-
2
-
-
0034463222
-
Mechanistic insights on the inhibition of tumor angiogenesis
-
Jiménez B, Volpert OV (2001) Mechanistic insights on the inhibition of tumor angiogenesis. J Mol Med 78(12):663-672
-
(2001)
J Mol Med
, vol.78
, Issue.12
, pp. 663-672
-
-
Jiménez, B.1
Volpert, O.V.2
-
3
-
-
14644440555
-
Role of the vascular endothelial growth factor pathway in tumor growth and angiogenesis
-
DOI 10.1200/JCO.2005.06.081
-
Hicklin DJ, Ellis LM (2005) Role of the vascular endothelial growth factor pathway in tumor growth and angiogenesis. J Clin Oncol 23(5):1011-1027 (Pubitemid 46202320)
-
(2005)
Journal of Clinical Oncology
, vol.23
, Issue.5
, pp. 1011-1027
-
-
Hicklin, D.J.1
Ellis, L.M.2
-
4
-
-
34548443831
-
Vascular endothelial growth factor receptor-2: Structure, function, intracellular signalling and therapeutic inhibition
-
DOI 10.1016/j.cellsig.2007.05.013, PII S0898656807001532
-
Holmes K, Roberts OL, Thomas AM, Cross MJ (2007) Vascular endothelial growth factor receptor-2: structure, function, intracellular signalling and therapeutic inhibition. Cell Signal 19(10):2003-2012 (Pubitemid 47354167)
-
(2007)
Cellular Signalling
, vol.19
, Issue.10
, pp. 2003-2012
-
-
Holmes, K.1
Roberts, O.L.2
Thomas, A.M.3
Cross, M.J.4
-
5
-
-
0034653482
-
Characterization of the vasculogenic block in the absence of vascular endothelial growth factor-A
-
Bautch VL, Redick SD, Scalia A, Harmaty M, Carmeliet P, Rapoport R (2000) Characterization of the vasculogenic block in the absence of vascular endothelial growth factor-A. Blood 95(6): 1979-1987 (Pubitemid 30151635)
-
(2000)
Blood
, vol.95
, Issue.6
, pp. 1979-1987
-
-
Bautch, V.L.1
Redick, S.D.2
Scalia, A.3
Harmaty, M.4
Carmeliet, P.5
Rapoport, R.6
-
6
-
-
0029021660
-
Role of the Flt-1 receptor tyrosine kinase in regulating the assembly of vascular endothelium
-
Fong G-H, Rossant J, Gertsenstein M, Breitman ML (1995) Role of the Flt-1 receptor tyrosine kinase in regulating the assembly of vascular endothelium. Nature 376(6535):66-70
-
(1995)
Nature
, vol.376
, Issue.6535
, pp. 66-70
-
-
Fong, G.-H.1
Rossant, J.2
Gertsenstein, M.3
Breitman, M.L.4
-
7
-
-
0029006696
-
Failure of blood-island formation and vasculogenesis in Flk-1-deficient mice
-
Shalaby F, Rossant J, Yamaguchi TP et al (1995) Failure of blood-island formation and vasculogenesis in Flk-1-deficient mice. Nature 376(6535):62-66
-
(1995)
Nature
, vol.376
, Issue.6535
, pp. 62-66
-
-
Shalaby, F.1
Rossant, J.2
Yamaguchi, T.P.3
-
8
-
-
0033917495
-
Vascular apoptosis and involution in gliomas precede neovascularization: A novel concept for glioma growth and angiogenesis
-
Zagzag D, Amirnovin R, Greco MA et al (2000) Vascular apoptosis and involution in gliomas precede neovascularization: a novel concept for glioma growth and angiogenesis. Lab Invest 80(6):837-849 (Pubitemid 30421801)
-
(2000)
Laboratory Investigation
, vol.80
, Issue.6
, pp. 837-849
-
-
Zagzag, D.1
Amirnovin, R.2
Greco, M.A.3
Yee, H.4
Holash, J.5
Wiegand, S.J.6
Zabski, S.7
Yancopoulos, G.D.8
Grumet, M.9
-
9
-
-
33751256842
-
Hypoxia-inducible factor 1 and VEGF upregulate CXCR4 in glioblastoma: Implications for angiogenesis and glioma cell invasion
-
DOI 10.1038/labinvest.3700482, PII 3700482
-
Zagzag D, Lukyanov Y, Lan L et al (2006) Hypoxia-inducible factor 1 and VEGF upregulate CXCR4 in glioblastoma: implications for angiogenesis and glioma cell invasion. Lab Invest 86(12):1221-1232 (Pubitemid 44789912)
-
(2006)
Laboratory Investigation
, vol.86
, Issue.12
, pp. 1221-1232
-
-
Zagzag, D.1
Lukyanov, Y.2
Lan, L.3
Ali, M.A.4
Esencay, M.5
Mendez, O.6
Yee, H.7
Voura, E.B.8
Newcomb, E.W.9
-
10
-
-
36049037819
-
Bevacizumab plus irinotecan in recurrent glioblastoma multiforme
-
DOI 10.1200/JCO.2007.12.2440
-
Vredenburgh J, Desjardins A, Herndon J et al (2007) Bevacizumab plus irinotecan in recurrent glioblastoma multiforme. J Clin Oncol 25:4722-4729 (Pubitemid 350086473)
-
(2007)
Journal of Clinical Oncology
, vol.25
, Issue.30
, pp. 4722-4729
-
-
Vredenburgh, J.J.1
Desjardins, A.2
Herndon II, J.E.3
Marcello, J.4
Reardon, D.A.5
Quinn, J.A.6
Rich, J.N.7
Sathornsumetee, S.8
Gururangan, S.9
Sampson, J.10
Wagner, M.11
Bailey, L.12
Bigner, D.D.13
Friedman, A.H.14
Friedman, H.S.15
-
11
-
-
70350461699
-
Bevacizumab alone and in combination with irinotecan in recurrent glioblastoma
-
Friedman HS, Prados MD, Wen PY et al (2009) Bevacizumab alone and in combination with irinotecan in recurrent glioblastoma. J Clin Oncol 27(28):4733-4740
-
(2009)
J Clin Oncol
, vol.27
, Issue.28
, pp. 4733-4740
-
-
Friedman, H.S.1
Prados, M.D.2
Wen, P.Y.3
-
12
-
-
65249185501
-
Bevacizumab and chemotherapy for recurrent glioblastoma
-
Nghiemphu PL, Liu W et al (2009) Bevacizumab and chemotherapy for recurrent glioblastoma. Neurology 72(14):1217-1222
-
(2009)
Neurology
, vol.72
, Issue.14
, pp. 1217-1222
-
-
Nghiemphu, P.L.1
Liu, W.2
-
13
-
-
54749092522
-
Flt-1 signaling in macrophages promotes glioma growth in vivo
-
Kerber M, Reiss Y et al (2008) Flt-1 signaling in macrophages promotes glioma growth in vivo. Cancer Res 68(18):7342-7351
-
(2008)
Cancer Res
, vol.68
, Issue.18
, pp. 7342-7351
-
-
Kerber, M.1
Reiss, Y.2
-
14
-
-
0035866771
-
Inhibition of vascular endothelial growth factor receptor signaling leads to reversal of tumor resistance to radiotherapy
-
Geng L, Donnelly E et al (2001) Inhibition of vascular endothelial growth factor receptor signaling leads to reversal of tumor resistance to radiotherapy. Cancer Res 61(6):2413-2419 (Pubitemid 32685816)
-
(2001)
Cancer Research
, vol.61
, Issue.6
, pp. 2413-2419
-
-
Geng, L.1
Donnelly, E.2
McMahon, G.3
Lin, P.C.4
Sierra-Rivera, E.5
Oshinka, H.6
Hallahan, D.E.7
-
15
-
-
0031035753
-
Expression and distribution of vascular endothelial growth factor protein in human brain tumors
-
DOI 10.1007/s004010050591
-
Pietsch T, Valter MM, Wolf HK et al (1997) Expression and distribution of vascular endothelial growth factor protein in human brain tumors. Acta Neuropathol 93(2):109-117 (Pubitemid 27060902)
-
(1997)
Acta Neuropathologica
, vol.93
, Issue.2
, pp. 109-117
-
-
Pietsch, T.1
Valter, M.M.2
Wolf, H.K.3
Von Deimling, A.4
Su Huang, H.-J.5
Cavenee, W.K.6
Wiestler, O.D.7
-
16
-
-
12344250947
-
VEGF and VEGF receptor-1 concentration in vestibular schwannoma homogenates correlates to tumor growth rate
-
DOI 10.1097/00129492-200501000-00017
-
Caye-Thomasen P et al (2005) VEGF and VEGF receptor-1 concentration in vestibular schwannoma homogenates correlates to tumor growth rate. [Miscellaneous Article]. Otol Neurotol 26(1):98-101 (Pubitemid 40130217)
-
(2005)
Otology and Neurotology
, vol.26
, Issue.1
, pp. 98-101
-
-
Caye-Thomasen, P.1
Werther, K.2
Nalla, A.3
Bog-Hansen, T.C.4
Nielsen, H.J.5
Stangerup, S.-E.6
Thomsen, J.7
-
17
-
-
0142243109
-
Roles of PDGF in animal development
-
DOI 10.1242/dev.00721
-
Hoch RV, Soriano P (2003) Roles of PDGF in animal development. Development 130(20):4769-4784 (Pubitemid 37321862)
-
(2003)
Development
, vol.130
, Issue.20
, pp. 4769-4784
-
-
Hoch, R.V.1
Soriano, P.2
-
18
-
-
44149090296
-
Role of platelet-derived growth factors in physiology and medicine
-
DOI 10.1101/gad.1653708
-
Andrae J, Gallini R et al (2008) Role of platelet-derived growth factors in physiology and medicine. Genes Dev 22(10):1276-1312 (Pubitemid 351717519)
-
(2008)
Genes and Development
, vol.22
, Issue.10
, pp. 1276-1312
-
-
Andrae, J.1
Gallini, R.2
Betsholtz, C.3
-
19
-
-
75349091751
-
Perivascular nitric oxide activates notch signaling and promotes stem-like character in PDGFinduced glioma cells
-
Charles N, Ozawa T et al (2010) Perivascular nitric oxide activates notch signaling and promotes stem-like character in PDGFinduced glioma cells. Cell Stem Cell 6(2):141-152
-
(2010)
Cell Stem Cell
, vol.6
, Issue.2
, pp. 141-152
-
-
Charles, N.1
Ozawa, T.2
-
20
-
-
0036645057
-
Platelet-derived growth factor (PDGF) autocrine signaling regulates survival and mitogenic pathways in glioblastoma cells
-
Lokker NA, Sullivan CM et al (2002) Platelet-derived growth factor (PDGF) autocrine signaling regulates survival and mitogenic pathways in glioblastoma cells. Cancer Res 62(13):3729-3735
-
(2002)
Cancer Res
, vol.62
, Issue.13
, pp. 3729-3735
-
-
Lokker, N.A.1
Sullivan, C.M.2
-
21
-
-
0037145037
-
Integrins: Bidirectional, allosteric signaling machines
-
DOI 10.1016/S0092-8674(02)00971-6
-
Hynes RO (2002) Integrins: bidirectional, allosteric signaling machines. Cell 110(6):673-687 (Pubitemid 35283958)
-
(2002)
Cell
, vol.110
, Issue.6
, pp. 673-687
-
-
Hynes, R.O.1
-
22
-
-
77955378377
-
Mesenchymal migration as a therapeutic target in glioblastoma
-
Zhong J, Paul A et al (2010) Mesenchymal migration as a therapeutic target in glioblastoma. J Oncol 2010(21):430142
-
(2010)
J Oncol
, vol.2010
, Issue.21
, pp. 430142
-
-
Zhong, J.1
Paul, A.2
-
23
-
-
33845992903
-
Intracranial microenvironment reveals independent opposing functions of host αVβ3 expression on glioma growth and angiogenesis
-
DOI 10.1074/jbc.M605344200
-
Kanamori M, Kawaguchi T et al (2006) Intracranial microenvironment reveals independent opposing functions of host αVβ3 expression on glioma growth and angiogenesis. J Biol Chem 281(48):37256-37264 (Pubitemid 46042194)
-
(2006)
Journal of Biological Chemistry
, vol.281
, Issue.48
, pp. 37256-37264
-
-
Kanamori, M.1
Kawaguchi, T.2
Berger, M.S.3
Pieper, R.O.4
-
24
-
-
44649103829
-
3 in gliomas correlates with tumor grade and is not restricted to tumor vasculature
-
DOI 10.1111/j.1750-3639.2008.00137.x
-
Schnell O, Krebs B et al (2008) Expression of integrin avb3 in gliomas correlates with tumor grade and is not restricted to tumor vasculature. Brain Patho 18(3):378-386 (Pubitemid 351782847)
-
(2008)
Brain Pathology
, vol.18
, Issue.3
, pp. 378-386
-
-
Schnell, O.1
Krebs, B.2
Wagner, E.3
Romagna, A.4
Beer, A.J.5
Grau, S.J.6
Thon, N.7
Goetz, C.8
Kretzschmar, H.A.9
Tonn, J.-C.10
Goldbrunner, R.H.11
-
25
-
-
0035513543
-
Brain metastases: Biology and the role of the brain microenvironment
-
Puduvalli V (2001) Brain metastases: biology and the role of the brain microenvironment. Curr Oncol Rep 3(6):467-475
-
(2001)
Curr Oncol Rep
, vol.3
, Issue.6
, pp. 467-475
-
-
Puduvalli, V.1
-
26
-
-
0034319184
-
Molecular mechanisms of tumor dissemination in primary and metastatic brain cancers
-
DOI 10.1016/S0361-9230(00)00379-8, PII S0361923000003798
-
Weber GF, Ashkar S (2000) Molecular mechanisms of tumor dissemination in primary and metastatic brain cancers. Brain Res Bull 53(4):421-424 (Pubitemid 32000819)
-
(2000)
Brain Research Bulletin
, vol.53
, Issue.4
, pp. 421-424
-
-
Weber, G.F.1
Ashkar, S.2
-
27
-
-
33746812188
-
Histone deacetylase enzymes as potential drug targets in cancer and parasitic diseases
-
Ouaissi M, Ouaissi A (2006) Histone deacetylase enzymes as potential drug targets in cancer and parasitic diseases. J Biomed Biotechnol 2006:13474
-
(2006)
J Biomed Biotechnol
, vol.2006
, pp. 13474
-
-
Ouaissi, M.1
Ouaissi, A.2
-
28
-
-
79952085666
-
Expression of nuclear receptor corepressors and class i histone deacetylases in astrocytic gliomas
-
Campos B, Bermejo JL et al (2011) Expression of nuclear receptor corepressors and class I histone deacetylases in astrocytic gliomas. Cancer Sci 102(2):387-392
-
(2011)
Cancer Sci
, vol.102
, Issue.2
, pp. 387-392
-
-
Campos, B.1
Bermejo, J.L.2
-
29
-
-
77957120976
-
HDAC inhibitor, scriptaid, induces glioma cell apoptosis through JNK activation and inhibits telomerase activity
-
Sharma V, Koul N et al (2010) HDAC inhibitor, scriptaid, induces glioma cell apoptosis through JNK activation and inhibits telomerase activity. J Cell Mol Med 14(8):2151-2161
-
(2010)
J Cell Mol Med
, vol.14
, Issue.8
, pp. 2151-2161
-
-
Sharma, V.1
Koul, N.2
-
30
-
-
79960740604
-
Development of a brain metastatic canine prostate cancer cell line
-
Thudi NK, Shu ST et al (2011) Development of a brain metastatic canine prostate cancer cell line. Prostate 71(12):1251-1263
-
(2011)
Prostate
, vol.71
, Issue.12
, pp. 1251-1263
-
-
Thudi, N.K.1
Shu, S.T.2
-
31
-
-
33947191055
-
Phase II trial of bevacizumab and irinotecan in recurrent malignant glioma
-
DOI 10.1158/1078-0432.CCR-06-2309
-
Vredenburgh JJ, Desjardins A et al (2007) Phase II trial of bevacizumab and irinotecan in recurrent malignant glioma. Clin Cancer Res 13(4):1253-1259 (Pubitemid 46424067)
-
(2007)
Clinical Cancer Research
, vol.13
, Issue.4
, pp. 1253-1259
-
-
Vredenburgh, J.J.1
Desjardins, A.2
Herndon II, J.E.3
Dowell, J.M.4
Reardon, D.A.5
Quinn, J.A.6
Rich, J.N.7
Sathornsumetee, S.8
Gururangan, S.9
Wagner, M.10
Bigner, D.D.11
Friedman, A.H.12
Friedman, H.S.13
-
32
-
-
59949083263
-
Phase II trial of single-agent bevacizumab followed by bevacizumab plus irinotecan at tumor progression in recurrent glioblastoma
-
Kreisl TN, Kim L et al (2009) Phase II trial of single-agent bevacizumab followed by bevacizumab plus irinotecan at tumor progression in recurrent glioblastoma. J Clin Oncol 27(5):740-745
-
(2009)
J Clin Oncol
, vol.27
, Issue.5
, pp. 740-745
-
-
Kreisl, T.N.1
Kim, L.2
-
33
-
-
60649116273
-
Antiangiogenic therapy using bevacizumab in recurrent high-grade glioma: Impact on local control and patient survival
-
Narayana A, Kelly P et al (2009) Antiangiogenic therapy using bevacizumab in recurrent high-grade glioma: impact on local control and patient survival. J Neurosurgery 110(1):173-180
-
(2009)
J Neurosurgery
, vol.110
, Issue.1
, pp. 173-180
-
-
Narayana, A.1
Kelly, P.2
-
34
-
-
41649112610
-
Bevacizumab for recurrent malignant gliomas
-
Norden AD, Young GS et al (2008) Bevacizumab for recurrent malignant gliomas. Neurology 70(10):779-787
-
(2008)
Neurology
, vol.70
, Issue.10
, pp. 779-787
-
-
Norden, A.D.1
Young, G.S.2
-
35
-
-
79951984402
-
Phase II study of bevacizumab plus temozolomide during and after radiation therapy for patients with newly diagnosed glioblastoma multiforme
-
Lai A, Tran A et al (2011) Phase II study of bevacizumab plus temozolomide during and after radiation therapy for patients with newly diagnosed glioblastoma multiforme. J Clin Oncol 29(2): 142-148
-
(2011)
J Clin Oncol
, vol.29
, Issue.2
, pp. 142-148
-
-
Lai, A.1
Tran, A.2
-
36
-
-
51449116659
-
Feasibility of using bevacizumab with radiation therapy and temozolomide in newly diagnosed high-grade glioma
-
Narayana A, Golfinos JG et al (2008) Feasibility of using bevacizumab with radiation therapy and temozolomide in newly diagnosed high-grade glioma. Int J Rad Oncol Biol Phys 72(2): 383-389
-
(2008)
Int J Rad Oncol Biol Phys
, vol.72
, Issue.2
, pp. 383-389
-
-
Narayana, A.1
Golfinos, J.G.2
-
37
-
-
83955165997
-
Addition of bevacizumab to standard radiation therapy and daily temozolomide is associated with minimal toxicity in newly diagnosed glioblastoma multiforme
-
Vredenburgh JJ, Desjardins A et al (2012) Addition of bevacizumab to standard radiation therapy and daily temozolomide is associated with minimal toxicity in newly diagnosed glioblastoma multiforme. Int J Rad Oncol Biol Phys 82(1):58-66
-
(2012)
Int J Rad Oncol Biol Phys
, vol.82
, Issue.1
, pp. 58-66
-
-
Vredenburgh, J.J.1
Desjardins, A.2
-
38
-
-
84856806386
-
A clinical trial of bevacizumab, temozolomide, and radiation for newly diagnosed glioblastoma
-
Narayana A, Gruber D et al (2012) A clinical trial of bevacizumab, temozolomide, and radiation for newly diagnosed glioblastoma. J Neurosurgery 116(2):341-345
-
(2012)
J Neurosurgery
, vol.116
, Issue.2
, pp. 341-345
-
-
Narayana, A.1
Gruber, D.2
-
39
-
-
65249083423
-
Bevacizumab for recurrent alkylator-refractory anaplastic oligodendroglioma
-
Chamberlain MC, Johnston S (2009) Bevacizumab for recurrent alkylator-refractory anaplastic oligodendroglioma. Cancer 115(8): 1734-1743
-
(2009)
Cancer
, vol.115
, Issue.8
, pp. 1734-1743
-
-
Chamberlain, M.C.1
Johnston, S.2
-
40
-
-
75749140889
-
Bevacizumab induces regression of vestibular schwannomas in patients with neurofibromatosis type 2
-
Mautner V-F, Nguyen R et al (2010) Bevacizumab induces regression of vestibular schwannomas in patients with neurofibromatosis type 2. Neuro-Oncol 12(1):14-18
-
(2010)
Neuro-Oncol
, vol.12
, Issue.1
, pp. 14-18
-
-
Mautner, V.-F.1
Nguyen, R.2
-
41
-
-
67651173054
-
Hearing improvement after bevacizumab in patients with neurofibromatosis type 2
-
Plotkin SR, Stemmer-Rachamimov AO et al (2009) Hearing improvement after bevacizumab in patients with neurofibromatosis type 2. N Engl J Med 361(4):358-367
-
(2009)
N Engl J Med
, vol.361
, Issue.4
, pp. 358-367
-
-
Plotkin, S.R.1
Stemmer-Rachamimov, A.O.2
-
42
-
-
77958464757
-
Radiographic regression of vestibular schwannomas induced by bevacizumab treatment: Sustain under continuous drug application and rebound after drug discontinuation
-
Mautner V-F, Nguyen R et al (2010) Radiographic regression of vestibular schwannomas induced by bevacizumab treatment: sustain under continuous drug application and rebound after drug discontinuation. Ann Oncol 21(11):2294-2295
-
(2010)
Ann Oncol
, vol.21
, Issue.11
, pp. 2294-2295
-
-
Mautner, V.-F.1
Nguyen, R.2
-
43
-
-
78649457791
-
Bevacizumab-induced regression of anaplastic meningioma
-
Puchner MJA, Hans VH et al (2010) Bevacizumab-induced regression of anaplastic meningioma. Ann Oncol 21(12):2445-2446
-
(2010)
Ann Oncol
, vol.21
, Issue.12
, pp. 2445-2446
-
-
Mja, P.1
Hans, V.H.2
-
44
-
-
79953323848
-
Radiographic regression of cranial meningioma in a NF2 patient treated by bevacizumab
-
Goutagny S, Raymond E et al (2011) Radiographic regression of cranial meningioma in a NF2 patient treated by bevacizumab. Ann Oncol 22(4):990-991
-
(2011)
Ann Oncol
, vol.22
, Issue.4
, pp. 990-991
-
-
Goutagny, S.1
Raymond, E.2
-
45
-
-
70449725036
-
Safety of bevacizumab in patients with non-small-cell lung cancer and brain metastases
-
Socinski MA, Langer CJ et al (2009) Safety of bevacizumab in patients with non-small-cell lung cancer and brain metastases. J Clin Oncol 27(31):5255-5261
-
(2009)
J Clin Oncol
, vol.27
, Issue.31
, pp. 5255-5261
-
-
Socinski, M.A.1
Langer, C.J.2
-
46
-
-
67649819585
-
Bevacizumab and paclitaxel for breast cancer patients with central nervous system metastases: A case series
-
Labidi SI, Bachelot T et al (2009) Bevacizumab and paclitaxel for breast cancer patients with central nervous system metastases: a case series. Clin Breast Cancer 9(2):118-121
-
(2009)
Clin Breast Cancer
, vol.9
, Issue.2
, pp. 118-121
-
-
Labidi, S.I.1
Bachelot, T.2
-
47
-
-
57149084098
-
Bevacizumab reverses cerebral radiation necrosis
-
Wong ET, Huberman M et al (2008) Bevacizumab reverses cerebral radiation necrosis. J Clin Oncol 26(34):5649-5650
-
(2008)
J Clin Oncol
, vol.26
, Issue.34
, pp. 5649-5650
-
-
Wong, E.T.1
Huberman, M.2
-
48
-
-
67650489070
-
Initial experience with bevacizumab treatment for biopsy confirmed cerebral radiation necrosis
-
Torcuator R, Zuniga R et al (2009) Initial experience with bevacizumab treatment for biopsy confirmed cerebral radiation necrosis. J Neuro-Oncol 94(1):63-68
-
(2009)
J Neuro-Oncol
, vol.94
, Issue.1
, pp. 63-68
-
-
Torcuator, R.1
Zuniga, R.2
-
49
-
-
77954682879
-
Ramucirumab (IMC-1121B): A novel attack on angiogenesis
-
Spratlin JL, Mulder KE et al (2010) Ramucirumab (IMC-1121B): a novel attack on angiogenesis. Fut Oncol 6(7):1085-1094
-
(2010)
Fut Oncol
, vol.6
, Issue.7
, pp. 1085-1094
-
-
Spratlin, J.L.1
Mulder, K.E.2
-
50
-
-
77649213706
-
Phase i pharmacologic and biologic study of ramucirumab (IMC-1121B), a fully human immunoglobulin G1 monoclonal antibody targeting the vascular endothelial growth factor receptor-2
-
Spratlin JL, Cohen RB et al (2010) Phase I pharmacologic and biologic study of ramucirumab (IMC-1121B), a fully human immunoglobulin G1 monoclonal antibody targeting the vascular endothelial growth factor receptor-2. J Clin Oncol 28(5):780-787
-
(2010)
J Clin Oncol
, vol.28
, Issue.5
, pp. 780-787
-
-
Spratlin, J.L.1
Cohen, R.B.2
-
51
-
-
79952307327
-
Sensitivity of MRI tumor biomarkers to VEGFR inhibitor therapy in an orthotopic mouse glioma model
-
Farrar CT, Kamoun WS et al (2011) Sensitivity of MRI tumor biomarkers to VEGFR inhibitor therapy in an orthotopic mouse glioma model. PLoS One 6(3):e17228
-
(2011)
PLoS One
, vol.6
, Issue.3
-
-
Farrar, C.T.1
Kamoun, W.S.2
-
52
-
-
70349311608
-
Cediranib: Profile of a novel antiangiogenic agent in patients with glioblastoma
-
Dietrich J, Wang D et al (2009) Cediranib: profile of a novel antiangiogenic agent in patients with glioblastoma. Expert Opin Investig Drugs 18(10):1549-1557
-
(2009)
Expert Opin Investig Drugs
, vol.18
, Issue.10
, pp. 1549-1557
-
-
Dietrich, J.1
Wang, D.2
-
53
-
-
77954720781
-
Phase II study of cediranib, an oral pan-vascular endothelial growth factor receptor tyrosine kinase inhibitor, in patients with recurrent glioblastoma
-
Batchelor TT, Duda DG et al (2010) Phase II study of cediranib, an oral pan-vascular endothelial growth factor receptor tyrosine kinase inhibitor, in patients with recurrent glioblastoma. J Clin Oncol 28(17):2817-2823
-
(2010)
J Clin Oncol
, vol.28
, Issue.17
, pp. 2817-2823
-
-
Batchelor, T.T.1
Duda, D.G.2
-
54
-
-
83955164321
-
Epidermal growth factor receptor expression modulates antitumor efficacy of vandetanib or cediranib combined with radiotherapy in human glioblastoma xenografts
-
Wachsberger PR, Lawrence YR et al (2012) Epidermal growth factor receptor expression modulates antitumor efficacy of vandetanib or cediranib combined with radiotherapy in human glioblastoma xenografts. Int J Rad Oncol Biol Phys 82(1):483-491
-
(2012)
Int J Rad Oncol Biol Phys
, vol.82
, Issue.1
, pp. 483-491
-
-
Wachsberger, P.R.1
Lawrence, Y.R.2
-
55
-
-
77953611845
-
Sorafenib exerts antiglioma activity in vitro and in vivo
-
Siegelin MD, Raskett CM et al (2010) Sorafenib exerts antiglioma activity in vitro and in vivo. Neurosci Lett 478(3): 165-170
-
(2010)
Neurosci Lett
, vol.478
, Issue.3
, pp. 165-170
-
-
Siegelin, M.D.1
Raskett, C.M.2
-
56
-
-
79952541441
-
Effects of targeting the VEGF and PDGF pathways in diffuse orthotopic glioma models
-
Navis AC, Hamans BC et al (2011) Effects of targeting the VEGF and PDGF pathways in diffuse orthotopic glioma models. The J Pathol 223(5):626-634
-
(2011)
The J Pathol
, vol.223
, Issue.5
, pp. 626-634
-
-
Navis, A.C.1
Hamans, B.C.2
-
57
-
-
79959795987
-
Phase II study of sunitinib malate in patients with recurrent high-grade glioma
-
Neyns B, Sadones J et al (2011) Phase II study of sunitinib malate in patients with recurrent high-grade glioma. J Neuro-Oncol 103(3):491-501
-
(2011)
J Neuro-Oncol
, vol.103
, Issue.3
, pp. 491-501
-
-
Neyns, B.1
Sadones, J.2
-
58
-
-
77955363593
-
Concurrent radiotherapy and temozolomide followed by temozolomide and sorafenib in the first-line treatment of patients with glioblastoma multiforme
-
Hainsworth JD, Ervin T et al (2010) Concurrent radiotherapy and temozolomide followed by temozolomide and sorafenib in the first-line treatment of patients with glioblastoma multiforme. Cancer 116(15):3663-3669
-
(2010)
Cancer
, vol.116
, Issue.15
, pp. 3663-3669
-
-
Hainsworth, J.D.1
Ervin, T.2
-
59
-
-
84862909186
-
Recurrent anaplastic meningioma treated by sunitinib based on results from quantitative proteomics
-
Yoshikawa A, Nakada M et al (2012) Recurrent anaplastic meningioma treated by sunitinib based on results from quantitative proteomics. Neuropathol Appl Neurobiol 38(1):105-110
-
(2012)
Neuropathol Appl Neurobiol
, vol.38
, Issue.1
, pp. 105-110
-
-
Yoshikawa, A.1
Nakada, M.2
-
60
-
-
73349121946
-
Phase II trial of temozolomide and sorafenib in advanced melanoma patients with or without brain metastases
-
Amaravadi RK, Schuchter LM et al (2009) Phase II trial of temozolomide and sorafenib in advanced melanoma patients with or without brain metastases. Clin Cancer Res 15(24):7711-7718
-
(2009)
Clin Cancer Res
, vol.15
, Issue.24
, pp. 7711-7718
-
-
Amaravadi, R.K.1
Schuchter, L.M.2
-
61
-
-
79251478764
-
Sunitinib in metastatic renal cell carcinoma patients with brain metastases
-
Gore ME, Hariharan S et al (2011) Sunitinib in metastatic renal cell carcinoma patients with brain metastases. Cancer 117(3): 501-509
-
(2011)
Cancer
, vol.117
, Issue.3
, pp. 501-509
-
-
Gore, M.E.1
Hariharan, S.2
-
62
-
-
82955237229
-
A phase 1b trial of the combination of the antiangiogenic agent sunitinib and radiation therapy for patients with primary and metastatic central nervous system malignancies
-
Wuthrick EJ, Kamrava M et al (2011) A phase 1b trial of the combination of the antiangiogenic agent sunitinib and radiation therapy for patients with primary and metastatic central nervous system malignancies. Cancer 117(24):5548-5559
-
(2011)
Cancer
, vol.117
, Issue.24
, pp. 5548-5559
-
-
Wuthrick, E.J.1
Kamrava, M.2
-
63
-
-
73249136703
-
Cilengitide modulates attachment and viability of human glioma cells, but not sensitivity to irradiation or temozolomide in vitro
-
Maurer GD, Tritschler I et al (2009) Cilengitide modulates attachment and viability of human glioma cells, but not sensitivity to irradiation or temozolomide in vitro. Neuro-Oncol 11(6):747-756
-
(2009)
Neuro-Oncol
, vol.11
, Issue.6
, pp. 747-756
-
-
Maurer, G.D.1
Tritschler, I.2
-
64
-
-
57149108506
-
Randomized phase II study of cilengitide, an integrin-targeting arginine-glycine-aspartic acid peptide, in recurrent glioblastoma multiforme
-
Reardon DA, Fink KL et al (2008) Randomized phase II study of cilengitide, an integrin-targeting arginine-glycine-aspartic acid peptide, in recurrent glioblastoma multiforme. J Clin Oncol 26(34):5610-5617
-
(2008)
J Clin Oncol
, vol.26
, Issue.34
, pp. 5610-5617
-
-
Reardon, D.A.1
Fink, K.L.2
-
65
-
-
77954924659
-
Phase I/IIa study of cilengitide and temozolomide with concomitant radiotherapy followed by cilengitide and temozolomide maintenance therapy in patients with newly diagnosed glioblastoma
-
Stupp R, Hegi ME et al (2010) Phase I/IIa study of cilengitide and temozolomide with concomitant radiotherapy followed by cilengitide and temozolomide maintenance therapy in patients with newly diagnosed glioblastoma. J Clin Oncol 28(16):2712-2718
-
(2010)
J Clin Oncol
, vol.28
, Issue.16
, pp. 2712-2718
-
-
Stupp, R.1
Hegi, M.E.2
-
66
-
-
2942685013
-
Histone deacetylase inhibitor, FK228, induces apoptosis and suppresses cell proliferation of human glioblastoma cells in vitro and in vivo
-
DOI 10.1007/s00401-004-0841-3
-
Sawa H, Murakami H et al (2004) Histone deacetylase inhibitor, FK228, induces apoptosis and suppresses cell proliferation of human glioblastoma cells in vitro and in vivo. Acta Neuropathol 107(6):523-531 (Pubitemid 38765394)
-
(2004)
Acta Neuropathologica
, vol.107
, Issue.6
, pp. 523-531
-
-
Sawa, H.1
Murakami, H.2
Kumagai, M.3
Nakasato, M.4
Yamauchi, S.5
Matsuyama, N.6
Tamura, Y.7
Satone, A.8
Ide, W.9
Hashimoto, I.10
Kamada, H.11
-
67
-
-
79959956310
-
A phase I/II trial of the histone deacetylase inhibitor romidepsin for adults with recurrent malignant glioma: North American brain tumor consortium study 03-03
-
Iwamoto FM, Lamborn KR et al (2011) A phase I/II trial of the histone deacetylase inhibitor romidepsin for adults with recurrent malignant glioma: North American brain tumor consortium study 03-03. Neuro-Oncol 13(5):509-516
-
(2011)
Neuro-Oncol
, vol.13
, Issue.5
, pp. 509-516
-
-
Iwamoto, F.M.1
Lamborn, K.R.2
-
68
-
-
3042722188
-
Plasma and cerebrospinal fluid pharmacokinetics of depsipeptide (FR901228) in nonhuman primates
-
DOI 10.1007/s00280-004-0766-5
-
Berg SL, Stone J et al (2004) Plasma and cerebrospinal fluid pharmacokinetics of depsipeptide (FR901228) in nonhuman primates. Cancer Chemother Pharmacol 54(1):85-88 (Pubitemid 38858370)
-
(2004)
Cancer Chemotherapy and Pharmacology
, vol.54
, Issue.1
, pp. 85-88
-
-
Berg, S.L.1
Stone, J.2
Xiao, J.J.3
Chan, K.K.4
Nuchtern, J.5
Dauser, R.6
McGuffey, L.7
Thompson, P.8
Blaney, S.M.9
-
69
-
-
34548175694
-
5 integrin receptor antagonist, cilengitide (EMD 121974), in patients with advanced solid tumors
-
DOI 10.1093/annonc/mdm140
-
Hariharan S, Gustafson D et al (2007) Assessment of the biological and pharmacological effects of the amb3 and amb5 integrin receptor antagonist, cilengitide (EMD 121974), in patients with advanced solid tumors. Ann Oncol 18(8):1400-1407 (Pubitemid 47305015)
-
(2007)
Annals of Oncology
, vol.18
, Issue.8
, pp. 1400-1407
-
-
Hariharan, S.1
Gustafson, D.2
Holden, S.3
McConkey, D.4
Davis, D.5
Morrow, M.6
Basche, M.7
Gore, L.8
Zang, C.9
O'Bryant, C.L.10
Baron, A.11
Gallemann, D.12
Colevas, D.13
Eckhardt, S.G.14
-
70
-
-
33746035691
-
Cardiotoxicity of histone deacetylase inhibitor depsipeptide in patients with metastatic neuroendocrine tumors
-
DOI 10.1158/1078-0432.CCR-05-2689
-
Shah MH, Binkley P et al (2006) Cardio toxicity of histone deacetylase inhibitor depsipeptide in patients with metastatic neuroendocrine tumors. Clin Cancer Res 12(13):3997-4003 (Pubitemid 44078086)
-
(2006)
Clinical Cancer Research
, vol.12
, Issue.13
, pp. 3997-4003
-
-
Shah, M.H.1
Binkley, P.2
Chan, K.3
Xiao, J.4
Arbogast, D.5
Collamore, M.6
Farra, Y.7
Young, D.8
Grever, M.9
-
71
-
-
53149144282
-
Sunitinib-induced macrocytosis in patients with metastatic renal cell carcinoma
-
Rini BI, Choueiri TK et al (2008) Sunitinib-induced macrocytosis in patients with metastatic renal cell carcinoma. Cancer 113(6): 1309-1314
-
(2008)
Cancer
, vol.113
, Issue.6
, pp. 1309-1314
-
-
Rini, B.I.1
Choueiri, T.K.2
-
72
-
-
57449100050
-
Worsening of osteonecrosis of the jaw during treatment with sunitinib in a patient with metastatic renal cell carcinoma
-
Brunello A, Saia G et al (2009) Worsening of osteonecrosis of the jaw during treatment with sunitinib in a patient with metastatic renal cell carcinoma. Bone 44(1):173-175
-
(2009)
Bone
, vol.44
, Issue.1
, pp. 173-175
-
-
Brunello, A.1
Saia, G.2
-
73
-
-
47949099628
-
Modes of resistance to antiangiogenic therapy
-
Bergers G, Hanahan D (2008) Modes of resistance to antiangiogenic therapy. Nat Rev Cancer 8(8):592-603
-
(2008)
Nat Rev Cancer
, vol.8
, Issue.8
, pp. 592-603
-
-
Bergers, G.1
Hanahan, D.2
-
74
-
-
68049093213
-
Mediators of glioblastoma resistance and invasion during antivascular endothelial growth factor therapy
-
Lucio-Eterovic AK, Piao Y et al (2009) Mediators of glioblastoma resistance and invasion during antivascular endothelial growth factor therapy. Clin Cancer Res 15(14):4589-4599
-
(2009)
Clin Cancer Res
, vol.15
, Issue.14
, pp. 4589-4599
-
-
Lucio-Eterovic, A.K.1
Piao, Y.2
-
75
-
-
77952309402
-
Tumor invasion after treatment of glioblastoma with bevacizumab: Radiographic and pathologic correlation in humans and mice
-
de Groot JF, Fuller G et al (2010) Tumor invasion after treatment of glioblastoma with bevacizumab: radiographic and pathologic correlation in humans and mice. Neuro-Oncol 12(3):233-242
-
(2010)
Neuro-Oncol
, vol.12
, Issue.3
, pp. 233-242
-
-
De Groot, J.F.1
Fuller, G.2
-
76
-
-
70350142397
-
Patterns of relapse and prognosis after bevacizumab failure in recurrent glioblastoma
-
Iwamoto FM, Abrey LE et al (2009) Patterns of relapse and prognosis after bevacizumab failure in recurrent glioblastoma. Neurology 73(15):1200-1206
-
(2009)
Neurology
, vol.73
, Issue.15
, pp. 1200-1206
-
-
Iwamoto, F.M.1
Abrey, L.E.2
-
77
-
-
83955162975
-
Change in pattern of relapse after antiangiogenic therapy in high-grade glioma
-
Narayana A, Kunnakkat SD et al (2012) Change in pattern of relapse after antiangiogenic therapy in high-grade glioma. Int J Rad Oncol Biol Phys 82(1):77-82
-
(2012)
Int J Rad Oncol Biol Phys
, vol.82
, Issue.1
, pp. 77-82
-
-
Narayana, A.1
Kunnakkat, S.D.2
-
78
-
-
77951625266
-
Updated response assessment criteria for high-grade gliomas: Response assessment in neuro-oncology working group
-
Wen PY, Macdonald DR et al (2010) Updated response assessment criteria for high-grade gliomas: response assessment in neuro-oncology working group. J Clin Oncol 28(11):1963-1972
-
(2010)
J Clin Oncol
, vol.28
, Issue.11
, pp. 1963-1972
-
-
Wen, P.Y.1
MacDonald, D.R.2
|