2004) Arch Gen Psychiatry , vol.61 , pp. 1136-1144
    • Ressler, K.J.1    Rothbaum, B.O.2    Tannenbaum, L.3
  • 125
    • 0030738310 scopus 로고    scopus 로고
    • Behavioral, sympathetic and adrenocortical responses to yohimbine in panic disorder patients and normal controls
    • Gurguis GN, Vitton BJ, Uhde TW. Behavioral, sympathetic and adrenocortical responses to yohimbine in panic disorder patients and normal controls. Psychiatry Res 1997; 16:27-39.
    • (1997) Psychiatry Res , vol.16 , pp. 27-39
    • Gurguis, G.N.1    Vitton, B.J.2    Uhde, T.W.3
  • 126
    • 0032811148 scopus 로고    scopus 로고
    • Yohimbine use in a natural setting: Effects on posttraumatic stress disorder
    • Southwick SM, Morgan CA, Charney DS, High JR. Yohimbine use in a natural setting: effects on posttraumatic stress disorder. Biol Psychiatry 1999; 46: 442-4.
    • (1999) Biol Psychiatry , vol.46 , pp. 442-444
    • Southwick, S.M.1    Morgan, C.A.2    Charney, D.S.3    High, J.R.4
  • 127
    • 1842579574 scopus 로고    scopus 로고
    • Adrenergic transmission facilitates extinction of conditioned fear in mice
    • Cain CK, Blouin AM, Barad M. Adrenergic transmission facilitates extinction of conditioned fear in mice. Learn Mem 2004; 11: 179-87.
    • (2004) Learn Mem , vol.11 , pp. 179-187
    • Cain, C.K.1    Blouin, A.M.2    Barad, M.3
  • 128
    • 72749089698 scopus 로고    scopus 로고
    • Pharmacological facilitation of fear extinction and the search for adjunct treatments for anxiety disorders the case of yohimbine
    • Holmes A, Quirk GJ. Pharmacological facilitation of fear extinction and the search for adjunct treatments for anxiety disorders the case of yohimbine. Trends Pharmacol Sci 2009; 131: 2-6.
    • (2009) Trends Pharmacol Sci , vol.131 , pp. 2-6
    • Holmes, A.1    Quirk, G.J.2
  • 129
    • 60749097365 scopus 로고    scopus 로고
    • Facilitation of fear extinction in phobic participants with a novel cognitive enhancer: A randomized placebo controlled trial of yohimbine augmentation
    • Powers MB, Smits JA, Otto MW, Sanders C, Emmelkamp PM. Facilitation of fear extinction in phobic participants with a novel cognitive enhancer: a randomized placebo controlled trial of yohimbine augmentation. J Anx Disord 2009; 23: 350-6.
    • (2009) J Anx Disord , vol.23 , pp. 350-356
    • Powers, M.B.1    Smits, J.A.2    Otto, M.W.3    Sanders, C.4    Emmelkamp, P.M.5
  • 130
    • 82655179828 scopus 로고    scopus 로고
    • Neurometabolic mechanisms for memory enhancement and neuroprotection of methylene blue
    • Rojas JC, Bruchey AK, Gonzalez-Lima F. Neurometabolic mechanisms for memory enhancement and neuroprotection of methylene blue. Prog Neurobiol 2012; 96: 32-45.
    • (2012) Prog Neurobiol , vol.96 , pp. 32-45
    • Rojas, J.C.1    Bruchey, A.K.2    Gonzalez-Lima, F.3
  • 131
    • 79851507774 scopus 로고    scopus 로고
    • Phenothiazine: The seven lives of pharmacology's first lead structure
    • Ohlow MJ, Moosmann B. Phenothiazine: the seven lives of pharmacology's first lead structure Drug Discov Today 2011; 16: 119-31.
    • (2011) Drug Discov Today , vol.16 , pp. 119-131
    • Ohlow, M.J.1    Moosmann, B.2
  • 132
    • 0030805455 scopus 로고    scopus 로고
    • Stimulation of respiration by methylene blue in rat liver mitochondria
    • Visarius TM, Stucki JW, Lauterburg BH. Stimulation of respiration by methylene blue in rat liver mitochondria. FEBS Lett 1997; 412: 157-60.
    • (1997) FEBS Lett , vol.412 , pp. 157-160
    • Visarius, T.M.1    Stucki, J.W.2    Lauterburg, B.H.3
  • 134
    • 4644359275 scopus 로고    scopus 로고
    • Extinction memory improvement by the metabolic enhancer methylene blue
    • Gonzalez-Lima F, Bruchey AK. Extinction memory improvement by the metabolic enhancer methylene blue. Learn Mem 2004; 11: 633-40.
    • (2004) Learn Mem , vol.11 , pp. 633-640
    • Gonzalez-Lima, F.1    Bruchey, A.K.2
  • 135
    • 33845964390 scopus 로고    scopus 로고
    • Methylene blue facilitates the extinction of fear in an animal model of susceptibility to learned helplessness
    • Wrubel KM, Barrett D, Shumake J, Johnson SE, Gonzalez-Lima F. Methylene blue facilitates the extinction of fear in an animal model of susceptibility to learned helplessness. Neurobiol Learn Mem 2007; 87: 209-17.
    • (2007) Neurobiol Learn Mem , vol.87 , pp. 209-217
    • Wrubel, K.M.1    Barrett, D.2    Shumake, J.3    Johnson, S.E.4    Gonzalez-Lima, F.5
  • 137
    • 0036530044 scopus 로고    scopus 로고
    • Role of adrenal stress hormones in forming lasting memories in the brain
    • McGaugh JL, Roozendaal B. Role of adrenal stress hormones in forming lasting memories in the brain. Curr Op Neurobiol 2002; 12: 205-10.
    • (2002) Curr Op Neurobiol , vol.12 , pp. 205-210
    • McGaugh, J.L.1    Roozendaal, B.2
  • 138
    • 33646146185 scopus 로고    scopus 로고
    • Systemic and intra-amygdala administration of glucocorticoid agonist and antagonist modulate extinction of conditioned fear
    • Yang YL, Chao PK, Lu KT. Systemic and intra-amygdala administration of glucocorticoid agonist and antagonist modulate extinction of conditioned fear. Neuropsychopharmacology 2006; 31:912-24.
    • (2006) Neuropsychopharmacology , vol.31 , pp. 912-924
    • Yang, Y.L.1    Chao, P.K.2    Lu, K.T.3
  • 139
    • 0032997435 scopus 로고    scopus 로고
    • Glucocoritcoid receptor activation in the rat nucleus of the solitary tract facilitates memory consolidation: Involvement of the basolateral amygdala
    • Roozendaal B, Williams CL, McGaugh JL. Glucocoritcoid receptor activation in the rat nucleus of the solitary tract facilitates memory consolidation: involvement of the basolateral amygdala. Eur J Neurosci 1999; 11: 1317-23.
    • (1999) Eur J Neurosci , vol.11 , pp. 1317-1323
    • Roozendaal, B.1    Williams, C.L.2    McGaugh, J.L.3
  • 140
    • 0037108954 scopus 로고    scopus 로고
    • Involvement of stress-released corticotropin-releasing hormone in the basolateral amygdala in regulating memory consolidation
    • Roozendaal B, Brunson KI, Holloway BI, McGaugh JL, Baram TZ. Involvement of stress-released corticotropin-releasing hormone in the basolateral amygdala in regulating memory consolidation. Proc Natl Acad Sci USA 2002; 99: 13908-13.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 13908-13913
    • Roozendaal, B.1    Brunson, K.I.2    Holloway, B.I.3    McGaugh, J.L.4    Baram, T.Z.5
  • 143
    • 74849097702 scopus 로고    scopus 로고
    • Enhancing exposure therapy for anxiety disorders with glucocorticoids: From basic mechanisms of emotional learning to clinical applications
    • Bentz D, Michael T, de Quervain D J-F, Wilhelm FH. Enhancing exposure therapy for anxiety disorders with glucocorticoids: From basic mechanisms of emotional learning to clinical applications. J Anxiety Disord 2010; 24: 223-30.
    • (2010) J Anxiety Disord , vol.24 , pp. 223-230
    • Bentz, D.1    Michael, T.2    de Quervain, D.J.-F.3    Wilhelm, F.H.4
  • 144
    • 39049108307 scopus 로고    scopus 로고
    • Effect of post-retrieval propranolol on psychophysiological responding during subsequent script-driven traumatic imagery in post-traumatic stress disorder
    • Brunet A, Orr SP, Tremblay J, Robertson K, Nader K, Pitman RK. Effect of post-retrieval propranolol on psychophysiological responding during subsequent script-driven traumatic imagery in post-traumatic stress disorder. J Psych Res 2008; 42: 503-6.
    • (2008) J Psych Res , vol.42 , pp. 503-506
    • Brunet, A.1    Orr, S.P.2    Tremblay, J.3    Robertson, K.4    Nader, K.5    Pitman, R.K.6
  • 145
    • 79960955704 scopus 로고    scopus 로고
    • Systemic mifepristone blocks reconsolidation of cue-conditioned fear; propranolol prevents this effect
    • Pitman RK, Milad MR, Igoe SA. Systemic mifepristone blocks reconsolidation of cue-conditioned fear; propranolol prevents this effect. Behav Neurosci 2011; 125:632-8.
    • (2011) Behav Neurosci , vol.125 , pp. 632-638
    • Pitman, R.K.1    Milad, M.R.2    Igoe, S.A.3
  • 146
    • 44649116437 scopus 로고    scopus 로고
    • Systemic inhibition of mammalian target of rapamycin inhibits fear memory reconsolidation
    • Blundell J, Kouser M, Powell CM. Systemic inhibition of mammalian target of rapamycin inhibits fear memory reconsolidation. Nuerobiol Learn Mem 2008; 90: 28-35.
    • (2008) Nuerobiol Learn Mem , vol.90 , pp. 28-35
    • Blundell, J.1    Kouser, M.2    Powell, C.M.3
  • 147
    • 0037039358 scopus 로고    scopus 로고
    • A rapamycin-sensitive signaling pathway contributes to longterm synaptic plasticity in the hippocampus
    • Tang SJ, Reis G, Kange H, Gingras AC, Sonenberg N, Schuman EM. A rapamycin-sensitive signaling pathway contributes to longterm synaptic plasticity in the hippocampus. Proc Natl Acad Sci USA 2002; 99: 467-72.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 467-472
    • Tang, S.J.1    Reis, G.2    Kange, H.3    Gingras, A.C.4    Sonenberg, N.5    Schuman, E.M.6
  • 148
    • 78649627177 scopus 로고    scopus 로고
    • Differing effects of systemically administered rapamycin on consolidation and reconsolidation of context vs. cued fear memories
    • Glover EM, Ressler KJ, Davis M. Differing effects of systemically administered rapamycin on consolidation and reconsolidation of context vs. cued fear memories. Learn Mem 2010; 17: 577-81.
    • (2010) Learn Mem , vol.17 , pp. 577-581
    • Glover, E.M.1    Ressler, K.J.2    Davis, M.3
  • 149
    • 33845606405 scopus 로고    scopus 로고
    • Translational control via the mammalian target of rapamycin pathway is critical for the formation and stability of long-term fear memory in amygdala neurons
    • Parsons RG, Gafford GM, Helmstetter FJ. Translational control via the mammalian target of rapamycin pathway is critical for the formation and stability of long-term fear memory in amygdala neurons. J Neurosci 2006; 26: 12977-83.
    • (2006) J Neurosci , vol.26 , pp. 12977-12983
    • Parsons, R.G.1    Gafford, G.M.2    Helmstetter, F.J.3
  • 150
    • 33847681841 scopus 로고    scopus 로고
    • The psychotherapeutic potential of MDMA (3,4- methylenedioxymethamphetamine): An evidence-based review
    • Parrott AC. The psychotherapeutic potential of MDMA (3,4- methylenedioxymethamphetamine): an evidence-based review. Psychopharmacology 2007; 191: 181-93.
    • (2007) Psychopharmacology , vol.191 , pp. 181-193
    • Parrott, A.C.1
  • 151
    • 0033738703 scopus 로고    scopus 로고
    • The serotonin uptake inhibitor citalopram reduces acute cardiovascular and vegetative effects of 3,4- methylenedioxymethamphetamine (Ecstasy) in healthy volunteers
    • Liechti ME, Vollenweider FX. The serotonin uptake inhibitor citalopram reduces acute cardiovascular and vegetative effects of 3,4- methylenedioxymethamphetamine (Ecstasy) in healthy volunteers. J Psychopharmacol 2000;14: 269-74.
    • (2000) J Psychopharmacol , vol.14 , pp. 269-274
    • Liechti, M.E.1    Vollenweider, F.X.2
  • 153
    • 65649098655 scopus 로고    scopus 로고
    • How could MDMA (ecstasy) help anxiety disorders? A neurobiological rationale
    • Johansen PO, Krebs TS. How could MDMA (ecstasy) help anxiety disorders? A neurobiological rationale. J Psychopharmacol 2009; 23:389-91.
    • (2009) J Psychopharmacol , vol.23 , pp. 389-391
    • Johansen, P.O.1    Krebs, T.S.2
  • 154
    • 78650582070 scopus 로고    scopus 로고
    • The safety and efficacy of ±3,4-methylenedioxymethamphetamineassisted psychotherapy in subjects with chronic, treatment-resistant posttraumatic stress disorder: The first randomomized controlled pilot study
    • Mithoefer MC, Wagner MT, Mithoefer AT, Jerome L, Doblin R. The safety and efficacy of ±3,4-methylenedioxymethamphetamineassisted psychotherapy in subjects with chronic, treatment-resistant posttraumatic stress disorder: the first randomomized controlled pilot study. J Psychopharmacol 2011; 25: 439-52.
    • (2011) J Psychopharmacol , vol.25 , pp. 439-452
    • Mithoefer, M.C.1    Wagner, M.T.2    Mithoefer, A.T.3    Jerome, L.4    Doblin, R.5
  • 155
    • 0041466261 scopus 로고    scopus 로고
    • The pharmacology and clinical pharmacology of 3,4-methylenedioxymethamphetamine (MDMA, "Ecstasy")
    • Green AR, Mechan AO, Elliott JM, O'Shea E, Colado MI. The pharmacology and clinical pharmacology of 3,4-methylenedioxymethamphetamine (MDMA, "Ecstasy"). Pharmacol Rev 2003; 55: 463-508.
    • (2003) Pharmacol Rev , vol.55 , pp. 463-508
    • Green, A.R.1    Mechan, A.O.2    Elliott, J.M.3    O'Shea, E.4    Colado, M.I.5
  • 157
    • 0029078456 scopus 로고
    • The monoamine oxidase-B inhibitor Ldeprenyl protects against 3,4-methylenedioxymethamphetamineinduced lipid peroxidation and long-term serotonergic deficits
    • Sprague TD, Nichols DE. The monoamine oxidase-B inhibitor Ldeprenyl protects against 3,4-methylenedioxymethamphetamineinduced lipid peroxidation and long-term serotonergic deficits. J Pharmaol Exp 1995; 273: 667-73.
    • (1995) J Pharmaol Exp , vol.273 , pp. 667-673
    • Sprague, T.D.1    Nichols, D.E.2
  • 158
    • 0032962796 scopus 로고    scopus 로고
    • Studies on the role of dopamine in the degeneration of 5-HT nerve endings in the brain of Dark Agouti rats following 3,4- methylenedioxymethamphetamine (MDMA or "ecstasy") administration
    • Colado MI, O'Shea E, Granados R, Esteban B, Martin AB, Green AR. Studies on the role of dopamine in the degeneration of 5-HT nerve endings in the brain of Dark Agouti rats following 3,4- methylenedioxymethamphetamine (MDMA or "ecstasy") administration. Br J Pharmacol 1999; 126: 911-24.
    • (1999) Br J Pharmacol , vol.126 , pp. 911-924
    • Colado, M.I.1    O'Shea, E.2    Granados, R.3    Esteban, B.4    Martin, A.B.5    Green, A.R.6
  • 159
    • 0030971740 scopus 로고    scopus 로고
    • Ecstasy (MDMA) in recreational users: Self-reported psychological and physiological effects
    • Davison D, Parrott AC, Ecstasy (MDMA) in recreational users: self-reported psychological and physiological effects. Human Psychopharmacol 1997; 12: 221-6.
    • (1997) Human Psychopharmacol , vol.12 , pp. 221-226
    • Davison, D.1    Parrott, A.C.2


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