-
1
-
-
0032514841
-
Extensive vasculogenesis, angiogenesis, and organogenesis precede lethality in mice lacking all alpha v integrins
-
Bader BL, Rayburn H, Crowley D, Hynes RO (1998) Extensive vasculogenesis, angiogenesis, and organogenesis precede lethality in mice lacking all alpha v integrins. Cell 95 : 507 519.
-
(1998)
Cell
, vol.95
, pp. 507-519
-
-
Bader, B.L.1
Rayburn, H.2
Crowley, D.3
Hynes, R.O.4
-
2
-
-
33846596083
-
Molecular imaging with new PET tracers
-
Beer AJ, Schwaiger M (2007) Molecular imaging with new PET tracers. Radiologe 47 : 8 17.
-
(2007)
Radiologe
, vol.47
, pp. 8-17
-
-
Beer, A.J.1
Schwaiger, M.2
-
3
-
-
25444503494
-
Biodistribution and pharmacokinetics of the alphavbeta3-selective tracer 18F-galacto-RGD in cancer patients
-
Beer AJ, Haubner R, Goebel M, Luderschmidt S, Spilker ME, Wester HJ et al (2005) Biodistribution and pharmacokinetics of the alphavbeta3-selective tracer 18F-galacto-RGD in cancer patients. J Nucl Med 46 : 1333 1341.
-
(2005)
J Nucl Med
, vol.46
, pp. 1333-1341
-
-
Beer, A.J.1
Haubner, R.2
Goebel, M.3
Luderschmidt, S.4
Spilker, M.E.5
Wester, H.J.6
Al, E.7
-
4
-
-
33746032220
-
Positron emission tomography using [18F] Galacto-RGD identifies the level of integrin alpha(v)beta3 expression in man
-
Beer AJ, Haubner R, Sarbia M, Goebel M, Luderschmidt S, Grosu AL et al (2006) Positron emission tomography using [18F] Galacto-RGD identifies the level of integrin alpha(v)beta3 expression in man. Clin Cancer Res 12 : 3942 3949.
-
(2006)
Clin Cancer Res
, vol.12
, pp. 3942-3949
-
-
Beer, A.J.1
Haubner, R.2
Sarbia, M.3
Goebel, M.4
Luderschmidt, S.5
Grosu, A.L.6
Al, E.7
-
5
-
-
17844367105
-
Alpha(v)beta3 and alpha(v)beta5 integrin expression in glioma periphery
-
Bello L, Francolini M, Marthyn P, Zhang J, Carroll RS, Nikas DC et al (2001) Alpha(v)beta3 and alpha(v)beta5 integrin expression in glioma periphery. Neurosurgery 49 : 380 389.
-
(2001)
Neurosurgery
, vol.49
, pp. 380-389
-
-
Bello, L.1
Francolini, M.2
Marthyn, P.3
Zhang, J.4
Carroll, R.S.5
Nikas, D.C.6
Al, E.7
-
6
-
-
0035893737
-
Simultaneous inhibition of glioma angiogenesis, cell proliferation, and invasion by a naturally occurring fragment of human metalloproteinase-2
-
Bello L, Lucini V, Carrabba G, Giussani C, Machluf M, Pluderi M et al (2001) Simultaneous inhibition of glioma angiogenesis, cell proliferation, and invasion by a naturally occurring fragment of human metalloproteinase-2. Cancer Res 61 : 8730 8736.
-
(2001)
Cancer Res
, vol.61
, pp. 8730-8736
-
-
Bello, L.1
Lucini, V.2
Carrabba, G.3
Giussani, C.4
MacHluf, M.5
Pluderi, M.6
Al, E.7
-
7
-
-
0037209122
-
IS20I, a specific alphavbeta3 integrin inhibitor, reduces glioma growth in vivo
-
Bello L, Lucini V, Giussani C, Carrabba G, Pluderi M, Scaglione F et al (2003) IS20I, a specific alphavbeta3 integrin inhibitor, reduces glioma growth in vivo. Neurosurgery 52 : 177 185.
-
(2003)
Neurosurgery
, vol.52
, pp. 177-185
-
-
Bello, L.1
Lucini, V.2
Giussani, C.3
Carrabba, G.4
Pluderi, M.5
Scaglione, F.6
Al, E.7
-
8
-
-
0035925174
-
Identification of a novel class of small-molecule antiangiogenic agents through the screening of combinatorial libraries which function by inhibiting the binding and localization of proteinase MMP2 to integrin alpha(V)beta(3)
-
Boger DL, Goldberg J, Silletti S, Kessler T, Cheresh DA (2001) Identification of a novel class of small-molecule antiangiogenic agents through the screening of combinatorial libraries which function by inhibiting the binding and localization of proteinase MMP2 to integrin alpha(V)beta(3). J Am Chem Soc 123 : 1280 1288.
-
(2001)
J Am Chem Soc
, vol.123
, pp. 1280-1288
-
-
Boger, D.L.1
Goldberg, J.2
Silletti, S.3
Kessler, T.4
Cheresh, D.A.5
-
9
-
-
0028670833
-
Integrin alpha v beta 3 antagonists promote tumor regression by inducing apoptosis of angiogenic blood vessels
-
Brooks PC, Montgomery AM, Rosenfeld M, Reisfeld RA, Hu T, Klier G et al (1994) Integrin alpha v beta 3 antagonists promote tumor regression by inducing apoptosis of angiogenic blood vessels. Cell 79 : 1157 1164.
-
(1994)
Cell
, vol.79
, pp. 1157-1164
-
-
Brooks, P.C.1
Montgomery, A.M.2
Rosenfeld, M.3
Reisfeld, R.A.4
Hu, T.5
Klier, G.6
Al, E.7
-
10
-
-
0028972105
-
Antiintegrin alpha v beta 3 blocks human breast cancer growth and angiogenesis in human skin
-
Brooks PC, Stromblad S, Klemke R, Visscher D, Sarkar FH, Cheresh DA (1995) Antiintegrin alpha v beta 3 blocks human breast cancer growth and angiogenesis in human skin. J Clin Invest 96 : 1815 1822.
-
(1995)
J Clin Invest
, vol.96
, pp. 1815-1822
-
-
Brooks, P.C.1
Stromblad, S.2
Klemke, R.3
Visscher, D.4
Sarkar, F.H.5
Cheresh, D.A.6
-
11
-
-
15844420283
-
Localization of matrix metalloproteinase MMP-2 to the surface of invasive cells by interaction with integrin alpha v beta 3
-
Brooks PC, Stromblad S, Sanders LC, von Schalscha TL, Aimes RT, Stetler-Stevenson WG et al (1996) Localization of matrix metalloproteinase MMP-2 to the surface of invasive cells by interaction with integrin alpha v beta 3. Cell 85 : 683 693.
-
(1996)
Cell
, vol.85
, pp. 683-693
-
-
Brooks, P.C.1
Stromblad, S.2
Sanders, L.C.3
Von Schalscha, T.L.4
Aimes, R.T.5
Stetler-Stevenson, W.G.6
Al, E.7
-
12
-
-
0023612102
-
Biosynthetic and functional properties of an Arg-Gly-Asp-directed receptor involved in human melanoma cell attachment to vitronectin, fibrinogen, and von Willebrand factor
-
Cheresh DA, Spiro RC (1987) Biosynthetic and functional properties of an Arg-Gly-Asp-directed receptor involved in human melanoma cell attachment to vitronectin, fibrinogen, and von Willebrand factor. J Biol Chem 262 : 17703 17711.
-
(1987)
J Biol Chem
, vol.262
, pp. 17703-17711
-
-
Cheresh, D.A.1
Spiro, R.C.2
-
13
-
-
0036130826
-
Integrin-mediated death: An explanation of the integrin-knockout phenotype?
-
Cheresh DA, Stupack DG (2002) Integrin-mediated death: an explanation of the integrin-knockout phenotype? Nat Med 8 : 193 194.
-
(2002)
Nat Med
, vol.8
, pp. 193-194
-
-
Cheresh, D.A.1
Stupack, D.G.2
-
14
-
-
9144232309
-
Molecular mechanisms of glioma cell migration and invasion
-
Demuth T, Berens ME (2004) Molecular mechanisms of glioma cell migration and invasion. J Neurooncol 70 : 217 228.
-
(2004)
J Neurooncol
, vol.70
, pp. 217-228
-
-
Demuth, T.1
Berens, M.E.2
-
15
-
-
0029610677
-
Definition of two angiogenic pathways by distinct alpha v integrins
-
Friedlander M, Brooks PC, Shaffer RW, Kincaid CM, Varner JA, Cheresh DA (1995) Definition of two angiogenic pathways by distinct alpha v integrins. Science 270 : 1500 1502.
-
(1995)
Science
, vol.270
, pp. 1500-1502
-
-
Friedlander, M.1
Brooks, P.C.2
Shaffer, R.W.3
Kincaid, C.M.4
Varner, J.A.5
Cheresh, D.A.6
-
16
-
-
0029846478
-
Expression of integrin alpha v beta 3 in small blood vessels of glioblastoma tumors
-
Gladson CL (1996) Expression of integrin alpha v beta 3 in small blood vessels of glioblastoma tumors. J Neuropathol Exp Neurol 55 : 1143 1149.
-
(1996)
J Neuropathol Exp Neurol
, vol.55
, pp. 1143-1149
-
-
Gladson, C.L.1
-
17
-
-
0026334978
-
Glioblastoma expression of vitronectin and the alpha v beta 3 integrin. Adhesion mechanism for transformed glial cells
-
Gladson CL, Cheresh DA (1991) Glioblastoma expression of vitronectin and the alpha v beta 3 integrin. Adhesion mechanism for transformed glial cells. J Clin Invest 88 : 1924 1932.
-
(1991)
J Clin Invest
, vol.88
, pp. 1924-1932
-
-
Gladson, C.L.1
Cheresh, D.A.2
-
18
-
-
0028940958
-
Cerebral microenvironment influences expression of the vitronectin gene in astrocytic tumors
-
Gladson CL, Wilcox JN, Sanders L, Gillespie GY, Cheresh DA (1995) Cerebral microenvironment influences expression of the vitronectin gene in astrocytic tumors. J Cell Sci 108 : 947 956.
-
(1995)
J Cell Sci
, vol.108
, pp. 947-956
-
-
Gladson, C.L.1
Wilcox, J.N.2
Sanders, L.3
Gillespie, G.Y.4
Cheresh, D.A.5
-
19
-
-
0032587186
-
Radiolabeled alpha(v)beta3 integrin antagonists: A new class of tracers for tumor targeting
-
Haubner R, Wester HJ, Reuning U, Senekowitsch-Schmidtke R, Diefenbach B, Kessler H et al (1999) Radiolabeled alpha(v)beta3 integrin antagonists: a new class of tracers for tumor targeting. J Nucl Med 40 : 1061 1071.
-
(1999)
J Nucl Med
, vol.40
, pp. 1061-1071
-
-
Haubner, R.1
Wester, H.J.2
Reuning, U.3
Senekowitsch-Schmidtke, R.4
Diefenbach, B.5
Kessler, H.6
Al, E.7
-
20
-
-
18244376347
-
Noninvasive visualization of the activated alphavbeta3 integrin in cancer patients by positron emission tomography and [18F]Galacto-RGD
-
Haubner R, Weber WA, Beer AJ, Vabuliene E, Reim D, Sarbia M et al (2005) Noninvasive visualization of the activated alphavbeta3 integrin in cancer patients by positron emission tomography and [18F]Galacto-RGD. PLoS Med 2 : e70.
-
(2005)
PLoS Med
, vol.2
-
-
Haubner, R.1
Weber, W.A.2
Beer, A.J.3
Vabuliene, E.4
Reim, D.5
Sarbia, M.6
Al, E.7
-
22
-
-
0032590042
-
Beta3-integrin-deficient mice are a model for Glanzmann thrombasthenia showing placental defects and reduced survival
-
Hodivala-Dilke KM, McHugh KP, Tsakiris DA, Rayburn H, Crowley D, Ullman-Cullere M et al (1999) Beta3-integrin-deficient mice are a model for Glanzmann thrombasthenia showing placental defects and reduced survival. J Clin Invest 103 : 229 238.
-
(1999)
J Clin Invest
, vol.103
, pp. 229-238
-
-
Hodivala-Dilke, K.M.1
McHugh, K.P.2
Tsakiris, D.A.3
Rayburn, H.4
Crowley, D.5
Ullman-Cullere, M.6
Al, E.7
-
23
-
-
0026770377
-
Integrins: Versatility, modulation, and signaling in cell adhesion
-
Hynes RO (1992) Integrins: versatility, modulation, and signaling in cell adhesion. Cell 69 : 11 25.
-
(1992)
Cell
, vol.69
, pp. 11-25
-
-
Hynes, R.O.1
-
24
-
-
0036734093
-
A reevaluation of integrins as regulators of angiogenesis
-
Hynes RO (2002) A reevaluation of integrins as regulators of angiogenesis. Nat Med 8 : 918 921.
-
(2002)
Nat Med
, vol.8
, pp. 918-921
-
-
Hynes, R.O.1
-
26
-
-
0036192918
-
The WHO classification of tumors of the nervous system
-
Kleihues P, Louis DN, Scheithauer BW, Rorke LB, Reifenberger G, Burger PC et al (2002) The WHO classification of tumors of the nervous system. J Neuropathol Exp Neurol 61 : 215 225.
-
(2002)
J Neuropathol Exp Neurol
, vol.61
, pp. 215-225
-
-
Kleihues, P.1
Louis, D.N.2
Scheithauer, B.W.3
Rorke, L.B.4
Reifenberger, G.5
Burger, P.C.6
Al, E.7
-
27
-
-
33646064702
-
A method to perform Western blots of microscopic areas of histological sections
-
Krebs B, Kohlmannsperger V, Nolting S, Schmalzbauer R, Kretzschmar HA (2006) A method to perform Western blots of microscopic areas of histological sections. J Histochem Cytochem 54 : 559 565.
-
(2006)
J Histochem Cytochem
, vol.54
, pp. 559-565
-
-
Krebs, B.1
Kohlmannsperger, V.2
Nolting, S.3
Schmalzbauer, R.4
Kretzschmar, H.A.5
-
28
-
-
0020794694
-
Rapid and sensitive colorimetric method for visualizing biotin-labeled DNA probes hybridized to DNA or RNA immobilized on nitrocellulose: Bio-blots
-
Leary JJ, Brigati DJ, Ward DC (1983) Rapid and sensitive colorimetric method for visualizing biotin-labeled DNA probes hybridized to DNA or RNA immobilized on nitrocellulose: bio-blots. Proc Natl Acad Sci USA 80 : 4045 4049.
-
(1983)
Proc Natl Acad Sci USA
, vol.80
, pp. 4045-4049
-
-
Leary, J.J.1
Brigati, D.J.2
Ward, D.C.3
-
29
-
-
0035149747
-
Preferential susceptibility of brain tumors to the antiangiogenic effects of an alpha(v) integrin antagonist
-
Macdonald TJ, Taga T, Shimada H, Tabrizi P, Zlokovic BV, Cheresh DA et al (2001) Preferential susceptibility of brain tumors to the antiangiogenic effects of an alpha(v) integrin antagonist. Neurosurgery 48 : 151 157.
-
(2001)
Neurosurgery
, vol.48
, pp. 151-157
-
-
MacDonald, T.J.1
Taga, T.2
Shimada, H.3
Tabrizi, P.4
Zlokovic, B.V.5
Cheresh, D.A.6
Al, E.7
-
30
-
-
3242666000
-
Expression of matrix metalloproteinases and their inhibitors in medulloblastomas and their prognostic relevance
-
Ozen O, Krebs B, Hemmerlein B, Pekrun A, Kretzschmar H, Herms J (2004) Expression of matrix metalloproteinases and their inhibitors in medulloblastomas and their prognostic relevance. Clin Cancer Res 10 : 4746 4753.
-
(2004)
Clin Cancer Res
, vol.10
, pp. 4746-4753
-
-
Ozen, O.1
Krebs, B.2
Hemmerlein, B.3
Pekrun, A.4
Kretzschmar, H.5
Herms, J.6
-
31
-
-
0029040579
-
Interactions of glioma cells and extracellular matrix
-
Paulus W, Tonn JC (1995) Interactions of glioma cells and extracellular matrix. J Neurooncol 24 : 87 91.
-
(1995)
J Neurooncol
, vol.24
, pp. 87-91
-
-
Paulus, W.1
Tonn, J.C.2
-
32
-
-
0027753101
-
Characterization of integrin receptors in normal and neoplastic human brain
-
Paulus W, Baur I, Schuppan D, Roggendorf W (1993) Characterization of integrin receptors in normal and neoplastic human brain. Am J Pathol 143 : 154 163.
-
(1993)
Am J Pathol
, vol.143
, pp. 154-163
-
-
Paulus, W.1
Baur, I.2
Schuppan, D.3
Roggendorf, W.4
-
33
-
-
33746233383
-
Synapse formation and function is modulated by the amyloid precursor protein
-
Priller C, Bauer T, Mitteregger G, Krebs B, Kretzschmar HA, Herms J (2006) Synapse formation and function is modulated by the amyloid precursor protein. J Neurosci 26 : 7212 7221.
-
(2006)
J Neurosci
, vol.26
, pp. 7212-7221
-
-
Priller, C.1
Bauer, T.2
Mitteregger, G.3
Krebs, B.4
Kretzschmar, H.A.5
Herms, J.6
-
34
-
-
44649188707
-
Pathology and classification of tumors of the nervous system
-
In: J.C. Tonn, M. Westphal, J.T. Rutka, G. Sae (. eds), pp. Springer: Berlin Heidelberg New York.
-
Reifenberger G, Blümcke I, Pietsch T, Paulus W (2006) Pathology and classification of tumors of the nervous system. In : Neuro-Oncology of CNS-Tumors, JC Tonn, M Westphal, JT Rutka, G Sae (eds), pp. 3 72. Springer : Berlin Heidelberg New York.
-
(2006)
Neuro-Oncology of CNS-Tumors
, pp. 3-72
-
-
Reifenberger, G.1
Blümcke, I.2
Pietsch, T.3
Paulus, W.4
-
35
-
-
0036152857
-
Enhanced pathological angiogenesis in mice lacking beta3 integrin or beta3 and beta5 integrins
-
Reynolds LE, Wyder L, Lively JC, Taverna D, Robinson SD, Huang X et al (2002) Enhanced pathological angiogenesis in mice lacking beta3 integrin or beta3 and beta5 integrins. Nat Med 8 : 27 34.
-
(2002)
Nat Med
, vol.8
, pp. 27-34
-
-
Reynolds, L.E.1
Wyder, L.2
Lively, J.C.3
Taverna, D.4
Robinson, S.D.5
Huang, X.6
Al, E.7
-
37
-
-
0035793037
-
Disruption of matrix metalloproteinase 2 binding to integrin alpha vbeta 3 by an organic molecule inhibits angiogenesis and tumor growth in vivo
-
Silletti S, Kessler T, Goldberg J, Boger DL, Cheresh DA (2001) Disruption of matrix metalloproteinase 2 binding to integrin alpha vbeta 3 by an organic molecule inhibits angiogenesis and tumor growth in vivo. Proc Natl Acad Sci USA 98 : 119 124.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 119-124
-
-
Silletti, S.1
Kessler, T.2
Goldberg, J.3
Boger, D.L.4
Cheresh, D.A.5
-
38
-
-
0037051697
-
Alpha v-Integrin antagonist EMD
-
121974 induces apoptosis in brain tumor cells growing on vitronectin and tenascin.
-
Taga T, Suzuki A, Gonzalez-Gomez I, Gilles FH, Stins M, Shimada H et al (2002) Alpha v-Integrin antagonist EMD 121974 induces apoptosis in brain tumor cells growing on vitronectin and tenascin. Int J Cancer 98 : 690 697.
-
(2002)
Int J Cancer
, vol.98
, pp. 690-697
-
-
Taga, T.1
Suzuki, A.2
Gonzalez-Gomez, I.3
Gilles, F.H.4
Stins, M.5
Shimada, H.6
Al, E.7
-
39
-
-
0034115558
-
Tissue factor, osteopontin, alphavbeta3 integrin expression in microvasculature of gliomas associated with vascular endothelial growth factor expression
-
Takano S, Tsuboi K, Tomono Y, Mitsui Y, Nose T (2000) Tissue factor, osteopontin, alphavbeta3 integrin expression in microvasculature of gliomas associated with vascular endothelial growth factor expression. Br J Cancer 82 : 1967 1973.
-
(2000)
Br J Cancer
, vol.82
, pp. 1967-1973
-
-
Takano, S.1
Tsuboi, K.2
Tomono, Y.3
Mitsui, Y.4
Nose, T.5
-
40
-
-
27944456442
-
The role of the extracellular matrix in angiogenesis in malignant glioma tumors
-
Wang D, Anderson JC, Gladson CL (2005) The role of the extracellular matrix in angiogenesis in malignant glioma tumors. Brain Pathol 15 : 318 326.
-
(2005)
Brain Pathol
, vol.15
, pp. 318-326
-
-
Wang, D.1
Anderson, J.C.2
Gladson, C.L.3
-
41
-
-
0035850669
-
Crystal structure of the extracellular segment of integrin alpha Vbeta3
-
Xiong JP, Stehle T, Diefenbach B, Zhang R, Dunker R, Scott DL et al (2001) Crystal structure of the extracellular segment of integrin alpha Vbeta3. Science 294 : 339 345.
-
(2001)
Science
, vol.294
, pp. 339-345
-
-
Xiong, J.P.1
Stehle, T.2
Diefenbach, B.3
Zhang, R.4
Dunker, R.5
Scott, D.L.6
Al, E.7
|