Structures of the ozonolysis products and ozonolysis pathway of aflatoxin B1 in acetonitrile solution

Journal of Agricultural and Food Chemistry

Volumn 60, Issue 36, 2012, Pages 9364-9370

  Diao, Enjie ^a   Shan, Changpo ^a   Hou, Hanxue ^a   Wang, Shanshan ^b   Li, Minghua ^c   Dong, Haizhou ^a  

^a SHANDONG AGRICULTURAL UNIVERSITY   (China)

^b Shandong Analysis and Test Center   (China)

^c SHANDONG PEANUT RESEARCH INSTITUTE   (China)

Author keywords

Aflatoxin B1; mechanism; ozone; ozonolysis products; structure

Indexed keywords

ACCURATE MASS; ACETONITRILE SOLUTIONS; AFLATOXIN B; AFLATOXIN B1; BENZENE RING; DOUBLE BONDS; ELECTROPHILIC REACTION; FURAN RING; LACTONE MOIETY; MOLECULAR FORMULA; OXIDATIVE PATHWAYS; OZONE CONCENTRATION; OZONOLYSIS; STRUCTURAL IDENTIFICATION; TIME-OF-FLIGHT MASS SPECTRA;

ACETONITRILE; AFLATOXINS; BENZENE; DETOXIFICATION; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; MECHANISMS; OZONE LAYER; STRUCTURE (COMPOSITION); TOXICITY;

OZONE;

ACETONITRILE; ACETONITRILE DERIVATIVE; AFLATOXIN B1; OZONE;

CHEMICAL STRUCTURE; CHEMISTRY; CONFERENCE PAPER; OXIDATION REDUCTION REACTION;

ACETONITRILES; AFLATOXIN B1; MOLECULAR STRUCTURE; OXIDATION-REDUCTION; OZONE;

ANIMALIA;

EID: 84866360560     PISSN: 00218561     EISSN: 15205118     Source Type: Journal    
DOI: 10.1021/jf302528e     Document Type: Conference Paper

References (27)

1. Juan, C.; Zinedine, A.; Molto, J. C.; Idrissi, L.; Manes, J. Aflatoxin levels in dried fruits and nuts from Rabat-Sale, Morocco Food Control 2008, 19, 849-853
2. Turner, N.; Subrahmanyam, S.; Piletsky, S. Analytical methods for determination of mycotoxins: A review Anal. Chim. Acta 2009, 632, 168-180
3. Arzandeh, S.; Jinap, S.; Lioe, H. Aflatoxin in raw peanut kernels marketed in Malaysia J. Food Drug Anal. 2010, 18, 44-50
4. Shenasi, M.; Aidoo, K. E.; Candlish, A. A. G. Microflora of date fruits and production of aflatoxins at various stages of maturation Int. J. Food Microbiol. 2002, 79, 113-119
5. Proctor, A. D.; Ahmedna, M.; Kumar, J. V.; Goktepe, I. Degradation of aflatoxins in peanut kernels/flour by gaseous ozonation and mild heat treatment Food Addit. Contam. 2004, 21, 786-793
6. Nakai, V.; de Oliveira Rocha, L.; Goncalez, E.; Fonseca, H.; Ortega, E.; Corrêa, B. Distribution of fungi and toxins in a stored peanut variety Food Chem. 2008, 106, 285-290
7. Bhat, R.; Rai, R. V.; Karim, A. A. Mycotoxins in food and feed: Present status and future concerns Compr. Rev. Food Sci. Food Saf. 2010, 9, 57-81
8. Misra, J. B. A mathematical approach to comprehensive evaluation of quality in groundnut J. Food Compos. Anal. 2004, 17, 69-79
9. Burlingame, B.; Pineiro, M. The essential balance: Risks and benefits in food safety and quality J. Food Compos. Anal. 2007, 20, 139-146
10. Netke, S. P.; Roomi, M. W.; Tsao, C.; Niedwiecki, A. Ascorbic acid protects Guinea pigs from acute aflatoxin toxicity Toxicol. Appl. Pharmacol. 1997, 143, 429-435
11. 1 detoxification on the physicochemical properties and quality of ground nut meal Food Chem. 2000, 70, 483-487
12. Haskard, C.; Binnion, C.; Ahokas, J. Factors affecting the sequestration of aflatoxin by Lactobacillus rhamnosus strain GG Chem.-Biol. Interact. 2000, 128, 39-49
13. Prudente, A. D.; King, J. M. Efficacy and safety evaluation of ozonation to degrade aflatoxin in corn J. Food Sci. 2002, 67, 2866-2872
14. Akbas, M. Y.; Ozdemir, M. Effect of different ozone treatments on aflatoxin degradation and physicochemical properties of pistachios J. Sci. Food Agric. 2006, 86, 2099-2104
15. 1 in dried figs Food Chem. Toxicol. 2008, 46, 3593-3597
16. Alencar, E. R.; Faroni, L. R. D.; Soares, N. F. F.; Silva, W. A.; Carvalho, M. C. S. Efficacy of ozone as a fungicidal and detoxifying agent of aflatoxins in peanuts J. Sci. Food Agric. 2011, 92, 899-905
17. McKenzie, K. S.; Sarr, A. B.; Mayura, K.; Bailey, R. H.; Miller, D. R.; Rogers, T. D.; Norred, W. P.; Voss, K. A.; Plattner, R. D.; Kubena, L. F.; Phillips, T. D. Oxidative degradation and detoxification of mycotoxins using a novel source of ozone Food Chem. Toxicol. 1997, 35, 807-820
18. Prudente, A. D. Evaluation of aflatoxin-related products from ozonated corn. Doctoral Dissertation, Louisiana State University, Baton Rouge, LA, 2008; p 99.
19. 1 in aqueous medium by ultra-performance liquid chromatography-quadrupole time-of-flight mass spectrometry J. Mass Spectrom. 2010, 45, 553-559
20. 1 Chromatography 2010, 71, 107-112
21. 1 in methanol-water solution J. Hazard. Mater. 2011, 192, 1192-1202
22. Mortishire-Smith, R. J.; O'Connor, D.; Castro-Perez, J. M.; Kirby, J. Accelerated throughput metabolic route screening in early drug discovery using high-resolution liquid chromatography/quadrupole time-of-flight mass spectrometry and automated data analysis Rapid Commun. Mass Spectrom. 2005, 19, 2659-2670
23. E with mass defect filtering for in vitro and in vivo metabolite identification Rapid Commun. Mass Spectrom. 2007, 21, 1485-1496
24. Lin, Z. S.; Le, J.; Hong, Z. Y. Liquid chromatography-quadrupole-time-of- fight mass spectrometry and its application in the metabolism (metabolomics) research of traditional Chinese medicines Chin. Pharm. J. (Taipei, Taiwan) 2012, 47, 401-405
25. Wogan, G. N.; Edwards, G. S.; Newberne, P. M. Structure-activity relationships in toxicity and carcinogenicity of aflatoxins and analogs Cancer Res. 1971, 31, 1936-1942
26. 1 induced hepatotoxicity Biochem. Biophys. Res. Commun. 1983, 114, 813-821
27. Verma, R. J. Aflatoxin cause DNA damage Int. J. Hum. Genet. 2004, 4, 231-236