Effect of silencing PARG in human colon carcinoma LoVo cells on the ability of HUVEC migration and proliferation

Cancer Gene Therapy

Volumn 19, Issue 10, 2012, Pages 715-722

  Pan, J ^a   Fauzee, N J S ^a   Wang, Y L ^a   Sheng, Y T ^a   Tang, Y ^a   Wang, J Q ^a   Wu, W Q ^a   Yan, J X ^a   Xu, J ^a  

^a CHONGQING MEDICAL UNIVERSITY   (China)

Author keywords

colon cancer; HUVEC; migration; PARG; proliferation; ShRNA

Indexed keywords

FIBROBLAST GROWTH FACTOR; GELATINASE B; GLYCOSIDASE; I KAPPA B KINASE ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERCELLULAR ADHESION MOLECULE 1; LENTIVIRUS VECTOR; MITOGEN ACTIVATED PROTEIN KINASE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE 1; POLY(ADP RIBOSE)GLYCOHYDROLASE; SHORT HAIRPIN RNA; SYNAPTOPHYSIN; UNCLASSIFIED DRUG; VASCULOTROPIN;

ARTICLE; CANCER CELL CULTURE; CELL MIGRATION; CELL PROLIFERATION; COLON CARCINOMA; CONTROLLED STUDY; HUMAN; HUMAN CELL; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; UMBILICAL VEIN ENDOTHELIAL CELL; WESTERN BLOTTING;

ANIMALS; CELL GROWTH PROCESSES; CELL LINE, TUMOR; CELL MOVEMENT; COLONIC NEOPLASMS; DISEASE MODELS, ANIMAL; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE SILENCING; GLYCOSIDE HYDROLASES; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; MICE; MICE, INBRED BALB C; NEOVASCULARIZATION, PATHOLOGIC; SIGNAL TRANSDUCTION; TRANSFECTION;

EID: 84866363462     PISSN: 09291903     EISSN: 14765500     Source Type: Journal    
DOI: 10.1038/cgt.2012.48     Document Type: Article

References (50)

1. Meyer-Ficca ML, Meyer RG, Coyle DL, Jacobson EL, Jacobson MK. Human poly(ADP-ribose) glycohydrolase is expressed in alternative splice variants yielding isoforms that localize to different cell compartments. Exp Cell Res 2004; 297: 521-532.
2. Erde? lyi K, Bai P, Kova?cs I, Szabo? E, Mocsa? r G, Kakuk A et al. Dual role of poly-(ADPribose) glycohydrolase in the regulation of cell death in oxidatively strssed A 549 cells. FASEB J 2009; 23: 3553-3563.
3. Formentini L, Arapistas P, Pittelli M, Jacomelli M, Pitozzi V, Menichetti S et al. Mono-galloyl glucose derivatives are potent poly(ADP-ribose) glycohydrolase( PARG) inhibitors and partially reduce PARP-1-dependent cell death. Br J Pharmacol 2008; 155: 1235-1249.
4. Lin L, Li J, Wang Y-l, Lin X. Relationship of PARG with PARP, VEGF and b-FGF in Colorectal Carcinoma. Chin J Cancer Res 2009; 21: 135-141.
5. Johansson N, Ala-aho R, Uitto V, Grenman R, Fusenig NE, Lopez-Otn C et al. Expression of collagenase/3 (MMP/13) and collagenase/1 (MMP/1) by transformed keratinocytes is dependent on the activity of p38 mitogen/activated protein kinase. J Cell Sci 2000; 113: 227-235.
6. Herrera R. Modulation of hepatocyte growth factor induced scattering of HT29 colon carcinoma cells Involvement of the MAPK pathway. Cancer Res 2001; 61: 383-391.
7. Harris VK, Coticchia CM, Kagan BL, Ahmad S, Wellstein A, Riegel AT. Induction of the angiogenic modulator fibroblast growth factor binding protein by epidermal growth factor is mediated through both MEK/ERK and P38 signal transduction pathway. J Biol Chem 2000; 275: 10802-10811.
8. Pyriochou A, Olah G, Deitch EA, Szabo? C, Papapetropoulos A. Inhibition of angiogenesis by the poly (ADP-ribose) polymerase inhibitor PJ-34. IJMM 2008; 22: 113-118.
9. Mester L, Szabo A, Atlasz T, Szabadfi K, Reglodi D, Kiss P. Protection against chronic hypoperfusion-induced retinal neurodegeneration by PARP inhibition via activation of PI-3-kinase Akt pathway and suppression of JNK and p38 MAP kinases. Neurotox Res 2009; 16: 68-76.
10. Ho JQ, Asagiri M, Hoffmann A, Gosh G. NF-kB potentiates caspase independent hydrogen peroxide induced cell death. PloS One 2011; 6: e16815.
11. Veres B, Radnai B, Gallyas Jr F , Varbiro G, Berente Z, Osz E et al. Regulation of kinase cascades and transcription factors by a Poly (ADP-ribose) polymerase-1 inhibitor, 4-Hydroxyquinazoline, in lipopolysaccharide-induced inflammation in mice. JPET 2004; 310: 247-255.
12. Cai L, Wang YL, Lin X. Effect of PARP inhibitor 5-AIQ on PARP/NF-KB complex and NF-KB activity in murine colon carcinoma CT26 cells. Basic Clin Med 2008; 28: 1156-1159.
13. Moon SJ, Park MK, Oh HJ, Lee SY, Kwok SK, Cho ML et al. Engagement of toll-like receptor 3 induces vascular endothelial growth factor and interleukin-8 in human rheumatoid synovial fibroblasts. Korean J Intern Med 2010; 25: 429-435.
14. Shibata A, Nagaya T, Imai T, Funahashi H, Nakao A, Seo H. Inhibition of NF-kappaB activity decreases the VEGF mRNA expression in MDA-MB-231 breast cancer cells. Breast Cancer Res Treat 2002; 73: 237-243.
15. Xiong HQ, Abbruzzese JL, Lin E, Wang L, Zheng L, Xie K. NF-kappaB activity blockade impairs the angiogenic potential of human pancreatic cancer cells. Int J Cancer 2004; 108: 181-188.
16. Fujioka S, Sclabas GM, Schmidt C, Niu J, Frederick WA, Dong QG et al. Inhibition of constitutive NF-kappa B activity by I kappa B alpha M suppresses tumorigenesis. Oncogene 2003; 22: 1365-1370.
17. Valera FC, Queiroz R, Scrideli C, Tone LG, Anselmo-Lima WT. Expression of transcription factors NF-kB and AP-1 in nasal polyposis. Clin Exp Allergy 2008; 38: 579-585.
18. Pandey MK, Sandur SK, Sung B. Butein a tetrahydtoxychalcone, inhibits nuclear factor (NF)-kB and NF-kB-regulated gene expression through direct inhibition of IB kinase on cysteine179 residue. J Biol Chem 2007; 282: 17340-17350.
19. Tong JS, Zhang QH, Wang ZB, Li S, Yang CR, Fu XQ et al. ER-a36, a novel variant of ER-a, mediates estrogen-stimulated proliferation of endometrial carcinoma cells via the PKCd/ERK pathway. Plos One 2010; 5: e15408.
20. Ok SH, Jeong YS, Kim JG, Lee SM, Sung HJ, Kim HJ et al. C-Jun NH2-terminal kinase contributes to dexmedetomidine-induced contraction in isolated rat aortic smooth muscle. Yonsei Med J 2011; 52: 420-428.
21. Su J, Ruan XC, Zhang YH, She SZ, Xu LX. Effects of morphine and pethidine on the expression of P-glycoprotein in mouse brain microvascular endothelial cells. Nan Fang Yi Ke Da Xue Xue Bao 2010; 30: 1824-1826.
22. Sanda T, Kuwano T, Nakao S, Iida S, Ishida T, Komatsu H et al. Antimyeloma effects of a novel synthetic retinoid Am80 (Tamibarotene) through inhibition of angiogenesis. Leukemia 2005; 19: 901-909.
23. Yang LP, Cheng P, Peng XC, Shi HS, He WH, Cui FY et al. Anti-tumor effect of adenovirus-mediated gene transfer of pigment transfer of pigment epitheliumderived factor on mouse B16-F10 melanoma. J Exp Clin Cancer Res 2009; 28: 75.
24. Luo W, Zhang H, Xu M. Lentiviral vector-a new potential carrier about transgenosis. Jiangsu Pharm Clin Res 2006; 14: 366-370.
25. Min W, Wang ZQ. Poly-(ADP-ribose)glycohydrolase and its therapeutic potential. Front Biosci 2009; 1: 1619-1626.
26. Meyer RG, Meyer-Ficca ML, Jacobson EL, Jacobson MK. Human poly(ADP-ribose) glycohydrolase(PARG) gene and the common promoter sequence it shares with inner mitochondrial membrane translocase 23(TIM23). Gene 2003; 314: 181-190.
27. Koh DW, Lawler AM, Poitras MF, Sasaki M, Wattler S, Nehls MC et al. Failure to degrade poly(ADP-ribose) increased sensitivity to cytotoxicity and early embryonic lethality. PNAS 2004; 101: 17699-17704.
28. Cortes U, Tong WM, Coyle DL, Meyer-Ficca ML, Meyer RG, Petrilli V et al. Depletion of the 110-Kilodalton isoform of poly(ADP-ribose)glycohydrolase increases sensitivity to genotoxic and endotoxic stress in mice. MCB 2004; 24: 7163-7178.
29. Poitras MF, Koh DW, Yu SW, Andrabi SA, Mandir AS, Poirier GG et al. Spatial and functional relationship between poly(ADP-ribose)polymerase-1 and Poly(ADPribose) glycohydrolase in the brain. Neuroscience 2007; 148: 198-211.
30. Miwa M, Matsutani M. PolyADP-ribosylation and cancer. Cancer Sci 2007; 98: 1528-1535.
31. Frizzell KM, Gamble MJ, Berrocal JG, Zhang T, Krishnakumar R, Cen Y et al. Global analysis of transcriptional regulation by Poly-(ADP-ribose) polymerase-1 and poly-(ADP-ribose)glycohydrolase in MCF-7 human breast cancer cells. J Biol Chem 2009; 284: 33926-33938.
32. Li QZ, Wang YL, Li X. Lentivirus PARG-shRNA transfection decreases colon carcinoma lovo cells matrix adhesion, migration and invasion potencies. Basic Clin Med 2010; 30: 237-241.
33. Hazzalin CA, Mahadevan LC. MAPK-regulated transcription:a continuously variable Gene switch? Nat Rev Mol Cell Bio 2002; 3: 30-40.
34. Jukka W, Veli Matti K. Regulation of metalloproteinase expression in tumor invasion. FASEB J 1999; 13: 781-792.
35. Simon C, Hicks MJ, Nemechek AJ, Mehta R, O'Malley Jr BW, Goepfert H et al. PD098059, an inhibitor of ERK1 activation, attenuates the in vivo invasiveness of head and neck squamous cell carcinoma. Br J Cancer 1999; 80: 1412-1419.
36. Noh EM, Kim JS, Hur H, Park BH, Song EK, Han MK et al. Cordycepin inhibits IL-1binduced MMP-1 and MMP-3 expression in rheumatoid arthritis synovial fibroblasts. Rheumatology 2009; 48: 45-48.
37. Johansson N, Ala-aho R, Uitto V, Gre?nman R, Fusenig NE, Lopez-Otn C et al. Expression of collagenase/3 (MMP/13) and collagenase/1 (MMP/1) by transformed keratinocytes is dependent on the activity of p38 mitogen/activated protein kinase. J Cell Sci 2000; 113: 227-235.
38. Zhang JQ, Wan YL, Liu YC. TF/F Vlla complex induce the expression of MMP-7mRNA via P38 signal pathway in LOVO cells of colon cancer in vitro. Chin J Gen Surg 2007; 22: 918-921.
39. Bancroft CC, Chen Z, Dong G, Sunwoo JB, Yeh N, Park C et al. Coexpression of proangiogenic factors IL/8 and VEGF by human head and neck squamous cell carcinoma involves coactivation by MEK/MAPK and IKK/NF-kappaB signal pathways. Clin Cancer Res 2001; 7: 435-442.
40. Ckajima E, Thorgeirsson UP. Different regulation of vascular endothelial growth factor expression by the ERK and P38 kinase pathways in V/ras, V/raf and V/myc transformed cells. Biochem Biophys Res Commun 2000; 270: 108-111.
41. Erdèlyi K, Kiss A, Bakondi E, Bai P, Szabo C, Gergely P et al. Gallotannin inhibits the expression of chemokines and inflammatory cytokines in A549 cells. Mol Pharmacol 2005; 68: 895-904.
42. Nakajima H, Nagaso H, Kakui N, Ishikawa M, Hiranuma T, Hoshiko S. Critical role of the automodification of poly(ADP-ribose)polymerase-1 in nuclear factor-kappaB dependent gene expression in primary cultured mouse glial cells. J Biol Chem 2004; 279: 42774-42786.
43. Tikoo K, Bhatt DK, Gaikwad AB, Sharma V, Kabra DG. Differential effects of tannic acid on cisplatin induced nephrotoxicity in rats. FEBS Lett 2007; 581: 2027-2035.
44. Hao LX, Wang YL, Li YY. Correlation of PARP expression with P-selectin and ICAM-1 expression in colorectal carcinoma. Basic Clin Med 2006; 26: 882-887.
45. Fossey SL, Bear MD, Kisseberth WC, Pennell M, London CA. Oncostatin M promotes STAT3 activation, VEGF production, and invasion in osteosarcoma cell lines. BMC Cancer 2011; 11: 125.
46. Li KX, Li AM, Zhang JH. Effects of TrkB-BDNF signal pathway on synthesis and secretion of vascular endothelial growth factor in human neuroblastoma cells. Zhongguo Dang Dai Er Ke Za Zhi 2011; 13: 240-243.
47. Meijer K, de Vries M, Al-Lahham S, Bruinenberg M, Weening D, Dijkstra M et al. Human primary adipocytes exhibit immune cell function:adipocytes prime inflammation independent of macrophages. PLoS One 2011; 6: e17154.
48. Choi JA, Jin HJ, Jung S, Yang E, Choi JS, Chung SH et al. Effects of amniotic membrane suspension in human corneal wound healing in vitro. Mol Vis 2009; 5: 2230-2238.
49. Jiang YB, Zhang XL, Tang YL, Ma GS, Shen CX, Wei Q et al. Effects of heme oxygenase-1 gene modulated mesenchymal stem cells on vasculogenesis in ischemic swine hearts. Chin Med J 2011; 124: 401-407.
50. Firoozrai M, Fallah S, Khorrmizadeh MR. Angiotensin II induces NF-kB, JNK and p38 MAPK activation in monocytic cells and increases matrix metalloproteinase-9 expression in a PKC-andRho kinase-dependent manner. Braz J Med Biol Res 2011; 44: 193-199.