Combined chromatin and expression analysis reveals specific regulatory mechanisms within cytokine genes in the macrophage early immune response

PLoS ONE

Volumn 7, Issue 2, 2012, Pages

  Iglesias, Maria ^a   Reilly, Sarah Jayne ^a   Emanuelsson, Olof ^b   Sennblad, Bengt ^a   Najafabadi, Mohammad ^b   Folkersen, Lasse ^a   Mälarstig, Anders ^a   Lagergren, Jens ^b   Eriksson, Per ^a   Hamsten, Anders ^a,c   Odeberg, Jacob ^a,b,c  

^a KAROLINSKA INSTITUTE   (Sweden)

^b ROYAL INSTITUTE OF TECHNOLOGY   (Sweden)

^c KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; HISTONE H3; LIPOPOLYSACCHARIDE; PREGNANCY SPECIFIC BETA1 GLYCOPROTEIN; RNA POLYMERASE II; SERINE; TATA BINDING PROTEIN; TUMOR NECROSIS FACTOR; HISTONE; MESSENGER RNA;

ARTICLE; CHROMATIN ASSEMBLY AND DISASSEMBLY; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; CPG ISLAND; EARLY RESPONSE GENE; GENE EXPRESSION; GENE EXPRESSION PROFILING; GENE SEQUENCE; GENETIC ASSOCIATION; HISTONE ACETYLATION; IMMUNE RESPONSE; IMMUNOSTIMULATION; INNATE IMMUNITY; MACROPHAGE; MACROPHAGE ACTIVATION; MARKER GENE; PROMOTER REGION; PROTEIN BINDING; REGULATOR GENE; REGULATORY MECHANISM; TNF GENE; TRANSCRIPTION INITIATION; TRANSCRIPTION REGULATION; UPREGULATION; BIOLOGICAL MODEL; CELL DIFFERENTIATION; CHEMISTRY; CHROMATIN; CYTOLOGY; DNA MICROARRAY; GENETICS; HUMAN; IMMUNE SYSTEM; INFLAMMATION; METABOLISM; MONOCYTE; MULTIGENE FAMILY;

CELL DIFFERENTIATION; CHROMATIN; CHROMATIN IMMUNOPRECIPITATION; CPG ISLANDS; CYTOKINES; GENE EXPRESSION PROFILING; GENOME-WIDE ASSOCIATION STUDY; HISTONES; HUMANS; IMMUNE SYSTEM; IMMUNITY, INNATE; INFLAMMATION; MACROPHAGES; MODELS, BIOLOGICAL; MONOCYTES; MULTIGENE FAMILY; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PROMOTER REGIONS, GENETIC; PROTEIN BINDING; RNA, MESSENGER; SERINE;

EID: 84857612511     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0032306     Document Type: Article

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