SCOPUS 정보 검색 플랫폼

Bioorganic and Medicinal Chemistry Letters

Volumn 22, Issue 19, 2012, Pages 6256-6260

Antitrypanosomal and cysteine protease inhibitory activities of alkyldiamine cryptolepine derivatives

(6) Lavrado, João a MacKey, Zachary b,c Hansell, Elizabeth b McKerrow, James H b Paulo, Alexandra a Moreira, Rui a

a RESEARCH INSTITUTE FOR MEDICINES IMED ULISBOA (Portugal)

b UNIVERSITY OF CALIFORNIA (United States)

c VIRGINIA POLYTECHNIC INSTITUTE AND STATE UNIVERSITY (United States)

Author keywords

Cruzain; Cryptolepine; Indoloquinolines; Rhodesain; Trypanosoma

Indexed keywords

ALKYLDIAMINE CRYPTOLEPINE DERIVATIVE; ANTITRYPANOSOMAL AGENT; CRUZIPAIN; CRYPTOLEPINE DERIVATIVE; CYSTEINE PROTEINASE INHIBITOR; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; IC 50; NONHUMAN; PARASITE; TRYPANOSOMA BRUCEI;

ANTIPROTOZOAL AGENTS; CATALYTIC DOMAIN; CYSTEINE PROTEASES; CYSTEINE PROTEINASE INHIBITORS; DIAMINES; DOSE-RESPONSE RELATIONSHIP, DRUG; INDOLE ALKALOIDS; MODELS, MOLECULAR; MOLECULAR STRUCTURE; PARASITIC SENSITIVITY TESTS; QUINOLINES; STRUCTURE-ACTIVITY RELATIONSHIP; TRYPANOSOMA BRUCEI BRUCEI;

TRYPANOSOMA; TRYPANOSOMA BRUCEI BRUCEI;

EID: 84866368999 PISSN: 0960894X EISSN: 14643405 Source Type: Journal
DOI: 10.1016/j.bmcl.2012.07.104 Document Type: Article

Times cited : (19)

References (25)

1
- 35548987998
- F. Chappuis, S. Sundar, A. Hailu, H. Ghalib, S. Rijal, R.W. Peeling, J. Alvar, and M. Boelaert Nat. Rev. Microbiol. 5 2007 873
- (2007) Nat. Rev. Microbiol. , vol.5 , pp. 873
- Chappuis, F.¹ Sundar, S.² Hailu, A.³ Ghalib, H.⁴ Rijal, S.⁵ Peeling, R.W.⁶ Alvar, J.⁷ Boelaert, M.⁸

2
- 84873985343
- WHO, September
- WHO. http://www.who.int/topics/chagas-disease/en/, September 2011.
- (2011)

3
- 84873983184
- WHO, September
- WHO. http://www.who.int/mediacentre/factsheets/fs259/en/, September 2011.
- (2011)

4
- 65549137912
- D.R.M. Moreira, A.C.L. Leite, R.R. dos Santos, and M.B.P. Soares Curr. Drug Targets 10 2009 212
- (2009) Curr. Drug Targets , vol.10 , pp. 212
- Moreira, D.R.M.¹ Leite, A.C.L.² Dos Santos, R.R.³ Soares, M.B.P.⁴

5
- 26844461073
- S.L. Croft, M.P. Barrett, and J.A. Urbina Trends in Parasitol. 21 2005 508
- (2005) Trends in Parasitol. , vol.21 , pp. 508
- Croft, S.L.¹ Barrett, M.P.² Urbina, J.A.³

6
- 79851504683
- J. Lavrado, G.G. Cabal, M. Prudencio, M.M. Mota, J. Gut, P.J. Rosenthal, C. Diaz, R.C. Guedes, D.J. Dos Santos, E. Bichenkova, K.T. Douglas, R. Moreira, and A. Paulo J. Med. Chem. 54 2011 734
- (2011) J. Med. Chem. , vol.54 , pp. 734
- Lavrado, J.¹ Cabal, G.G.² Prudencio, M.³ Mota, M.M.⁴ Gut, J.⁵ Rosenthal, P.J.⁶ Diaz, C.⁷ Guedes, R.C.⁸ Dos Santos, D.J.⁹ Bichenkova, E.¹⁰ Douglas, K.T.¹¹ Moreira, R.¹² Paulo, A.¹³

7
- 77955637981
- J. Lavrado, R. Moreira, and A. Paulo Curr. Med. Chem. 17 2010 2348
- (2010) Curr. Med. Chem. , vol.17 , pp. 2348
- Lavrado, J.¹ Moreira, R.² Paulo, A.³

8
- 0033564239
- L. Dassonneville, K. Bonjean, M.C. De Pauw-Gillet, P. Colson, C. Houssier, J. Quetin-Leclercq, L. Angenot, and C. Bailly Biochemistry 38 1999 7719
- (1999) Biochemistry , vol.38 , pp. 7719
- Dassonneville, L.¹ Bonjean, K.² De Pauw-Gillet, M.C.³ Colson, P.⁴ Houssier, C.⁵ Quetin-Leclercq, J.⁶ Angenot, L.⁷ Bailly, C.⁸

9
- 0036906337
- C. Ansah, and N.J. Gooderham Toxicol. Sci. 70 2002 245
- (2002) Toxicol. Sci. , vol.70 , pp. 245
- Ansah, C.¹ Gooderham, N.J.²

10
- 0036142318
- J.N. Lisgarten, M. Coll, J. Portugal, C.W. Wright, and J. Aymami Nat. Struct. Biol. 9 2002 57
- (2002) Nat. Struct. Biol. , vol.9 , pp. 57
- Lisgarten, J.N.¹ Coll, M.² Portugal, J.³ Wright, C.W.⁴ Aymami, J.⁵

11
- 4644357065
- I.M. Aparicio, J. Scharfstein, and A.P.C.A. Lima Infect. Immun. 72 2004 5892
- (2004) Infect. Immun. , vol.72 , pp. 5892
- Aparicio, I.M.¹ Scharfstein, J.² Lima, A.P.C.A.³

12
- 0034767886
- C.R. Caffrey, E. Hansell, K.D. Lucas, L.S. Brinen, A.A. Hernandez, J.N. Cheng, S.L. Gwaltney, W.R. Roush, Y.D. Stierhof, M. Bogyo, D. Steverding, and J.H. McKerrow Mol. Biochem. Parasitol. 118 2001 61
- (2001) Mol. Biochem. Parasitol. , vol.118 , pp. 61
- Caffrey, C.R.¹ Hansell, E.² Lucas, K.D.³ Brinen, L.S.⁴ Hernandez, A.A.⁵ Cheng, J.N.⁶ Gwaltney, S.L.⁷ Roush, W.R.⁸ Stierhof, Y.D.⁹ Bogyo, M.¹⁰ Steverding, D.¹¹ McKerrow, J.H.¹²

13
- 33646373912
- O.V. Nikolskaia, Y.V. Kim, O. Kovbasnjuk, K.J. Kim, and D.J. Grab Int. J. Parasitol. 36 2006 513
- (2006) Int. J. Parasitol. , vol.36 , pp. 513
- Nikolskaia, O.V.¹ Kim, Y.V.² Kovbasnjuk, O.³ Kim, K.J.⁴ Grab, D.J.⁵

14
- 0033058811
- J.H. McKerrow, J.C. Engel, and C.R. Caffrey Bioorg. Med. Chem. 7 1999 639
- (1999) Bioorg. Med. Chem. , vol.7 , pp. 639
- McKerrow, J.H.¹ Engel, J.C.² Caffrey, C.R.³

15
- 39149083105
- J.P. Mallari, A.A. Shelat, T. Obrien, C.R. Caffrey, A. Kosinski, M. Connelly, M. Harbut, D. Greenbaum, J.H. McKerrow, and R.K. Guy J. Med. Chem. 51 2008 545
- (2008) J. Med. Chem. , vol.51 , pp. 545
- Mallari, J.P.¹ Shelat, A.A.² Obrien, T.³ Caffrey, C.R.⁴ Kosinski, A.⁵ Connelly, M.⁶ Harbut, M.⁷ Greenbaum, D.⁸ McKerrow, J.H.⁹ Guy, R.K.¹⁰

16
- 77956172941
- I.D. Kerr, P. Wu, R. Marion-Tsukamaki, Z.B. Mackey, and L.S. Brinen Plos Negl. Trop. Dis. 4 2010 e701
- (2010) Plos Negl. Trop. Dis. , vol.4 , pp. 701
- Kerr, I.D.¹ Wu, P.² Marion-Tsukamaki, R.³ MacKey, Z.B.⁴ Brinen, L.S.⁵

17
- 84866348334
- M.D. Carreiras, J. Marco-Contelles, Research Signpost Kerala, India
- J. Lavrado, R. Moreira, and A. Paulo M.D. Carreiras, J. Marco-Contelles, Heterocyclic Targets in Advanced Organic Synthesis 2011 Research Signpost Kerala, India 109
- (2011) Heterocyclic Targets in Advanced Organic Synthesis , pp. 109
- Lavrado, J.¹ Moreira, R.² Paulo, A.³

18
- 38949089316
- J. Lavrado, A. Paulo, J. Gut, P.J. Rosenthal, and R. Moreira Bioorg. Med. Chem. Lett. 18 2008 1378
- (2008) Bioorg. Med. Chem. Lett. , vol.18 , pp. 1378
- Lavrado, J.¹ Paulo, A.² Gut, J.³ Rosenthal, P.J.⁴ Moreira, R.⁵

19
- 33745199861
- Z.B. Mackey, A.M. Baca, J.P. Mallari, B. Apsel, A. Shelat, E.J. Hansell, P.K. Chiang, B. Wolff, K.R. Guy, J. Williams, and J.H. McKerrow Chem. Biol. Drug Des. 67 2006 355
- (2006) Chem. Biol. Drug Des. , vol.67 , pp. 355
- MacKey, Z.B.¹ Baca, A.M.² Mallari, J.P.³ Apsel, B.⁴ Shelat, A.⁵ Hansell, E.J.⁶ Chiang, P.K.⁷ Wolff, B.⁸ Guy, K.R.⁹ Williams, J.¹⁰ McKerrow, J.H.¹¹

20
- 79957989066
- K.K. Ang, J. Ratnam, J. Gut, J. Legac, E. Hansell, Z.B. Mackey, K.M. Skrzypczynska, A. Debnath, J.C. Engel, P.J. Rosenthal, J.H. McKerrow, M.R. Arkin, and A.R. Renslo PLoS Negl. Trop. Dis. 5 2011 e1023
- (2011) PLoS Negl. Trop. Dis. , vol.5 , pp. 1023
- Ang, K.K.¹ Ratnam, J.² Gut, J.³ Legac, J.⁴ Hansell, E.⁵ MacKey, Z.B.⁶ Skrzypczynska, K.M.⁷ Debnath, A.⁸ Engel, J.C.⁹ Rosenthal, P.J.¹⁰ McKerrow, J.H.¹¹ Arkin, M.R.¹² Renslo, A.R.¹³

21
- 74849121149
- B.T. Mott, R.S. Ferreira, A. Simeonov, A. Jadhav, K.K.H. Ang, W. Leister, M. Shen, J.T. Silveira, P.S. Doyle, M.R. Arkin, J.H. McKerrow, J. Inglese, C.P. Austin, C.J. Thomas, B.K. Shoichet, and D.J. Maloney J. Med. Chem. 53 2010 52
- (2010) J. Med. Chem. , vol.53 , pp. 52
- Mott, B.T.¹ Ferreira, R.S.² Simeonov, A.³ Jadhav, A.⁴ Ang, K.K.H.⁵ Leister, W.⁶ Shen, M.⁷ Silveira, J.T.⁸ Doyle, P.S.⁹ Arkin, M.R.¹⁰ McKerrow, J.H.¹¹ Inglese, J.¹² Austin, C.P.¹³ Thomas, C.J.¹⁴ Shoichet, B.K.¹⁵ Maloney, D.J.¹⁶

22
- 0041919542
- M.L. Verdonk, J.C. Cole, M.J. Hartshorn, C.W. Murray, and R.D. Taylor Proteins-structure function and genetics 52 2003 609
- (2003) Proteins-structure Function and Genetics , vol.52 , pp. 609
- Verdonk, M.L.¹ Cole, J.C.² Hartshorn, M.J.³ Murray, C.W.⁴ Taylor, R.D.⁵

23
- 70350002086
- I.D. Kerr, J.H. Lee, C.J. Farady, R. Marion, M. Rickert, M. Sajid, K.C. Pandey, C.R. Caffrey, J. Legac, E. Hansell, J.H. McKerrow, C.S. Craik, P.J. Rosenthal, and L.S. Brinen J. Biol. Chem. 284 2009 25697
- (2009) J. Biol. Chem. , vol.284 , pp. 25697
- Kerr, I.D.¹ Lee, J.H.² Farady, C.J.³ Marion, R.⁴ Rickert, M.⁵ Sajid, M.⁶ Pandey, K.C.⁷ Caffrey, C.R.⁸ Legac, J.⁹ Hansell, E.¹⁰ McKerrow, J.H.¹¹ Craik, C.S.¹² Rosenthal, P.J.¹³ Brinen, L.S.¹⁴

24
- 0034662749
- L.S. Brinen, E. Hansell, J.M. Cheng, W.R. Roush, J.H. McKerrow, and R.J. Fletterick Structure with folding & design 8 2000 831
- (2000) Structure with Folding & Design , vol.8 , pp. 831
- Brinen, L.S.¹ Hansell, E.² Cheng, J.M.³ Roush, W.R.⁴ McKerrow, J.H.⁵ Fletterick, R.J.⁶

25
- 58149387659
- A. Memic, and M.R. Spaller ChemBioChem 9 2008 2793
- (2008) ChemBioChem , vol.9 , pp. 2793
- Memic, A.¹ Spaller, M.R.²

* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.