The long-chain fatty acid receptor, GPR40, and glucolipotoxicity: Investigations using GPR40-knockout mice

Biochemical Society Transactions

Volumn 36, Issue 5, 2008, Pages 950-954

  Brownlie, Ruth ^a   Mayers, Rachel M ^a   Pierce, Jackie A ^a   Marley, Anna E ^a   Smith, David M ^a  

^a ASTRAZENECA   (United Kingdom)

Author keywords

cell; Fatty acid; G protein coupled receptor 40 (GPR40); Glucolipotoxicity; Islet of Langerhans

Indexed keywords

ANT 203; ANTIDIABETIC AGENT; G PROTEIN COUPLED RECEPTOR; G PROTEIN COUPLED RECEPTOR 40 AGONIST; G PROTEIN COUPLED RECEPTOR 40 ANTAGONIST; GLUCOSE; GW 1100; GW 9508; INSULIN; OLEIC ACID; PALMITIC ACID; PHOSPHOLIPASE C; SMALL INTERFERING RNA; TRIACYLGLYCEROL; UNCLASSIFIED DRUG;

APOPTOSIS; CONFERENCE PAPER; DRUG MECHANISM; FATTY LIVER; GENE OVEREXPRESSION; GLUCAGON RELEASE; GLUCOSE BLOOD LEVEL; GLUCOSE METABOLISM; HUMAN; INSULIN BLOOD LEVEL; INSULIN RELEASE; INSULIN SENSITIVITY; KNOCKOUT MOUSE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PANCREAS ISLET BETA CELL; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; TRANSGENIC MOUSE; TRIACYLGLYCEROL BLOOD LEVEL;

ANIMALS; DIETARY FATS; FATTY ACIDS; GLUCOSE; GLUCOSE TOLERANCE TEST; MICE; MICE, KNOCKOUT; RECEPTORS, G-PROTEIN-COUPLED;

ANIMALIA; MUS;

EID: 53849146735     PISSN: 03005127     EISSN: None     Source Type: Journal    
DOI: 10.1042/BST0360950     Document Type: Conference Paper

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