Discovery and characterization of 2-aminobenzimidazole derivatives as selective NOD1 inhibitors

Chemistry and Biology

Volumn 18, Issue 7, 2011, Pages 825-832

  Correa, Ricardo G ^a   Khan, Pasha M ^a   Askari, Nadav ^a   Zhai, Dayong ^a   Gerlic, Motti ^a   Brown, Brock ^b   Magnuson, Gavin ^b   Spreafico, Roberto ^a   Albani, Salvatore ^a   Sergienko, Eduard ^b   Diaz, Paul W ^a   Roth, Gregory P ^a   Reed, John C ^a  

^a BURNHAM INSTITUTE   (United States)

^b EASTERN VIRGINIA MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 AMINOBENZIMIDAZOLE; 2-AMINOBENZIMIDAZOLE; BENZIMIDAZOLE DERIVATIVE; CASPASE RECRUITMENT DOMAIN PROTEIN 4; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN;

ARTICLE; CELL CULTURE; CELL LINE; CHEMISTRY; DENDRITIC CELL; DRUG ANTAGONISM; DRUG EFFECT; DRUG SCREENING; GENETICS; HIGH THROUGHPUT SCREENING; HUMAN; IMMUNOLOGY; REPORTER GENE; SIGNAL TRANSDUCTION;

BENZIMIDAZOLES; CELL LINE; CELLS, CULTURED; DENDRITIC CELLS; DRUG EVALUATION, PRECLINICAL; GENES, REPORTER; HIGH-THROUGHPUT SCREENING ASSAYS; HUMANS; NF-KAPPA B; NOD1 SIGNALING ADAPTOR PROTEIN; SIGNAL TRANSDUCTION;

BACTERIA (MICROORGANISMS);

EID: 79960965328     PISSN: 10745521     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chembiol.2011.06.009     Document Type: Article

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