Novel potent anticonvulsant agent containing a tetrahydroisoquinoline skeleton

Journal of Medicinal Chemistry

Volumn 49, Issue 18, 2006, Pages 5618-5622

  Gitto, Rosaria ^a   Caruso, Roberta ^a   Pagano, Benedetta ^a   De Luca, Laura ^a   Citraro, Rita ^b   Russo, Emilio ^b   De Sarro, Giovambattista ^b   Chimirri, Alba ^a  

^a UNIVERSITY OF MESSINA   (Italy)

^b UNIVERSITY MAGNA GRAECIA OF CATANZARO   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

1 (4' BROMOPHENYL) 6,7 DIMETHOXY 2 (PIPERIDIN 1 YLACETYL)DERIVATIVE; ALPHA AMINO 3 HYDROXY 5 METHYL 4 ISOXAZOLEPROPIONIC ACID; AMPA RECEPTOR ANTAGONIST; ANTICONVULSIVE AGENT; TALAMPANEL; TETRAHYDROISOQUINOLINE DERIVATIVE; UNCLASSIFIED DRUG;

ADD ON THERAPY; ANIMAL TISSUE; ARTICLE; CALCIUM CURRENT; DERIVATIZATION; DRUG POTENCY; ELECTROPHYSIOLOGY; EPILEPSY; GABAERGIC TRANSMISSION; MALE; NERVE GROWTH; NONHUMAN; RAT; STRUCTURE ACTIVITY RELATION; SYNTHESIS;

ACOUSTIC STIMULATION; ANIMALS; ANTICONVULSANTS; ISOQUINOLINES; MALE; MICE; MICE, INBRED DBA; OLFACTORY PATHWAYS; PIPERIDINES; RATS; RATS, WISTAR; RECEPTORS, AMPA; SEIZURES; STRUCTURE-ACTIVITY RELATIONSHIP; TETRAHYDROISOQUINOLINES;

EID: 33748533497     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm060411b     Document Type: Article

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