메뉴 건너뛰기




Volumn 6, Issue 5, 2012, Pages 542-552

Genotoxic stress modulates CDC25C phosphatase alternative splicing in human breast cancer cell lines

Author keywords

Alternative splicing; ATM; ATR; Breast cancer cells; CDC25; CDC25 phosphatases; CDK; CPT; DAPI; Dox; DSB; Eto; Genotoxic stress; HnRNP; PARP; PFT ; SR

Indexed keywords

CAMPTOTHECIN; CISPLATIN; DOXORUBICIN; ETOPOSIDE; MESSENGER RNA; PHOSPHATASE; PHOSPHATASE CDC25C; UNCLASSIFIED DRUG;

EID: 84866006890     PISSN: 15747891     EISSN: 18780261     Source Type: Journal    
DOI: 10.1016/j.molonc.2012.06.003     Document Type: Article
Times cited : (19)

References (49)
  • 1
    • 80054965134 scopus 로고    scopus 로고
    • Differential expression of CDC25 phosphatases splice variants in human breast cancer cells
    • Albert H., Santos S., Battaglia E., Brito M., Monteiro C., Bagrel D. Differential expression of CDC25 phosphatases splice variants in human breast cancer cells. Clin. Chem. Lab. Med. 2011, 49:1707-1714.
    • (2011) Clin. Chem. Lab. Med. , vol.49 , pp. 1707-1714
    • Albert, H.1    Santos, S.2    Battaglia, E.3    Brito, M.4    Monteiro, C.5    Bagrel, D.6
  • 2
  • 3
    • 0030919764 scopus 로고    scopus 로고
    • Alternative splicing of the human CDC25B tyrosine phosphatase. Possible implications for growth control?
    • Baldin V., Cans C., Superti-Furga G., Ducommun B. Alternative splicing of the human CDC25B tyrosine phosphatase. Possible implications for growth control?. Oncogene 1997, 14:2485-2495.
    • (1997) Oncogene , vol.14 , pp. 2485-2495
    • Baldin, V.1    Cans, C.2    Superti-Furga, G.3    Ducommun, B.4
  • 4
    • 0025367297 scopus 로고
    • Genetic and immochemical analysis of mutant p53 in human breast cancer cell lines
    • Bartek J., Iggo R., Gannon J., Lane D.P. Genetic and immochemical analysis of mutant p53 in human breast cancer cell lines. Oncogene 1990, 5:893-899.
    • (1990) Oncogene , vol.5 , pp. 893-899
    • Bartek, J.1    Iggo, R.2    Gannon, J.3    Lane, D.P.4
  • 7
    • 34250865564 scopus 로고    scopus 로고
    • CDC25 phosphatases in cancer cells: key players? Good targets?
    • Boutros R., Lobjois V., Ducommun B. CDC25 phosphatases in cancer cells: key players? Good targets?. Nat. Rev. Cancer 2007, 7:495-507.
    • (2007) Nat. Rev. Cancer , vol.7 , pp. 495-507
    • Boutros, R.1    Lobjois, V.2    Ducommun, B.3
  • 8
    • 0034543444 scopus 로고    scopus 로고
    • An additional transcript of the cdc25C gene from A431 cells encodes a functional protein
    • Bureik M., Rief N., Drescher R., Jungbluth A., Montenarh M., Wagner P. An additional transcript of the cdc25C gene from A431 cells encodes a functional protein. Int. J. Oncol. 2000, 17:1251-1258.
    • (2000) Int. J. Oncol. , vol.17 , pp. 1251-1258
    • Bureik, M.1    Rief, N.2    Drescher, R.3    Jungbluth, A.4    Montenarh, M.5    Wagner, P.6
  • 9
    • 77957306054 scopus 로고    scopus 로고
    • An emerging role for nuclear RNA-mediated responses to genotoxic stress
    • Busà R., Sette C. An emerging role for nuclear RNA-mediated responses to genotoxic stress. RNA Biol. 2010, 7:390-396.
    • (2010) RNA Biol. , vol.7 , pp. 390-396
    • Busà, R.1    Sette, C.2
  • 11
    • 33750378188 scopus 로고    scopus 로고
    • Genotoxic stress induces coordinately regulated alternative splicing of the p53 modulators MDM2 and MDM4
    • Chandler D.S., Singh R.K., Caldwell L.C., Bitler J.L., Lozano G. Genotoxic stress induces coordinately regulated alternative splicing of the p53 modulators MDM2 and MDM4. Cancer Res. 2006, 66:9502-9508.
    • (2006) Cancer Res. , vol.66 , pp. 9502-9508
    • Chandler, D.S.1    Singh, R.K.2    Caldwell, L.C.3    Bitler, J.L.4    Lozano, G.5
  • 12
    • 70350569286 scopus 로고    scopus 로고
    • Mechanisms of alternative splicing regulation: insights from molecular and genomics approaches
    • Chen M., Manley J.L. Mechanisms of alternative splicing regulation: insights from molecular and genomics approaches. Nat. Rev. Mol. Cell. Biol. 2009, 10:741-754.
    • (2009) Nat. Rev. Mol. Cell. Biol. , vol.10 , pp. 741-754
    • Chen, M.1    Manley, J.L.2
  • 14
    • 79955847712 scopus 로고    scopus 로고
    • Cdc25B is negatively regulated by p53 through Sp1 and NF-Y transcription factors
    • Dalvai M., Mondesert O., Bourdon J.-C., Ducommun B., Dozier C. Cdc25B is negatively regulated by p53 through Sp1 and NF-Y transcription factors. Oncogene 2011, 30:2282-2288.
    • (2011) Oncogene , vol.30 , pp. 2282-2288
    • Dalvai, M.1    Mondesert, O.2    Bourdon, J.-C.3    Ducommun, B.4    Dozier, C.5
  • 15
    • 63249088044 scopus 로고    scopus 로고
    • Dual regulation of Cdc25A by Chk1 and p53-ATF3 in DNA replication checkpoint control
    • Demidova A.R., Aau M.Y., Zhuang L., Yu Q. Dual regulation of Cdc25A by Chk1 and p53-ATF3 in DNA replication checkpoint control. J. Biol. Chem. 2009, 284:4132-4139.
    • (2009) J. Biol. Chem. , vol.284 , pp. 4132-4139
    • Demidova, A.R.1    Aau, M.Y.2    Zhuang, L.3    Yu, Q.4
  • 17
    • 34548045983 scopus 로고    scopus 로고
    • The early response to DNA damage can lead to activation of alternative splicing activity resulting in CD44 splice pattern changes
    • Filippov V., Filippova M., Duerksen-Hughes P.J. The early response to DNA damage can lead to activation of alternative splicing activity resulting in CD44 splice pattern changes. Cancer Res. 2007, 67:7621-7630.
    • (2007) Cancer Res. , vol.67 , pp. 7621-7630
    • Filippov, V.1    Filippova, M.2    Duerksen-Hughes, P.J.3
  • 18
    • 46149105398 scopus 로고    scopus 로고
    • Splicing and splice factor SRp55 participate in the response to DNA damage by changing isoform ratios of target genes
    • Filippov V., Schmidt E.L., Filippova M., Duerksen-Hughes P.J. Splicing and splice factor SRp55 participate in the response to DNA damage by changing isoform ratios of target genes. Gene 2008, 420:34-41.
    • (2008) Gene , vol.420 , pp. 34-41
    • Filippov, V.1    Schmidt, E.L.2    Filippova, M.3    Duerksen-Hughes, P.J.4
  • 23
    • 70350504453 scopus 로고    scopus 로고
    • The DNA-damage response in human biology and disease
    • Jackson S.P., Bartek J. The DNA-damage response in human biology and disease. Nature 2009, 461:1071-1078.
    • (2009) Nature , vol.461 , pp. 1071-1078
    • Jackson, S.P.1    Bartek, J.2
  • 26
    • 33745001764 scopus 로고    scopus 로고
    • Cdc25: mechanisms of checkpoint inhibition and recovery
    • Karlsson-Rosenthal C., Millar J.B.A. Cdc25: mechanisms of checkpoint inhibition and recovery. Trends Cell. Biol. 2006, 16:285-292.
    • (2006) Trends Cell. Biol. , vol.16 , pp. 285-292
    • Karlsson-Rosenthal, C.1    Millar, J.B.A.2
  • 27
    • 37149041700 scopus 로고    scopus 로고
    • Differential mitotic degradation of the CDC25B phosphatase variants
    • Kieffer I., Lorenzo C., Dozier C., Schmitt E., Ducommun B. Differential mitotic degradation of the CDC25B phosphatase variants. Oncogene 2007, 26:7847-7858.
    • (2007) Oncogene , vol.26 , pp. 7847-7858
    • Kieffer, I.1    Lorenzo, C.2    Dozier, C.3    Schmitt, E.4    Ducommun, B.5
  • 30
  • 31
    • 45849130152 scopus 로고    scopus 로고
    • Identification and characterization of a novel Mdm2 splice variant acutely induced by the chemotherapeutic agents adriamycin and actinomycin D
    • Lents N.H., Wheeler L.W., Baldassare J.J., Dynlacht B.D. Identification and characterization of a novel Mdm2 splice variant acutely induced by the chemotherapeutic agents adriamycin and actinomycin D. Cell Cycle 2008, 7:1580-1586.
    • (2008) Cell Cycle , vol.7 , pp. 1580-1586
    • Lents, N.H.1    Wheeler, L.W.2    Baldassare, J.J.3    Dynlacht, B.D.4
  • 32
    • 77950961695 scopus 로고    scopus 로고
    • γH2AX: a sensitive molecular marker of DNA damage and repair
    • Mah L.-J., El-Osta A., Karagiannis T.C. γH2AX: a sensitive molecular marker of DNA damage and repair. Leukemia 2010, 24:679-686.
    • (2010) Leukemia , vol.24 , pp. 679-686
    • Mah, L.-J.1    El-Osta, A.2    Karagiannis, T.C.3
  • 33
    • 56149095484 scopus 로고    scopus 로고
    • HdmX transcripts decrease following genotoxic stress
    • Markey M., Berberich S.J. hdmX transcripts decrease following genotoxic stress. Oncogene 2008, 27:6657-6666.
    • (2008) Oncogene , vol.27 , pp. 6657-6666
    • Markey, M.1    Berberich, S.J.2
  • 37
    • 27644480747 scopus 로고    scopus 로고
    • Increased expression and activity of CDC25C phosphatase and an alternatively spliced variant in prostate cancer
    • Ozen M., Ittmann M. Increased expression and activity of CDC25C phosphatase and an alternatively spliced variant in prostate cancer. Clin. Cancer Res. 2005, 11:4701-4706.
    • (2005) Clin. Cancer Res. , vol.11 , pp. 4701-4706
    • Ozen, M.1    Ittmann, M.2
  • 40
    • 78650930370 scopus 로고    scopus 로고
    • The DNA damage response pathway regulates the alternative splicing of the apoptotic mediator Bcl-x
    • Shkreta L., Michelle L., Toutant J., Tremblay M.L., Chabot B. The DNA damage response pathway regulates the alternative splicing of the apoptotic mediator Bcl-x. J. Biol. Chem. 2010, 286:331-340.
    • (2010) J. Biol. Chem. , vol.286 , pp. 331-340
    • Shkreta, L.1    Michelle, L.2    Toutant, J.3    Tremblay, M.L.4    Chabot, B.5
  • 42
    • 0015762456 scopus 로고
    • Human cell line from a pleural effusion derived from a breast carcinoma
    • Soule H.D., Vasquez J., Long A., Albert S., Brennan M.A. Human cell line from a pleural effusion derived from a breast carcinoma. J. Natl. Cancer I 1973, 51:1409-1416.
    • (1973) J. Natl. Cancer I , vol.51 , pp. 1409-1416
    • Soule, H.D.1    Vasquez, J.2    Long, A.3    Albert, S.4    Brennan, M.A.5
  • 44
    • 57749084853 scopus 로고    scopus 로고
    • Overexpression of the dual specificity phosphatase, Cdc25C, confers sensitivity on tumor cells to doxorubicin-induced cell death
    • Varmeh S., Manfredi J.J. Overexpression of the dual specificity phosphatase, Cdc25C, confers sensitivity on tumor cells to doxorubicin-induced cell death. Mol. Cancer Ther. 2008, 7:3789-3799.
    • (2008) Mol. Cancer Ther. , vol.7 , pp. 3789-3799
    • Varmeh, S.1    Manfredi, J.J.2
  • 47
    • 77952484477 scopus 로고    scopus 로고
    • Overexpression of CDC25B, CDC25C and phospho-CDC25C (Ser216) in vulvar squamous cell carcinomas are associated with malignant features and aggressive cancer phenotypes
    • Wang Z., Trope C.G., Florenes V.A., Suo Z., Nesland J.M., Holm R. Overexpression of CDC25B, CDC25C and phospho-CDC25C (Ser216) in vulvar squamous cell carcinomas are associated with malignant features and aggressive cancer phenotypes. BMC Cancer 2010, 10:233.
    • (2010) BMC Cancer , vol.10 , pp. 233
    • Wang, Z.1    Trope, C.G.2    Florenes, V.A.3    Suo, Z.4    Nesland, J.M.5    Holm, R.6
  • 48
    • 0033646929 scopus 로고    scopus 로고
    • Alternative splicing in the regulatory region of the human phosphatases CDC25A and CDC25C
    • Wegener S., Hampe W., Herrmann D., Schaller H.C. Alternative splicing in the regulatory region of the human phosphatases CDC25A and CDC25C. Eur. J. Cell. Biol. 2000, 79:810-815.
    • (2000) Eur. J. Cell. Biol. , vol.79 , pp. 810-815
    • Wegener, S.1    Hampe, W.2    Herrmann, D.3    Schaller, H.C.4
  • 49
    • 0026795623 scopus 로고
    • Overexpression of p-glycoprotein and glutathione S-transferase pi in MCF-7 cells selected for vincristine resistance in vitro
    • Whelan R.D., Waring C.J., Wolf C.R., Hayes J.D., Hosking L.K., Hill B.T. Overexpression of p-glycoprotein and glutathione S-transferase pi in MCF-7 cells selected for vincristine resistance in vitro. Int. J. Cancer 1992, 52:241-246.
    • (1992) Int. J. Cancer , vol.52 , pp. 241-246
    • Whelan, R.D.1    Waring, C.J.2    Wolf, C.R.3    Hayes, J.D.4    Hosking, L.K.5    Hill, B.T.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.