메뉴 건너뛰기




Volumn 3 JAN, Issue , 2012, Pages

Role of aldo-keto reductase enzymes in mediating the timing of parturition

Author keywords

Aldo Keto Reductases; Myometrium; Parturition; Placenta; Pregnancy; Prostaglandin metabolism; Steroid metabolism

Indexed keywords

11 EPIPROSTAGLANDIN F2 ALPHA; 20 OXOSTEROID; 5BETA DIHYDROPROGESTERONE; ALDO KETO REDUCTASE; ALDO KETO REDUCTASE 1B1; ALDO KETO REDUCTASE 1C1; ALDO KETO REDUCTASE 1C2; ALDO KETO REDUCTASE 1C3; ALDO KETO REDUCTASE 1D1; ANDROSTENEDIONE; ESTRONE; GESTAGEN; INDOMETACIN; LIGAND; MIFEPRISTONE; OXIDOREDUCTASE; OXOSTEROID; OXYTOCIN; PROGESTERONE; PROSTAGLANDIN; PROSTAGLANDIN D2; PROSTAGLANDIN F2 ALPHA; PROSTAGLANDIN H2; PROSTAGLANDIN SYNTHASE; PROSTANOID F RECEPTOR; PROSTANOID RECEPTOR; STEROID 5BETA REDUCTASE; STEROID REDUCTASE; UNCLASSIFIED DRUG; UTERUS SPASMOLYTIC AGENT;

EID: 84866000363     PISSN: None     EISSN: 16639812     Source Type: Journal    
DOI: 10.3389/fphar.2011.00092     Document Type: Article
Times cited : (11)

References (62)
  • 1
    • 34248645660 scopus 로고    scopus 로고
    • The interaction of neuroactive steroids and GABA in the development of neuropsychiatric disorders in women
    • Amin,Z.,Mason,G. F.,Cavus,I.,Krystal, J. H., Rothman, D. L., and Epperson, C. N. (2006). The interaction of neuroactive steroids and GABA in the development of neuropsychiatric disorders in women. Pharmacol. Biochem. Behav. 84, 635-643.
    • (2006) Pharmacol. Biochem. Behav. , vol.84 , pp. 635-643
    • Amin, Z.1    Mason, G.F.2    Cavus, I.3    Krystal, J.H.4    Rothman, D.L.5    Epperson, C.N.6
  • 2
    • 45149125808 scopus 로고    scopus 로고
    • Estrogen and progesterone metabolism in the cervix during pregnancy and parturition
    • Andersson, S., Minjarez, D., Yost, N. P., and Word, R. A. (2008). Estrogen and progesterone metabolism in the cervix during pregnancy and parturition. J. Clin. Endocrinol. Metab. 93, 2366-2374.
    • (2008) J. Clin. Endocrinol. Metab. , vol.93 , pp. 2366-2374
    • Andersson, S.1    Minjarez, D.2    Yost, N.P.3    Word, R.A.4
  • 3
    • 0037904091 scopus 로고    scopus 로고
    • The effects of a progesterone metabolite, 5βdihydroprogesterone, on oxytocin receptor binding in human myometrial membranes
    • Astle, S., Khan, R. N., and Thornton, S. (2003). The effects of a progesterone metabolite, 5βdihydroprogesterone, on oxytocin receptor binding in human myometrial membranes. BJOG 110, 589-592.
    • (2003) BJOG , vol.110 , pp. 589-592
    • Astle, S.1    Khan, R.N.2    Thornton, S.3
  • 5
    • 77954182699 scopus 로고    scopus 로고
    • Differential expression of the enzymatic system controlling synthesis, metabolism, and transport of PGF2αin human fetal membranes
    • Breuiller-Fouché, M., Leroy, M. J., Dubois, O., Reinaud, P., Chissey, A., Qi, H., Germain, G., Fortier, M. A., and Charpigny, G. (2010). Differential expression of the enzymatic system controlling synthesis, metabolism, and transport of PGF2αin human fetal membranes. Biol. Reprod. 83, 155-162.
    • (2010) Biol. Reprod. , vol.83 , pp. 155-162
    • Breuiller-Fouché, M.1    Leroy, M.J.2    Dubois, O.3    Reinaud, P.4    Chissey, A.5    Qi, H.6    Germain, G.7    Fortier, M.A.8    Charpigny, G.9
  • 6
    • 0032608427 scopus 로고    scopus 로고
    • Prostaglandin receptors in lower segment myometrium during gestation and labor
    • Brodt-Eppley, J., and Myatt, L. (1999). Prostaglandin receptors in lower segment myometrium during gestation and labor. Obstet. Gynecol. 93, 89-93.
    • (1999) Obstet. Gynecol. , vol.93 , pp. 89-93
    • Brodt-Eppley, J.1    Myatt, L.2
  • 7
    • 0033461173 scopus 로고    scopus 로고
    • Non-genomic effects of progesterone on the signaling function of G protein-coupled receptors
    • Burger, K., Fahrenholz, F., and Gimpl, G. (1999). Non-genomic effects of progesterone on the signaling function of G protein-coupled receptors. FEBS Lett. 464, 25-29.
    • (1999) FEBS Lett , vol.464 , pp. 25-29
    • Burger, K.1    Fahrenholz, F.2    Gimpl, G.3
  • 8
    • 74449092601 scopus 로고    scopus 로고
    • Aldo-keto reductase 1C3 expression in MCF-7 cells reveals roles in steroid hormone and prostaglandin metabolism that may explain its over-expression in breast cancer
    • Byrns, M. C., Duan, L., Lee, S. H., Blair, I. A., and Penning, T. M. (2010). Aldo-keto reductase 1C3 expression in MCF-7 cells reveals roles in steroid hormone and prostaglandin metabolism that may explain its over-expression in breast cancer. J. Steroid Biochem. Mol. Biol. 118, 177-187.
    • (2010) J. Steroid Biochem. Mol. Biol. , vol.118 , pp. 177-187
    • Byrns, M.C.1    Duan, L.2    Lee, S.H.3    Blair, I.A.4    Penning, T.M.5
  • 9
    • 37349047898 scopus 로고    scopus 로고
    • An indomethacin analogue, N-(4chlorobenzoyl)-melatonin, is a selective inhibitor of aldo-keto reductase 1C3 (type 2 3α-HSD, type 517β-HSD, and prostaglandin F synthase), a potential target for the treatment of hormone dependent and hormone independent malignancies
    • Byrns, M. C., Steckelbroeck, S., and Penning, T. M. (2008). An indomethacin analogue, N-(4chlorobenzoyl)-melatonin, is a selective inhibitor of aldo-keto reductase 1C3 (type 2 3α-HSD, type 517β-HSD, and prostaglandin F synthase), a potential target for the treatment of hormone dependent and hormone independent malignancies. Biochem. Pharmacol. 75, 484-493.
    • (2008) Biochem. Pharmacol. , vol.75 , pp. 484-493
    • Byrns, M.C.1    Steckelbroeck, S.2    Penning, T.M.3
  • 10
    • 0035951661 scopus 로고    scopus 로고
    • Genomic organization of a human 5β-reductase and its pseudogene and substrate selectivity of the expressed enzyme
    • Charbonneau, A., and Luu-The, V. (2001). Genomic organization of a human 5β-reductase and its pseudogene and substrate selectivity of the expressed enzyme. Biochim. Biophys. Acta 1517, 228-235.
    • (2001) Biochim. Biophys. Acta , vol.1517 , pp. 228-235
    • Charbonneau, A.1    Luu-The, V.2
  • 11
    • 79952575594 scopus 로고    scopus 로고
    • Substrate specificity and inhibitor analyses of human steroid 5β-reductase (AKR1D1)
    • Chen, M., Drury, J. E., and Penning, T. M. (2011). Substrate specificity and inhibitor analyses of human steroid 5β-reductase (AKR1D1). Steroids 76, 484-490.
    • (2011) Steroids , vol.76 , pp. 484-490
    • Chen, M.1    Drury, J.E.2    Penning, T.M.3
  • 12
    • 47749090561 scopus 로고    scopus 로고
    • Crystal structure of human liver Δ4-3-ketosteroid 5β-reductase (AKR1D1) and implications for substrate binding and catalysis
    • Di Costanzo, L., Drury, J. E., Penning, T. M., and Christianson, D. W. (2008). Crystal structure of human liver Δ4-3-ketosteroid 5β-reductase (AKR1D1) and implications for substrate binding and catalysis. J. Biol. Chem. 283, 16830-16839.
    • (2008) J. Biol. Chem. , vol.283 , pp. 16830-16839
    • Di Costanzo, L.1    Drury, J.E.2    Penning, T.M.3    Christianson, D.W.4
  • 13
    • 0018348136 scopus 로고
    • 20α-Hydroxysteroid oxidoreductase activity and 20αdihydroprogesterone concentration in human placenta before and after parturition
    • Diaz-Zagoya, J. C., Wiest, W. G., and Arias, F. (1979). 20α-Hydroxysteroid oxidoreductase activity and 20αdihydroprogesterone concentration in human placenta before and after parturition. Am. J. Obstet. Gynecol. 133, 673-676.
    • (1979) Am. J. Obstet. Gynecol. , vol.133 , pp. 673-676
    • Diaz-Zagoya, J.C.1    Wiest, W.G.2    Arias, F.3
  • 14
    • 0034003541 scopus 로고    scopus 로고
    • Pregnancy and exogenous steroid treatments modulate the expression of relaxant EP2 and contractile FP receptors in the rat uterus
    • Dong, Y. L., and Yallampalli, C. (2000). Pregnancy and exogenous steroid treatments modulate the expression of relaxant EP2 and contractile FP receptors in the rat uterus. Biol. Reprod. 62, 533-539.
    • (2000) Biol. Reprod. , vol.62 , pp. 533-539
    • Dong, Y.L.1    Yallampalli, C.2
  • 15
    • 0001429526 scopus 로고    scopus 로고
    • Characteristics of a highly labile human type 5 17betahydroxysteroid dehydrogenase
    • Dufort, I., Rheault, P., Huang, X. F., Soucy, P., and Luu-The, V. (1999). Characteristics of a highly labile human type 5 17betahydroxysteroid dehydrogenase. Endocrinology 140, 568-574.
    • (1999) Endocrinology , vol.140 , pp. 568-574
    • Dufort, I.1    Rheault, P.2    Huang, X.F.3    Soucy, P.4    Luu-The, V.5
  • 16
    • 58149171909 scopus 로고    scopus 로고
    • Crystal structures of human Δ4-3ketosteroid 5β-reductase (AKR1D1) reveal the presence of an alternative binding site responsible for substrate inhibition
    • Faucher, F., Cantin, L., Luu-The, V., Labrie, F., and Breton, R. (2008). Crystal structures of human Δ4-3ketosteroid 5β-reductase (AKR1D1) reveal the presence of an alternative binding site responsible for substrate inhibition. Biochemistry 47, 13537-13546.
    • (2008) Biochemistry , vol.47 , pp. 13537-13546
    • Faucher, F.1    Cantin, L.2    Luu-The, V.3    Labrie, F.4    Breton, R.5
  • 17
    • 24344452135 scopus 로고    scopus 로고
    • Specific PGF2α receptor (FP) antagonism and human uterine contractility in vitro
    • Friel, A. M., O'Reilly, M. W., Sexton, D. J., and Morrison, J. J. (2005). Specific PGF2α receptor (FP) antagonism and human uterine contractility in vitro. BJOG 112, 1034-1042.
    • (2005) BJOG , vol.112 , pp. 1034-1042
    • Friel, A.M.1    O'Reilly, M.W.2    Sexton, D.J.3    Morrison, J.J.4
  • 19
    • 2642672840 scopus 로고    scopus 로고
    • Inhibition of oxytocin receptor function by direct binding of progesterone
    • Grazzini, E., Guillon, G., Mouillac, B., and Zingg, H. H. (1998). Inhibition of oxytocin receptor function by direct binding of progesterone. Nature 392, 509-512.
    • (1998) Nature , vol.392 , pp. 509-512
    • Grazzini, E.1    Guillon, G.2    Mouillac, B.3    Zingg, H.H.4
  • 20
    • 0025341976 scopus 로고
    • Cloning and prokaryotic expression of a biologically active human placental aldose reductase
    • Grundmann, U., Bohn, H., Obermeier, R., and Amann, E. (1990). Cloning and prokaryotic expression of a biologically active human placental aldose reductase. DNA Cell Biol. 9, 149-157.
    • (1990) DNA Cell Biol , vol.9 , pp. 149-157
    • Grundmann, U.1    Bohn, H.2    Obermeier, R.3    Amann, E.4
  • 21
    • 79957573421 scopus 로고    scopus 로고
    • Aldo-keto reductases AKR1C1 AKR1C2 and AKR1C3 may enhance progesterone metabolism in ovarian endometriosis
    • Hevir, N., Vouk, K., Sinkovec, J., Ribič-Pucelj, M., and Rižner, T. L. (2011). Aldo-keto reductases AKR1C1, AKR1C2 and AKR1C3 may enhance progesterone metabolism in ovarian endometriosis. Chem. Biol. Interact. 191, 217-226.
    • (2011) Chem. Biol. Interact. , vol.191 , pp. 217-226
    • Hevir, N.1    Vouk, K.2    Sinkovec, J.3    Ribič-Pucelj, M.4    Rižner, T.L.5
  • 24
    • 79959255971 scopus 로고    scopus 로고
    • Reduced progesterone metabolites in human late pregnancy
    • Hill, M., Pařízek, A., Kancheva, R., and Jirásek, J. E. (2011). Reduced progesterone metabolites in human late pregnancy. Physiol. Res. 60, 225-241.
    • (2011) Physiol. Res. , vol.60 , pp. 225-241
    • Hill, M.1    Pařízek, A.2    Kancheva, R.3    Jirásek, J.E.4
  • 25
    • 33847789469 scopus 로고    scopus 로고
    • Stress in pregnancy activates neurosteroid production in the fetal brain
    • Hirst, J. J., Yawno, T., Nguyen, P., and Walker, D. W. (2006). Stress in pregnancy activates neurosteroid production in the fetal brain. Neuroendocrinology 84, 264-274.
    • (2006) Neuroendocrinology , vol.84 , pp. 264-274
    • Hirst, J.J.1    Yawno, T.2    Nguyen, P.3    Walker, D.W.4
  • 26
    • 0032587134 scopus 로고    scopus 로고
    • Ovine prostaglandin F2α receptor: steroid influence on steady-state levels of luteal mRNA
    • Hoyer, P. B., Marion, S. L., Stine, I., Rueda,B. R.,Hamernik,D. L.,Regan, J. W., and Wise, M. E. (1999). Ovine prostaglandin F2α receptor: steroid influence on steady-state levels of luteal mRNA. Endocrine 10, 105-111.
    • (1999) Endocrine , vol.10 , pp. 105-111
    • Hoyer, P.B.1    Marion, S.L.2    Stine, I.3    Rueda, B.R.4    Hamernik, D.L.5    Regan, J.W.6    Wise, M.E.7
  • 27
    • 38049174518 scopus 로고    scopus 로고
    • Primary, secondary, and tertiary interventions to reduce the morbidity and mortality of preterm birth
    • Iams, J. D., Romero, R., Culhane, J. F., and Goldenberg, R. L. (2008). Primary, secondary, and tertiary interventions to reduce the morbidity and mortality of preterm birth. Lancet 371, 164-175.
    • (2008) Lancet , vol.371 , pp. 164-175
    • Iams, J.D.1    Romero, R.2    Culhane, J.F.3    Goldenberg, R.L.4
  • 28
    • 79958862747 scopus 로고    scopus 로고
    • Stereospecific reduction of 5β-reduced steroids by human ketosteroid reductases of the AKR (aldoketo reductase) superfamily: role of AKR1C1-AKR1C4 in the metabolism of testosterone and progesterone via the 5βreductase pathway
    • Jin, Y., Mesaros, A. C., Blair, I. A., and Penning, T. M. (2011). Stereospecific reduction of 5β-reduced steroids by human ketosteroid reductases of the AKR (aldoketo reductase) superfamily: role of AKR1C1-AKR1C4 in the metabolism of testosterone and progesterone via the 5βreductase pathway. Biochem. J. 437, 53-61.
    • (2011) Biochem. J. , vol.437 , pp. 53-61
    • Jin, Y.1    Mesaros, A.C.2    Blair, I.A.3    Penning, T.M.4
  • 31
    • 77950121941 scopus 로고    scopus 로고
    • Vaginal prostaglandin (PGE2 and PGF2α) for induction of labour at term
    • Kelly, A. J., Kavanagh, J., and Thomas, J. (2003). Vaginal prostaglandin (PGE2 and PGF2α) for induction of labour at term. Cochrane Database Syst. Rev. 7, CD003101.
    • (2003) Cochrane Database Syst. Rev. , vol.7
    • Kelly, A.J.1    Kavanagh, J.2    Thomas, J.3
  • 32
    • 0018627642 scopus 로고
    • In vitro inhibition of rat uterine contractility induced by 5α and 5β progestins
    • Kubli-Garfias, C., Medrano-Conde, L., Beyer, C., and Bondani, A. (1979). In vitro inhibition of rat uterine contractility induced by 5α and 5β progestins. Steroids, 34, 609-617.
    • (1979) Steroids , vol.34 , pp. 609-617
    • Kubli-Garfias, C.1    Medrano-Conde, L.2    Beyer, C.3    Bondani, A.4
  • 34
    • 55449101303 scopus 로고    scopus 로고
    • AKR1C1 and SRD5A1 messenger RNA expression at term in the human myometrium and chorioamniotic membranes
    • Lee, R. H., Stanczyk, F. Z., Stolz, A., Ji, Q., Yang, G., and Goodwin, T. M. (2008a). AKR1C1 and SRD5A1 messenger RNA expression at term in the human myometrium and chorioamniotic membranes. Am. J. Perinatol. 25, 577-582.
    • (2008) Am. J. Perinatol. , vol.25 , pp. 577-582
    • Lee, R.H.1    Stanczyk, F.Z.2    Stolz, A.3    Ji, Q.4    Yang, G.5    Goodwin, T.M.6
  • 35
    • 38849138921 scopus 로고    scopus 로고
    • Amniotic fluid prostaglandin concentrations increase before the onset of spontaneous labor at term
    • Lee, S. E., Romero, R., Park, I. S., Seong, H. S., Park, C. W., and Yoon, B. H. (2008b). Amniotic fluid prostaglandin concentrations increase before the onset of spontaneous labor at term. J. Matern. Fetal. Neonatal. Med. 21, 89-94.
    • (2008) J. Matern. Fetal. Neonatal. Med. , vol.21 , pp. 89-94
    • Lee, S.E.1    Romero, R.2    Park, I.S.3    Seong, H.S.4    Park, C.W.5    Yoon, B.H.6
  • 37
    • 0037737815 scopus 로고    scopus 로고
    • An aldose reductase with 20α-hydroxysteroid dehydrogenase activity is most likely the enzyme responsible for the production of prostaglandin F2αin the bovine endometrium
    • Madore, E., Harvey, N., Parent, J., Chapdelaine, P., Arosh, J. A., and Fortier, M. A. (2003). An aldose reductase with 20α-hydroxysteroid dehydrogenase activity is most likely the enzyme responsible for the production of prostaglandin F2αin the bovine endometrium. J. Biol. Chem. 278, 11205-11212.
    • (2003) J. Biol. Chem. , vol.278 , pp. 11205-11212
    • Madore, E.1    Harvey, N.2    Parent, J.3    Chapdelaine, P.4    Arosh, J.A.5    Fortier, M.A.6
  • 38
    • 0031759084 scopus 로고    scopus 로고
    • Identification of a principal mRNA species for human 3α-hydroxysteroid dehydrogenase isoform (AKR1C3) that exhibits high prostaglandin D2 11-ketoreductase activity
    • Matsuura, K., Shiraishi, H., Hara, A., Sato, K., Deyashiki, Y., Ninomiya, M., and Sakai, S. (1998). Identification of a principal mRNA species for human 3α-hydroxysteroid dehydrogenase isoform (AKR1C3) that exhibits high prostaglandin D2 11-ketoreductase activity. J. Biochem. 124, 940-946.
    • (1998) J. Biochem. , vol.124 , pp. 940-946
    • Matsuura, K.1    Shiraishi, H.2    Hara, A.3    Sato, K.4    Deyashiki, Y.5    Ninomiya, M.6    Sakai, S.7
  • 39
    • 33947178092 scopus 로고    scopus 로고
    • Mifepristone and misoprostol in the induction of labor at term
    • McGill, J., and Shetty, A. (2007). Mifepristone and misoprostol in the induction of labor at term. Int. J. Gynaecol. Obstet. 96, 80-84.
    • (2007) Int. J. Gynaecol. Obstet. , vol.96 , pp. 80-84
    • McGill, J.1    Shetty, A.2
  • 40
    • 0032927426 scopus 로고    scopus 로고
    • Prostaglandin endoperoxide H synthase mRNA expression in the human amnion and decidua during pregnancy and in the amnion at preterm labour
    • Mijovic, J. E., Zakar, T., Angelova, J., and Olson, D. M. (1999). Prostaglandin endoperoxide H synthase mRNA expression in the human amnion and decidua during pregnancy and in the amnion at preterm labour. Mol. Hum. Reprod. 5, 182-187.
    • (1999) Mol. Hum. Reprod. , vol.5 , pp. 182-187
    • Mijovic, J.E.1    Zakar, T.2    Angelova, J.3    Olson, D.M.4
  • 41
    • 0017806420 scopus 로고
    • Initiation of human parturition IX. Progesterone metabolism by placentas of early and late human gestation
    • Milewich, L., Gant, N. F., Schwarz, B. E., Chen, G. T., and Macdonald, P. C. (1978). Initiation of human parturition. IX. Progesterone metabolism by placentas of early and late human gestation. Obstet. Gynecol. 51, 278-280.
    • (1978) Obstet. Gynecol. , vol.51 , pp. 278-280
    • Milewich, L.1    Gant, N.F.2    Schwarz, B.E.3    Chen, G.T.4    Macdonald, P.C.5
  • 43
    • 79953686781 scopus 로고    scopus 로고
    • Catalytic mechanism of the primary human prostaglandin F2α synthase, aldo-keto reductase 1B1 - prostaglandin D2 synthase activity in the absence of NADP(H)
    • Nagata, N., Kusakari, Y., Fukunishi, Y., Inoue, T., and Urade, Y. (2011). Catalytic mechanism of the primary human prostaglandin F2α synthase, aldo-keto reductase 1B1 - prostaglandin D2 synthase activity in the absence of NADP(H). FEBS J. 278, 1288-1298.
    • (2011) FEBS J , vol.278 , pp. 1288-1298
    • Nagata, N.1    Kusakari, Y.2    Fukunishi, Y.3    Inoue, T.4    Urade, Y.5
  • 44
    • 81255160733 scopus 로고    scopus 로고
    • Expression and localization of the 20α-hydroxysteroid dehydrogenase (HSD) enzyme in the reproductive tissues of the cynomolgus monkey Macaca fascicularis
    • Nanjidsuren, T., Naidansuren, P., Park, C. W., Park, J. J., Yun, S. J., Sim, B. W., Kang, M. H., Lee, S. R., Chang, K. T., and Min, K. S. (2011). Expression and localization of the 20α-hydroxysteroid dehydrogenase (HSD) enzyme in the reproductive tissues of the cynomolgus monkey Macaca fascicularis. J. Steroid Biochem. Mol. Biol. 127, 337-344.
    • (2011) J. Steroid Biochem. Mol. Biol. , vol.127 , pp. 337-344
    • Nanjidsuren, T.1    Naidansuren, P.2    Park, C.W.3    Park, J.J.4    Yun, S.J.5    Sim, B.W.6    Kang, M.H.7    Lee, S.R.8    Chang, K.T.9    Min, K.S.10
  • 45
    • 0034003544 scopus 로고    scopus 로고
    • Close kinship of human 20α-hydroxysteroid dehydrogenase gene with three aldoketo reductase genes
    • Nishizawa, M., Nakajima, T., Yasuda, K., Kanzaki, H., Sasaguri, Y., Watanabe, K., and Ito, S. (2000). Close kinship of human 20α-hydroxysteroid dehydrogenase gene with three aldoketo reductase genes. Genes Cells 5, 111-125.
    • (2000) Genes Cells , vol.5 , pp. 111-125
    • Nishizawa, M.1    Nakajima, T.2    Yasuda, K.3    Kanzaki, H.4    Sasaguri, Y.5    Watanabe, K.6    Ito, S.7
  • 46
    • 0141838129 scopus 로고    scopus 로고
    • Myometrial activation and preterm labour: evidence supporting a role for the prostaglandin F receptor- areview
    • Olson, D. M., Zaragoza, D. B., Shallow, M. C., Cook, J. L., Mitchell, B. F., Grigsby, P., and Hirst, J. (2003). Myometrial activation and preterm labour: evidence supporting a role for the prostaglandin F receptor- areview.Placenta 24(Suppl. A), S47-S54.
    • (2003) Placenta , vol.24 , Issue.SUPPL. A
    • Olson, D.M.1    Zaragoza, D.B.2    Shallow, M.C.3    Cook, J.L.4    Mitchell, B.F.5    Grigsby, P.6    Hirst, J.7
  • 47
    • 0034287545 scopus 로고    scopus 로고
    • Human 3αhydroxysteroid dehydrogenase isoforms (AKR1C1-AKR1C4) of the aldo-keto reductase superfamily: functional plasticity and tissue distribution reveals roles in the inactivation and formation of male and female sex hormones
    • Penning, T. M., Burczynski, M. E., Jez, J. M., Hung, C. F., Lin, H. K., Ma, H., Moore, M., Palackal, N., and Ratnam, K. (2000). Human 3αhydroxysteroid dehydrogenase isoforms (AKR1C1-AKR1C4) of the aldo-keto reductase superfamily: functional plasticity and tissue distribution reveals roles in the inactivation and formation of male and female sex hormones. Biochem. J. 351(Pt 1), 67-77.
    • (2000) Biochem. J. , vol.351 , Issue.PART 1 , pp. 67-77
    • Penning, T.M.1    Burczynski, M.E.2    Jez, J.M.3    Hung, C.F.4    Lin, H.K.5    Ma, H.6    Moore, M.7    Palackal, N.8    Ratnam, K.9
  • 48
    • 0025850517 scopus 로고
    • Inhibition of uterine contractility by progesterone and progesterone metabolites: mediation by progesterone and gamma amino butyric acidA receptor systems
    • Putnam, C. D., Brann, D. W., Kolbeck, R. C., and Mahesh, V. (1991). Inhibition of uterine contractility by progesterone and progesterone metabolites: mediation by progesterone and gamma amino butyric acidA receptor systems. Biol. Reprod. 45, 266-272.
    • (1991) Biol. Reprod. , vol.45 , pp. 266-272
    • Putnam, C.D.1    Brann, D.W.2    Kolbeck, R.C.3    Mahesh, V.4
  • 49
    • 78649361562 scopus 로고    scopus 로고
    • Neurosteroids: endogenous role in the human brain and therapeutic potentials. Prog
    • Reddy, D. S. (2010). Neurosteroids: endogenous role in the human brain and therapeutic potentials. Prog. Brain Res. 186, 113-137.
    • (2010) Brain Res , vol.186 , pp. 113-137
    • Reddy, D.S.1
  • 50
    • 33645356692 scopus 로고    scopus 로고
    • A possible role for progesterone metabolites in human parturition
    • Sheehan, P. M. (2006). A possible role for progesterone metabolites in human parturition. Aust. N. Z. J. Obstet. Gynaecol. 46, 159-163.
    • (2006) Aust. N. Z. J. Obstet. Gynaecol. , vol.46 , pp. 159-163
    • Sheehan, P.M.1
  • 51
    • 24344456508 scopus 로고    scopus 로고
    • 5β-dihydroprogesterone and steroid 5β-reductase decrease in association with human parturition at term
    • Sheehan, P. M., Rice, G. E., Moses, E. K., and Brennecke, S. P. (2005). 5β-dihydroprogesterone and steroid 5β-reductase decrease in association with human parturition at term. Mol. Hum. Reprod. 11, 495-501.
    • (2005) Mol. Hum. Reprod. , vol.11 , pp. 495-501
    • Sheehan, P.M.1    Rice, G.E.2    Moses, E.K.3    Brennecke, S.P.4
  • 52
    • 0032938845 scopus 로고    scopus 로고
    • Expression of cyclo-oxygenase types-1 and -2 in human fetal membranes throughout pregnancy
    • Slater,D.,Dennes,W.,Sawdy,R.,Allport, V., and Bennett, P. (1999). Expression of cyclo-oxygenase types-1 and -2 in human fetal membranes throughout pregnancy. J. Mol. Endocrinol. 22, 125-130.
    • (1999) J. Mol. Endocrinol. , vol.22 , pp. 125-130
    • Slater, D.1    Dennes, W.2    Sawdy, R.3    Allport, V.4    Bennett, P.5
  • 53
    • 33846456301 scopus 로고    scopus 로고
    • Parturition
    • Smith, R. (2007). Parturition. N. Engl. J. Med. 356, 271-283.
    • (2007) N. Engl. J. Med , vol.356 , pp. 271-283
    • Smith, R.1
  • 54
    • 80054072295 scopus 로고    scopus 로고
    • Enzymes of the cyclooxygenase pathways of prostanoid biosynthesis
    • Smith, W. L., Urade, Y., and Jakobsson, P. J. (2011). Enzymes of the cyclooxygenase pathways of prostanoid biosynthesis. Chem. Rev. 111, 5821-5865.
    • (2011) Chem. Rev. , vol.111 , pp. 5821-5865
    • Smith, W.L.1    Urade, Y.2    Jakobsson, P.J.3
  • 55
    • 18844369302 scopus 로고    scopus 로고
    • Role of aldose reductase and oxidative damage in diabetes and the consequent potential for therapeutic options
    • Srivastava, S. K., Ramana, K. V., and Bhatnagar, A. (2005). Role of aldose reductase and oxidative damage in diabetes and the consequent potential for therapeutic options. Endocr. Rev. 26, 380-392.
    • (2005) Endocr. Rev. , vol.26 , pp. 380-392
    • Srivastava, S.K.1    Ramana, K.V.2    Bhatnagar, A.3
  • 56
    • 1642305724 scopus 로고    scopus 로고
    • Human cytosolic 3α-hydroxysteroid dehydrogenases of the aldo-keto reductase superfamily display significant 3β-hydroxysteroid dehydrogenase activity: implications for steroid hormone metabolism and action
    • Steckelbroeck, S., Jin, Y., Gopishetty, S., Oyesanmi, B., and Penning, T. M. (2004). Human cytosolic 3α-hydroxysteroid dehydrogenases of the aldo-keto reductase superfamily display significant 3β-hydroxysteroid dehydrogenase activity: implications for steroid hormone metabolism and action. J. Biol. Chem. 279, 10784-10795.
    • (2004) J. Biol. Chem. , vol.279 , pp. 10784-10795
    • Steckelbroeck, S.1    Jin, Y.2    Gopishetty, S.3    Oyesanmi, B.4    Penning, T.M.5
  • 59
    • 0033577444 scopus 로고    scopus 로고
    • Progesterone metabolite and spontaneous myometrial contractions in vitro
    • Thornton, S., Terzidou, V., Clark, A., and Blanks, A. (1999). Progesterone metabolite and spontaneous myometrial contractions in vitro. Lancet 353, 1327-1329.
    • (1999) Lancet , vol.353 , pp. 1327-1329
    • Thornton, S.1    Terzidou, V.2    Clark, A.3    Blanks, A.4
  • 60
    • 74549165963 scopus 로고    scopus 로고
    • Lack of functional and expression homology between human and mouse aldoketo reductase 1C enzymes: implications for modelling human cancers
    • Veliça, P., Davies, N. J., Rocha, P. P., Schrewe, H., Ride, J. P., and Bunce, C. M. (2009). Lack of functional and expression homology between human and mouse aldoketo reductase 1C enzymes: implications for modelling human cancers. Mol. Cancer 8, 121.
    • (2009) Mol. Cancer , vol.8 , pp. 121
    • Veliça, P.1    Davies, N.J.2    Rocha, P.P.3    Schrewe, H.4    Ride, J.P.5    Bunce, C.M.6
  • 61
    • 82955194895 scopus 로고    scopus 로고
    • Recent reports about enzymes related to the synthesis of prostaglandin (PG) F2 (PGF2α and 9α 11β-PGF2)
    • Watanabe, K. (2011). Recent reports about enzymes related to the synthesis of prostaglandin (PG) F2 (PGF2α and 9α,11β-PGF2). J. Biochem. 150, 593-596.
    • (2011) J. Biochem. , vol.150 , pp. 593-596
    • Watanabe, K.1
  • 62
    • 34047173460 scopus 로고    scopus 로고
    • Progesterone withdrawal: key to parturition
    • Zakar, T., and Hertelendy, F. (2007). Progesterone withdrawal: key to parturition. Am. J. Obstet. Gynecol. 196, 289-296.
    • (2007) Am. J. Obstet. Gynecol. , vol.196 , pp. 289-296
    • Zakar, T.1    Hertelendy, F.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.