Relationship of transcription factor 7 like 2 gene rs7903146 variation with type 2 diabetes and obesity related parameters

Diabetes and Metabolic Syndrome: Clinical Research and Reviews

Volumn 6, Issue 1, 2012, Pages 48-53

  Kahveci, Cigdem ^a   Koldemir, Meliha ^a   Cagatay, Penbe ^b   Bayer, Hikmet ^c   Yildiz, Sema ^c   Bagriacik, Nazif ^c   Duman, Belgin Susleyici ^a  

^a MARMARA UNIVERSITY   (Turkey)

^b ISTANBUL UNIVERSITY   (Turkey)

^c Private Diabetes Hospital   (Turkey)

Author keywords

Fat mass; Insulin resistance; Obesity; rs7903146 polymorphism; Serum lipids; TCF7L2

Indexed keywords

GLUCOSE; INSULIN; TRANSCRIPTION FACTOR 7 LIKE 2;

ADULT; AGED; BODY HEIGHT; BODY WEIGHT; CASE CONTROL STUDY; CONTROLLED STUDY; DIABETIC PATIENT; FEMALE; GENE FREQUENCY; GENETIC ASSOCIATION; GENOTYPE; GLUCOSE BLOOD LEVEL; HETEROZYGOTE; HOMEOSTATIC MODEL ASSESSMENT; HOMOZYGOTE; HUMAN; HYPERTENSION; INSULIN BLOOD LEVEL; INSULIN RESISTANCE; LEAN BODY WEIGHT; MAJOR CLINICAL STUDY; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; OBESITY; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; REVIEW; SCORING SYSTEM; SINGLE NUCLEOTIDE POLYMORPHISM; WILD TYPE;

EID: 84866373400     PISSN: 18714021     EISSN: 18780334     Source Type: Journal    
DOI: 10.1016/j.dsx.2012.05.002     Document Type: Article

References (44)

1. A. Duval, M. Busson-Leconiat, and R. Berger Assignment of the TCF-4 gene (TCF7L2) to human chromosome band 10q25.3 Cytogenetics and Cell Genetics 88 2000 264 265
2. S.F. Grant, G. Thorleifsson, I. Reynisdottir, R. Benediktsson, A. Manolescu, and J. Sainz Variant of transcription factor 7-like 2 (TCF7L2) gene confers risk of type 2 diabetes Nature Genetics 38 2006 320 323
3. S. Papadopoulou, and H. Edlund Attenuated Wnt signaling perturbs pancreatic growth but not pancreatic function Diabetes 54 2005 2844 2851
4. A. Helgason, S. Pálsson, G. Thorleifsson, S.F. Grant, V. Emilsson, and S. Gunnarsdottir TCF7L2 gene variants on type 2 diabetes and adaptive evolution Nature Genetics 39 2007 218 225
5. C. Prunier, B.A. Hocevar, and P.H. Howe Wnt signaling: physiology and pathology Growth Factors 22 2004 141 150
6. F. Yi, P.L. Brubaker, and T. Jin TCF-4 mediates cell type-specific regulation of proglucagon gene expression by beta-catenin and glycogen synthase kinase-3beta Journal of Biological Chemistry 280 2004 1457 1464
7. A. Duval, S. Rolland, E. Tubacher, H. Bui, G. Thomas, and R. Hamelin The human T-cell transcription factor-4 gene: structure, extensive characterization of alternative splicings, and mutational analysis in colorectal cancer cell lines Cancer Research 60 2000 3872 3879
8. M.M. Sale, S.G. Smith, J.C. Mychaleckyj, K.L. Keene, C.D. Langefeld, and T.S. Leak Variants of the transcription factor 7-like 2 (TCF7L2) gene are associated with type 2 diabetes in an African-American population enriched for nephropathy Diabetes 56 2007 2638 2642
9. T. Guo, R.L. Hanson, M. Traurig, Y.L. Muller, L. Ma, and J. Mack TCF7L2 is not a major susceptibility gene for type 2 diabetes in Pima Indians: analysis of 3,501 individuals Diabetes 56 2007 3082 3088
10. C. Zhang, L. Qi, D.J. Hunter, J.B. Meigs, J.E. Manson, and R.M. van Dam Variant of transcription factor 7-like 2 (TCF7L2) gene and the risk of type 2 diabetes in large cohorts of U.S. women and men Diabetes 55 2006 2645 2648
11. L.J. Scott, L.L. Bonnycastle, C.J. Willer, A.G. Sprau, A.U. Jackson, and N. Narisu Association of transcription factor 7-like 2 (TCF7L2) variants with type 2 diabetes in a Finnish sample Diabetes 55 2006 2649 2653
12. M.C. Ng, C.H. Tam, V.K. Lam, W.Y. So, R.C. Ma, and J.C. Chan Replication and identification of novel variants at TCF7L2 associated with type 2 diabetes in Hong Kong Chinese Journal of Clinical Endocrinology and Metabolism 92 2007 3733 3737
13. S. Cauchi, D. Meyre, C. Dina, H. Choquet, C. Samson, and S. Gallina Transcription factor TCF7L2 genetic study in the French population: expression in human beta-cells and adipose tissue and strong association with type 2 diabetes Diabetes 55 2006 2903 2908
14. N.M. De Silva, A. Steele, B. Shields, B. Knight, K. Parnell, and M.N. Weedon The transcription factor 7-like 2 (TCF7L2) gene is associated with type 2 diabetes in UK community-based cases, but the risk allele frequency is reduced compared with UK cases selected for genetic studies Diabetic Medicine 24 2007 1067 1072
15. Y. Luo, H. Wang, X. Han, Q. Ren, F. Wang, and X. Zhang Meta-analysis of the association between SNPs in TCF7L2 and type 2 diabetes in East Asian population Diabetes Research and Clinical Practice 85 2009 139 146
16. S. Mayans, K. Lackovic, P. Lindgren, K. Ruikka, A. Agren, and M. Eliasson TCF7L2 polymorphisms are associated with type 2 diabetes in northern Sweden European Journal of Human Genetics 15 2007 342 346
17. G.F. Marquezine, A.C. Pereira, A.G. Sousa, J.G. Mill, W.A. Hueb, and J.E. Krieger TCF7L2 variant genotypes and type 2 diabetes risk in Brazil: significant association, but not a significant tool for risk stratification in the general population BMC Medical Genetics 9 2008 1471 2350
18. G.F. Marquezine, A.C. Pereira, A.G. Sousa, J.G. Mill, W.A. Hueb, and J.E. Krieger TCF7L2 gene is associated with type 2 diabetes in Polish population Diabetologia Doświadczalna i Kliniczna 7 2007 109 111
19. D.S. Rees, S. Bellary, and C.A. Britten Common variants of the TCF7L2 gene are associated with increased risk of type 2 diabetes mellitus in a UK-resident South Asian population BMC Medical Genetics 9 2008 1471 2350
20. T. Hayashi, Y. Iwamoto, K. Kaku, H. Hirose, and S. Maeda Replication study for the association of TCF7L2 with susceptibility to type 2 diabetes in a Japanese population Diabetologia 50 2007 980 984
21. M. Horikoshi, K. Hara, C. Ito, R. Nagai, P. Froguel, and T. Kadowaki A genetic variation of the transcription factor 7-like 2 gene is associated with risk of type 2 diabetes in the Japanese population Diabetologia 50 2007 747 751
22. J.A. Kennell, and O.A. MacDougald Wnt signaling inhibits adipogenesis through beta catenin-dependent and independent mechanisms Journal of Biological Chemistry 280 2005 24004 24010
23. J.C. Florez, K.A. Jablonski, N. Bayley, T.I. Pollin, P.I. de Bakker, and A.R. Shuldiner TCF7L2 polymorphisms and progression to diabetes in the Diabetes Prevention Program The New England Journal of Medicine 355 2006 241 250
24. C.M. Damcott, T.I. Pollin, L.J. Reinhart, S.H. Ott, H. Shen, and K.D. Silver Polymorphisms in the transcription factor 7 like 2 (TCF7L2) gene are associated with type 2 diabetes in the Amish: replication and evidence for a role in both insulin secretion and insulin resistance Diabetes 55 2006 2654 2659
25. J. Munoz, K.H. Lok, B.A. Gower, J.R. Fernandez, G.R. Hunter, and C. Lara-Castro Polymorphism in the transcription factor 7-like 2 (TCF7L2) gene is associated with reduced insulin secretion in nondiabetic women Diabetes 55 2006 3630 3634
26. World Health Organization Definition, diagnosis and classification of diabetes mellitus and its complications 1999 World Health Organization Geneva
27. K.G. Alberti, P. Zimmet, J. Shaw IDF Epidemiology Task Force Consensus Group The metabolic syndrome: a new worldwide definition Lancet 366 2005 1059 1062
28. J.P. Hosker, D.R. Matthews, A.S. Rudenski, M.A. Burnett, P. Darling, and E.G. Bown Continuous infusion of glucose with model assessment: measurement of insulin and β-cell function in man Diabetologia 28 1985 401 411
29. D.R. Matthews, J.P. Hosker, A.S. Rudenski, B.A. Naylor, D.F. Treacher, and R.C. Turner Homeostasis model assessment: insulin resistance and β-cell function from fasting plasma glucose and insulin concentrations in man Diabetologia 28 1985 412 419
30. E. Bonora, G. Targher, M. Alberiche, R.C. Bonadonna, F. Saggiani, and M.B. Zenere Homeostasis model assessment closely mirrors the glucose clamp technique in the assessment of insulin sensitivity: studies in subjects with various degrees of glucose tolerance and insulin sensitivity Diabetes Care 23 2000 57 63
31. M. Matsuda, and R.A. DeFronzo Insulin sensitivity indices obtained from oral glucose tolerance testing: comparison with the euglycemic insulin clamp Diabetes Care 22 1999 1462 1470
32. R. Hume Prediction of lean body mass from height and weight Journal of Clinical Pathology 19 1966 389 395
33. S.A. Miller, D.D. Dykes, and H.F. Polesky A simple salting out procedure for extracting DNA from human nucleated cells Nucleic Acids Research 16 1988 1215
34. Y. Tong, Y. Lin, Y. Zhang, J. Yang, Y. Zhang, and H. Liu Association between TCF7L2 gene polymorphisms and susceptibility to type 2 diabetes mellitus: a large Human Genome Epidemiology (HuGE) review and meta-analysis BMC Medical Genetics 10 2009 1471 2350
35. D. Bodhini, V. Radha, M. Dhar, N. Narayani, and V. Mohan rs12255372 (G/T) and rs7903146 (C/T) polymorphisms of the TCF7L2 gene are associated with type 2 diabetes mellitus in Asian Indians Metabolism Clinical and Experimental 56 2007 1174 1178
36. R. Saxena, L. Gianniny, N.P. Burtt, V. Lyssenko, C. Giuducci, and M. Sjögren Common single nucleotide polymorphisms in TCF7L2 are reproducibly associated with type 2 diabetes and reduce the insulin response to glucose in nondiabetic individuals Diabetes 55 2006 2890 2895
37. O. Alsmadi, K. Al-Rubeaan, G. Mohamed, F. Alkayal, H. Al-Saud, and N.A. Al-Saud Weak or no association of TCF7L2 variants with type 2 diabetes risk in an Arab population BMC Medical Genetics 9 9 2008 72
38. H. Saadi, N. Nagelkerke, S.G. Carruthers, S. Benedict, S. Abdulkhalek, and R. Reed Association of TCF7L2 polymorphism with diabetes mellitus, metabolic syndrome and markers of beta cell function and insulin resistance in a population based sample of Emirati subjects Diabetes Research and Clinical Practice 80 2008 392 398
39. J. Delgado-Lista, P. Perez-Martinez, A. García-Rios, C.M. Phillips, C.M. Williams, and H.L. Gulseth Pleiotropic effects of TCF7L2 gene variants and its modulation in the metabolic syndrome: from the LIPGENE study Atherosclerosis 214 2011 110 116
40. A. Muendlein, C.H. Saely, S. Geller-Rhomberg, G. Sonderegger, P. Rein, and T. Winder Single nucleotide polymorphisms of TCF7L2 are linked to diabetic coronary atherosclerosis PLoS One 6 2011 e17978
41. Y. Yan, R. Klein, G. Heiss, C.J. Girman, E.M. Lange, and B.E. Klein The transcription factor 7-like 2 (TCF7L2) polymorphism may be associated with focal arteriolar narrowing in Caucasians with hypertension or without diabetes: the ARIC Study BMC Endocrine Disorders 10 2010 9
42. R.J.F. Loos, P.W. Franks, and R.W. Francis TCF7L2 polymorphisms modulate proinsulin levels and β-cell function in a British Europid population Diabetes 56 2007 1943 1947
43. J. Wang, J. Kuusisto, M. Vänttinen, T. Kuulasmaa, J. Lindström, and J. Tuomilehto Variants of transcription factor 7 like 2 (TCF7L2) gene predict conversion to type 2 diabetes in the Finnish Diabetes Prevention study and are associated with impaired glucose regulation and impaired secretion Diabetologia 50 2007 1192 1200
44. L.J. Rasmussen-Torvik, J.S. Pankow, D.R. Jacobs Jr., and A.R. Sinaiko Preliminary report: no association between TCF7L2 rs7903146 and euglycemic-clamp-derived insulin sensitivity in a mixed-age cohort Metabolism Clinical and Experimental 58 2009 1369 1371