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Volumn 285, Issue 1, 2009, Pages 1-5

TRAIL as a target in anti-cancer therapy

Author keywords

Apoptosis; Chemosensitivity; Drug development; TRAIL

Indexed keywords

5 AZA 2' DEOXYCYTIDINE; BEVACIZUMAB; CARBOPLATIN; DEATH RECEPTOR 4; DEATH RECEPTOR 5; N (2 AMINOPHENYL) 4 (3 PYRIDINYLMETHOXYCARBONYLAMINOMETHYL)BENZAMIDE; PACLITAXEL; PROTEIN P53; RECOMBINANT TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND; RETINOIC ACID; RETINOID; RITUXIMAB; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND;

EID: 70149122276     PISSN: 03043835     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.canlet.2009.02.029     Document Type: Review
Times cited : (159)

References (68)
  • 1
    • 0037169358 scopus 로고    scopus 로고
    • Apoptosis: a link between cancer genetics and chemotherapy
    • Johnstone R.W., Ruefli A.A., and Lowe S.W. Apoptosis: a link between cancer genetics and chemotherapy. Cell 108 2 (2002) 153-164
    • (2002) Cell , vol.108 , Issue.2 , pp. 153-164
    • Johnstone, R.W.1    Ruefli, A.A.2    Lowe, S.W.3
  • 2
    • 0030892234 scopus 로고    scopus 로고
    • Apoptosis by death factor
    • Nagata S. Apoptosis by death factor. Cell 88 (1997) 355-365
    • (1997) Cell , vol.88 , pp. 355-365
    • Nagata, S.1
  • 3
    • 0032575714 scopus 로고    scopus 로고
    • Death receptors: signaling and modulation
    • Ashkenazi A., and Dixit V.M. Death receptors: signaling and modulation. Science 281 (1998) 1305-1308
    • (1998) Science , vol.281 , pp. 1305-1308
    • Ashkenazi, A.1    Dixit, V.M.2
  • 4
    • 25144489068 scopus 로고    scopus 로고
    • Overview of cell death signaling pathways
    • Jin Z., and El-Deiry W.S. Overview of cell death signaling pathways. Cancer Biol. Ther. 4 2 (2005) 139-163
    • (2005) Cancer Biol. Ther. , vol.4 , Issue.2 , pp. 139-163
    • Jin, Z.1    El-Deiry, W.S.2
  • 5
    • 0028883850 scopus 로고
    • Cytotoxicity-dependent APO-1 (Fas/CD95)-associated proteins form a death-inducing signaling complex (DISC) with the receptor
    • Kischkel F.C., Hellbardt S., Behrmann I., et al. Cytotoxicity-dependent APO-1 (Fas/CD95)-associated proteins form a death-inducing signaling complex (DISC) with the receptor. EMBO J. 14 (1995) 5579-5588
    • (1995) EMBO J. , vol.14 , pp. 5579-5588
    • Kischkel, F.C.1    Hellbardt, S.2    Behrmann, I.3
  • 6
    • 45749098451 scopus 로고    scopus 로고
    • To kill a tumor cell: the potential of proapoptotic receptor agonists
    • Ashkenazi A., and Herbst R.S. To kill a tumor cell: the potential of proapoptotic receptor agonists. J. Clin. Invest. 118 6 (2008) 1979-1990
    • (2008) J. Clin. Invest. , vol.118 , Issue.6 , pp. 1979-1990
    • Ashkenazi, A.1    Herbst, R.S.2
  • 7
    • 57049155399 scopus 로고    scopus 로고
    • Directing cancer cells to self-destruct with pro-apoptotic receptor agonists
    • Ashkenazi A. Directing cancer cells to self-destruct with pro-apoptotic receptor agonists. Nat. Rev. Drug Discov. 7 12 (2008) 1001-1012
    • (2008) Nat. Rev. Drug Discov. , vol.7 , Issue.12 , pp. 1001-1012
    • Ashkenazi, A.1
  • 8
    • 13344285339 scopus 로고
    • Identification and characterization of a new member of the TNF family that induces apoptosis
    • Wiley S.R., Schooley K., Smolak P.J., et al. Identification and characterization of a new member of the TNF family that induces apoptosis. Immunity 3 (1995) 673-682
    • (1995) Immunity , vol.3 , pp. 673-682
    • Wiley, S.R.1    Schooley, K.2    Smolak, P.J.3
  • 9
    • 17544367410 scopus 로고    scopus 로고
    • Induction of apoptosis by Apo-2 ligand, a new member of the tumor necrosis factor cytokine family
    • Pitti R.M., Marsters S.A., Ruppert S., Donahue C.J., Moore A., and Ashkenazi A. Induction of apoptosis by Apo-2 ligand, a new member of the tumor necrosis factor cytokine family. J. Biol. Chem. 271 (1996) 12687-12690
    • (1996) J. Biol. Chem. , vol.271 , pp. 12687-12690
    • Pitti, R.M.1    Marsters, S.A.2    Ruppert, S.3    Donahue, C.J.4    Moore, A.5    Ashkenazi, A.6
  • 10
    • 0032750511 scopus 로고    scopus 로고
    • Structure of the TRAIL-DR5 complex reveals mechanisms conferring specificity in apoptotic initiation
    • Mongkolsapaya J., Grimes J.M., Chen N., et al. Structure of the TRAIL-DR5 complex reveals mechanisms conferring specificity in apoptotic initiation. Nat. Struct. Biol. 6 11 (1999) 1048-1053
    • (1999) Nat. Struct. Biol. , vol.6 , Issue.11 , pp. 1048-1053
    • Mongkolsapaya, J.1    Grimes, J.M.2    Chen, N.3
  • 11
    • 0030996297 scopus 로고    scopus 로고
    • The receptor for the cytotoxic ligand TRAIL
    • Pan G., O'Rourke K., Chinnaiyan A.M., et al. The receptor for the cytotoxic ligand TRAIL. Science 276 (1997) 111-113
    • (1997) Science , vol.276 , pp. 111-113
    • Pan, G.1    O'Rourke, K.2    Chinnaiyan, A.M.3
  • 12
    • 0031253977 scopus 로고    scopus 로고
    • KILLER/DR5 is a DNA damage-inducible p53-regulated death receptor gene
    • Wu G.S., Burns T.F., McDonald E.R., et al. KILLER/DR5 is a DNA damage-inducible p53-regulated death receptor gene. Nat. Genet. 17 (1997) 141-143
    • (1997) Nat. Genet. , vol.17 , pp. 141-143
    • Wu, G.S.1    Burns, T.F.2    McDonald, E.R.3
  • 14
    • 0030762815 scopus 로고    scopus 로고
    • An antagonist decoy receptor and a death domain-containing receptor for TRAIL
    • Pan G., Ni J., Wei Y.F., Yu G., Gentz R., and Dixit V.M. An antagonist decoy receptor and a death domain-containing receptor for TRAIL. Science 277 (1997) 815-818
    • (1997) Science , vol.277 , pp. 815-818
    • Pan, G.1    Ni, J.2    Wei, Y.F.3    Yu, G.4    Gentz, R.5    Dixit, V.M.6
  • 15
    • 0030880548 scopus 로고    scopus 로고
    • TRAIL-R2: a novel apoptosis-mediating receptor for TRAIL
    • Walczak H., Degli-Esposti M.A., Johnson R.S., et al. TRAIL-R2: a novel apoptosis-mediating receptor for TRAIL. EMBO J. 16 (1997) 5386-5397
    • (1997) EMBO J. , vol.16 , pp. 5386-5397
    • Walczak, H.1    Degli-Esposti, M.A.2    Johnson, R.S.3
  • 16
  • 17
    • 0030869432 scopus 로고    scopus 로고
    • Cloning and characterization of TRAIL-R3, a novel member of the emerging TRAIL receptor family
    • Degli-Esposti M.A., Smolak P.J., Walczak H., et al. Cloning and characterization of TRAIL-R3, a novel member of the emerging TRAIL receptor family. J. Exp. Med. 186 (1997) 1165-1170
    • (1997) J. Exp. Med. , vol.186 , pp. 1165-1170
    • Degli-Esposti, M.A.1    Smolak, P.J.2    Walczak, H.3
  • 18
    • 0030792712 scopus 로고    scopus 로고
    • Control of TRAIL-induced apoptosis by a family of signaling and decoy receptors
    • Sheridan J.P., Marsters S.A., Pitti R.M., et al. Control of TRAIL-induced apoptosis by a family of signaling and decoy receptors. Science 277 (1997) 818-821
    • (1997) Science , vol.277 , pp. 818-821
    • Sheridan, J.P.1    Marsters, S.A.2    Pitti, R.M.3
  • 19
    • 0031627483 scopus 로고    scopus 로고
    • Lymphocyte inhibitor of TRAIL (TNF-related apoptosis-inducing ligand): a new receptor protecting lymphocytes from the death ligand TRAIL
    • Mongkolsapaya J., Cowper A.E., Xu X.N., et al. Lymphocyte inhibitor of TRAIL (TNF-related apoptosis-inducing ligand): a new receptor protecting lymphocytes from the death ligand TRAIL. J. Immunol. 160 (1998) 3-6
    • (1998) J. Immunol. , vol.160 , pp. 3-6
    • Mongkolsapaya, J.1    Cowper, A.E.2    Xu, X.N.3
  • 20
    • 0032489353 scopus 로고    scopus 로고
    • TRUNDD, a new member of the TRAIL receptor family that antagonizes TRAIL signalling
    • Pan G., Ni J., Yu G., Wei Y.F., and Dixit V.M. TRUNDD, a new member of the TRAIL receptor family that antagonizes TRAIL signalling. FEBS Lett. 424 (1998) 41-45
    • (1998) FEBS Lett. , vol.424 , pp. 41-45
    • Pan, G.1    Ni, J.2    Yu, G.3    Wei, Y.F.4    Dixit, V.M.5
  • 21
    • 13144265771 scopus 로고    scopus 로고
    • A novel receptor for Apo2L/TRAIL contains a truncated death domain
    • Marsters S.A., Sheridan J.P., Pitti R.M., et al. A novel receptor for Apo2L/TRAIL contains a truncated death domain. Curr. Biol. 7 (1997) 1003-1006
    • (1997) Curr. Biol. , vol.7 , pp. 1003-1006
    • Marsters, S.A.1    Sheridan, J.P.2    Pitti, R.M.3
  • 22
    • 0031414749 scopus 로고    scopus 로고
    • The novel receptor TRAIL-R4 induces NF-kappaB and protects against TRAIL-mediated apoptosis, yet retains an incomplete death domain
    • Degli-Esposti M.A., Dougall W.C., Smolak P.J., Waugh J.Y., Smith C.A., and Goodwin R.G. The novel receptor TRAIL-R4 induces NF-kappaB and protects against TRAIL-mediated apoptosis, yet retains an incomplete death domain. Immunity 7 (1997) 813-820
    • (1997) Immunity , vol.7 , pp. 813-820
    • Degli-Esposti, M.A.1    Dougall, W.C.2    Smolak, P.J.3    Waugh, J.Y.4    Smith, C.A.5    Goodwin, R.G.6
  • 23
    • 7344233085 scopus 로고    scopus 로고
    • Osteoprotegerin is a receptor for the cytotoxic ligand TRAIL
    • Emery J.G., McDonnell P., Burke M.B., et al. Osteoprotegerin is a receptor for the cytotoxic ligand TRAIL. J. Biol. Chem. 273 (1998) 14363-14367
    • (1998) J. Biol. Chem. , vol.273 , pp. 14363-14367
    • Emery, J.G.1    McDonnell, P.2    Burke, M.B.3
  • 24
    • 0001203366 scopus 로고    scopus 로고
    • Molecular cloning and functional analysis of the mouse homologue of the KILLER/DR5 tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) death receptor
    • Wu G.S., Burns T.F., Zhan Y., Alnemri E.S., and El-Deiry W.S. Molecular cloning and functional analysis of the mouse homologue of the KILLER/DR5 tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) death receptor. Cancer Res. 59 (1999) 2770-2775
    • (1999) Cancer Res. , vol.59 , pp. 2770-2775
    • Wu, G.S.1    Burns, T.F.2    Zhan, Y.3    Alnemri, E.S.4    El-Deiry, W.S.5
  • 25
    • 0038320035 scopus 로고    scopus 로고
    • Apo2L/TRAIL: apoptosis signaling, biology, and potential for cancer therapy
    • Almasan A., and Ashkenazi A. Apo2L/TRAIL: apoptosis signaling, biology, and potential for cancer therapy. Cytokine Growth Factor Rev. 14 3-4 (2003) 337-348
    • (2003) Cytokine Growth Factor Rev. , vol.14 , Issue.3-4 , pp. 337-348
    • Almasan, A.1    Ashkenazi, A.2
  • 26
    • 3543035176 scopus 로고    scopus 로고
    • Rare loss-of-function mutation of a death receptor gene in head and neck cancer
    • Pai S., Wu G.S., Ozoren N., Wu L., Jen J., Sidransky D., and El-Deiry W.S. Rare loss-of-function mutation of a death receptor gene in head and neck cancer. Cancer Res. 58 16 (1998) 3513-3518
    • (1998) Cancer Res. , vol.58 , Issue.16 , pp. 3513-3518
    • Pai, S.1    Wu, G.S.2    Ozoren, N.3    Wu, L.4    Jen, J.5    Sidransky, D.6    El-Deiry, W.S.7
  • 27
    • 0037621450 scopus 로고    scopus 로고
    • Silencing of death receptor and caspase-8 expression in small cell lung carcinoma cell lines and tumors by DNA methylation
    • Hopkins-Donaldson S., Ziegler A., Kurtz S., et al. Silencing of death receptor and caspase-8 expression in small cell lung carcinoma cell lines and tumors by DNA methylation. Cell Death Differ. 10 3 (2003) 356-364
    • (2003) Cell Death Differ. , vol.10 , Issue.3 , pp. 356-364
    • Hopkins-Donaldson, S.1    Ziegler, A.2    Kurtz, S.3
  • 28
    • 0035851189 scopus 로고    scopus 로고
    • Identification of inhibitors of TRAIL-induced death (ITIDs) in the TRAIL-sensitive colon carcinoma cell line SW480 using a genetic approach
    • Burns T.F., and El-Deiry W.S. Identification of inhibitors of TRAIL-induced death (ITIDs) in the TRAIL-sensitive colon carcinoma cell line SW480 using a genetic approach. J. Biol. Chem. 276 41 (2001) 37879-37886
    • (2001) J. Biol. Chem. , vol.276 , Issue.41 , pp. 37879-37886
    • Burns, T.F.1    El-Deiry, W.S.2
  • 29
    • 0037151079 scopus 로고    scopus 로고
    • An inducible pathway for degradation of FLIP protein sensitizes tumor cells to TRAIL-induced apoptosis
    • Kim Y., Suh N., Sporn M., and Reed J.C. An inducible pathway for degradation of FLIP protein sensitizes tumor cells to TRAIL-induced apoptosis. J. Biol. Chem. 277 25 (2002) 22320-22329
    • (2002) J. Biol. Chem. , vol.277 , Issue.25 , pp. 22320-22329
    • Kim, Y.1    Suh, N.2    Sporn, M.3    Reed, J.C.4
  • 30
    • 0037312929 scopus 로고    scopus 로고
    • Erythroid differentiation sensitizes K562 leukemia cells to TRAIL-induced apoptosis by downregulation of c-FLIP
    • Hietakangas V., Poukkula M., Heiskanen K.M., Karvinen J.T., Sistonen L., and Eriksson J.E. Erythroid differentiation sensitizes K562 leukemia cells to TRAIL-induced apoptosis by downregulation of c-FLIP. Mol. Cell Biol. 23 4 (2003) 1278-1291
    • (2003) Mol. Cell Biol. , vol.23 , Issue.4 , pp. 1278-1291
    • Hietakangas, V.1    Poukkula, M.2    Heiskanen, K.M.3    Karvinen, J.T.4    Sistonen, L.5    Eriksson, J.E.6
  • 31
    • 0034805181 scopus 로고    scopus 로고
    • Overexpression of bcl2 blocks TNF-related apoptosis-inducing ligand (TRAIL)-induced apoptosis in human lung cancer cells
    • Sun S.Y., Yue P., Zhou J.-Y., et al. Overexpression of bcl2 blocks TNF-related apoptosis-inducing ligand (TRAIL)-induced apoptosis in human lung cancer cells. BBRC 280 (2001) 788-797
    • (2001) BBRC , vol.280 , pp. 788-797
    • Sun, S.Y.1    Yue, P.2    Zhou, J.-Y.3
  • 32
    • 0036141029 scopus 로고    scopus 로고
    • TRAIL-induced apoptosis requires Bax-dependent mitochondrial release of Smac/DIABLO
    • Deng Y., Lin Y., and Wu X. TRAIL-induced apoptosis requires Bax-dependent mitochondrial release of Smac/DIABLO. Genes Dev. 16 1 (2002) 33-45
    • (2002) Genes Dev. , vol.16 , Issue.1 , pp. 33-45
    • Deng, Y.1    Lin, Y.2    Wu, X.3
  • 33
    • 2342615480 scopus 로고    scopus 로고
    • X-linked inhibitor of apoptosis protein (XIAP) is a nonredundant modulator of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-mediated apoptosis in human cancer cells
    • Cummins J.M., Kohli M., Rago C., Kinzler K.W., Vogelstein B., and Bunz F. X-linked inhibitor of apoptosis protein (XIAP) is a nonredundant modulator of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-mediated apoptosis in human cancer cells. Cancer Res. 64 9 (2004) 3006-3008
    • (2004) Cancer Res. , vol.64 , Issue.9 , pp. 3006-3008
    • Cummins, J.M.1    Kohli, M.2    Rago, C.3    Kinzler, K.W.4    Vogelstein, B.5    Bunz, F.6
  • 34
    • 4344660599 scopus 로고    scopus 로고
    • Downregulation of Bcl-2, FLIP or IAPs (XIAP and survivin) by siRNAs sensitizes resistant melanoma cells to Apo2L/TRAIL-induced apoptosis
    • Chawla-Sarkar M., Bae S.I., Reu F.J., Jacobs B.S., Lindner D.J., and Borden E.C. Downregulation of Bcl-2, FLIP or IAPs (XIAP and survivin) by siRNAs sensitizes resistant melanoma cells to Apo2L/TRAIL-induced apoptosis. Cell Death Differ. 11 8 (2004) 915-923
    • (2004) Cell Death Differ. , vol.11 , Issue.8 , pp. 915-923
    • Chawla-Sarkar, M.1    Bae, S.I.2    Reu, F.J.3    Jacobs, B.S.4    Lindner, D.J.5    Borden, E.C.6
  • 35
    • 17944379442 scopus 로고    scopus 로고
    • CD95 and TRAIL receptor-mediated activation of protein kinase C and NF-kappaB contributes to apoptosis resistance in ductal pancreatic adenocarcinoma cells
    • Trauzold A., Wermann H., Arlt A., et al. CD95 and TRAIL receptor-mediated activation of protein kinase C and NF-kappaB contributes to apoptosis resistance in ductal pancreatic adenocarcinoma cells. Oncogene 20 31 (2001) 4258-4269
    • (2001) Oncogene , vol.20 , Issue.31 , pp. 4258-4269
    • Trauzold, A.1    Wermann, H.2    Arlt, A.3
  • 36
    • 0038339094 scopus 로고    scopus 로고
    • TRAIL induced survival and proliferation in cancer cells resistant towards TRAIL-induced apoptosis mediated by NF-kappaB
    • Ehrhardt H., Fulda S., Schmid I., Hiscott J., Debatin K.M., and Jeremias I. TRAIL induced survival and proliferation in cancer cells resistant towards TRAIL-induced apoptosis mediated by NF-kappaB. Oncogene 22 25 (2003) 3842-3852
    • (2003) Oncogene , vol.22 , Issue.25 , pp. 3842-3852
    • Ehrhardt, H.1    Fulda, S.2    Schmid, I.3    Hiscott, J.4    Debatin, K.M.5    Jeremias, I.6
  • 37
    • 24744462114 scopus 로고    scopus 로고
    • Tumor necrosis factor-related apoptosis-inducing ligand-mediated proliferation of tumor cells with receptor-proximal apoptosis defects
    • Baader E., Toloczko A., Fuchs U., et al. Tumor necrosis factor-related apoptosis-inducing ligand-mediated proliferation of tumor cells with receptor-proximal apoptosis defects. Cancer Res. 65 17 (2005) 7888-7895
    • (2005) Cancer Res. , vol.65 , Issue.17 , pp. 7888-7895
    • Baader, E.1    Toloczko, A.2    Fuchs, U.3
  • 38
    • 0038414629 scopus 로고    scopus 로고
    • TRAIL promotes the survival and proliferation of primary human vascular endothelial cells by activating the Akt and ERK pathways
    • Secchiero P., Gonelli A., Carnevale E., et al. TRAIL promotes the survival and proliferation of primary human vascular endothelial cells by activating the Akt and ERK pathways. Circulation 107 17 (2003) 2250-2256
    • (2003) Circulation , vol.107 , Issue.17 , pp. 2250-2256
    • Secchiero, P.1    Gonelli, A.2    Carnevale, E.3
  • 39
    • 4143082567 scopus 로고    scopus 로고
    • TRAIL promotes the survival, migration and proliferation of vascular smooth muscle cells
    • Secchiero P., Zerbinati C., Rimondi E., et al. TRAIL promotes the survival, migration and proliferation of vascular smooth muscle cells. Cell Mol. Life. Sci. 61 15 (2004) 1965-1974
    • (2004) Cell Mol. Life. Sci. , vol.61 , Issue.15 , pp. 1965-1974
    • Secchiero, P.1    Zerbinati, C.2    Rimondi, E.3
  • 40
    • 33845221022 scopus 로고    scopus 로고
    • TRAIL promotes metastasis of human pancreatic ductal adenocarcinoma
    • Trauzold A., Siegmund D., Schniewind B., et al. TRAIL promotes metastasis of human pancreatic ductal adenocarcinoma. Oncogene 25 56 (2006) 7434-7439
    • (2006) Oncogene , vol.25 , Issue.56 , pp. 7434-7439
    • Trauzold, A.1    Siegmund, D.2    Schniewind, B.3
  • 41
    • 34347246278 scopus 로고    scopus 로고
    • Reduction of TRAIL-induced Mcl-1 and cIAP2 by c-Myc or sorafenib sensitizes resistant human cancer cells to TRAIL-induced death
    • Ricci M.S., Kim S.H., Ogi K., et al. Reduction of TRAIL-induced Mcl-1 and cIAP2 by c-Myc or sorafenib sensitizes resistant human cancer cells to TRAIL-induced death. Cancer cell 12 1 (2007) 66-80
    • (2007) Cancer cell , vol.12 , Issue.1 , pp. 66-80
    • Ricci, M.S.1    Kim, S.H.2    Ogi, K.3
  • 42
    • 0033547306 scopus 로고    scopus 로고
    • Induction of the TRAIL receptor KILLER/DR5 in p53-dependent apoptosis but not growth
    • Wu G.S., Burns T.F., McDonald E.R., et al. Induction of the TRAIL receptor KILLER/DR5 in p53-dependent apoptosis but not growth. Oncogene 18 (1999) 6411-6418
    • (1999) Oncogene , vol.18 , pp. 6411-6418
    • Wu, G.S.1    Burns, T.F.2    McDonald, E.R.3
  • 43
    • 0032522463 scopus 로고    scopus 로고
    • P53-dependent and -independent regulation of the death receptor KILLER/DR5 gene expression in response to genotoxic stress and tumor necrosis factor alpha
    • Sheikh M.S., Burns T.F., Huang Y., et al. P53-dependent and -independent regulation of the death receptor KILLER/DR5 gene expression in response to genotoxic stress and tumor necrosis factor alpha. Cancer Res. 58 8 (1998) 1593-1598
    • (1998) Cancer Res. , vol.58 , Issue.8 , pp. 1593-1598
    • Sheikh, M.S.1    Burns, T.F.2    Huang, Y.3
  • 44
    • 0037046509 scopus 로고    scopus 로고
    • Evidence that the human death receptor 4 is regulated by activator protein 1
    • Guan B., Yue P., Lotan R., and Sun S.Y. Evidence that the human death receptor 4 is regulated by activator protein 1. Oncogene 21 20 (2002) 3121-3129
    • (2002) Oncogene , vol.21 , Issue.20 , pp. 3121-3129
    • Guan, B.1    Yue, P.2    Lotan, R.3    Sun, S.Y.4
  • 45
    • 0035008833 scopus 로고    scopus 로고
    • Evidence that the death receptor DR4 is a DNA damage-inducible, p53-regulated gene
    • Guan B., Yue P., Clayman G.L., and Sun S.Y. Evidence that the death receptor DR4 is a DNA damage-inducible, p53-regulated gene. J. Cell. Physiol. 188 1 (2001) 98-105
    • (2001) J. Cell. Physiol. , vol.188 , Issue.1 , pp. 98-105
    • Guan, B.1    Yue, P.2    Clayman, G.L.3    Sun, S.Y.4
  • 46
    • 0034736062 scopus 로고    scopus 로고
    • Genomic organization and transcriptional regulation of human Apo2/TRAIL gene
    • Gong B., and Almasan A. Genomic organization and transcriptional regulation of human Apo2/TRAIL gene. Biochem. Bioph. Res. Commun. 278 3 (2000) 747-752
    • (2000) Biochem. Bioph. Res. Commun. , vol.278 , Issue.3 , pp. 747-752
    • Gong, B.1    Almasan, A.2
  • 47
    • 0034710821 scopus 로고    scopus 로고
    • Isolation and molecular characterization of the 5′-upstream region of the human TRAIL gene
    • Wang Q., Ji Y., Wang X., and Evers B.M. Isolation and molecular characterization of the 5′-upstream region of the human TRAIL gene. Biochem. Biophys. Res. Commun. 276 2 (2000) 466-471
    • (2000) Biochem. Biophys. Res. Commun. , vol.276 , Issue.2 , pp. 466-471
    • Wang, Q.1    Ji, Y.2    Wang, X.3    Evers, B.M.4
  • 48
    • 4143116932 scopus 로고    scopus 로고
    • Tumor suppressor IRF-1 mediates retinoid and interferon anticancer signaling to death ligand TRAIL
    • Clarke N., Jimenez-Lara A.M., Voltz E., and Gronemeyer H. Tumor suppressor IRF-1 mediates retinoid and interferon anticancer signaling to death ligand TRAIL. Embo J. 23 15 (2004) 3051-3060
    • (2004) Embo J. , vol.23 , Issue.15 , pp. 3051-3060
    • Clarke, N.1    Jimenez-Lara, A.M.2    Voltz, E.3    Gronemeyer, H.4
  • 49
    • 21644466490 scopus 로고    scopus 로고
    • Identification of TRAIL as an interferon regulatory factor 3 transcriptional target
    • Kirshner J.R., Karpova A.Y., Kops M., and Howley P.M. Identification of TRAIL as an interferon regulatory factor 3 transcriptional target. J. Virol. 79 14 (2005) 9320-9324
    • (2005) J. Virol. , vol.79 , Issue.14 , pp. 9320-9324
    • Kirshner, J.R.1    Karpova, A.Y.2    Kops, M.3    Howley, P.M.4
  • 50
    • 0035798624 scopus 로고    scopus 로고
    • NF-kappaB signaling pathway governs TRAIL gene expression and human T-cell leukemia virus-I Tax-induced T-cell death
    • Rivera-Walsh I., Waterfield M., Xiao G., Fong A., and Sun S.C. NF-kappaB signaling pathway governs TRAIL gene expression and human T-cell leukemia virus-I Tax-induced T-cell death. J. Biol. Chem. 276 44 (2001) 40385-40388
    • (2001) J. Biol. Chem. , vol.276 , Issue.44 , pp. 40385-40388
    • Rivera-Walsh, I.1    Waterfield, M.2    Xiao, G.3    Fong, A.4    Sun, S.C.5
  • 51
    • 0035883162 scopus 로고    scopus 로고
    • Disruption of NF-kappaB signaling reveals a novel role for NF-kappaB in the regulation of TNF-related apoptosis-inducing ligand expression
    • Baetu T.M., Kwon H., Sharma S., Grandvaux N., and Hiscott J. Disruption of NF-kappaB signaling reveals a novel role for NF-kappaB in the regulation of TNF-related apoptosis-inducing ligand expression. J. Immunol. 167 6 (2001) 3164-3173
    • (2001) J. Immunol. , vol.167 , Issue.6 , pp. 3164-3173
    • Baetu, T.M.1    Kwon, H.2    Sharma, S.3    Grandvaux, N.4    Hiscott, J.5
  • 52
    • 0034961181 scopus 로고    scopus 로고
    • Retinoic acid-induced apoptosis in leukemia cells is mediated by paracrine action of tumor-selective death ligand TRAIL
    • Altucci L., Rossin A., Raffelsberger W., Reitmair A., Chomienne C., and Gronemeyer H. Retinoic acid-induced apoptosis in leukemia cells is mediated by paracrine action of tumor-selective death ligand TRAIL. Nat. Med. 7 6 (2001) 680-686
    • (2001) Nat. Med. , vol.7 , Issue.6 , pp. 680-686
    • Altucci, L.1    Rossin, A.2    Raffelsberger, W.3    Reitmair, A.4    Chomienne, C.5    Gronemeyer, H.6
  • 53
    • 13444306459 scopus 로고    scopus 로고
    • Tumor-selective action of HDAC inhibitors involves TRAIL induction in acute myeloid leukemia cells
    • Nebbioso A., Clarke N., Voltz E., et al. Tumor-selective action of HDAC inhibitors involves TRAIL induction in acute myeloid leukemia cells. Nat. Med. 11 (2005) 77-84
    • (2005) Nat. Med. , vol.11 , pp. 77-84
    • Nebbioso, A.1    Clarke, N.2    Voltz, E.3
  • 54
    • 13444274622 scopus 로고    scopus 로고
    • Inhibitors of histone deacetylases induce tumor-selective apoptosis through activation of the death receptor pathway
    • Insinga A., Monestiroli S., Ronzoni S., et al. Inhibitors of histone deacetylases induce tumor-selective apoptosis through activation of the death receptor pathway. Nat. Med. 11 (2005) 71-76
    • (2005) Nat. Med. , vol.11 , pp. 71-76
    • Insinga, A.1    Monestiroli, S.2    Ronzoni, S.3
  • 55
    • 33750535200 scopus 로고    scopus 로고
    • Tumor necrosis factor-related apoptosis-inducing ligand is required for tumor necrosis factor {alpha}-mediated sensitization of human breast cancer cells to chemotherapy
    • Xu J., Zhou J.Y., and Wu G.S. Tumor necrosis factor-related apoptosis-inducing ligand is required for tumor necrosis factor {alpha}-mediated sensitization of human breast cancer cells to chemotherapy. Cancer Res. 66 20 (2006) 10092-10099
    • (2006) Cancer Res. , vol.66 , Issue.20 , pp. 10092-10099
    • Xu, J.1    Zhou, J.Y.2    Wu, G.S.3
  • 56
    • 33847042352 scopus 로고    scopus 로고
    • Evidence that tumor necrosis factor-related apoptosis-inducing ligand induction by 5-aza-2′-deoxycytidine sensitizes human breast cancer cells to adriamycin
    • Xu J., Zhou J.Y., Tainsky M.A., and Wu G.S. Evidence that tumor necrosis factor-related apoptosis-inducing ligand induction by 5-aza-2′-deoxycytidine sensitizes human breast cancer cells to adriamycin. Cancer Res. 67 3 (2007) 1203-1211
    • (2007) Cancer Res. , vol.67 , Issue.3 , pp. 1203-1211
    • Xu, J.1    Zhou, J.Y.2    Tainsky, M.A.3    Wu, G.S.4
  • 57
    • 53049107304 scopus 로고    scopus 로고
    • Sp1-mediated TRAIL induction in chemosensitization
    • Xu J., Zhou J.Y., Wei W.Z., Philipsen S., and Wu G.S. Sp1-mediated TRAIL induction in chemosensitization. Cancer Res. 68 16 (2008) 6718-6726
    • (2008) Cancer Res. , vol.68 , Issue.16 , pp. 6718-6726
    • Xu, J.1    Zhou, J.Y.2    Wei, W.Z.3    Philipsen, S.4    Wu, G.S.5
  • 58
    • 58149116500 scopus 로고    scopus 로고
    • TNFSF10 (TRAIL), a p53 target gene that mediates p53-dependent cell death
    • Kuribayashi K., Krigsfeld G., Wang W., et al. TNFSF10 (TRAIL), a p53 target gene that mediates p53-dependent cell death. Cancer Biol. Ther. 7 12 (2008)
    • (2008) Cancer Biol. Ther. , vol.7 , Issue.12
    • Kuribayashi, K.1    Krigsfeld, G.2    Wang, W.3
  • 59
    • 0032929520 scopus 로고    scopus 로고
    • Tumoricidal activity of tumor necrosis factor-related apoptosis-inducing ligand in vivo
    • Walczak H., Miller R.E., Ariail K., et al. Tumoricidal activity of tumor necrosis factor-related apoptosis-inducing ligand in vivo. Nat. Med. 5 2 (1999) 157-163
    • (1999) Nat. Med. , vol.5 , Issue.2 , pp. 157-163
    • Walczak, H.1    Miller, R.E.2    Ariail, K.3
  • 60
    • 49049086338 scopus 로고    scopus 로고
    • Ligand-based targeting of apoptosis in cancer: the potential of recombinant human apoptosis ligand 2/Tumor necrosis factor-related apoptosis-inducing ligand (rhApo2L/TRAIL)
    • Ashkenazi A., Holland P., and Eckhardt S.G. Ligand-based targeting of apoptosis in cancer: the potential of recombinant human apoptosis ligand 2/Tumor necrosis factor-related apoptosis-inducing ligand (rhApo2L/TRAIL). J. Clin. Oncol. 26 21 (2008) 3621-3630
    • (2008) J. Clin. Oncol. , vol.26 , Issue.21 , pp. 3621-3630
    • Ashkenazi, A.1    Holland, P.2    Eckhardt, S.G.3
  • 61
    • 0034022160 scopus 로고    scopus 로고
    • Apoptosis induced in normal human hepatocytes by tumor necrosis factor-related apoptosis-inducing ligand
    • Jo M., Kim T.H., Seol D.W., et al. Apoptosis induced in normal human hepatocytes by tumor necrosis factor-related apoptosis-inducing ligand. Nat. Med. 6 5 (2000) 564-567
    • (2000) Nat. Med. , vol.6 , Issue.5 , pp. 564-567
    • Jo, M.1    Kim, T.H.2    Seol, D.W.3
  • 62
    • 0035050960 scopus 로고    scopus 로고
    • Differential hepatocyte toxicity of recombinant Apo2L/TRAIL versions
    • Lawrence D., Shahrokh Z., Marsters S., et al. Differential hepatocyte toxicity of recombinant Apo2L/TRAIL versions. Nat. Med. 7 4 (2001) 383-385
    • (2001) Nat. Med. , vol.7 , Issue.4 , pp. 383-385
    • Lawrence, D.1    Shahrokh, Z.2    Marsters, S.3
  • 63
    • 9244237679 scopus 로고    scopus 로고
    • TRAIL inhibits tumor growth but is nontoxic to human hepatocytes in chimeric mice
    • Hao C., Song J.H., Hsi B., et al. TRAIL inhibits tumor growth but is nontoxic to human hepatocytes in chimeric mice. Cancer Res. 64 23 (2004) 8502-8506
    • (2004) Cancer Res. , vol.64 , Issue.23 , pp. 8502-8506
    • Hao, C.1    Song, J.H.2    Hsi, B.3
  • 64
    • 33847167668 scopus 로고    scopus 로고
    • A phase I safety and pharmacokinetic (PK) study of recombinant Apo2L/TRAIL, an apoptosis-inducing protein in patients with advanced cancer
    • Herbst R., Mendolson D., Ebbinghaus S., et al. A phase I safety and pharmacokinetic (PK) study of recombinant Apo2L/TRAIL, an apoptosis-inducing protein in patients with advanced cancer. P. Am. Soc. Clin. Oncol. 24 (2006) 3013
    • (2006) P. Am. Soc. Clin. Oncol. , vol.24 , pp. 3013
    • Herbst, R.1    Mendolson, D.2    Ebbinghaus, S.3
  • 65
    • 0034652486 scopus 로고    scopus 로고
    • Increased death receptor 5 expression by chemotherapeutic agents in human gliomas causes synergistic cytotoxicity with tumor necrosis factor-related apoptosis-inducing ligand in vitro and in vivo
    • Nagane M., Pan G., Weddle J.J., Dixit V.M., Cavenee W.K., and Huang H.J. Increased death receptor 5 expression by chemotherapeutic agents in human gliomas causes synergistic cytotoxicity with tumor necrosis factor-related apoptosis-inducing ligand in vitro and in vivo. Cancer Res. 60 4 (2000) 847-853
    • (2000) Cancer Res. , vol.60 , Issue.4 , pp. 847-853
    • Nagane, M.1    Pan, G.2    Weddle, J.J.3    Dixit, V.M.4    Cavenee, W.K.5    Huang, H.J.6
  • 66
    • 0034985464 scopus 로고    scopus 로고
    • Synergistic induction of apoptosis by the combination of trail and chemotherapy in chemoresistant ovarian cancer cells
    • Cuello M., Ettenberg S.A., Nau M.M., and Lipkowitz S. Synergistic induction of apoptosis by the combination of trail and chemotherapy in chemoresistant ovarian cancer cells. Gynecol. Oncol. 81 3 (2001) 380-390
    • (2001) Gynecol. Oncol. , vol.81 , Issue.3 , pp. 380-390
    • Cuello, M.1    Ettenberg, S.A.2    Nau, M.M.3    Lipkowitz, S.4
  • 67
    • 37149035841 scopus 로고    scopus 로고
    • A phase IB safety and pharmacokinetic (PK) study of recombinant human Apo2L/TRAIL in combination with rituximab in patients with low-grade non-Hodgkin lymphoma
    • Yee L., Fanale K., Dimick S., et al. A phase IB safety and pharmacokinetic (PK) study of recombinant human Apo2L/TRAIL in combination with rituximab in patients with low-grade non-Hodgkin lymphoma. J. Clin. Oncol. 25 No 18S (June 20 Suppl.) (2007) 8078
    • (2007) J. Clin. Oncol. , vol.25 , Issue.No 18S June 20 SUPPL. , pp. 8078
    • Yee, L.1    Fanale, K.2    Dimick, S.3
  • 68
    • 57049120209 scopus 로고    scopus 로고
    • Phase Ib study of recombinant human (rh) Apo2L/TRAIL in combination with paclitaxel, carboplatin, and bevacizumab (PCB) in patients with advanced non-small cell lung cancer (NSCLC)
    • Soria J., Smit E.F., Khayat D., et al. Phase Ib study of recombinant human (rh) Apo2L/TRAIL in combination with paclitaxel, carboplatin, and bevacizumab (PCB) in patients with advanced non-small cell lung cancer (NSCLC). J. Clin. Oncol. 26 No 15S (May 20 Suppl.) (2008) 3539
    • (2008) J. Clin. Oncol. , vol.26 , Issue.No 15S May 20 SUPPL. , pp. 3539
    • Soria, J.1    Smit, E.F.2    Khayat, D.3


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