Tumour necrosis factor alpha downregulates human hemojuvelin expression via a novel response element within its promoter

Journal of Biomedical Science

Volumn 19, Issue 1, 2012, Pages

  Salama, Mohamed Fouda ^a,b   Bayele, Henry K ^a   Srai, Surjit S K ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b Mansoura University   (Egypt)

Author keywords

Hemojuvelin; Inflammation; TNF

Indexed keywords

ALKALINE PHOSPHATASE; BONE MORPHOGENETIC PROTEIN 2; BONE MORPHOGENETIC PROTEIN 4; BONE MORPHOGENETIC PROTEIN 6; HEMOJUVELIN; HEPCIDIN; HEPCIDIN 1; INTERLEUKIN 6; IRON REGULATORY FACTOR; MESSENGER RNA; MYC PROTEIN; OSTEOCALCIN; SMAD1 PROTEIN; SMAD5 PROTEIN; SMAD8 PROTEIN; THROMBOMODULIN; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; ANTIMICROBIAL CATIONIC PEPTIDE; HFE2 PROTEIN, MOUSE; IRON; LIGAND; LIPOPOLYSACCHARIDE; MEMBRANE PROTEIN; SMAD PROTEIN;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DOWN REGULATION; FEMALE; GENE EXPRESSION; IN VIVO STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; SITE DIRECTED MUTAGENESIS; ANIMAL; CHEMICALLY INDUCED DISORDER; DNA RESPONSIVE ELEMENT; DRUG EFFECT; GENE EXPRESSION REGULATION; GENETICS; HEMOCHROMATOSIS; HUMAN; INFLAMMATION; METABOLISM; MOUSE MUTANT; PHOSPHORYLATION; TUMOR CELL LINE;

MUS;

ANIMALS; ANTIMICROBIAL CATIONIC PEPTIDES; CELL LINE, TUMOR; GENE EXPRESSION REGULATION; HEMOCHROMATOSIS; HUMANS; INFLAMMATION; INTERLEUKIN-6; IRON; LIGANDS; LIPOPOLYSACCHARIDES; MEMBRANE PROTEINS; MICE; MICE, KNOCKOUT; PHOSPHORYLATION; PROMOTER REGIONS, GENETIC; RESPONSE ELEMENTS; SMAD PROTEINS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84866514196     PISSN: 10217770     EISSN: 14230127     Source Type: Journal    
DOI: 10.1186/1423-0127-19-83     Document Type: Article

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