NLRP10 enhances shigella-induced pro-inflammatory responses

Cellular Microbiology

Volumn 14, Issue 10, 2012, Pages 1568-1583

  Lautz, Katja ^a   Damm, Anna ^a   Menning, Maureen ^a   Wenger, Julia ^b   Adam, Alexander C ^a   Zigrino, Paola ^a   Kremmer, Elisabeth ^c   Kufer, Thomas A ^a  

^a UNIVERSITY OF COLOGNE   (Germany)

^b UNIVERSITY OF SALZBURG   (Austria)

^c INSTITUTE OF EPIDEMIOLOGY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; NUCLEOTIDE BINDING OLIGOMERIZATION DOMAIN LIKE RECEPTOR; NUCLEOTIDE BINDING OLIGOMERIZATION DOMAIN LIKE RECEPTOR PROTEIN 10; SMALL INTERFERING RNA; SYNAPTOPHYSIN; UNCLASSIFIED DRUG;

ARTICLE; BACTERIAL INFECTION; CELL MEMBRANE; CYTOKINE RELEASE; ENZYME ACTIVITY; EPITHELIUM CELL; FIBROBLAST; HUMAN; INFLAMMATION; INNATE IMMUNITY; NONHUMAN; PRIORITY JOURNAL; SHIGELLA FLEXNERI; SIGNAL TRANSDUCTION; SKIN CELL;

ADENOSINE TRIPHOSPHATASES; CARRIER PROTEINS; CELLS, CULTURED; CYTOKINES; EPITHELIAL CELLS; FIBROBLASTS; GENE KNOCKDOWN TECHNIQUES; HUMANS; IMMUNITY, INNATE; MAP KINASE SIGNALING SYSTEM; NF-KAPPA B; NOD1 SIGNALING ADAPTOR PROTEIN; PROTEIN BINDING; PROTEIN INTERACTION MAPPING; SHIGELLA FLEXNERI;

BACTERIA (MICROORGANISMS); SHIGELLA; SHIGELLA FLEXNERI;

EID: 84866343440     PISSN: 14625814     EISSN: 14625822     Source Type: Journal    
DOI: 10.1111/j.1462-5822.2012.01822.x     Document Type: Article

References (50)

1. Barnich, N., Aguirre, J.E., Reinecker, H.C., Xavier, R., and Podolsky, D.K. (2005) Membrane recruitment of NOD2 in intestinal epithelial cells is essential for nuclear factor-{kappa}B activation in muramyl dipeptide recognition. J Cell Biol 170 : 21-26.
2. Bielig, H., Velder, J., Saiai, A., Menning, M., Meemboor, S., Kalka-Moll, W., etal. (2010) Anti-inflammatory arene-chromium complexes acting as specific inhibitors of NOD2 signalling. ChemMedChem 5 : 2065-2071.
3. Broz, P., von Moltke, J., Jones, J.W., Vance, R.E., and Monack, D.M. (2010) Differential requirement for caspase-1 autoproteolysis in pathogen-induced cell death and cytokine processing. Cell Host Microbe 8 : 471-483.
4. Chen, G.Y., Liu, M., Wang, F., Bertin, J., and Nunez, G. (2011a) A functional role for Nlrp6 in intestinal inflammation and tumorigenesis. J Immunol 186 : 7187-7194.
5. Chen, Y., Lind Enoksson, S., Johansson, C., Karlsson, M.A., Lundeberg, L., Nilsson, G., etal. (2011b) The expression of BAFF, APRIL and TWEAK is altered in eczema skin but not in the circulation of atopic and seborrheic eczema patients. PLoS ONE 6 : e22202.
6. Clerc, P., and Sansonetti, P.J. (1987) Entry of Shigella flexneri into HeLa cells: evidence for directed phagocytosis involving actin polymerization and myosin accumulation. Infect Immun 55 : 2681-2688.
7. Correa, R.G., Khan, P.M., Askari, N., Zhai, D., Gerlic, M., Brown, B., etal. (2011) Discovery and characterization of 2-aminobenzimidazole derivatives as selective NOD1 inhibitors. Chem Biol 18 : 825-832.
8. Damiano, J.S., Newman, R.M., and Reed, J.C. (2004) Multiple roles of CLAN (caspase-associated recruitment domain, leucine-rich repeat, and NAIP CIIA HET-E, and TP1-containing protein) in the mammalian innate immune response. J Immunol 173 : 6338-6345.
9. Eisenbarth, S.C., Williams, A., Colegio, O.R., Meng, H., Strowig, T., Rongvaux, A., etal. (2012) NLRP10 is a NOD-like receptor essential to initiate adaptive immunity by dendritic cells. Nature 484 : 510-513.
10. Eitas, T.K., and Dangl, J.L. (2010) NB-LRR proteins: pairs, pieces, perception, partners, and pathways. Curr Opin Plant Biol 13 : 472-477.
11. Elinav, E., Strowig, T., Kau, A.L., Henao-Mejia, J., Thaiss, C.A., Booth, C.J., etal. (2011) NLRP6 inflammasome regulates colonic microbial ecology and risk for colitis. Cell 145 : 745-757.
12. Fritz, J.H., Ferrero, R.L., Philpott, D.J., and Girardin, S.E. (2006) Nod-like proteins in immunity, inflammation and disease. Nat Immunol 7 : 1250-1257.
13. Girardin, S.E., Tournebize, R., Mavris, M., Page, A.L., Li, X., Stark, G.R., etal. (2001) CARD4/Nod1 mediates NF-kappaB and JNK activation by invasive Shigella flexneri EMBO Rep 2 : 736-742.
14. Girardin, S.E., Boneca, I.G., Carneiro, L.A., Antignac, A., Jehanno, M., Viala, J., etal. (2003a) Nod1 detects a unique muropeptide from gram-negative bacterial peptidoglycan. Science 300 : 1584-1587.
15. Girardin, S.E., Boneca, I.G., Viala, J., Chamaillard, M., Labigne, A., Thomas, G., etal. (2003b) Nod2 is a general sensor of peptidoglycan through muramyl dipeptide (MDP) detection. J Biol Chem 278 : 8869-8872.
16. Grenier, J.M., Wang, L., Manji, G.A., Huang, W.J., Al-Garawi, A., Kelly, R., etal. (2002) Functional screening of five PYPAF family members identifies PYPAF5 as a novel regulator of NF-kappaB and caspase-1. FEBS Lett 530 : 73-78.
17. Hsu, L.C., Ali, S.R., McGillivray, S., Tseng, P.H., Mariathasan, S., Humke, E.W., etal. (2008) A NOD2-NALP1 complex mediates caspase-1-dependent IL-1beta secretion in response to Bacillus anthracis infection and muramyl dipeptide. Proc Natl Acad Sci USA 105 : 7803-7808.
18. Imamura, R., Wang, Y., Kinoshita, T., Suzuki, M., Noda, T., Sagara, J., etal. (2010) Anti-inflammatory activity of PYNOD and its mechanism in humans and mice. J Immunol 184 : 5874-5884.
19. Inohara, N., Ogura, Y., Fontalba, A., Gutierrez, O., Pons, F., Crespo, J., etal. (2003) Host recognition of bacterial muramyl dipeptide mediated through NOD2. Implications for Crohn's disease. J Biol Chem 278 : 5509-5512.
20. Khan, P.M., Correa, R.G., Divlianska, D.B., Peddibhotla, S., Sessions, E.H., Magnuson, G., etal. (2011) Identification of inhibitors of NOD1-induced nuclear factor-kappaB activation. ACS Med Chem Lett 2 : 780-785.
21. Kinoshita, T., Wang, Y., Hasegawa, M., Imamura, R., and Suda, T. (2005) PYPAF3, a PYRIN-containing APAF-1-like protein, is a feedback regulator of caspase-1-dependent interleukin-1beta secretion. J Biol Chem 280 : 21720-21725.
22. Kofoed, E.M., and Vance, R.E. (2011) Innate immune recognition of bacterial ligands by NAIPs determines inflammasome specificity. Nature 477 : 592-595.
23. Kufer, T.A. (2008) Signal transduction pathways used by NLR-type innate immune receptors. Mol Biosyst 4 : 380-386.
24. Kufer, T.A., Kremmer, E., Banks, D.J., and Philpott, D.J. (2006) Role for erbin in bacterial activation of Nod2. Infect Immun 74 : 3115-3124.
25. Kufer, T.A., Kremmer, E., Adam, A.C., Philpott, D.J., and Sansonetti, P.J. (2008) The pattern-recognition molecule Nod1 is localized at the plasma membrane at sites of bacterial interaction. Cell Microbiol 10 : 477-486.
26. Lamkanfi, M., Mueller, J.L., Vitari, A.C., Misaghi, S., Fedorova, A., Deshayes, K., etal. (2009) Glyburide inhibits the Cryopyrin/Nalp3 inflammasome. J Cell Biol 187 : 61-70.
27. Lech, M., Avila-Ferrufino, A., Skuginna, V., Susanti, H.E., and Anders, H.J. (2010) Quantitative expression of RIG-like helicase, NOD-like receptor and inflammasome-related mRNAs in humans and mice. Int Immunol 22 : 717-728.
28. McDonald, C., Chen, F.F., Ollendorff, V., Ogura, Y., Marchetto, S., Lecine, P., etal. (2005) A role for Erbin in the regulation of Nod2-dependent NF-kappaB signaling. J Biol Chem 280 : 40301-40309.
29. Martinon, F., Burns, K., and Tschopp, J. (2002) The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-beta. Mol Cell 10 : 417-426.
30. Neerincx, A., Rodriguez, G., Steimle, V., and Kufer, T.A. (2012) NLRC5 controls basal MHC class I gene expression in an MHC-enhanceosome dependent manner. J Immunol 188 : 4940-4950.
31. Nigro, G., Fazio, L.L., Martino, M.C., Rossi, G., Tattoli, I., Liparoti, V., etal. (2008) Muramylpeptide shedding modulates cell sensing of Shigella flexneri Cell Microbiol 10 : 682-695.
32. Normand, S., Delanoye-Crespin, A., Bressenot, A., Huot, L., Grandjean, T., Peyrin-Biroulet, L., etal. (2011) Nod-like receptor pyrin domain-containing protein 6 (NLRP6) controls epithelial self-renewal and colorectal carcinogenesis upon injury. Proc Natl Acad Sci USA 108 : 9601-9606.
33. Pan, Q., Mathison, J., Fearns, C., Kravchenko, V.V., Da Silva Correia, J., Hoffman, H.M., etal. (2007) MDP-induced interleukin-1beta processing requires Nod2 and CIAS1/NALP3. J Leukoc Biol 82 : 177-183.
34. Pedron, T., Thibault, C., and Sansonetti, P.J. (2003) The invasive phenotype of Shigella flexneri directs a distinct gene expression pattern in the human intestinal epithelial cell line Caco-2. J Biol Chem 278 : 33878-33886.
35. Philpott, D.J., Yamaoka, S., Israel, A., and Sansonetti, P.J. (2000) Invasive Shigella flexneri activates NF-kappa B through a lipopolysaccharide-dependent innate intracellular response and leads to IL-8 expression in epithelial cells. J Immunol 165 : 903-914.
36. Proell, M., Riedl, S.J., Fritz, J.H., Rojas, A.M., and Schwarzenbacher, R. (2008) The Nod-like receptor (NLR) family: a tale of similarities and differences. PLoS ONE 3 : e2119.
37. Reith, W., and Mach, B. (2001) The bare lymphocyte syndrome and the regulation of MHC expression. Annu Rev Immunol 19 : 331-373.
38. Schroder, K., and Tschopp, J. (2010) The inflammasomes. Cell 140 : 821-832.
39. Schroeder, G.N., and Hilbi, H. (2008) Molecular pathogenesis of Shigella spp.: controlling host cell signaling, invasion, and death by type III secretion. Clin Microbiol Rev 21 : 134-156.
40. Shigeoka, A.A., Mueller, J.L., Kambo, A., Mathison, J.C., King, A.J., Hall, W.F., etal. (2010) An inflammasome-independent role for epithelial-expressed Nlrp3 in renal ischemia-reperfusion injury. J Immunol 185 : 6277-6285.
41. Suzuki, T., Franchi, L., Toma, C., Ashida, H., Ogawa, M., Yoshikawa, Y., etal. (2007) Differential regulation of caspase-1 activation, pyroptosis, and autophagy via Ipaf and ASC in Shigella-infected macrophages. PLoS Pathog 3 : e111.
42. Tanabe, T., Chamaillard, M., Ogura, Y., Zhu, L., Qiu, S., Masumoto, J., etal. (2004) Regulatory regions and critical residues of NOD2 involved in muramyl dipeptide recognition. EMBO J 23 : 1587-1597.
43. Ting, J.P., Willingham, S.B., and Bergstralh, D.T. (2008) NLRs at the intersection of cell death and immunity. Nat Rev 8 : 372-379.
44. Travassos, L.H., Carneiro, L.A., Ramjeet, M., Hussey, S., Kim, Y.G., Magalhaes, J.G., etal. (2010) Nod1 and Nod2 direct autophagy by recruiting ATG16L1 to the plasma membrane at the site of bacterial entry. Nat Immunol 11 : 55-62.
45. Wagner, R.N., Proell, M., Kufer, T.A., and Schwarzenbacher, R. (2009) Evaluation of Nod-like receptor (NLR) effector domain interactions. PLoS ONE 4 : e4931.
46. Wang, Y., Hasegawa, M., Imamura, R., Kinoshita, T., Kondo, C., Konaka, K., and Suda, T. (2004) PYNOD, a novel Apaf-1/CED4-like protein is an inhibitor of ASC and caspase-1. Int Immunol 16 : 777-786.
47. Willingham, S.B., Bergstralh, D.T., O'Connor, W., Morrison, A.C., Taxman, D.J., Duncan, J.A., etal. (2007) Microbial pathogen-induced necrotic cell death mediated by the inflammasome components CIAS1/cryopyrin/NLRP3 and ASC. Cell Host Microbe 2 : 147-159.
48. Zhao, Y., Yang, J., Shi, J., Gong, Y.N., Lu, Q., Xu, H., etal. (2011) The NLRC4 inflammasome receptors for bacterial flagellin and type III secretion apparatus. Nature 477 : 596-600.
49. Zigrino, P., Drescher, C., and Mauch, C. (2001) Collagen-induced proMMP-2 activation by MT1-MMP in human dermal fibroblasts and the possible role of alpha2beta1 integrins. Eur J Cell Biol 80 : 68-77.
50. Zurek, B., Proell, M., Wagner, R.N., Schwarzenbacher, R., and Kufer, T.A. (2012) Mutational analysis of human NOD1 and NOD2 NACHT domains reveals different modes of activation. Innate Immun 18 : 100-111.