Proteomic profiling of blood-dialyzer interactome reveals involvement of lectin complement pathway in hemodialysis-induced inflammatory response

Proteomics - Clinical Applications

Volumn 4, Issue 10-11, 2010, Pages 829-838

  Mares, Jan ^a   Richtrova, Pavlina ^a   Hricinova, Alena ^a   Tuma, Zdenek ^a   Moravec, Jiri ^a   Lysak, Daniel ^a   Matejovic, Martin ^a  

^a CHARLES UNIVERSITY   (Czech Republic)

Author keywords

Complement; Hemodialysis; Lectin; Leukopenia; Polysulfone

Indexed keywords

ACTIN; CALDESMON; COMPLEMENT COMPONENT C3C; COMPLEMENT COMPONENT C5A; FICOLIN 2; L SELECTIN; LECTIN; MANNAN BINDING LECTIN ASSOCIATED SERINE PROTEINASE; POLYSULFONE; PROPERDIN; TROPOMYOSIN; UNCLASSIFIED DRUG; VINCULIN; VITRONECTIN;

ADSORPTION; AGED; AMINO ACID SEQUENCE; ANTIGEN EXPRESSION; ARTICLE; BIOCOMPATIBILITY; BLOOD SAMPLING; CELL ADHESION; COMPLEMENT ACTIVATION; COMPLEMENT BLOOD LEVEL; COMPLEMENT LECTIN PATHWAY; ELUTION; HEMODIALYSIS; HUMAN; HUMAN TISSUE; INFLAMMATION; INNATE IMMUNITY; LEUKOCYTE COUNT; LEUKOPENIA; MAJOR CLINICAL STUDY; MASS SPECTROMETRY; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BLOOD LEVEL; PROTEIN DEPLETION; PROTEOMICS; THROMBOCYTE COUNT;

ADSORPTION; COMPLEMENT PATHWAY, MANNOSE-BINDING LECTIN; GENE EXPRESSION PROFILING; HUMANS; INFLAMMATION; LECTINS; MEMBRANES, ARTIFICIAL; POLYMERS; PROTEOME; RENAL DIALYSIS; SULFONES;

EID: 78349302747     PISSN: 18628346     EISSN: 18628354     Source Type: Journal    
DOI: 10.1002/prca.201000031     Document Type: Article

References (37)

1. Grassmann, A., Gioberge, S., Moeller, S., Brown, G., End-stage renal disease: global demographics in 2005 and observed trends. Artif. Organs 2006, 30, 895-897.
2. Goodkin, D. A., Bragg-Gresham, J. L., Koenig, K. G., Wolfe, R. A. et al., Association of comorbid conditions and mortality in hemodialysis patients in Europe, Japan, and the United States: the Dialysis Outcomes and Practice Patterns Study (DOPPS). J. Am. Soc. Nephrol. 2003, 14, 3270-3277.
3. Jofre, R., Rodriguez-Benitez, P., Lopez-Gomez, J. M., Perez-Garcia, R., Inflammatory syndrome in patients on hemodialysis. J. Am. Soc. Nephrol. 2006, 17, S274-S280.
4. MacLeod, A., Daly, C., Khan, I., Vale, L. et al., Comparison of cellulose, modified cellulose and synthetic membranes in the haemodialysis of patients with end-stage renal disease. Cochrane Database Syst. Rev. 2005, DOI: 10.1002/14651858. CD003234. pub2.
5. Hernandez, M. R., Galan, A. M., Cases, A., Lopez-Pedret, J. et al., Biocompatibility of cellulosic and synthetic membranes assessed by leukocyte activation. Am. J. Nephrol. 2004, 24, 235-241.
6. Nilsson, B., Ekdahl, K. N., Mollnes, T. E., Lambris, J. D., The role of complement in biomaterial-induced inflammation. Mol. Immunol. 2007, 44, 82-94.
7. Lhotta, K., Wurzner, R., Kronenberg, F., Oppermann, M., Konig, P., Rapid activation of the complement system by cuprophane depends on complement component C4. Kidney Int. 1998, 53, 1044-1051.
8. Craddock, P. R., Fehr, J., Dalmasso, A. P., Brighan, K. L., Jacob, H. S., Hemodialysis leukopenia. Pulmonary vascular leukostasis resulting from complement activation by dialyzer cellophane membranes. J. Clin. Invest. 1977, 59, 879-888.
9. Mares, J., Thongboonkerd, V., Tuma, Z., Moravec, J. et al., Proteomic analysis of proteins bound to adsorption units of extracorporeal liver support system under clinical conditions. J. Proteome Res. 2009, 8, 1756-1764.
10. Mares, J., Thongboonkerd, V., Tuma, Z., Moravec, J., Matejovic, M., Specific adsorption of some complement activation proteins to polysulfone dialysis membranes during hemodialysis. Kidney Int. 2009, 76, 404-413.
11. Sachon, E., Matheron, L., Clodic, G., Blasco, T., Bolbach, G., MALDI TOF-TOF characterization of a light stabilizer polymer contaminant from polypropylene or polyethylene plastic test tubes. J. Mass Spectrom. 2010, 45, 43-50.
12. Matsushita, M., Fujita, T., Ficolins and the lectin complement pathway. Immunol. Rev. 2001, 180, 78-85.
13. Harboe, M., Mollnes, T. E., The alternative complement pathway revisited. J. Cell. Mol. Med. 2008, 12, 1074-1084.
14. Kemper, C., Hourcade, D. E., Properdin: new roles in pattern recognition and target clearance. Mol. Immunol. 2008, 45, 4048-4056.
15. Xu, P., Crawford, M., Way, M., Godovac-Zimmermann, J. et al., Subproteome analysis of the neutrophil cytoskeleton. Proteomics 2009, 9, 2037-2049.
16. Asijee, G. M., Sturk, A., Bruin, T., Wilkinson, J. M., Ten Cate, J. W., Vinculin is a permanent component of the membrane skeleton and is incorporated into the (re)organising cytoskeleton upon platelet activation. Eur. J. Biochem. 1990, 189, 131-136.
17. Wernimont, S. A., Cortesio, C. L., Simonson, W. T., Huttenlocher, A., Adhesions ring: a structural comparison between podosomes and the immune synapse. Eur. J. Cell. Biol. 2008, 87, 507-515.
18. Jenney, C. R., Anderson, J. M., Adsorbed serum proteins responsible for surface dependent human macrophage behavior. J. Biomed. Mater. Res. 2000, 49, 435-447.
19. Jog, N. R., Rane, M. J., Lominadze, G., Luerman, G. C. et al., The actin cytoskeleton regulates exocytosis of all neutrophil granule subsets. Am. J. Physiol. Cell. Physiol. 2007, 292, C1690-C1700.
20. Lausen, M., Lynch, N., Schlosser, A., Tornoe, I. et al., Microfibril-associated protein 4 is present in lung washings and binds to the collagen region of lung surfactant protein D. J. Biol. Chem. 1999, 274, 32234-32240.
21. Presanis, J. S., Hajela, K., Ambrus, G., Gal, P., Sim, R. B., Differential substrate and inhibitor profiles for human MASP-1 and MASP-2. Mol. Immunol. 2004, 40, 921-929.
22. Hummelshoj, T., Thielens, N. M., Madsen, H. O., Arlaud, G. J. et al., Molecular organization of human Ficolin-2. Mol. Immunol. 2007, 44, 401-411.
23. Cseh, S., Vera, L., Matsushita, M., Fujita, T. et al., Characterization of the interaction between L-ficolin/p35 and mannan-binding lectin-associated serine proteases-1 and -2. J. Immunol. 2002, 169, 5735-5743.
24. Runza, V. L., Schwaeble, W., Mannel, D. N., Ficolins: novel pattern recognition molecules of the innate immune response. Immunobiology 2008, 213, 297-306.
25. Aoyagi, Y., Adderson, E. E., Rubens, C. E., Bohnsack, J. F. et al., L-Ficolin/mannose-binding lectin-associated serine protease complexes bind to group B streptococci primarily through N-acetylneuraminic acid of capsular polysaccharide and activate the complement pathway. Infect. Immun. 2008, 76, 179-188.
26. Lynch, N. J., Roscher, S., Hartung, T., Morath, S. et al., L-ficolin specifically binds to lipoteichoic acid, a cell wall constituent of Gram-positive bacteria, and activates the lectin pathway of complement. J. Immunol. 2004, 172, 1198-1202.
27. Matsushita, M., Endo, Y., Taira, S., Sato, Y. et al., A novel human serum lectin with collagen- and fibrinogen-like domains that functions as an opsonin. J. Biol. Chem. 1996, 271, 2448-2454.
28. Lu, J., Le, Y., Ficolins and the fibrinogen-like domain. Immunobiology 1998, 199, 190-199.
29. Ma, Y. G., Cho, M. Y., Zhao, M., Park, J. W. et al., Human mannose-binding lectin and L-ficolin function as specific pattern recognition proteins in the lectin activation pathway of complement. J. Biol. Chem. 2004, 279, 25307-25312.
30. Hoeflich, C., Unterwalder, N., Schuett, S., Schmolke, K. et al., Clinical manifestation of mannose-binding lectin deficiency in adults independent of concomitant immunodeficiency. Hum. Immunol. 2009, 70, 809-812.
31. Brouwer, N., Frakking, F. N., van de Wetering, M. D., van Houdt, M. et al., Mannose-binding lectin (MBL) substitution: recovery of opsonic function in vivo lags behind MBL serum levels. J. Immunol. 2009, 183, 3496-3504.
32. Cedzynski, M., Atkinson, A. P., St Swierzko, A., MacDonald, S. L. et al., L-ficolin (ficolin-2) insufficiency is associated with combined allergic and infectious respiratory disease in children. Mol. Immunol. 2009, 47, 415-419.
33. Krarup, A., Thiel, S., Hansen, A., Fujita, T., Jensenius, J. C., L-ficolin is a pattern recognition molecule specific for acetyl groups. J. Biol. Chem. 2004, 279, 47513-47519.
34. Rabb, H., Agosti, S. J., Bittle, P. A., Fernandez, M. et al., Alterations in soluble and leukocyte surface L-selectin (CD 62L) in hemodialysis patients. J. Am. Soc. Nephrol. 1995, 6, 1445-1450.
35. Rosen, S. D., Ligands for L-selectin: homing, inflammation, and beyond. Annu. Rev. Immunol. 2004, 22, 129-156.
36. Pavalko, F. M., Walker, D. M., Graham, L., Goheen, M. et al., The cytoplasmic domain of L-selectin interacts with cytoskeletal proteins via alpha-actinin: receptor positioning in microvilli does not require interaction with alpha-actinin. J. Cell. Biol. 1995, 129, 1155-1164.
37. Yuruker, B., Niggli, V., Alpha-actinin and vinculin in human neutrophils: reorganization during adhesion and relation to the actin network. J. Cell Sci. 1992, 101, 403-414.