SptP, a Salmonella typhimurium type III-secreted protein, inhibits the mitogen-activated protein kinase pathway by inhibiting Raf activation

Cellular Microbiology

Volumn 5, Issue 4, 2003, Pages 267-275

  Lin, Stanley L ^a,b   Le, Trung X ^b   Cowen, Daniel S ^a  

^a RUTGERS ROBERT WOOD JOHNSON MEDICAL SCHOOL   (United States)

^b Vion Pharmaceuticals Incorporated   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL PROTEIN; GUANOSINE TRIPHOSPHATASE; GUANOSINE TRIPHOSPHATASE ACTIVATING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE KINASE; MUTANT PROTEIN; PROTEIN SPTP; PROTEIN TYROSINE KINASE; RAF PROTEIN; SALMONELLOSIS VACCINE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

CELL MEMBRANE; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; GENE DELETION; GENE MUTATION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; MACROPHAGE; NONHUMAN; NONVIRAL GENE DELIVERY SYSTEM; NONVIRAL GENE THERAPY; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; PROTEIN SECRETION; REGULATORY MECHANISM; REVIEW; SALMONELLA TYPHIMURIUM; SALMONELLOSIS;

ANIMALS; BACTERIAL PROTEINS; CELL LINE; ENZYME ACTIVATION; GENES, FOS; GENES, REPORTER; HUMANS; MAP KINASE KINASE 1; MAP KINASE SIGNALING SYSTEM; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; MITOGEN-ACTIVATED PROTEIN KINASES; MODELS, BIOLOGICAL; PROMOTER REGIONS (GENETICS); PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS C-RAF; SALMONELLA TYPHIMURIUM; TRANS-ACTIVATION (GENETICS); TUMOR NECROSIS FACTOR-ALPHA;

BACTERIA (MICROORGANISMS); SALMONELLA; SALMONELLA TYPHIMURIUM;

EID: 0242500994     PISSN: 14625814     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1462-5822.2003.t01-1-00274.x     Document Type: Review

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