A novel micro-assay for insulin autoantibodies

Journal of Autoimmunity

Volumn 10, Issue 5, 1997, Pages 473-478

  Williams, Alistair J K ^a   Bingley, Polly J ^a   Bonifacio, Ezio ^b   Palmer, Jerry P ^c   Gale, Edwin A M ^a  

^a UNIVERSITY OF BRISTOL   (United Kingdom)

^b SAN RAFFAELE HOSPITAL   (Italy)

^c UNIVERSITY OF WASHINGTON   (United States)

Author keywords

Autoantibodies; Insulin autoantibodies; Prediction; Type 1 (insulin dependent) diabetes mellitus

Indexed keywords

AUTOANTIBODY; INSULIN ANTIBODY;

ADOLESCENT; ADULT; ANTIBODY DETECTION; ARTICLE; AUTOIMMUNITY; CHILD; CONTROLLED STUDY; HUMAN; IMMUNOASSAY; INSULIN DEPENDENT DIABETES MELLITUS; MAJOR CLINICAL STUDY; MASS SCREENING; PRIORITY JOURNAL; SCHOOL CHILD; SCREENING TEST;

EID: 0030798560     PISSN: 08968411     EISSN: None     Source Type: Journal    
DOI: 10.1006/jaut.1997.0154     Document Type: Article

References (22)

1. Palmer J.P., Asplin C.M., Clemons P., Lyen K., Tatpati O., Raghu P.K., Paquette T.L. Insulin antibodies in insulin dependent diabetes before insulin treatment. Science. 222:1983;1337-1339.
2. Soeldner J.S., Tuttleman M., Srikanta S., Ganda O.P., Eisenbarth G.S. Insulin-dependent diabetes mellitus and autoimmunity: islet-cell autoantibodies, insulin autoantibodies, and beta-cell failure. N. Engl. J. Med. 313:1985;893-894.
3. Vardi P., Dib S.A., Tuttleman M., Connelly J.E., Grindbergs M., Radizabeh A., Riley W.J., Maclaren N.K., Eisenbarth G.S., Soeldner J.S. Competitive insulin autoantibody assay. Prospective evaluation of subjects at high risk for development of type 1 diabetes mellitus. Diabetes. 36:1987;1286-1291.
4. Bosi E., Becker F., Bonifacio E., Wagner R., Collins P., Gale E.A.M., Bottazzo G.F. Progression to type 1 diabetes in autoimmune endocrine patients with islet cell antibodies. Diabetes. 40:1991;977-984.
5. Hegewald M.J., Schoenfeld S.L., McCulloch D.K., Greenbaum C.J., Klaff L.J., Palmer J.P. Increased specificity and sensitivity of insulin antibody measurements in autoimmune thyroid disease and type 1 diabetes. J. Immunol. Methods. 154:1992;61-68.
6. Schatz D., Krischer J., Horne G., Riley W., Spillar R., Silverstein J., Winter W., Muir A., Derovanesian D., Shah S., Malone J., Maclaren N. Islet cell antibodies predict insulin-dependent diabetes in United States school age children as powerfully as in unaffected relatives. J. Clin. Invest. 93:1994;2403-2407.
7. Arslanian S.A., Becker D.J., Rabin B., Atchison R., Eberhardt M., Cavender D., Dorman J., Drash A.L. Correlates of insulin antibodies in newly diagnosed children with insulin-dependent diabetes before insulin therapy. Diabetes. 34:1985;926-930.
8. Vardi P., Ziegler A.G., Mathews J.H., Dib S., Keller R.J., Ricker A.T., Wolfsdorf J.I., Herskowitz R.D., Rabizadeh A., Eisenbarth G.S., Soeldner J.S. Concentration of insulin autoantibodies at onset of Type 1 diabetes: inverse correlation with age. Diabetes Care. 11:1988;736-739.
9. Kurtz A.B., Mathews J.A., Mustaffa B.E., Daggett P.R., Nabarro J.D.N. Decrease of antibodies to insulin, proinsulin and contaminating hormones after changing treatment from conventional beef to purified pork insulin. Diabetologia. 18:1980;147-150.
10. Wilkin T.J., Nicholson S., Casey C. A micro-enzyme linked immunosorbent assay for insulin antibodies in serum. J. Immunol. Methods. 76:1985;185-194.
11. Greenbaum C.J., Palmer J.P., Kuglin B., Kolb H. Insulin autoantibodies measured by radioimmunoassay methodology are more related to insulin-dependent diabetes mellitus than those measured by enzyme-linked immunosorbent assay: results of the fourth international workshop on the standardization of insulin autoantibody measurement. J. Clin. Endocrinol. Metab. 74:1992;1040-1044.
12. Bingley P.J., Bonifacio E., Shattock M., Gillmor H.A., Sawtell P.A., Dunger D.B., Scott R.D.M., Bottazzo G.F., Gale E.A.M. Can islet cell antibodies predict IDDM in the general population? Diabetes Care. 16:1993;45-50.
13. Kurtz A.B., DiSilvio L., Bosi E. The determination of detection limits for insulin antibody assays. Diabetologia. 31:1988;395-399.
14. Zweig M.H., Campbell G. Receiver-Operating Characteristic (ROC) plots. A fundamental evaluation tool in clinical medicine. Clin. Chem. 39:1993;561-577.
15. Bingley P.J., ICARUS Group. Interactions of age, islet cell antibodies, insulin autoantibodies and first phase insulin response in predicting risk of progression to IDDM in ICA positive relatives: the ICARUS dataset. Diabetes. 45:1996;1720-1728.
16. 65. Diabetes. 43:1994;459-467.
17. Bonifacio E., Lampasona V., Genovese S., Ferrari M., Bosi E. Identification of protein tyrosine phosphatase-like IA2 (islet cell antigen 512) as the insulin-dependent diabetes-related 37/40K autoantigen and a target of islet-cell antibodies. J. Immunol. 155:1995;5419-5426.
18. Payton M.A., Hawkes C.J., Christie M.R. Relationship of the 37,000- and the 40,000-Mr tryptic fragments of islet antigens in insulin-dependent diabetes to the protein tyrosine phosphatase-like molecule IA-2 (ICA512). J. Clin. Invest. 96:1995;1506-1511.
19. Chevenne D., Valade F., Bridel M.-P., Rigal O., Demellier J.-F., Sachs C., Porquet D. Protein A-Sepharose used to measure free insulin in plasma. Clin. Chem. 37:1991;64-67.
20. Bilbao J.R., Calvo B., Urrutia I., Linares A., Castano L. Anti-insulin activity in normal newborn cord-blood serum. Absence of IgG-mediated insulin binding. Diabetes. 46:1997;713-716.
21. Kronvall G., Williams R.C. Differences in anti-protein A activity among IgG subgroups. J. Immunol. 103:1969;828-833.
22. Koch M., Francois-Gerard C., Sodoyez-Goffaux F., Sodoyez J.-C. Semi-quantitative assessment of anti-insulin total IgG and IgG sub-classes in insulin-immunized patients using a highly sensitive immunochemical micromethod. Diabetologia. 29:1986;720-726.