Deposition of C3b/iC3b leads to the concealment of antigens, immunoglobulins and bound C1q in complement-activating immune complexes

Molecular Immunology

Volumn 38, Issue 2-3, 2001, Pages 151-160

  Nilsson, U R ^a  

^a UPPSALA UNIVERSITY   (Sweden)

Author keywords

C1; C3; Complement; Concealment; IgG; Immune complex

Indexed keywords

ANTIGEN; BOVINE SERUM ALBUMIN; COMPLEMENT COMPONENT C1Q; COMPLEMENT COMPONENT C3B; IMMUNOGLOBULIN G; IMMUNOGLOBULIN G ANTIBODY; LIGAND; MEMBRANE ANTIGEN; MEMBRANE RECEPTOR; REAGENT;

ADSORPTION; ANTIGEN ANTIBODY COMPLEX; ANTIGEN BINDING; COMPLEMENT ACTIVATION; COMPLEMENT DEPOSITION; CONFERENCE PAPER; CONTROLLED STUDY; DOWN REGULATION; HUMAN; IMMUNE RESPONSE; LEUKOCYTE; NORMAL HUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN INTERACTION; PROTEIN SECRETION; QUANTITATIVE ASSAY; SERUM; TEMPERATURE; TITRIMETRY;

ANTIGEN-ANTIBODY COMPLEX; ANTIGENS; COMPLEMENT ACTIVATION; COMPLEMENT C1Q; COMPLEMENT C3B; HUMANS; IMMUNOGLOBULIN G; PROTEIN BINDING; SERUM ALBUMIN, BOVINE;

EID: 0034874856     PISSN: 01615890     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0161-5890(01)00039-6     Document Type: Conference Paper

References (21)

1. Fixation of C3 to IgG attenuates neutrophil HOCl generation and collagenase activation
2. Large scale isolation of functionally active components of the human complement system
3. Differences in the ingestion mechanisms of IgG and C3b particles in phagocytosis by neutrophils
4. Characterization of human antibody to polyribophosphate, the capsular antigen of Hemophilus influenzae, type B
5. The role of complement in the stimulation of lysosomal enzyme release by polymorphonuclear leucocytes induced by immune complexes of IgG and of IgM
6. Molecular composition of complement-solubilized complexes and their fate in vivo
7. The first component of complement. I. Purification and properties of native C1
8. Methods for the separation, purification and measurement of nine components of hemolytic complement in guinea-pig serum
9. Role of binding through C3b and IgG in polymorphonuclear neutrophil function: Studies with trypsin-generated C3b
10. Simplified assays of hemolytic activity of the classical and alternative complement pathways
11. CR3 (CD11b, CD18): A phagocyte and NK cell membrane receptor with multiple ligand specificities and functions
12. Ligation of CR1 attenuates Fc receptor-mediated myeloperoxidase release and HOCl production by neutrophils
13. Solubilization of antigen-antibody complexes: A new function of complement as a regulator of immune reactions
14. Complement activation by IgG immobilized on methylated silicon
15. Inherited human complement C5 deficiency. Nonsense mutations in exons 1 (Gln1 to Stop) and 36 (Arg1458 to Stop) and compound heterozygosity in three African-American families
16. Quantitative phagocytosis by neutrophils. I. A new method with immune complexes
17. Rapid isolation and biochemical characterization of rat C1 and C1q
18. The role of complement in the host's defense against Haemophilus influenzae
19. Chemical studies of Clq; a modulator of immunoglobulin biology
20. CR3 (Mac-1, alpha M beta 2, CD11b/CD18) and Fc gamma RIII cooperate in generation of a neutrophil respiratory burst: Requirement for Fc gamma RIII and tyrosine phosphorylation