메뉴 건너뛰기




Volumn 39, Issue 4 SUPPL. 3, 2002, Pages 6-11

Molecular genetics of human leukemias: New insights into therapy

Author keywords

[No Author keywords available]

Indexed keywords

FLT3 LIGAND; PROTEIN TYROSINE KINASE; STEM CELL FACTOR; TYROSINE KINASE RECEPTOR;

EID: 0036814971     PISSN: 00371963     EISSN: None     Source Type: Journal    
DOI: 10.1053/shem.2002.36921     Document Type: Article
Times cited : (174)

References (45)
  • 1
    • 0034696627 scopus 로고    scopus 로고
    • Role of the transcription factor AML-1 in acute leukemia and hematopoietic differentiation
    • Lutterbach B, Hiebert SW: Role of the transcription factor AML-1 in acute leukemia and hematopoietic differentiation. Gene 245:223-235, 2000
    • (2000) Gene , vol.245 , pp. 223-235
    • Lutterbach, B.1    Hiebert, S.W.2
  • 2
    • 0035962636 scopus 로고    scopus 로고
    • Transcription therapy for cancer
    • Pandolfi PP: Transcription therapy for cancer. Oncogene 20:3116-3127, 2001
    • (2001) Oncogene , vol.20 , pp. 3116-3127
    • Pandolfi, P.P.1
  • 3
    • 0035839922 scopus 로고    scopus 로고
    • Common themes in the pathogenesis of acute myeloid leukemia
    • Alcalay M, Orleth A, Sebastiani C, et al: Common themes in the pathogenesis of acute myeloid leukemia. Oncogene 20:5680-5694, 2001
    • (2001) Oncogene , vol.20 , pp. 5680-5694
    • Alcalay, M.1    Orleth, A.2    Sebastiani, C.3
  • 4
    • 0001933779 scopus 로고    scopus 로고
    • Chronic myelogenous leukemia
    • DeVita VT Jr, Hellman S, Rosenberg SA (eds): Philadelphia, PA, Lippincott, Williams & Wilkins
    • Kantarjian HM, Faderl S, Talpaz M: Chronic myelogenous leukemia, in DeVita VT Jr, Hellman S, Rosenberg SA (eds): Cancer: Principles and Practice of Oncology (Ed 6). Philadelphia, PA, Lippincott, Williams & Wilkins, 2001, pp 2433-2465
    • (2001) Cancer: Principles and Practice of Oncology (Ed 6) , pp. 2433-2465
    • Kantarjian, H.M.1    Faderl, S.2    Talpaz, M.3
  • 6
    • 0033529599 scopus 로고    scopus 로고
    • Transforming properties of the Huntingtin interacting protein 1/platelet-derived growth factor β receptor fusion protein
    • Ross TS, Gilliland DG: Transforming properties of the Huntingtin interacting protein 1/platelet-derived growth factor β receptor fusion protein. J Biol Chem 274:22328-22336, 1999
    • (1999) J Biol Chem , vol.274 , pp. 22328-22336
    • Ross, T.S.1    Gilliland, D.G.2
  • 7
    • 0028224348 scopus 로고
    • Fusion of PDGF receptor β to a novel ets-like gene, tel, in chronic myelomonocytic leukemia with t(5;12) chromosomal translocation
    • Golub TR, Barker GF, Lovett M, et al: Fusion of PDGF receptor β to a novel ets-like gene, tel, in chronic myelomonocytic leukemia with t(5;12) chromosomal translocation. Cell 77:307-316, 1994
    • (1994) Cell , vol.77 , pp. 307-316
    • Golub, T.R.1    Barker, G.F.2    Lovett, M.3
  • 8
    • 0029898682 scopus 로고    scopus 로고
    • Oligomerization of the ABL tyrosine kinase by the Ets protein TEL in human leukemia
    • Golub TR, Goga A, Barker GF, et al: Oligomerization of the ABL tyrosine kinase by the Ets protein TEL in human leukemia. Mol Cell Biol 16:4107-4116, 1996
    • (1996) Mol Cell Biol , vol.16 , pp. 4107-4116
    • Golub, T.R.1    Goga, A.2    Barker, G.F.3
  • 9
    • 0034678609 scopus 로고    scopus 로고
    • Signal transduction and transforming properties of the TEL-TRKC fusions associated with t(12;15)(p13;q25) in congenital fibrosarcoma and acute myelogenous leukemia
    • Liu Q, Schwaller J, Kutok J, et al: Signal transduction and transforming properties of the TEL-TRKC fusions associated with t(12;15)(p13;q25) in congenital fibrosarcoma and acute myelogenous leukemia. EMBO J 19:1827-1838, 2000
    • (2000) EMBO J , vol.19 , pp. 1827-1838
    • Liu, Q.1    Schwaller, J.2    Kutok, J.3
  • 10
    • 0031864246 scopus 로고    scopus 로고
    • Fusion of Huntingtin interacting protein 1 to platelet-derived growth factor β receptor (PDGFβR) in chronic myelomonocytic leukemia with t(5;7)(q33;q11.2)
    • Ross TS, Bernard OA, Berger R, et al: Fusion of Huntingtin interacting protein 1 to platelet-derived growth factor β receptor (PDGFβR) in chronic myelomonocytic leukemia with t(5;7)(q33;q11.2). Blood 91:4419-4426, 1998
    • (1998) Blood , vol.91 , pp. 4419-4426
    • Ross, T.S.1    Bernard, O.A.2    Berger, R.3
  • 11
    • 0033639119 scopus 로고    scopus 로고
    • Stat5 is essential for the myelo- and lymphoproliferative disease induced by TEL/JAK 2
    • Schwaller J, Parganas, E, Wang D, et al: Stat5 is essential for the myelo- and lymphoproliferative disease induced by TEL/JAK2. Mol Cell 6:693-704, 2000
    • (2000) Mol Cell , vol.6 , pp. 693-704
    • Schwaller, J.1    Parganas, E.2    Wang, D.3
  • 12
    • 0033999917 scopus 로고    scopus 로고
    • Fatal myeloproliferation, induced in mice by TEL/PDGFβR expression, depends on PDGFβR tyrosines 579/581
    • Tomasson MH, Sternberg DW, Williams IR, et al: Fatal myeloproliferation, induced in mice by TEL/PDGFβR expression, depends on PDGFβR tyrosines 579/581. J Clin Invest 105:423-432, 2000
    • (2000) J Clin Invest , vol.105 , pp. 423-432
    • Tomasson, M.H.1    Sternberg, D.W.2    Williams, I.R.3
  • 13
    • 0001225197 scopus 로고    scopus 로고
    • Acute leukemias
    • DeVita VT Jr, Hellman S, Rosenberg SA (eds): Philadelphia, PA, Lippincott Williams & Wilkins
    • Scheinberg DA, Maslak P, Weiss M: Acute leukemias, in DeVita VT Jr, Hellman S, Rosenberg SA (eds): Cancer: Principles and Practice of Oncology (Ed 6). Philadelphia, PA, Lippincott Williams & Wilkins, 2001, pp 2404-2433
    • (2001) Cancer: Principles and Practice of Oncology (Ed 6) , pp. 2404-2433
    • Scheinberg, D.A.1    Maslak, P.2    Weiss, M.3
  • 14
    • 16144362555 scopus 로고    scopus 로고
    • Failure of embryonic hematopoiesis and lethal hemorrhages in mouse embryos heterozygous for a knocked-in leukemia gene CBFB-MYH 11
    • Castilla LH, Wijmenga C, Wang Q, et al: Failure of embryonic hematopoiesis and lethal hemorrhages in mouse embryos heterozygous for a knocked-in leukemia gene CBFB-MYH11. Cell 87:687-696, 1996
    • (1996) Cell , vol.87 , pp. 687-696
    • Castilla, L.H.1    Wijmenga, C.2    Wang, Q.3
  • 15
    • 0030061554 scopus 로고    scopus 로고
    • AML1, the target of multiple chromosomal translocations in human leukemia, is essential for normal fetal liver hematopoiesis
    • Okuda T, van Deursen J, Hiebert SW, et al: AML1, the target of multiple chromosomal translocations in human leukemia, is essential for normal fetal liver hematopoiesis. Cell 84:321-330, 1996
    • (1996) Cell , vol.84 , pp. 321-330
    • Okuda, T.1    Van Deursen, J.2    Hiebert, S.W.3
  • 16
    • 0031025416 scopus 로고    scopus 로고
    • Embryonic lethality and impairment of haematopoiesis in mice heterozygous for an AML1-ETO fusion gene
    • Yergeau DA, Hetherington CJ, Wang Q, et al: Embryonic lethality and impairment of haematopoiesis in mice heterozygous for an AML1-ETO fusion gene. Nat Genet 15:303-306, 1997
    • (1997) Nat Genet , vol.15 , pp. 303-306
    • Yergeau, D.A.1    Hetherington, C.J.2    Wang, Q.3
  • 17
    • 0029004541 scopus 로고
    • Fusion of the TEL gene on 12p13 to the AML1 gene on 21q22 in acute lymphoblastic leukemia
    • Golub TR, Barker GF, Bohlander SK, et al: Fusion of the TEL gene on 12p13 to the AML1 gene on 21q22 in acute lymphoblastic leukemia. Proc Natl Acad Sci USA 92:4917-4921, 1995
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 4917-4921
    • Golub, T.R.1    Barker, G.F.2    Bohlander, S.K.3
  • 18
    • 0028925282 scopus 로고
    • The t(8;21) fusion protein interferes with AML-1B-dependent transcriptional activation
    • Meyers S, Lenny N, Hiebert SW: The t(8;21) fusion protein interferes with AML-1B-dependent transcriptional activation. Mol Cell Biol 15:1974-1982, 1995
    • (1995) Mol Cell Biol , vol.15 , pp. 1974-1982
    • Meyers, S.1    Lenny, N.2    Hiebert, S.W.3
  • 19
    • 9044231364 scopus 로고    scopus 로고
    • The t(12;21) translocation converts AML-1B from an activator to a repressor of transcription
    • Hiebert SW, Sun W, Davis JN, et al: The t(12;21) translocation converts AML-1B from an activator to a repressor of transcription. Mol Cell Biol 16:1349-1355, 1996
    • (1996) Mol Cell Biol , vol.16 , pp. 1349-1355
    • Hiebert, S.W.1    Sun, W.2    Davis, J.N.3
  • 20
    • 0031724804 scopus 로고    scopus 로고
    • ETO, a target of t(8;21) in acute leukemia, interacts with the N-CoR and mSin 3 corepressors
    • Lutterbach B, Westendorf JJ, Linggi B, et al: ETO, a target of t(8;21) in acute leukemia, interacts with the N-CoR and mSin3 corepressors. Mol Cell Biol 18:7176-7184, 1998
    • (1998) Mol Cell Biol , vol.18 , pp. 7176-7184
    • Lutterbach, B.1    Westendorf, J.J.2    Linggi, B.3
  • 21
    • 0032878921 scopus 로고    scopus 로고
    • The fusion gene Cbfb-MYH 11 blocks myeloid differentiation and predisposes mice to acute myelomonocytic leukaemia
    • Castilla LH, Garrett L, Adya N, et al: The fusion gene Cbfb-MYH11 blocks myeloid differentiation and predisposes mice to acute myelomonocytic leukaemia. Nat Genet 23:144-146, 1999
    • (1999) Nat Genet , vol.23 , pp. 144-146
    • Castilla, L.H.1    Garrett, L.2    Adya, N.3
  • 22
    • 0032873462 scopus 로고    scopus 로고
    • Both TEL and AML-1 contribute repression domains to the t(12;21) fusion protein
    • Fenrick R, Amann JM, Lutterbach B, et al: Both TEL and AML-1 contribute repression domains to the t(12;21) fusion protein. Mol Cell Biol 19:6566-6574, 1999
    • (1999) Mol Cell Biol , vol.19 , pp. 6566-6574
    • Fenrick, R.1    Amann, J.M.2    Lutterbach, B.3
  • 23
    • 0033118155 scopus 로고    scopus 로고
    • Core-binding factor: A central player in hematopoiesis and leukemia
    • Speck NA, Stacy T, Wang Q, et al: Core-binding factor: A central player in hematopoiesis and leukemia. Cancer Res 59:1789s-1793s, 1999 (suppl)
    • (1999) Cancer Res , vol.59 , Issue.SUPPL.
    • Speck, N.A.1    Stacy, T.2    Wang, Q.3
  • 24
    • 0036463950 scopus 로고    scopus 로고
    • Expression of a conditional AML1-ETO oncogene bypasses embryonic lethality and establishes a murine model of human t (8;21) acute myeloid leukemia
    • Higuchi M, O'Brien D, Kumaravelu P, et al. Expression of a conditional AML1-ETO oncogene bypasses embryonic lethality and establishes a murine model of human t (8;21) acute myeloid leukemia. Cancer Cell 1:63-74, 2002
    • (2002) Cancer Cell , vol.1 , pp. 63-74
    • Higuchi, M.1    O'Brien, D.2    Kumaravelu, P.3
  • 25
    • 0027276927 scopus 로고
    • In utero rearrangements in the trithorax-related oncogene in infant leukaemias
    • Ford AM, Ridge SA, Cabrera ME, et al: In utero rearrangements in the trithorax-related oncogene in infant leukaemias. Nature 363:358-360, 1993
    • (1993) Nature , vol.363 , pp. 358-360
    • Ford, A.M.1    Ridge, S.A.2    Cabrera, M.E.3
  • 26
    • 0009886478 scopus 로고
    • Clonal, nonconstitutional rearrangements of the MLL gene in infant twins with acute lymphoblastic leukemia: In utero chromosome rearrangement of 11q23
    • Gill Super HJ, Rothberg PG, Kobayashi H, et al: Clonal, nonconstitutional rearrangements of the MLL gene in infant twins with acute lymphoblastic leukemia: In utero chromosome rearrangement of 11q23. Blood 83:641-644, 1994
    • (1994) Blood , vol.83 , pp. 641-644
    • Gill Super, H.J.1    Rothberg, P.G.2    Kobayashi, H.3
  • 27
    • 11544323440 scopus 로고    scopus 로고
    • t(11;22)(q23; q11.2) in acute myeloid leukemia of infant twins fuses MLL with hCDCrel, a cell division cycle gene in the genomic region of deletion in DiGeorge and velocardiofacial syndromes
    • Megonigal MD, Rappaport EF, Jones DH, et al: t(11;22)(q23; q11.2) in acute myeloid leukemia of infant twins fuses MLL with hCDCrel, a cell division cycle gene in the genomic region of deletion in DiGeorge and velocardiofacial syndromes. Proc Natl Acad Sci USA 95:6413-6418, 1998
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 6413-6418
    • Megonigal, M.D.1    Rappaport, E.F.2    Jones, D.H.3
  • 28
    • 0033178875 scopus 로고    scopus 로고
    • Protracted and variable latency of acute lymphoblastic leukemia after TEL-AML 1 gene fusion in utero
    • Wiemels JL, Ford AM, Van Wering ER, et al: Protracted and variable latency of acute lymphoblastic leukemia after TEL-AML1 gene fusion in utero. Blood 94:1057-1062, 1999
    • (1999) Blood , vol.94 , pp. 1057-1062
    • Wiemels, J.L.1    Ford, A.M.2    Van Wering, E.R.3
  • 29
    • 0032830638 scopus 로고    scopus 로고
    • Haploinsufficiency of CBFA 2 causes familial thrombocytopenia with propensity to develop acute myelogenous leukaemia
    • Song W-J, Sullivan MG, Legare RD, et al: Haploinsufficiency of CBFA2 causes familial thrombocytopenia with propensity to develop acute myelogenous leukaemia. Nat Genet 23:166-175, 1999
    • (1999) Nat Genet , vol.23 , pp. 166-175
    • Song, W.-J.1    Sullivan, M.G.2    Legare, R.D.3
  • 30
    • 0033559746 scopus 로고    scopus 로고
    • Biallelic and heterozygous point mutations in the runt domain of the AML1/PEBP2αB gene associated with myeloblastic leukemias
    • Osato M, Asou N, Abdalla E, et al: Biallelic and heterozygous point mutations in the runt domain of the AML1/PEBP2αB gene associated with myeloblastic leukemias. Blood 93:1817-1824, 1999
    • (1999) Blood , vol.93 , pp. 1817-1824
    • Osato, M.1    Asou, N.2    Abdalla, E.3
  • 31
    • 0034667690 scopus 로고    scopus 로고
    • High incidence of biallelic point mutations in the runt domain of AML1/PEBP2αB gene in Mo acute myeloid leukemia and in myeloid malignancies with acquired trisomy 21
    • Preudhomme C, Warot-Loze D, Roumier C, et al: High incidence of biallelic point mutations in the runt domain of AML1/PEBP2αB gene in Mo acute myeloid leukemia and in myeloid malignancies with acquired trisomy 21. Blood 96:2862-2869, 2000
    • (2000) Blood , vol.96 , pp. 2862-2869
    • Preudhomme, C.1    Warot-Loze, D.2    Roumier, C.3
  • 32
    • 85112371432 scopus 로고    scopus 로고
    • Somatic mutations of the AML-1 gene are frequent in acute myeloid leukemia with FAB MO morphology
    • abstr 389
    • Yeoh AEJ, Williams K, Behm F, et al: Somatic mutations of the AML-1 gene are frequent in acute myeloid leukemia with FAB MO morphology. Blood 96:91a, 2000 (suppl 1, abstr 389)
    • (2000) Blood , vol.96 , Issue.SUPPL. 1
    • Yeoh, A.E.J.1    Williams, K.2    Behm, F.3
  • 33
    • 0034332068 scopus 로고    scopus 로고
    • Mutations of the AML 1 gene in myelodysplastic syndrome and their functional implications in leukemogenesis
    • Imai Y, Kurokawa M, Izutsu K, et al: Mutations of the AML1 gene in myelodysplastic syndrome and their functional implications in leukemogenesis. Blood 96:3154-3160, 2000
    • (2000) Blood , vol.96 , pp. 3154-3160
    • Imai, Y.1    Kurokawa, M.2    Izutsu, K.3
  • 34
    • 0035093813 scopus 로고    scopus 로고
    • Dominant-negative mutations of CEBPA, encoding CCAAT/enhancer binding protein-α (C/EBPα), in acute myeloid leukemia
    • Pabst T, Mueller BU, Zhang P, et al: Dominant-negative mutations of CEBPA, encoding CCAAT/enhancer binding protein-α (C/EBPα), in acute myeloid leukemia. Nat Genet 27:263-270, 2001
    • (2001) Nat Genet , vol.27 , pp. 263-270
    • Pabst, T.1    Mueller, B.U.2    Zhang, P.3
  • 35
    • 0033758958 scopus 로고    scopus 로고
    • FLT3 internal tandem duplication mutations in adult acute myeloid leukaemia define a high-risk group
    • Abu-Duhier FM, Goodeve AC, Wilson GA, et al: FLT3 internal tandem duplication mutations in adult acute myeloid leukaemia define a high-risk group. Br J Haematol 111:190-195, 2000
    • (2000) Br J Haematol , vol.111 , pp. 190-195
    • Abu-Duhier, F.M.1    Goodeve, A.C.2    Wilson, G.A.3
  • 36
    • 0034598830 scopus 로고    scopus 로고
    • Tandem-duplicated Flt3 constitutively activates STAT5 and MAP kinase and introduces autonomous cell growth in IL-3-dependent cell lines
    • Hayakawa F, Towatari M, Kiyoi H, et al: Tandem-duplicated Flt3 constitutively activates STAT5 and MAP kinase and introduces autonomous cell growth in IL-3-dependent cell lines. Oncogene 19:624-631, 2000
    • (2000) Oncogene , vol.19 , pp. 624-631
    • Hayakawa, F.1    Towatari, M.2    Kiyoi, H.3
  • 37
    • 0034554796 scopus 로고    scopus 로고
    • Flt 3 mutations from patients with acute myeloid leukemia induce transformation of 32D cells mediated by the Ras and STAT5 pathways
    • Mizuki M, Fenski R, Halfter H, et al: Flt3 mutations from patients with acute myeloid leukemia induce transformation of 32D cells mediated by the Ras and STAT5 pathways. Blood 96:3907-3914, 2000
    • (2000) Blood , vol.96 , pp. 3907-3914
    • Mizuki, M.1    Fenski, R.2    Halfter, H.3
  • 38
    • 0000117333 scopus 로고    scopus 로고
    • FLT3 length mutations in AML: Correlation to cytogenetics, FAB-subtype, and prognosis in 652 patients
    • abstr 3569
    • Schnittger S, Schoch C, Kern W, et al: FLT3 length mutations in AML: Correlation to cytogenetics, FAB-subtype, and prognosis in 652 patients. Blood 96:826a, 2000 (suppl 1, abstr 3569)
    • (2000) Blood , vol.96 , Issue.SUPPL. 1
    • Schnittger, S.1    Schoch, C.2    Kern, W.3
  • 39
    • 0035885955 scopus 로고    scopus 로고
    • The presence of a FLT3 internal tandem duplication in patients with acute myeloid leukemia (AML) adds important prognostic information to cytogenetic risk group and response to the first cycle of chemotherapy: Analysis of 854 patients from the United Kingdom Medical Research Council AML 10 and 12 trials
    • Kottaridis PD, Gale RE, Frew ME, et al: The presence of a FLT3 internal tandem duplication in patients with acute myeloid leukemia (AML) adds important prognostic information to cytogenetic risk group and response to the first cycle of chemotherapy: Analysis of 854 patients from the United Kingdom Medical Research Council AML 10 and 12 trials. Blood 98:1752-1759, 2001
    • (2001) Blood , vol.98 , pp. 1752-1759
    • Kottaridis, P.D.1    Gale, R.E.2    Frew, M.E.3
  • 40
    • 0035383768 scopus 로고    scopus 로고
    • FLT3, RAS, and TP 53 mutations in elderly patients with acute myeloid leukemia
    • Stirewalt DL, Kopecky KJ, Meshinchi S, et al: FLT3, RAS, and TP53 mutations in elderly patients with acute myeloid leukemia. Blood 97:3589-3595, 2001
    • (2001) Blood , vol.97 , pp. 3589-3595
    • Stirewalt, D.L.1    Kopecky, K.J.2    Meshinchi, S.3
  • 42
    • 79960971001 scopus 로고    scopus 로고
    • BCR/ABL cooperates with NUP98/HOXA9 to cause CML blast crisis
    • abstr 493
    • Dash AB, Williams IR, Kutok JL, et al: BCR/ABL cooperates with NUP98/HOXA9 to cause CML blast crisis. Blood 98:117a-118a, 2001 (suppl 1, abstr 493)
    • (2001) Blood , vol.98 , Issue.SUPPL. 1
    • Dash, A.B.1    Williams, I.R.2    Kutok, J.L.3
  • 43
    • 0001338423 scopus 로고    scopus 로고
    • Phase II study of STI571, a tyrosine kinase inhibitor, in patients (pts) with resistant or refractory Philadelphia chromosome-positive chronic myeloid leukemia (ph+CML)
    • abstr 2022
    • Kantarjian H, Sawyers C, Hochhaus A, et al for the International STI571 Study Group: Phase II study of STI571, a tyrosine kinase inhibitor, in patients (pts) with resistant or refractory Philadelphia chromosome-positive chronic myeloid leukemia (ph+CML). Blood 96:470a, 2000 (suppl 1, abstr 2022)
    • (2000) Blood , vol.96 , Issue.SUPPL. 1
    • Kantarjian, H.1    Sawyers, C.2    Hochhaus, A.3
  • 44
    • 0000869570 scopus 로고    scopus 로고
    • A phase II study to determine the safety and anti-leukemic effects of ST1571 in patients with Philadelphia chromosome positive chronic myeloid leukemia in myeloid blast crisis
    • abstr 2165
    • Sawyers CL, Hochhaus A, Feldman E, et al: A phase II study to determine the safety and anti-leukemic effects of ST1571 in patients with Philadelphia chromosome positive chronic myeloid leukemia in myeloid blast crisis. Blood 96:503a, 2000 (abstr 2165)
    • (2000) Blood , vol.96
    • Sawyers, C.L.1    Hochhaus, A.2    Feldman, E.3
  • 45
    • 0001566710 scopus 로고    scopus 로고
    • A phase II study of STI571 in adult patients with Philadelphia chromosome positive chronic myeloid leukemia in accelerated phase
    • abstr 2021
    • Talpaz M, Silver RT, Druker BJ, et al: A phase II study of STI571 in adult patients with Philadelphia chromosome positive chronic myeloid leukemia in accelerated phase. Blood 96:469a, 2000 (suppl 1, abstr 2021)
    • (2000) Blood , vol.96 , Issue.SUPPL. 1
    • Talpaz, M.1    Silver, R.T.2    Druker, B.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.