Progesterone metabolite and spontaneous myometrial contractions in vitro

Lancet

Volumn 353, Issue 9161, 1999, Pages 1327-1329

  Thornton, S ^a,b   Terzidou, V ^a,b   Clark, A ^a,b   Blanks, A ^a,b  

^a UNIVERSITY OF WARWICK   (United Kingdom)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

OXYTOCIN; OXYTOCIN ANTAGONIST; OXYTOCIN RECEPTOR; PROGESTERONE;

ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; FEMALE; HUMAN; HUMAN TISSUE; LABOR; METABOLITE; PREMATURE LABOR; PRIORITY JOURNAL; RECEPTOR BINDING; UTERUS CONTRACTION;

EID: 0033577444     PISSN: 01406736     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0140-6736(98)05247-7     Document Type: Article

References (5)

1. Kimura T, Takemura M, Nomura S, et al. Expression of oxytocin receptor in human pregnant myometrium. Endocrinol 1996; 137: 780-85.
2. Grazzini E, Guillon G, Mouillac B, Zingg HH. Inhibition of oxytocin receptor function by direct binding of progesterone. Nature 1998; 392:509-12.
3. Kumar D, Goodno JA, Barnes AC. Studies in human myometrium during pregnancy. IV: In vitro progesterone-oxytocin relationship. Am J Obstet Gynecol 1962; 84: 1111-15.
4. Löfgren M, Holst J, Bäckström T. Effects in vitro of progesterone and two 5α-reduced progestins, 5α-pregnane-3,20-dione and 5α-pregnane-3α-ol-20-one, on contracting human myometrium at term. Acta Obstet Gynecol Scand 1992; 71: 28-33.
5. Junkermann H, Runnebaum B, Lisboa BP. New progesterone metabolites in human myometrium. Steroids 1977; 30: 1-14.