Gene knockdown by morpholino-modified oligonucleotides in the zebrafish (danio rerio) model: Applications for developmental toxicology

Methods in Molecular Biology

Volumn 889, Issue , 2012, Pages 51-71

  Timme Laragy, Alicia R ^a   Karchner, Sibel I ^a   Hahn, Mark E ^a  

^a WOODS HOLE OCEANOGRAPHIC INSTITUTION   (United States)

Author keywords

(5 10) Reverse genetics; Antisense; Aryl hydrocarbon receptor; Developmental toxicology; Knockdown; Mechanisms of toxicity; Morpholino; Oxidative stress

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE; 3,3',4,4',5 PENTACHLOROBIPHENYL; 3,4,5,3',4'-PENTACHLOROBIPHENYL; MORPHOLINO OLIGONUCLEOTIDE; POLYCHLORINATED BIPHENYL; TERATOGENIC AGENT; ZEBRAFISH PROTEIN;

ARTICLE; EMBRYO DEVELOPMENT; GENE SILENCING; IN VITRO STUDY; MICROINJECTION; MORPHOLOGY; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; SPAWNING; ZEBRA FISH; ANIMAL; CALIBRATION; CULTURE TECHNIQUE; DISEASE MODEL; GENETIC ENGINEERING; GENETICS; INSTRUMENTATION; METHODOLOGY; NEEDLE; PRENATAL DEVELOPMENT; REVERSE GENETICS; TOXICITY TESTING;

ANIMALS; CALIBRATION; CULTURE TECHNIQUES; DISEASE MODELS, ANIMAL; EMBRYONIC DEVELOPMENT; GENE KNOCKDOWN TECHNIQUES; GENETIC ENGINEERING; MICROINJECTIONS; MORPHOLINOS; NEEDLES; POLYCHLORINATED BIPHENYLS; REVERSE GENETICS; TERATOGENS; TOXICITY TESTS; ZEBRAFISH; ZEBRAFISH PROTEINS;

EID: 84866495351     PISSN: 10643745     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-61779-867-2_5     Document Type: Article

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