Early Seroconversion and rapidly increasing autoantibody concentrations predict prepubertal manifestation of type 1 diabetes in Children at genetic risk

Diabetologia

Volumn 55, Issue 7, 2012, Pages 1926-1936

  Parikka, V ^a,b   Nanto Salonen K ^a,b   Saarinen, M ^c   Simell, T ^a   Ilonen, J ^b,d   Hyoty H ^e,f   Veijola, R ^g,h   Knip, M ^f,i,j,k   Simell, O ^a,b  

^a TURKU UNIVERSITY HOSPITAL   (Finland)

^b UNIVERSITY OF TURKU   (Finland)

^c UNIVERSITY OF TURKU   (Finland)

^d UNIVERSITY OF EASTERN FINLAND   (Finland)

^e TAMPERE UNIVERSITY OF TECHNOLOGY   (Finland)

^f TAMPERE UNIVERSITY HOSPITAL   (Finland)

^g OULU UNIVERSITY HOSPITAL   (Finland)

^h UNIVERSITY OF OULU   (Finland)

ⁱ UNIVERSITY OF HELSINKI AND HELSINKI UNIVERSITY HOSPITAL   (Finland)

^j UNIVERSITY OF HELSINKI   (Finland)

^k FOLKHÄLSAN RESEARCH CENTER   (Finland)

more..

Author keywords

Autoantibodies; Gada; Ia 2a; Iaa; Ica; Type 1 diabetes

Indexed keywords

ANTIGEN; AUTOANTIBODY; GLUTAMATE DECARBOXYLASE 65; HLA ANTIGEN; INSULIN; ISLET ANTIGEN 2; UNCLASSIFIED DRUG;

ADOLESCENT; ARTICLE; CHILD; CHILDBIRTH; CONTROLLED STUDY; DISEASE COURSE; FEMALE; FOLLOW UP; GENETIC RISK; HUMAN; INCIDENCE; INSULIN DEPENDENT DIABETES MELLITUS; MAJOR CLINICAL STUDY; MALE; PANCREAS ISLET CELL; PREDICTION; PREPUBERTY; PRESCHOOL CHILD; PRIORITY JOURNAL; PROTEIN ANALYSIS; SCHOOL CHILD; SEROCONVERSION;

AGE OF ONSET; AUTOANTIBODIES; BIOLOGICAL MARKERS; CHILD, PRESCHOOL; DIABETES MELLITUS, TYPE 1; DISEASE PROGRESSION; DISEASE SUSCEPTIBILITY; FEMALE; FINLAND; HLA ANTIGENS; HUMANS; INFANT; INFANT, NEWBORN; MALE; PREDIABETIC STATE; PREDICTIVE VALUE OF TESTS; PREGNANCY;

EID: 84866382555     PISSN: 0012186X     EISSN: 14320428     Source Type: Journal    
DOI: 10.1007/s00125-012-2523-3     Document Type: Article

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