Ablation of the Regulatory IE1 Protein of Murine Cytomegalovirus Alters In Vivo Pro-inflammatory TNF-alpha Production during Acute Infection

PLoS Pathogens

Volumn 8, Issue 8, 2012, Pages

  Rodríguez Martín, Sara ^a   Kropp, Kai Alexander ^a   Wilhelmi, Vanessa ^b   Lisnic, Vanda Juranic ^c   Hsieh, Wei Yuan ^a   Blanc, Mathieu ^a   Livingston, Andrew ^a   Busche, Andreas ^d   Tekotte, Hille ^e   Messerle, Martin ^d   Auer, Manfred ^f   Fraser, Iain ^g   Jonjic, Stipan ^c   Angulo, Ana ^h   Reddehase, Matthias J ^b   Ghazal, Peter ^a  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

^b UNIVERSITY MEDICAL CENTER MAINZ   (Germany)

^c UNIVERSITY OF RIJEKA   (Croatia)

^d HANNOVER MEDICAL SCHOOL   (Germany)

^e UNIVERSITY OF EDINBURGH   (United Kingdom)

^f UNIVERSITY OF EDINBURGH   (United Kingdom)

^g NATIONAL INSTITUTES OF HEALTH   (United States)

^h INSTITUT D INVESTIGACIONS BIOMÈDIQUES AUGUST PI I SUNYER IDIBAPS   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

BETA INTERFERON; INTERLEUKIN 10; REGULATOR PROTEIN; REGULATORY IE1 PROTEIN; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOMEGALOVIRUS; CYTOMEGALOVIRUS INFECTION; FEMALE; GENE DELETION; GENE EXPRESSION REGULATION; GENE FUNCTION; IE1 GENE; IMMEDIATE EARLY GENE; IMMEDIATE EARLY GENE 1; IMMUNE RESPONSE; IMMUNOREGULATION; IN VITRO STUDY; IN VIVO STUDY; MACROPHAGE; MALE; MOUSE; MOUSE STRAIN; NONHUMAN; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; VIRUS GENE; VIRUS MUTANT; VIRUS REPLICATION;

ANIMALS; CELL LINE; CYTOKINES; DNA REPLICATION; DNA, VIRAL; FEMALE; GENE EXPRESSION REGULATION, VIRAL; HERPESVIRIDAE INFECTIONS; IMMEDIATE-EARLY PROTEINS; LIVER; MACROPHAGES; MALE; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MUROMEGALOVIRUS; PHENOTYPE; SIGNAL TRANSDUCTION; TUMOR NECROSIS FACTOR-ALPHA; VIRAL PROTEINS; VIRUS REPLICATION;

MURID HERPESVIRUS 1;

EID: 84866163013     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1002901     Document Type: Article

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