Deletion of the rat cytomegalovirus immediate-early 1 gene results in a virus capable of establishing latency, but with lower levels of acute virus replication and latency that compromise reactivation efficiency

Journal of General Virology

Volumn 91, Issue 3, 2010, Pages 616-621

  Sandford, Gordon R ^a   Schumacher, Uwe ^b   Ettinger, Jakob ^b   Brune, Wofram ^b   Hayward, Gary S ^a   Burns, William H ^a   Voigt, Sebastian ^b  

^a JOHNS HOPKINS UNIVERSITY   (United States)

^b ROBERT KOCH INSTITUTE   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

IMMEDIATE EARLY PROTEIN; IMMEDIATE EARLY PROTEIN 1; IMMEDIATE EARLY PROTEIN 2; UNCLASSIFIED DRUG; VIRUS DNA; VIRUS PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL CULTURE; CONTROLLED STUDY; CYTOMEGALOVIRUS; EX VIVO STUDY; EXPLANT; FIBROBLAST; GENE DELETION; IN VIVO STUDY; NONHUMAN; PRIORITY JOURNAL; PROMYELOCYTIC LEUKEMIA; PROTEIN FUNCTION; PROTEIN SYNTHESIS; QUANTITATIVE ANALYSIS; RAT; SALIVARY GLAND; SPLEEN; VIRUS GENOME; VIRUS LATENCY; VIRUS REACTIVATION; VIRUS REPLICATION;

ANIMALS; CELLS, CULTURED; DNA, VIRAL; FIBROBLASTS; HERPESVIRIDAE INFECTIONS; IMMEDIATE-EARLY PROTEINS; MUROMEGALOVIRUS; RATS; SALIVARY GLANDS; SEQUENCE DELETION; SPLEEN; TRANS-ACTIVATORS; VIRULENCE; VIRUS ACTIVATION; VIRUS LATENCY; VIRUS REPLICATION;

ANIMALIA; MURID HERPESVIRUS 2;

EID: 76849106105     PISSN: 00221317     EISSN: 14652099     Source Type: Journal    
DOI: 10.1099/vir.0.016022-0     Document Type: Article

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