HDAC inhibitor, scriptaid, induces glioma cell apoptosis through JNK activation and inhibits telomerase activity

Journal of Cellular and Molecular Medicine

Volumn 14, Issue 8, 2010, Pages 2151-2161

  Sharma, Vivek ^a   Koul, Nitin ^a   Joseph, Christy ^a   Dixit, Deobrat ^a   Ghosh, Sadashib ^a   Sen, Ellora ^a  

^a NATIONAL BRAIN RESEARCH CENTRE   (India)

Author keywords

Glioblastoma; HDAC inhibitors; JNK; Ras; Scriptaid; Telomerase

Indexed keywords

6 (1,3 DIOXO 1H,3H BENZO[DE]ISOQUINOLIN 2 YL) N HYDROXYHEXANAMIDE; ANTHRA(1,9 CD)PYRAZOL 6(2H) ONE; ANTHRA(1,9-CD)PYRAZOL-6(2H)-ONE; ANTHRACENE DERIVATIVE; CELL CYCLE PROTEIN; HISTONE; HISTONE DEACETYLASE; HISTONE DEACETYLASE INHIBITOR; HYDROXYLAMINE; QUINOLINE DERIVATIVE; RAS PROTEIN; STRESS ACTIVATED PROTEIN KINASE; TELOMERASE;

ACETYLATION; APOPTOSIS; ARTICLE; CELL CYCLE; CELL PROLIFERATION; DNA DAMAGE; DOSE RESPONSE; DRUG ANTAGONISM; DRUG EFFECT; ENZYME ACTIVATION; ENZYME LINKED IMMUNOSORBENT ASSAY; GENETICS; GLIOMA; HUMAN; METABOLISM; METHODOLOGY; PATHOLOGY; POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TUMOR CELL LINE; WESTERN BLOTTING;

ACETYLATION; ANTHRACENES; APOPTOSIS; BLOTTING, WESTERN; CELL CYCLE; CELL CYCLE PROTEINS; CELL LINE, TUMOR; CELL PROLIFERATION; DNA DAMAGE; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME ACTIVATION; ENZYME-LINKED IMMUNOSORBENT ASSAY; GLIOMA; HISTONE DEACETYLASE INHIBITORS; HISTONE DEACETYLASES; HISTONES; HUMANS; HYDROXYLAMINES; JNK MITOGEN-ACTIVATED PROTEIN KINASES; POLYMERASE CHAIN REACTION; QUINOLINES; RAS PROTEINS; SIGNAL TRANSDUCTION; TELOMERASE;

EID: 77957120976     PISSN: 15821838     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1582-4934.2009.00844.x     Document Type: Article

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