Hyperglycemic conditions inhibit C3-mediated immunologic control of Staphylococcus aureus

Journal of Translational Medicine

Volumn 10, Issue 1, 2012, Pages

  Hair, Pamela S ^a   Echague, Charlene G ^a   Rohn, Reuben D ^a,b,c   Krishna, Neel K ^a,b   Nyalwidhe, Julius O ^a   Cunnion, Kenji M ^a,b,c  

^a EASTERN VIRGINIA MEDICAL SCHOOL   (United States)

^b Children's Specialty Group   (United States)

^c CHILDREN S HOSPITAL OF THE KING S DAUGHTERS   (United States)

Author keywords

Complement C3; Hyperglycemia; Immune evasion; Polymicrobial infection; Staphylococcus aureus

Indexed keywords

COMPLEMENT COMPONENT C3; GLUCOSE; CLASSICAL COMPLEMENT PATHWAY C3 C5 CONVERTASE; OPSONIN;

ARTICLE; BACTERICIDAL ACTIVITY; COMPLEMENT ACTIVATION; COMPLEMENT DEPOSITION; CONTROLLED STUDY; GLYCATION; HUMAN; HUMAN CELL; HYPERGLYCEMIA; MASS SPECTROMETRY; NONHUMAN; OPSONIZATION; PHAGOCYTOSIS; PROTEIN TERTIARY STRUCTURE; STAPHYLOCOCCUS AUREUS; AMINO ACID SEQUENCE; CHEMICAL STRUCTURE; CHEMISTRY; CYTOTOXICITY; DRUG EFFECT; ESCHERICHIA COLI; GLYCOSYLATION; IMMUNOLOGY; ISOLATION AND PURIFICATION; METABOLISM; MICROBIAL VIABILITY; MICROBIOLOGY; MOLECULAR GENETICS; PROTEIN BINDING; STAPHYLOCOCCUS INFECTION;

AMINO ACID SEQUENCE; COMPLEMENT C3; COMPLEMENT C3-C5 CONVERTASES; CYTOTOXICITY, IMMUNOLOGIC; ESCHERICHIA COLI; GLUCOSE; GLYCOSYLATION; HUMANS; HYPERGLYCEMIA; MASS SPECTROMETRY; MICROBIAL VIABILITY; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; OPSONIN PROTEINS; PHAGOCYTOSIS; PROTEIN BINDING; STAPHYLOCOCCAL INFECTIONS; STAPHYLOCOCCUS AUREUS;

EID: 84857681018     PISSN: None     EISSN: 14795876     Source Type: Journal    
DOI: 10.1186/1479-5876-10-35     Document Type: Article

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