AML1-ETO driven acute leukemia: Insights into pathogenesis and potential therapeutic approaches

Frontiers of Medicine in China

Volumn 6, Issue 3, 2012, Pages 248-262

  Hatlen, Megan A ^a,b   Wang, Lan ^a   Nimer, Stephen D ^a,b  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^b WEILL CORNELL MEDICAL COLLEGE   (United States)

Author keywords

AML1 ETO; CD34+; hematopoiesis; Kasumi 1; leukemia; mouse model; mutation; pathway hits; t(8; 21)

Indexed keywords

AML1 ETO FUSION PROTEIN, HUMAN; AML1-ETO FUSION PROTEIN, HUMAN; ONCOPROTEIN; RUNX1 PROTEIN, MOUSE; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR RUNX1; TUMOR MARKER;

ACUTE GRANULOCYTIC LEUKEMIA; ANIMAL; CELL TRANSFORMATION; CHROMOSOME 21; CHROMOSOME 8; DISEASE MODEL; GENE EXPRESSION REGULATION; GENE TRANSLOCATION; GENETICS; GENOTYPE; HUMAN; MOUSE; PHENOTYPE; REVIEW; TRANSGENIC MOUSE;

ANIMALS; CELL TRANSFORMATION, NEOPLASTIC; CHROMOSOMES, HUMAN, PAIR 21; CHROMOSOMES, HUMAN, PAIR 8; CORE BINDING FACTOR ALPHA 2 SUBUNIT; DISEASE MODELS, ANIMAL; GENE EXPRESSION REGULATION, LEUKEMIC; GENOTYPE; HUMANS; LEUKEMIA, MYELOID, ACUTE; MICE; MICE, TRANSGENIC; ONCOGENE PROTEINS, FUSION; PHENOTYPE; TRANSCRIPTION FACTORS; TRANSLOCATION, GENETIC; TUMOR MARKERS, BIOLOGICAL;

EID: 84866128942     PISSN: 16737342     EISSN: 16737458     Source Type: Journal    
DOI: 10.1007/s11684-012-0206-6     Document Type: Review

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