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Volumn 217, Issue 11, 2012, Pages 1097-1105

Targeted complement inhibition as a promising strategy for preventing inflammatory complications in hemodialysis

Author keywords

Complement; Hemodialysis; Inflammation; Innate immunity; Therapeutics

Indexed keywords

C REACTIVE PROTEIN; CLASSICAL COMPLEMENT PATHWAY C3 C5 CONVERTASE; COMPLEMENT COMPONENT C1Q; COMPLEMENT FACTOR H; COMPLEMENT INHIBITOR; ECULIZUMAB; INTERLEUKIN 6; PEPTIDOMIMETIC AGENT; PMX 53; POT 4; THROMBOPLASTIN; UNCLASSIFIED DRUG;

EID: 84866045427     PISSN: 01712985     EISSN: 18783279     Source Type: Journal    
DOI: 10.1016/j.imbio.2012.07.012     Document Type: Review
Times cited : (44)

References (135)
  • 2
  • 4
    • 84892591143 scopus 로고    scopus 로고
    • Alcon Research. Evaluation of AL-78898A in Exudative Age-Related Macular Degeneration (AMD). Source: ClinicalTrials.gov - NIH.
    • Alcon Research, 2012. Evaluation of AL-78898A in Exudative Age-Related Macular Degeneration (AMD). Source: ClinicalTrials.gov - NIH. http://clinicaltrials.gov/ct2/show/NCT01157065.
    • (2012)
  • 6
    • 30444458690 scopus 로고    scopus 로고
    • Surface-attached PEO in the form of activated Pluronic with immobilized factor H reduces both coagulation and complement activation in a whole-blood model
    • Andersson J., Bexborn F., Klinth J., Nilsson B., Ekdahl K.N. Surface-attached PEO in the form of activated Pluronic with immobilized factor H reduces both coagulation and complement activation in a whole-blood model. J. Biomed. Mater. Res. A 2006, 76:25-34.
    • (2006) J. Biomed. Mater. Res. A , vol.76 , pp. 25-34
    • Andersson, J.1    Bexborn, F.2    Klinth, J.3    Nilsson, B.4    Ekdahl, K.N.5
  • 7
    • 7444238105 scopus 로고    scopus 로고
    • Binding of C3 fragments on top of adsorbed plasma proteins during complement activation on a model biomaterial surface
    • Andersson J., Ekdahl K.N., Lambris J.D., Nilsson B. Binding of C3 fragments on top of adsorbed plasma proteins during complement activation on a model biomaterial surface. Biomaterials 2005, 26:1477-1485.
    • (2005) Biomaterials , vol.26 , pp. 1477-1485
    • Andersson, J.1    Ekdahl, K.N.2    Lambris, J.D.3    Nilsson, B.4
  • 8
    • 0036604084 scopus 로고    scopus 로고
    • C3 adsorbed to a polymer surface can form an initiating alternative pathway convertase
    • Andersson J., Ekdahl K.N., Larsson R., Nilsson U.R., Nilsson B. C3 adsorbed to a polymer surface can form an initiating alternative pathway convertase. J. Immunol. 2002, 168:5786-5791.
    • (2002) J. Immunol. , vol.168 , pp. 5786-5791
    • Andersson, J.1    Ekdahl, K.N.2    Larsson, R.3    Nilsson, U.R.4    Nilsson, B.5
  • 9
    • 0034918088 scopus 로고    scopus 로고
    • Binding of a model regulator of complement activation (RCA) to a biomaterial surface: surface-bound factor H inhibits complement activation
    • Andersson J., Larsson R., Richter R., Ekdahl K.N., Nilsson B. Binding of a model regulator of complement activation (RCA) to a biomaterial surface: surface-bound factor H inhibits complement activation. Biomaterials 2001, 22:2435-2443.
    • (2001) Biomaterials , vol.22 , pp. 2435-2443
    • Andersson, J.1    Larsson, R.2    Richter, R.3    Ekdahl, K.N.4    Nilsson, B.5
  • 10
    • 0347384110 scopus 로고    scopus 로고
    • Optimal heparin surface concentration and antithrombin binding capacity as evaluated with human non-anticoagulated blood in vitro
    • Andersson J., Sanchez J., Ekdahl K.N., Elgue G., Nilsson B., Larsson R. Optimal heparin surface concentration and antithrombin binding capacity as evaluated with human non-anticoagulated blood in vitro. J. Biomed. Mater. Res. A 2003, 67:458-466.
    • (2003) J. Biomed. Mater. Res. A , vol.67 , pp. 458-466
    • Andersson, J.1    Sanchez, J.2    Ekdahl, K.N.3    Elgue, G.4    Nilsson, B.5    Larsson, R.6
  • 11
    • 0023484114 scopus 로고
    • Non-enzymic glycation of individual plasma proteins in normoglycemic and hyperglycemic patients
    • Austin G.E., Mullins R.H., Morin L.G. Non-enzymic glycation of individual plasma proteins in normoglycemic and hyperglycemic patients. Clin. Chem. 1987, 33:2220-2224.
    • (1987) Clin. Chem. , vol.33 , pp. 2220-2224
    • Austin, G.E.1    Mullins, R.H.2    Morin, L.G.3
  • 12
    • 0032572913 scopus 로고    scopus 로고
    • The effects of normal as compared with low hematocrit values in patients with cardiac disease who are receiving hemodialysis and epoetin
    • Besarab A., Bolton W.K., Browne J.K., Egrie J.C., Nissenson A.R., Okamoto D.M., Schwab S.J., Goodkin D.A. The effects of normal as compared with low hematocrit values in patients with cardiac disease who are receiving hemodialysis and epoetin. N. Engl. J. Med. 1998, 339:584-590.
    • (1998) N. Engl. J. Med. , vol.339 , pp. 584-590
    • Besarab, A.1    Bolton, W.K.2    Browne, J.K.3    Egrie, J.C.4    Nissenson, A.R.5    Okamoto, D.M.6    Schwab, S.J.7    Goodkin, D.A.8
  • 14
    • 0037667047 scopus 로고    scopus 로고
    • Large-scale manufacture of peptide therapeutics by chemical synthesis
    • Bray B.L. Large-scale manufacture of peptide therapeutics by chemical synthesis. Nat. Rev. Drug Discov. 2003, 2:587-593.
    • (2003) Nat. Rev. Drug Discov. , vol.2 , pp. 587-593
    • Bray, B.L.1
  • 16
    • 0034056242 scopus 로고    scopus 로고
    • C1-Esterase inhibitor: an anti-inflammatory agent and its potential use in the treatment of diseases other than hereditary angioedema
    • Caliezi C., Wuillemin W.A., Zeerleder S., Redondo M., Eisele B., Hack C.E. C1-Esterase inhibitor: an anti-inflammatory agent and its potential use in the treatment of diseases other than hereditary angioedema. Pharmacol. Rev. 2000, 52:91-112.
    • (2000) Pharmacol. Rev. , vol.52 , pp. 91-112
    • Caliezi, C.1    Wuillemin, W.A.2    Zeerleder, S.3    Redondo, M.4    Eisele, B.5    Hack, C.E.6
  • 17
    • 0027955095 scopus 로고
    • Cuprophane but not synthetic membrane induces increases in serum tumor necrosis factor-alpha levels during hemodialysis
    • Canivet E., Lavaud S., Wong T., Guenounou M., Willemin J.C., Potron G., Chanard J. Cuprophane but not synthetic membrane induces increases in serum tumor necrosis factor-alpha levels during hemodialysis. Am. J. Kidney Dis. 1994, 23:41-46.
    • (1994) Am. J. Kidney Dis. , vol.23 , pp. 41-46
    • Canivet, E.1    Lavaud, S.2    Wong, T.3    Guenounou, M.4    Willemin, J.C.5    Potron, G.6    Chanard, J.7
  • 18
    • 34548505998 scopus 로고    scopus 로고
    • French Study Group for Nutrition in Dialysis Intradialytic parenteral nutrition does not improve survival in malnourished hemodialysis patients: a 2-year multicenter, prospective, randomized study
    • Cano N.J., Fouque D., Roth H., Aparicio M., Azar R., Canaud B., Chauveau P., Combe C., Laville M., Leverve X.M., French Study Group for Nutrition in Dialysis Intradialytic parenteral nutrition does not improve survival in malnourished hemodialysis patients: a 2-year multicenter, prospective, randomized study. J. Am. Soc. Nephrol. 2007, 18:2583-2591.
    • (2007) J. Am. Soc. Nephrol. , vol.18 , pp. 2583-2591
    • Cano, N.J.1    Fouque, D.2    Roth, H.3    Aparicio, M.4    Azar, R.5    Canaud, B.6    Chauveau, P.7    Combe, C.8    Laville, M.9    Leverve, X.M.10
  • 19
    • 0026569323 scopus 로고
    • Serum interleukin-6 in long-term hemodialyzed patients
    • Cavaillon J.M., Poignet J.L., Fitting C., Delons S. Serum interleukin-6 in long-term hemodialyzed patients. Nephron 1992, 60:307-313.
    • (1992) Nephron , vol.60 , pp. 307-313
    • Cavaillon, J.M.1    Poignet, J.L.2    Fitting, C.3    Delons, S.4
  • 22
    • 42549118771 scopus 로고    scopus 로고
    • The effect of glycation of CD59 on complement-mediated cytolysis
    • Cheng Y., Gao M. The effect of glycation of CD59 on complement-mediated cytolysis. Cell. Mol. Immunol. 2005, 2:313-317.
    • (2005) Cell. Mol. Immunol. , vol.2 , pp. 313-317
    • Cheng, Y.1    Gao, M.2
  • 23
    • 0021017726 scopus 로고
    • Anaphylatoxin formation during hemodialysis: effects of different dialyzer membranes
    • Chenoweth D.E., Cheung A.K., Henderson L.W. Anaphylatoxin formation during hemodialysis: effects of different dialyzer membranes. Kidney Int. 1983, 24:764-769.
    • (1983) Kidney Int. , vol.24 , pp. 764-769
    • Chenoweth, D.E.1    Cheung, A.K.2    Henderson, L.W.3
  • 24
    • 0025475337 scopus 로고
    • Biocompatibility of hemodialysis membranes
    • Cheung A.K. Biocompatibility of hemodialysis membranes. J. Am. Soc. Nephrol. 1990, 1:150-161.
    • (1990) J. Am. Soc. Nephrol. , vol.1 , pp. 150-161
    • Cheung, A.K.1
  • 25
    • 0024373534 scopus 로고
    • Activation of the alternative pathway of complement by cellulosic hemodialysis membranes
    • Cheung A.K., Parker C.J., Wilcox L., Janatova J. Activation of the alternative pathway of complement by cellulosic hemodialysis membranes. Kidney Int. 1989, 36:257-265.
    • (1989) Kidney Int. , vol.36 , pp. 257-265
    • Cheung, A.K.1    Parker, C.J.2    Wilcox, L.3    Janatova, J.4
  • 26
    • 79952118241 scopus 로고    scopus 로고
    • Suppression of drusen formation by compstatin, a peptide inhibitor of complement C3 activation, on cynomolgus monkey with early-onset macular degeneration
    • Chi Z.L., Yoshida T., Lambris J.D., Iwata T. Suppression of drusen formation by compstatin, a peptide inhibitor of complement C3 activation, on cynomolgus monkey with early-onset macular degeneration. Adv. Exp. Med. Biol. 2010, 703:127-135.
    • (2010) Adv. Exp. Med. Biol. , vol.703 , pp. 127-135
    • Chi, Z.L.1    Yoshida, T.2    Lambris, J.D.3    Iwata, T.4
  • 28
    • 0017413401 scopus 로고
    • Hemodialysis leukopenia. Pulmonary vascular leukostasis resulting from complement activation by dialyzer cellophane membranes
    • Craddock P.R., Fehr J., Dalmasso A.P., Brighan K.L., Jacob H.S. Hemodialysis leukopenia. Pulmonary vascular leukostasis resulting from complement activation by dialyzer cellophane membranes. J. Clin. Invest. 1977, 59:879-888.
    • (1977) J. Clin. Invest. , vol.59 , pp. 879-888
    • Craddock, P.R.1    Fehr, J.2    Dalmasso, A.P.3    Brighan, K.L.4    Jacob, H.S.5
  • 29
    • 78049421004 scopus 로고    scopus 로고
    • Unfractionated heparin for hemodialysis: still the best option
    • Cronin R.E., Reilly R.F. Unfractionated heparin for hemodialysis: still the best option. Semin. Dial. 2010, 23:510-515.
    • (2010) Semin. Dial. , vol.23 , pp. 510-515
    • Cronin, R.E.1    Reilly, R.F.2
  • 30
    • 80052270866 scopus 로고    scopus 로고
    • What are the anticoagulation options for intermittent hemodialysis?
    • Davenport A. What are the anticoagulation options for intermittent hemodialysis?. Nat. Rev. Nephrol. 2011, 7:499-508.
    • (2011) Nat. Rev. Nephrol. , vol.7 , pp. 499-508
    • Davenport, A.1
  • 31
    • 77953526220 scopus 로고    scopus 로고
    • Membrane designs and composition for hemodialysis, hemofiltration and hemodialfiltration: past, present and future
    • Davenport A. Membrane designs and composition for hemodialysis, hemofiltration and hemodialfiltration: past, present and future. Minerva Urol. Nefrol. 2010, 62:29-40.
    • (2010) Minerva Urol. Nefrol. , vol.62 , pp. 29-40
    • Davenport, A.1
  • 33
    • 13444271717 scopus 로고    scopus 로고
    • Glycation of CD59 impairs complement regulation on erythrocytes from diabetic subjects
    • Davies C.S., Harris C.L., Morgan B.P. Glycation of CD59 impairs complement regulation on erythrocytes from diabetic subjects. Immunology 2005, 114:280-286.
    • (2005) Immunology , vol.114 , pp. 280-286
    • Davies, C.S.1    Harris, C.L.2    Morgan, B.P.3
  • 34
    • 0142245455 scopus 로고    scopus 로고
    • Safety and efficacy of pasteurized C1 inhibitor concentrate (Berinert P) in hereditary angioedema: a review
    • De S.J., Groner A., Lindner J. Safety and efficacy of pasteurized C1 inhibitor concentrate (Berinert P) in hereditary angioedema: a review. Transfus. Apher. Sci. 2003, 29:247-254.
    • (2003) Transfus. Apher. Sci. , vol.29 , pp. 247-254
    • De, S.J.1    Groner, A.2    Lindner, J.3
  • 35
    • 0025055437 scopus 로고
    • Fluid phase generation of terminal complement complex as a novel index of bioincompatibility
    • Deppisch R., Schmitt V., Bommer J., Hansch G.M., Ritz E., Rauterberg E.W. Fluid phase generation of terminal complement complex as a novel index of bioincompatibility. Kidney Int. 1990, 37:696-706.
    • (1990) Kidney Int. , vol.37 , pp. 696-706
    • Deppisch, R.1    Schmitt, V.2    Bommer, J.3    Hansch, G.M.4    Ritz, E.5    Rauterberg, E.W.6
  • 37
    • 60849084562 scopus 로고    scopus 로고
    • Inhibition of complement activation on a model biomaterial surface by streptococcal M protein-derived peptides
    • Engberg A.E., Sandholm K., Bexborn F., Persson J., Nilsson B., Lindahl G., Ekdahl K.N. Inhibition of complement activation on a model biomaterial surface by streptococcal M protein-derived peptides. Biomaterials 2009, 30:2653-2659.
    • (2009) Biomaterials , vol.30 , pp. 2653-2659
    • Engberg, A.E.1    Sandholm, K.2    Bexborn, F.3    Persson, J.4    Nilsson, B.5    Lindahl, G.6    Ekdahl, K.N.7
  • 38
    • 0028215024 scopus 로고
    • Effect of hemodialysis on peripheral blood monocyte tumor necrosis factor-alpha, interleukin-6, and interleukin-8 secretion in vitro
    • Engelberts I., Francot G.J., Leunissen K.M., Haenen B., Ceska M., van der Linden C.J., Buurman W.A. Effect of hemodialysis on peripheral blood monocyte tumor necrosis factor-alpha, interleukin-6, and interleukin-8 secretion in vitro. Nephron 1994, 66:396-403.
    • (1994) Nephron , vol.66 , pp. 396-403
    • Engelberts, I.1    Francot, G.J.2    Leunissen, K.M.3    Haenen, B.4    Ceska, M.5    van der Linden, C.J.6    Buurman, W.A.7
  • 39
    • 0031700585 scopus 로고    scopus 로고
    • Adsorption of complement, cytokines, and proteins by different dialysis membrane materials: evaluation by confocal laser scanning fluorescence microscopy
    • Fujimori A., Naito H., Miyazaki T. Adsorption of complement, cytokines, and proteins by different dialysis membrane materials: evaluation by confocal laser scanning fluorescence microscopy. Artif. Organs 1998, 22:1014-1017.
    • (1998) Artif. Organs , vol.22 , pp. 1014-1017
    • Fujimori, A.1    Naito, H.2    Miyazaki, T.3
  • 40
    • 34548803964 scopus 로고    scopus 로고
    • Protein damage and inflammation in uraemia and dialysis patients
    • Galli F. Protein damage and inflammation in uraemia and dialysis patients. Nephrol. Dial. Transplant. 2007, 22(Suppl. 5):v20-v36.
    • (2007) Nephrol. Dial. Transplant. , vol.22 , Issue.SUPPL. 5
    • Galli, F.1
  • 41
    • 0033008725 scopus 로고    scopus 로고
    • Influence of dialysis with polyamide vs haemophan haemodialysers on monokines and complement activation during a 4-month long-term study
    • Girndt M., Heisel O., Kohler H. Influence of dialysis with polyamide vs haemophan haemodialysers on monokines and complement activation during a 4-month long-term study. Nephrol. Dial. Transplant. 1999, 14:676-682.
    • (1999) Nephrol. Dial. Transplant. , vol.14 , pp. 676-682
    • Girndt, M.1    Heisel, O.2    Kohler, H.3
  • 45
    • 0027254912 scopus 로고
    • Clinical implications of hemodialysis membrane biocompatibility
    • Hakim R.M. Clinical implications of hemodialysis membrane biocompatibility. Kidney Int. 1993, 44:484-494.
    • (1993) Kidney Int. , vol.44 , pp. 484-494
    • Hakim, R.M.1
  • 46
    • 0025025311 scopus 로고
    • Increase of C-reactive protein serum values following haemodialysis
    • Haubitz M., Schulze M., Koch K.M. Increase of C-reactive protein serum values following haemodialysis. Nephrol. Dial. Transplant. 1990, 5:500-503.
    • (1990) Nephrol. Dial. Transplant. , vol.5 , pp. 500-503
    • Haubitz, M.1    Schulze, M.2    Koch, K.M.3
  • 47
    • 58149237156 scopus 로고    scopus 로고
    • The Staphylococcus aureus protein Sbi acts as a complement inhibitor and forms a tripartite complex with host complement Factor H and C3b
    • Haupt K., Reuter M., van den E.J., Burman J., Halbich S., Richter J., Skerka C., Zipfel P.F. The Staphylococcus aureus protein Sbi acts as a complement inhibitor and forms a tripartite complex with host complement Factor H and C3b. PLoS Pathog. 2008, 4:e1000250.
    • (2008) PLoS Pathog. , vol.4
    • Haupt, K.1    Reuter, M.2    van den, E.J.3    Burman, J.4    Halbich, S.5    Richter, J.6    Skerka, C.7    Zipfel, P.F.8
  • 48
    • 0025250684 scopus 로고
    • Generation of the membrane attack complex during haemodialysis: impact of classical and alternative pathway components
    • Hauser A.C., Derfler K., Stockenhuber F., Janata O., Balcke P. Generation of the membrane attack complex during haemodialysis: impact of classical and alternative pathway components. Clin. Sci. (Lond) 1990, 79:471-476.
    • (1990) Clin. Sci. (Lond) , vol.79 , pp. 471-476
    • Hauser, A.C.1    Derfler, K.2    Stockenhuber, F.3    Janata, O.4    Balcke, P.5
  • 49
    • 0025169936 scopus 로고
    • Influence of uremia and hemodialysis on circulating interleukin-1 and tumor necrosis factor alpha
    • Herbelin A., Nguyen A.T., Zingraff J., Urena P., Descamps-Latscha B. Influence of uremia and hemodialysis on circulating interleukin-1 and tumor necrosis factor alpha. Kidney Int. 1990, 37:116-125.
    • (1990) Kidney Int. , vol.37 , pp. 116-125
    • Herbelin, A.1    Nguyen, A.T.2    Zingraff, J.3    Urena, P.4    Descamps-Latscha, B.5
  • 50
    • 0025801687 scopus 로고
    • Elevated circulating levels of interleukin-6 in patients with chronic renal failure
    • Herbelin A., Urena P., Nguyen A.T., Zingraff J., Descamps-Latscha B. Elevated circulating levels of interleukin-6 in patients with chronic renal failure. Kidney Int. 1991, 39:954-960.
    • (1991) Kidney Int. , vol.39 , pp. 954-960
    • Herbelin, A.1    Urena, P.2    Nguyen, A.T.3    Zingraff, J.4    Descamps-Latscha, B.5
  • 51
    • 84861875420 scopus 로고    scopus 로고
    • Complement C5a: impact on the field of veterinary medicine
    • Hezmee M.N., Shiels I.A., Rolfe B.E., Mills P.C. Complement C5a: impact on the field of veterinary medicine. Vet. J. 2012, 192:264-271.
    • (2012) Vet. J. , vol.192 , pp. 264-271
    • Hezmee, M.N.1    Shiels, I.A.2    Rolfe, B.E.3    Mills, P.C.4
  • 55
    • 34548566329 scopus 로고    scopus 로고
    • Effect of homocysteine lowering on mortality and vascular disease in advanced chronic kidney disease and end-stage renal disease: a randomized controlled trial
    • Jamison R.L., Hartigan P., Kaufman J.S., Goldfarb D.S., Warren S.R., Guarino P.D., Gaziano J.M., Veterans A.S.I. Effect of homocysteine lowering on mortality and vascular disease in advanced chronic kidney disease and end-stage renal disease: a randomized controlled trial. J. Am. Med. Assoc. 2007, 298:1163-1170.
    • (2007) J. Am. Med. Assoc. , vol.298 , pp. 1163-1170
    • Jamison, R.L.1    Hartigan, P.2    Kaufman, J.S.3    Goldfarb, D.S.4    Warren, S.R.5    Guarino, P.D.6    Gaziano, J.M.7    Veterans, A.S.I.8
  • 56
    • 35748951604 scopus 로고    scopus 로고
    • Structure of compstatin in complex with complement component C3c reveals a new mechanism of complement inhibition
    • Janssen B.J., Halff E.F., Lambris J.D., Gros P. Structure of compstatin in complex with complement component C3c reveals a new mechanism of complement inhibition. J. Biol. Chem. 2007, 282:29241-29247.
    • (2007) J. Biol. Chem. , vol.282 , pp. 29241-29247
    • Janssen, B.J.1    Halff, E.F.2    Lambris, J.D.3    Gros, P.4
  • 57
    • 33645650398 scopus 로고    scopus 로고
    • Human C4b-binding protein, structural basis for interaction with streptococcal M protein, a major bacterial virulence factor
    • Jenkins H.T., Mark L., Ball G., Persson J., Lindahl G., Uhrin D., Blom A.M., Barlow P.N. Human C4b-binding protein, structural basis for interaction with streptococcal M protein, a major bacterial virulence factor. J. Biol. Chem. 2006, 281:3690-3697.
    • (2006) J. Biol. Chem. , vol.281 , pp. 3690-3697
    • Jenkins, H.T.1    Mark, L.2    Ball, G.3    Persson, J.4    Lindahl, G.5    Uhrin, D.6    Blom, A.M.7    Barlow, P.N.8
  • 59
    • 33746735499 scopus 로고    scopus 로고
    • Hydrophobic effect and hydrogen bonds account for the improved activity of a complement inhibitor, compstatin
    • Katragadda M., Magotti P., Sfyroera G., Lambris J.D. Hydrophobic effect and hydrogen bonds account for the improved activity of a complement inhibitor, compstatin. J. Med. Chem. 2006, 49:4616-4622.
    • (2006) J. Med. Chem. , vol.49 , pp. 4616-4622
    • Katragadda, M.1    Magotti, P.2    Sfyroera, G.3    Lambris, J.D.4
  • 61
    • 0034930015 scopus 로고    scopus 로고
    • C1-inhibitor: an anti-inflammatory reagent with therapeutic potential
    • Kirschfink M., Mollnes T.E. C1-inhibitor: an anti-inflammatory reagent with therapeutic potential. Expert Opin. Pharmacother. 2001, 2:1073-1083.
    • (2001) Expert Opin. Pharmacother. , vol.2 , pp. 1073-1083
    • Kirschfink, M.1    Mollnes, T.E.2
  • 63
    • 33845514506 scopus 로고    scopus 로고
    • Drug evaluation: the C5a receptor antagonist PMX-53
    • Köhl J. Drug evaluation: the C5a receptor antagonist PMX-53. Curr. Opin. Mol. Ther. 2006, 8:529-538.
    • (2006) Curr. Opin. Mol. Ther. , vol.8 , pp. 529-538
    • Köhl, J.1
  • 66
    • 51849090918 scopus 로고    scopus 로고
    • The artificial surface-induced whole blood inflammatory reaction revealed by increases in a series of chemokines and growth factors is largely complement dependent
    • Lappegard K.T., Bergseth G., Riesenfeld J., Pharo A., Magotti P., Lambris J.D., Mollnes T.E. The artificial surface-induced whole blood inflammatory reaction revealed by increases in a series of chemokines and growth factors is largely complement dependent. J. Biomed. Mater. Res. A 2008, 87:129-135.
    • (2008) J. Biomed. Mater. Res. A , vol.87 , pp. 129-135
    • Lappegard, K.T.1    Bergseth, G.2    Riesenfeld, J.3    Pharo, A.4    Magotti, P.5    Lambris, J.D.6    Mollnes, T.E.7
  • 67
    • 18844481981 scopus 로고    scopus 로고
    • Effect of complement inhibition and heparin coating on artificial surface-induced leukocyte and platelet activation
    • Lappegard K.T., Fung M., Bergseth G., Riesenfeld J., Lambris J.D., Videm V., Mollnes T.E. Effect of complement inhibition and heparin coating on artificial surface-induced leukocyte and platelet activation. Ann. Thorac. Surg. 2004, 77:932-941.
    • (2004) Ann. Thorac. Surg. , vol.77 , pp. 932-941
    • Lappegard, K.T.1    Fung, M.2    Bergseth, G.3    Riesenfeld, J.4    Lambris, J.D.5    Videm, V.6    Mollnes, T.E.7
  • 68
    • 33845700191 scopus 로고    scopus 로고
    • C1-esterase inhibitor reverses functional consequences of superior mesenteric artery ischemia/reperfusion by limiting reperfusion injury and restoring microcirculatory perfusion
    • Lauterbach M., Horstick G., Plum N., Lotz J., Lauterbach E., Weilemann L.S., Kempski O. C1-esterase inhibitor reverses functional consequences of superior mesenteric artery ischemia/reperfusion by limiting reperfusion injury and restoring microcirculatory perfusion. Shock 2007, 27:75-83.
    • (2007) Shock , vol.27 , pp. 75-83
    • Lauterbach, M.1    Horstick, G.2    Plum, N.3    Lotz, J.4    Lauterbach, E.5    Weilemann, L.S.6    Kempski, O.7
  • 69
    • 4644237694 scopus 로고    scopus 로고
    • Soluble human complement receptor 1 limits ischemic damage in cardiac surgery patients at high risk requiring cardiopulmonary bypass
    • OBE and the TP
    • Lazar H.L., Bokesch P.M., van L.F., Fitzgerald C., Emmett C., Marsh H.C., Ryan U., OBE and the TP Soluble human complement receptor 1 limits ischemic damage in cardiac surgery patients at high risk requiring cardiopulmonary bypass. Circulation 2004, 110:II274-II279.
    • (2004) Circulation , vol.110
    • Lazar, H.L.1    Bokesch, P.M.2    van, L.F.3    Fitzgerald, C.4    Emmett, C.5    Marsh, H.C.6    Ryan, U.7
  • 70
    • 34748814406 scopus 로고    scopus 로고
    • Beneficial effects of complement inhibition with soluble complement receptor 1 (TP10) during cardiac surgery: is there a gender difference?
    • Lazar H.L., Keilani T., Fitzgerald C.A., Shapira O.M., Hunter C.T., Shemin R.J., Marsh H.C., Ryan U.S. Beneficial effects of complement inhibition with soluble complement receptor 1 (TP10) during cardiac surgery: is there a gender difference?. Circulation 2007, 116:I83-I88.
    • (2007) Circulation , vol.116
    • Lazar, H.L.1    Keilani, T.2    Fitzgerald, C.A.3    Shapira, O.M.4    Hunter, C.T.5    Shemin, R.J.6    Marsh, H.C.7    Ryan, U.S.8
  • 71
    • 0031978419 scopus 로고    scopus 로고
    • Rapid activation of the complement system by cuprophane depends on complement component C4
    • Lhotta K., Wurzner R., Kronenberg F., Oppermann M., Konig P. Rapid activation of the complement system by cuprophane depends on complement component C4. Kidney Int. 1998, 53:1044-1051.
    • (1998) Kidney Int. , vol.53 , pp. 1044-1051
    • Lhotta, K.1    Wurzner, R.2    Kronenberg, F.3    Oppermann, M.4    Konig, P.5
  • 73
    • 33845505542 scopus 로고    scopus 로고
    • C1-inhibitor concentrate home therapy for hereditary angioedema: a viable, effective treatment option
    • Longhurst H.J., Carr S., Khair K. C1-inhibitor concentrate home therapy for hereditary angioedema: a viable, effective treatment option. Clin. Exp. Immunol. 2007, 147:11-17.
    • (2007) Clin. Exp. Immunol. , vol.147 , pp. 11-17
    • Longhurst, H.J.1    Carr, S.2    Khair, K.3
  • 74
    • 0023238665 scopus 로고
    • Plasma interleukin-1 activity in humans undergoing hemodialysis with regenerated cellulosic membranes
    • Lonnemann G., Bingel M., Koch K.M., Shaldon S., Dinarello C.A. Plasma interleukin-1 activity in humans undergoing hemodialysis with regenerated cellulosic membranes. Lymphokine Res. 1987, 6:63-70.
    • (1987) Lymphokine Res. , vol.6 , pp. 63-70
    • Lonnemann, G.1    Bingel, M.2    Koch, K.M.3    Shaldon, S.4    Dinarello, C.A.5
  • 76
    • 70349900541 scopus 로고    scopus 로고
    • Structure-kinetic relationship analysis of the therapeutic complement inhibitor compstatin
    • Magotti P., Ricklin D., Qu H., Wu Y.Q., Kaznessis Y.N., Lambris J.D. Structure-kinetic relationship analysis of the therapeutic complement inhibitor compstatin. J. Mol. Recognit. 2009, 22:495-505.
    • (2009) J. Mol. Recognit. , vol.22 , pp. 495-505
    • Magotti, P.1    Ricklin, D.2    Qu, H.3    Wu, Y.Q.4    Kaznessis, Y.N.5    Lambris, J.D.6
  • 77
    • 78349302747 scopus 로고    scopus 로고
    • Proteomic profiling of blood-dialyzer interactome reveals involvement of lectin complement pathway in hemodialysis-induced inflammatory response
    • Mares J., Richtrova P., Hricinova A., Tuma Z., Moravec J., Lysak D., Matejovic M. Proteomic profiling of blood-dialyzer interactome reveals involvement of lectin complement pathway in hemodialysis-induced inflammatory response. Proteomics Clin. Appl. 2010, 4:829-838.
    • (2010) Proteomics Clin. Appl. , vol.4 , pp. 829-838
    • Mares, J.1    Richtrova, P.2    Hricinova, A.3    Tuma, Z.4    Moravec, J.5    Lysak, D.6    Matejovic, M.7
  • 78
    • 68249092090 scopus 로고    scopus 로고
    • Specific adsorption of some complement activation proteins to polysulfone dialysis membranes during hemodialysis
    • Mares J., Thongboonkerd V., Tuma Z., Moravec J., Matejovic M. Specific adsorption of some complement activation proteins to polysulfone dialysis membranes during hemodialysis. Kidney Int. 2009, 76:404-413.
    • (2009) Kidney Int. , vol.76 , pp. 404-413
    • Mares, J.1    Thongboonkerd, V.2    Tuma, Z.3    Moravec, J.4    Matejovic, M.5
  • 82
    • 0342981748 scopus 로고    scopus 로고
    • Attenuation of changes in leukocyte surface markers and complement activation with heparin-coated cardiopulmonary bypass
    • Moen O., Hogasen K., Fosse E., Dregelid E., Brockmeier V., Venge P., Harboe M., Mollnes T.E. Attenuation of changes in leukocyte surface markers and complement activation with heparin-coated cardiopulmonary bypass. Ann. Thorac. Surg. 1997, 63:105-111.
    • (1997) Ann. Thorac. Surg. , vol.63 , pp. 105-111
    • Moen, O.1    Hogasen, K.2    Fosse, E.3    Dregelid, E.4    Brockmeier, V.5    Venge, P.6    Harboe, M.7    Mollnes, T.E.8
  • 83
    • 0028784590 scopus 로고
    • A new model for evaluation of biocompatibility: combined determination of neoepitopes in blood and on artificial surfaces demonstrates reduced complement activation by immobilization of heparin
    • Mollnes T.E., Riesenfeld J., Garred P., Nordstrom E., Hogasen K., Fosse E., Gotze O., Harboe M. A new model for evaluation of biocompatibility: combined determination of neoepitopes in blood and on artificial surfaces demonstrates reduced complement activation by immobilization of heparin. Artif. Organs 1995, 19:909-917.
    • (1995) Artif. Organs , vol.19 , pp. 909-917
    • Mollnes, T.E.1    Riesenfeld, J.2    Garred, P.3    Nordstrom, E.4    Hogasen, K.5    Fosse, E.6    Gotze, O.7    Harboe, M.8
  • 84
    • 34848884555 scopus 로고    scopus 로고
    • Effect of supraphysiologic levels of C1-inhibitor on the classical, lectin and alternative pathways of complement
    • Nielsen E.W., Waage C., Fure H., Brekke O.L., Sfyroera G., Lambris J.D., Mollnes T.E. Effect of supraphysiologic levels of C1-inhibitor on the classical, lectin and alternative pathways of complement. Mol. Immunol. 2007, 44:1819-1826.
    • (2007) Mol. Immunol. , vol.44 , pp. 1819-1826
    • Nielsen, E.W.1    Waage, C.2    Fure, H.3    Brekke, O.L.4    Sfyroera, G.5    Lambris, J.D.6    Mollnes, T.E.7
  • 85
    • 0026092235 scopus 로고
    • The principal site of glycation of human complement factor B
    • Niemann M.A., Bhown A.S., Miller E.J. The principal site of glycation of human complement factor B. Biochem. J. 1991, 274(Pt 2):473-480.
    • (1991) Biochem. J. , vol.274 , Issue.PART 2 , pp. 473-480
    • Niemann, M.A.1    Bhown, A.S.2    Miller, E.J.3
  • 87
    • 73149108627 scopus 로고    scopus 로고
    • Can cells and biomaterials in therapeutic medicine be shielded from innate immune recognition?
    • Nilsson B., Korsgren O., Lambris J.D., Ekdahl K.N. Can cells and biomaterials in therapeutic medicine be shielded from innate immune recognition?. Trends Immunol. 2010, 31:32-38.
    • (2010) Trends Immunol. , vol.31 , pp. 32-38
    • Nilsson, B.1    Korsgren, O.2    Lambris, J.D.3    Ekdahl, K.N.4
  • 88
    • 0032170593 scopus 로고    scopus 로고
    • Compstatin inhibits complement and cellular activation in whole blood in two models of extracorporeal circulation
    • Nilsson B., Larsson R., Hong J., Elgue G., Ekdahl K.N., Sahu A., Lambris J.D. Compstatin inhibits complement and cellular activation in whole blood in two models of extracorporeal circulation. Blood 1998, 92:1661-1667.
    • (1998) Blood , vol.92 , pp. 1661-1667
    • Nilsson, B.1    Larsson, R.2    Hong, J.3    Elgue, G.4    Ekdahl, K.N.5    Sahu, A.6    Lambris, J.D.7
  • 89
    • 0034874856 scopus 로고    scopus 로고
    • Deposition of C3b/iC3b leads to the concealment of antigens, immunoglobulins and bound C1q in complement-activating immune complexes
    • Nilsson U.R. Deposition of C3b/iC3b leads to the concealment of antigens, immunoglobulins and bound C1q in complement-activating immune complexes. Mol. Immunol. 2001, 38:151-160.
    • (2001) Mol. Immunol. , vol.38 , pp. 151-160
    • Nilsson, U.R.1
  • 90
    • 84892622409 scopus 로고    scopus 로고
    • NKUDIC. Kidney and Urologic Diseases Statistics for the United States. Source: National Kidney & Urologic Diseases Information Clearinghouse (NKUDIC) - A service of the National Institute of Diabetes and Digestive Kidney Diseases (NIDDK) - National Institutes of Health (NIH).
    • NKUDIC, 2012. Kidney and Urologic Diseases Statistics for the United States. Source: National Kidney & Urologic Diseases Information Clearinghouse (NKUDIC) - A service of the National Institute of Diabetes and Digestive Kidney Diseases (NIDDK) - National Institutes of Health (NIH). http://kidney.niddk.nih.gov/kudiseases/pubs/kustats/.
    • (2012)
  • 91
    • 84857532767 scopus 로고    scopus 로고
    • Interactions between coagulation and complement - their role in inflammation
    • Oikonomopoulou K., Ricklin D., Ward P.A., Lambris J.D. Interactions between coagulation and complement - their role in inflammation. Semin. Immunopathol. 2012, 34:151-165.
    • (2012) Semin. Immunopathol. , vol.34 , pp. 151-165
    • Oikonomopoulou, K.1    Ricklin, D.2    Ward, P.A.3    Lambris, J.D.4
  • 92
    • 0000053419 scopus 로고
    • Partial purification of a serum inhibitor of C'1-esterase
    • Pensky J., Levy L.R., Lepow I.H. Partial purification of a serum inhibitor of C'1-esterase. J. Biol. Chem. 1961, 236:1674-1679.
    • (1961) J. Biol. Chem. , vol.236 , pp. 1674-1679
    • Pensky, J.1    Levy, L.R.2    Lepow, I.H.3
  • 93
    • 84866028050 scopus 로고    scopus 로고
    • Effect of the dialysis membrane on mortality of chronic hemodialysis patients. Hakim RM, Held PJ, Stannard DC, Wolfe RA, Port FK, Daugirdas JT, Agadoa L
    • Semin. Dial. 10, 61-62
    • Pereira B.J. Effect of the dialysis membrane on mortality of chronic hemodialysis patients. Hakim RM, Held PJ, Stannard DC, Wolfe RA, Port FK, Daugirdas JT, Agadoa L. Kidney Int. 1997, 1996(50):566-570. Semin. Dial. 10, 61-62.
    • (1997) Kidney Int. , vol.1996 , Issue.50 , pp. 566-570
    • Pereira, B.J.1
  • 94
    • 0028175027 scopus 로고
    • Plasma levels of IL-1 beta, TNF alpha and their specific inhibitors in undialyzed chronic renal failure, CAPD and hemodialysis patients
    • Pereira B.J., Shapiro L., King A.J., Falagas M.E., Strom J.A., Dinarello C.A. Plasma levels of IL-1 beta, TNF alpha and their specific inhibitors in undialyzed chronic renal failure, CAPD and hemodialysis patients. Kidney Int. 1994, 45:890-896.
    • (1994) Kidney Int. , vol.45 , pp. 890-896
    • Pereira, B.J.1    Shapiro, L.2    King, A.J.3    Falagas, M.E.4    Strom, J.A.5    Dinarello, C.A.6
  • 95
    • 33646923133 scopus 로고    scopus 로고
    • Extreme sequence divergence but conserved ligand-binding specificity in Streptococcus pyogenes M protein
    • Persson J., Beall B., Linse S., Lindahl G. Extreme sequence divergence but conserved ligand-binding specificity in Streptococcus pyogenes M protein. PLoS Pathog. 2006, 2:e47.
    • (2006) PLoS Pathog. , vol.2
    • Persson, J.1    Beall, B.2    Linse, S.3    Lindahl, G.4
  • 96
    • 2442652561 scopus 로고    scopus 로고
    • Influence of initiation of maintenance hemodialysis on biomarkers of inflammation and oxidative stress
    • Pupim L.B., Himmelfarb J., McMonagle E., Shyr Y., Ikizler T.A. Influence of initiation of maintenance hemodialysis on biomarkers of inflammation and oxidative stress. Kidney Int. 2004, 65:2371-2379.
    • (2004) Kidney Int. , vol.65 , pp. 2371-2379
    • Pupim, L.B.1    Himmelfarb, J.2    McMonagle, E.3    Shyr, Y.4    Ikizler, T.A.5
  • 97
    • 78650620316 scopus 로고    scopus 로고
    • Novel analogues of the therapeutic complement inhibitor compstatin with significantly improved affinity and potency
    • Qu H., Magotti P., Ricklin D., Wu E.L., Kourtzelis I., Wu Y.Q., Kaznessis Y.N., Lambris J.D. Novel analogues of the therapeutic complement inhibitor compstatin with significantly improved affinity and potency. Mol. Immunol. 2011, 48:481-489.
    • (2011) Mol. Immunol. , vol.48 , pp. 481-489
    • Qu, H.1    Magotti, P.2    Ricklin, D.3    Wu, E.L.4    Kourtzelis, I.5    Wu, Y.Q.6    Kaznessis, Y.N.7    Lambris, J.D.8
  • 99
    • 70450224874 scopus 로고    scopus 로고
    • Recent developments in low molecular weight complement inhibitors
    • Qu H., Ricklin D., Lambris J.D. Recent developments in low molecular weight complement inhibitors. Mol. Immunol. 2009, 47:185-195.
    • (2009) Mol. Immunol. , vol.47 , pp. 185-195
    • Qu, H.1    Ricklin, D.2    Lambris, J.D.3
  • 101
    • 77955883153 scopus 로고    scopus 로고
    • Complement: a key system for immune surveillance and homeostasis
    • Ricklin D., Hajishengallis G., Yang K., Lambris J.D. Complement: a key system for immune surveillance and homeostasis. Nat. Immunol. 2010, 11:785-797.
    • (2010) Nat. Immunol. , vol.11 , pp. 785-797
    • Ricklin, D.1    Hajishengallis, G.2    Yang, K.3    Lambris, J.D.4
  • 102
    • 52649116114 scopus 로고    scopus 로고
    • Compstatin: a complement inhibitor on its way to clinical application
    • Ricklin D., Lambris J.D. Compstatin: a complement inhibitor on its way to clinical application. Adv. Exp. Med. Biol. 2008, 632:273-292.
    • (2008) Adv. Exp. Med. Biol. , vol.632 , pp. 273-292
    • Ricklin, D.1    Lambris, J.D.2
  • 103
    • 84934440020 scopus 로고    scopus 로고
    • Progress and trends in complement therapeutics
    • in press.
    • Ricklin, D., Lambris, J.D., 2012. Progress and trends in complement therapeutics. Adv. Exp. Med. Biol., in press.
    • (2012) Adv. Exp. Med. Biol.
    • Ricklin, D.1    Lambris, J.D.2
  • 104
    • 36048937343 scopus 로고    scopus 로고
    • Complement-targeted therapeutics
    • Ricklin D., Lambris J.D. Complement-targeted therapeutics. Nat. Biotechnol. 2007, 25:1265-1275.
    • (2007) Nat. Biotechnol. , vol.25 , pp. 1265-1275
    • Ricklin, D.1    Lambris, J.D.2
  • 105
    • 79959467643 scopus 로고    scopus 로고
    • Achievements and limitations of complement inhibition by eculizumab in paroxysmal nocturnal hemoglobinuria: the role of complement component 3
    • Risitano A.M., Perna F., Selleri C. Achievements and limitations of complement inhibition by eculizumab in paroxysmal nocturnal hemoglobinuria: the role of complement component 3. Mini Rev. Med. Chem. 2011, 11:528-535.
    • (2011) Mini Rev. Med. Chem. , vol.11 , pp. 528-535
    • Risitano, A.M.1    Perna, F.2    Selleri, C.3
  • 106
    • 0037210289 scopus 로고    scopus 로고
    • Compstatin, a peptide inhibitor of complement, exhibits species-specific binding to complement component C3
    • Sahu A., Morikis D., Lambris J.D. Compstatin, a peptide inhibitor of complement, exhibits species-specific binding to complement component C3. Mol. Immunol. 2003, 39:557-566.
    • (2003) Mol. Immunol. , vol.39 , pp. 557-566
    • Sahu, A.1    Morikis, D.2    Lambris, J.D.3
  • 107
    • 0034041483 scopus 로고    scopus 로고
    • Effect of the hemodialysis membrane on the inflammatory reaction in vivo
    • Schindler R., Boenisch O., Fischer C., Frei U. Effect of the hemodialysis membrane on the inflammatory reaction in vivo. Clin. Nephrol. 2000, 53:452-459.
    • (2000) Clin. Nephrol. , vol.53 , pp. 452-459
    • Schindler, R.1    Boenisch, O.2    Fischer, C.3    Frei, U.4
  • 108
    • 0344306456 scopus 로고    scopus 로고
    • Inhibitor of complement, Compstatin, prevents polymer-mediated Mac-1 up-regulation of human neutrophils independent of biomaterial type tested
    • Schmidt S., Haase G., Csomor E., Lutticken R., Peltroche-Llacsahuanga H. Inhibitor of complement, Compstatin, prevents polymer-mediated Mac-1 up-regulation of human neutrophils independent of biomaterial type tested. J. Biomed. Mater. Res. A 2003, 66:491-499.
    • (2003) J. Biomed. Mater. Res. A , vol.66 , pp. 491-499
    • Schmidt, S.1    Haase, G.2    Csomor, E.3    Lutticken, R.4    Peltroche-Llacsahuanga, H.5
  • 112
    • 77953307215 scopus 로고    scopus 로고
    • Modifying apolipoprotein A-I by malondialdehyde, but not by an array of other reactive carbonyls, blocks cholesterol efflux by the ABCA1 pathway
    • Shao B., Pennathur S., Pagani I., Oda M.N., Witztum J.L., Oram J.F., Heinecke J.W. Modifying apolipoprotein A-I by malondialdehyde, but not by an array of other reactive carbonyls, blocks cholesterol efflux by the ABCA1 pathway. J. Biol. Chem. 2010, 285:18473-18484.
    • (2010) J. Biol. Chem. , vol.285 , pp. 18473-18484
    • Shao, B.1    Pennathur, S.2    Pagani, I.3    Oda, M.N.4    Witztum, J.L.5    Oram, J.F.6    Heinecke, J.W.7
  • 114
    • 67649397446 scopus 로고    scopus 로고
    • Inflammation in chronic kidney disease: role in the progression of renal and cardiovascular disease
    • Silverstein D.M. Inflammation in chronic kidney disease: role in the progression of renal and cardiovascular disease. Pediatr. Nephrol. 2009, 24:1445-1452.
    • (2009) Pediatr. Nephrol. , vol.24 , pp. 1445-1452
    • Silverstein, D.M.1
  • 116
    • 0036719916 scopus 로고    scopus 로고
    • Inflammation in end-stage renal disease: sources, consequences, and therapy
    • Stenvinkel P., Alvestrand A. Inflammation in end-stage renal disease: sources, consequences, and therapy. Semin. Dial. 2002, 15:329-337.
    • (2002) Semin. Dial. , vol.15 , pp. 329-337
    • Stenvinkel, P.1    Alvestrand, A.2
  • 119
    • 0028831310 scopus 로고
    • Ig-binding surface proteins of Streptococcus pyogenes also bind human C4b-binding protein (C4BP), a regulatory component of the complement system
    • Thern A., Stenberg L., Dahlback B., Lindahl G. Ig-binding surface proteins of Streptococcus pyogenes also bind human C4b-binding protein (C4BP), a regulatory component of the complement system. J. Immunol. 1995, 154:375-386.
    • (1995) J. Immunol. , vol.154 , pp. 375-386
    • Thern, A.1    Stenberg, L.2    Dahlback, B.3    Lindahl, G.4
  • 120
    • 79953089697 scopus 로고    scopus 로고
    • Biocompatibility and pathways of initial complement pathway activation with Phisio- and PMEA-coated cardiopulmonary bypass circuits during open-heart surgery
    • Thiara A.S., Mollnes T.E., Videm V., Andersen V.Y., Svennevig K., Kolset S.O., Fiane A.E. Biocompatibility and pathways of initial complement pathway activation with Phisio- and PMEA-coated cardiopulmonary bypass circuits during open-heart surgery. Perfusion 2011, 26:107-114.
    • (2011) Perfusion , vol.26 , pp. 107-114
    • Thiara, A.S.1    Mollnes, T.E.2    Videm, V.3    Andersen, V.Y.4    Svennevig, K.5    Kolset, S.O.6    Fiane, A.E.7
  • 121
    • 52249110240 scopus 로고    scopus 로고
    • Quantitative screening of protein glycation, oxidation, and nitration adducts by LC-MS/MS: protein damage in diabetes, uremia, cirrhosis, and Alzheimer's disease
    • John Wiley & Sons, Inc. I. Dalle-Donne, A. Scaloni, D.A. Butterfield (Eds.)
    • Thornalley P.J. Quantitative screening of protein glycation, oxidation, and nitration adducts by LC-MS/MS: protein damage in diabetes, uremia, cirrhosis, and Alzheimer's disease. Redox Proteomics: From Protein Modifications to Cellular Dysfunction and Diseases 2006, 681-727. John Wiley & Sons, Inc. I. Dalle-Donne, A. Scaloni, D.A. Butterfield (Eds.).
    • (2006) Redox Proteomics: From Protein Modifications to Cellular Dysfunction and Diseases , pp. 681-727
    • Thornalley, P.J.1
  • 122
    • 0242468729 scopus 로고    scopus 로고
    • Quantitative screening of advanced glycation endproducts in cellular and extracellular proteins by tandem mass spectrometry
    • Thornalley P.J., Battah S., Ahmed N., Karachalias N., Agalou S., Babaei-Jadidi R., Dawnay A. Quantitative screening of advanced glycation endproducts in cellular and extracellular proteins by tandem mass spectrometry. Biochem. J. 2003, 375:581-592.
    • (2003) Biochem. J. , vol.375 , pp. 581-592
    • Thornalley, P.J.1    Battah, S.2    Ahmed, N.3    Karachalias, N.4    Agalou, S.5    Babaei-Jadidi, R.6    Dawnay, A.7
  • 123
    • 0033571012 scopus 로고    scopus 로고
    • Formation of glyoxal, methylglyoxal and 3-deoxyglucosone in the glycation of proteins by glucose
    • Thornalley P.J., Langborg A., Minhas H.S. Formation of glyoxal, methylglyoxal and 3-deoxyglucosone in the glycation of proteins by glucose. Biochem. J. 1999, 344(Pt1):109-116.
    • (1999) Biochem. J. , vol.344 , Issue.PART 1 , pp. 109-116
    • Thornalley, P.J.1    Langborg, A.2    Minhas, H.S.3
  • 124
    • 78650117871 scopus 로고    scopus 로고
    • Protein damage in diabetes and uremia - identifying hotspots of proteome damage where minimal modification is amplified to marked pathophysiological effect
    • Thornalley P.J., Rabbani N. Protein damage in diabetes and uremia - identifying hotspots of proteome damage where minimal modification is amplified to marked pathophysiological effect. Free Radic. Res. 2011, 45:89-100.
    • (2011) Free Radic. Res. , vol.45 , pp. 89-100
    • Thornalley, P.J.1    Rabbani, N.2
  • 125
    • 84903853006 scopus 로고    scopus 로고
    • Biocompatible characteristics of high-performance membranes
    • Uda S., Mizobuchi M., Akizawa T. Biocompatible characteristics of high-performance membranes. Contrib. Nephrol. 2011, 173:23-29.
    • (2011) Contrib. Nephrol. , vol.173 , pp. 23-29
    • Uda, S.1    Mizobuchi, M.2    Akizawa, T.3
  • 128
    • 22344458137 scopus 로고    scopus 로고
    • Atorvastatin in patients with type 2 diabetes mellitus undergoing hemodialysis
    • German Diabetes and Dialysis Study Investigators
    • Wanner C., Krane V., Marz W., Olschewski M., Mann J.F., Ruf G., Ritz E., German Diabetes and Dialysis Study Investigators Atorvastatin in patients with type 2 diabetes mellitus undergoing hemodialysis. N. Engl. J. Med. 2005, 353:238-248.
    • (2005) N. Engl. J. Med. , vol.353 , pp. 238-248
    • Wanner, C.1    Krane, V.2    Marz, W.3    Olschewski, M.4    Mann, J.F.5    Ruf, G.6    Ritz, E.7
  • 130
    • 79954997898 scopus 로고    scopus 로고
    • Protection of nonself surfaces from complement attack by factor H-binding peptides: implications for therapeutic medicine
    • Wu Y.Q., Qu H., Sfyroera G., Tzekou A., Kay B.K., Nilsson B., Nilsson E.K., Ricklin D., Lambris J.D. Protection of nonself surfaces from complement attack by factor H-binding peptides: implications for therapeutic medicine. J. Immunol. 2011, 186:4269-4277.
    • (2011) J. Immunol. , vol.186 , pp. 4269-4277
    • Wu, Y.Q.1    Qu, H.2    Sfyroera, G.3    Tzekou, A.4    Kay, B.K.5    Nilsson, B.6    Nilsson, E.K.7    Ricklin, D.8    Lambris, J.D.9
  • 131
    • 10044239335 scopus 로고    scopus 로고
    • Chronic systemic inflammation in dialysis patients: an update on causes and consequences
    • Yao Q., Axelsson J., Stenvinkel P., Lindholm B. Chronic systemic inflammation in dialysis patients: an update on causes and consequences. ASAIO J. 2004, 50:lii-lvii.
    • (2004) ASAIO J. , vol.50
    • Yao, Q.1    Axelsson, J.2    Stenvinkel, P.3    Lindholm, B.4
  • 132
    • 0034004568 scopus 로고    scopus 로고
    • C-Reactive protein predicts all-cause and cardiovascular mortality in hemodialysis patients
    • Yeun J.Y., Levine R.A., Mantadilok V., Kaysen G.A. C-Reactive protein predicts all-cause and cardiovascular mortality in hemodialysis patients. Am. J. Kidney Dis. 2000, 35:469-476.
    • (2000) Am. J. Kidney Dis. , vol.35 , pp. 469-476
    • Yeun, J.Y.1    Levine, R.A.2    Mantadilok, V.3    Kaysen, G.A.4
  • 133
  • 134
    • 0032935896 scopus 로고    scopus 로고
    • Inflammation enhances cardiovascular risk and mortality in hemodialysis patients
    • Zimmermann J., Herrlinger S., Pruy A., Metzger T., Wanner C. Inflammation enhances cardiovascular risk and mortality in hemodialysis patients. Kidney Int. 1999, 55:648-658.
    • (1999) Kidney Int. , vol.55 , pp. 648-658
    • Zimmermann, J.1    Herrlinger, S.2    Pruy, A.3    Metzger, T.4    Wanner, C.5
  • 135
    • 70349437186 scopus 로고    scopus 로고
    • Complement regulators and inhibitory proteins
    • Zipfel P.F., Skerka C. Complement regulators and inhibitory proteins. Nat. Rev. Immunol. 2009, 9:729-740.
    • (2009) Nat. Rev. Immunol. , vol.9 , pp. 729-740
    • Zipfel, P.F.1    Skerka, C.2


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