Direct Behavioral Evidence for Retronasal Olfaction in Rats

PLoS ONE

Volumn 7, Issue 9, 2012, Pages

  Gautam, Shree Hari ^a,b   Verhagen, Justus V ^a,b  

^a JOHN B PIERCE LABORATORY   (United States)

^b YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PENTYL ACETATE; WATER;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; FEEDING BEHAVIOR; FEMALE; FLAVOR; LICKING; MENTAL TASK; NONHUMAN; OLFACTORY DISCRIMINATION; RAT; RETRONASAL OLFACTION; SMELLING;

ANIMALS; BEHAVIOR, ANIMAL; FEMALE; NASAL CAVITY; RATS; RATS, LONG-EVANS; SMELL;

ANIMALIA; RATTUS;

EID: 84866113449     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0044781     Document Type: Article

References (34)

1. Duffy VB, (2007) Variation in oral sensation: implications for diet and health. Current Opinion in Gastroenterology 23: 171-177.
2. Small DM, Prescott J, (2005) Odor/taste integration and the perception of flavor. Exp Br Res 166: 345-357.
3. Veldhuizen MG, Nachtigal D, Teulings L, Gitelman DR, Small DM (2010) The insular taste cortex contributes to odor quality coding. Frontiers in Human Neuroscience 4.
4. Rozin P, (1982) "Taste-smell confusions" and the duality of the olfactory sense. Percept & Psychophys 31: 397-401.
5. Murphy C, Cain WS, (1980) Taste and olfaction: independence vs interaction. Physiol & Behav 24: 601-605.
6. Murphy C, Cain WS, Bartoshuk LM, (1977) Mutual action of taste and olfaction. Sens Processes 1: 204-211.
7. M RO, G JI, M.H D (2000) Veterinary Clinical examination and Diagnosis.: W. B. Saunders, Philadelphia.
8. Negus VE (1927) The Function of the Epiglottis. J Anat 62 1-8.
9. Burdach KJ, Doty RL, (1987) The effects of mouth movements, swallowing, and spitting on retronasal odor perception. Physiol Behav 41: 353-356.
10. Bouton ME, Jones DL, McPhillps SA, Swarzentruber D, (1986) Potentiation and overshadowing in odor-aversion learning: role of method of odor presentation, the distal-proximal cue distinction and the conditionability of odor. Learning & Motivation 17: 115-138.
11. Slotnick BM, Westbrook F, Darling FMC, (1997) What the rat's nose tells the rat's mouth: long delay aversion conditioning with aqueous odors and potentiation of taste by odors. Animal Learning & Behav 25: 357-369.
12. Inui T, Shimura T, Yamamoto T, (2006) Effects of brain lesions on taste-potentiated odor aversion in rats. Behav Neurosci 120: 590-599.
13. Gautam SH, Verhagen JV, (2010) Evidence that the Sweetness of Odors Depends on Experience in Rats. Chemical Senses 35: 767-776.
14. Gautam SH, Verhagen JV, (2009) Rat as a Model for the Study of Multimodal Integration of Flavor. Chemical Senses 34: A43-A43.
15. Zhao K, Scherer PW, Hajiloo SA, Dalton P, (2004) Effect of anatomy on human nasal air flow and odor transport pattern:implications for olfaction. Chem Senses 29: 365-379.
16. Zhao K, Dalton P, Yang GC, Scherer PW, (2006) Numerical modeling of turbulent and laminar airflow and odorant transport during sniffing in the human and rat nose. Chem Senses 31: 107-118.
17. Scott JW, Acevedo HP, Sherrill L, Phan M, (2007) Responses of the rat olfactory epithelium to retronasal air flow. J Neurophys 97: 1941-1950.
18. Verhagen JV, Wesson DW, Netoff TI, White JA, Wachowiak M, (2007) Sniffing controls an adaptive filter of sensory input to the olfactory bulb. Nature Neuroscience 10: 631-639.
19. Schoenbaum G, Garmon JW, Setlow B, (2001) A novel method for detecting licking behavior during recording of electrophysiological signals from the brain. J Neurosc Methods 106: 139-146.
20. Youngentob SL, Mozell MM, Sheehe PR, Hornung DE, (1987) A quantitative analysis of sniffing strategies in rats performing odor detection tasks. Physiol Behav 41: 59-69.
21. Heilmann S, Hummel T, (2004) A new method for comparing orthonasal and retronasal olfaction. Behav Neurosci 118: 412-419.
22. Pierce J, Halpern BP, (1996) Orthonasal and retronasal odorant identification based upon vapor phase input from common substances. Chem Senses 21: 529-543.
23. Small DM, Gerber JC, Mak YE, Hummel T, (2005) Differential neural responses evoked by orthonasal versus retronasal odorant perception in humans. Neuron 47: 593-605.
24. Sun BC, Halpern BP, (2005) Identification of air phase retronasal and orthonasal odorant pairs. Chem Senses 30: 693-706.
25. Frasnelli J, van Ruth S, Kriukova I, Hummel T, (2005) Intranasal Concentrations of Orally Administered Flavors. Chemical Senses 30: 575-582.
26. Scott-Johnson PE, Blakley D, Scott JW, (2000) Effects of air flow on rat electroolfactogram. Chem Senses 25: 761-768.
27. Mozell MM, Jagodowicz M, (1973) Chromatographic separation of odorants by the nose: retention times measured across in vivo olfactory mucosa. Science 181: 1247-1249.
28. Gautam SH, Verhagen JV, (2012) Retronasal odor representations in the dorsal olfactory bulb of rats. J Neurosci 32: 7949-7959.
29. Heath RB, Steffey EP, Thurmon JC, Wertz EM, Meagher DM, et al. (1989) Laryngotracheal lesions following routine orotracheal intubation in the horse. Equine Vet J 21: 434-437.
30. Holcombe SJ, (1998) Neuromuscular regulation of the larynx and nasopharynx in the horse. AAEP Proceedings 44: 26-29.
31. Rivera B, Miller S, Brown EN, Price R, (2005) A novel method for endotracheal intubation of mice and rats used in imaging studies. Contemp Top Lab Anim Sci 44: 52-55.
32. Miller MJ, Martin RJ, Carlo WA, Fouke JM, Strohl KP, et al. (1985) Oral breathing in newborn infants. J Pediatr 107: 465-469.
33. Sasaki CT, Levine PA, Laitman JT, Crelin ESJ, (1977) Postnatal descent of the epiglottis in man. A preliminary report. Arch Otolaryngol 103: 169-171.
34. Bergeson PS, Shaw JC, (2001) Are Infants Really Obligatory Nasal Breathers? Clinical Pediatrics 40: 567-569.