메뉴 건너뛰기




Volumn 88, Issue 5, 2012, Pages 1165-1172

Resveratrol-mediated downregulation of rictor attenuates autophagic process and suppresses UV-induced skin carcinogenesis

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; CARRIER PROTEIN; LIGHT CHAIN 3, HUMAN; LYSOSOME ASSOCIATED MEMBRANE PROTEIN 2; MICROTUBULE ASSOCIATED PROTEIN; MULTIPROTEIN COMPLEX; RESVERATROL; RICTOR PROTEIN, MOUSE; STILBENE DERIVATIVE; TARGET OF RAPAMYCIN KINASE; TOR COMPLEX 2; TUMOR MARKER;

EID: 84865957147     PISSN: 00318655     EISSN: 17511097     Source Type: Journal    
DOI: 10.1111/j.1751-1097.2012.01097.x     Document Type: Conference Paper
Times cited : (54)

References (59)
  • 1
    • 0033256049 scopus 로고    scopus 로고
    • Environmental factors in nonmelanoma and melanoma skin cancer
    • Woodhead, A. D., R. B. Setlow, and, M. Tanaka, (1999) Environmental factors in nonmelanoma and melanoma skin cancer. J. Epidemiol. 9, S102-S114.
    • (1999) J. Epidemiol. , vol.9
    • Woodhead, A.D.1    Setlow, R.B.2    Tanaka, M.3
  • 2
    • 0035066054 scopus 로고    scopus 로고
    • The Hedgehog signalling pathway and cancer
    • DOI 10.1002/1096-9896(2000)9999:9999<::AID-PATH815>3.0.CO;2-N
    • Saldanha, G., (2001) The Hedgehog signalling pathway and cancer. J. Pathol. 193, 427-432. (Pubitemid 32266810)
    • (2001) Journal of Pathology , vol.193 , Issue.4 , pp. 427-432
    • Saldanha, G.1
  • 3
    • 0028886573 scopus 로고
    • Ultraviolet-B-light-induced mutagenesis of C-H-ras codons 11 and 12 in human skin fibroblasts
    • Amstad, P. A., and, P. A. Cerutti, (1995) Ultraviolet-B-light-induced mutagenesis of C-H-ras codons 11 and 12 in human skin fibroblasts. Int. J. Cancer 63, 136-139.
    • (1995) Int. J. Cancer , vol.63 , pp. 136-139
    • Amstad, P.A.1    Cerutti, P.A.2
  • 4
    • 32444433056 scopus 로고    scopus 로고
    • Cellular aspects of photocarcinogenesis
    • DOI 10.1039/b507471a
    • Nishigori, C., (2006) Cellular aspects of photocarcinogenesis. Photochem. Photobiol. Sci. 5, 208-214. (Pubitemid 43228049)
    • (2006) Photochemical and Photobiological Sciences , vol.5 , Issue.2 , pp. 208-214
    • Nishigori, C.1
  • 6
    • 33745245286 scopus 로고    scopus 로고
    • Everolimus (RAD) inhibits in vivo growth of murine squamous cell carcinoma (SCC VII)
    • DOI 10.1097/01.mlg.0000210544.64659.35, PII 0000553720060500000024
    • Khariwala, S. S., J. Kjaergaard, R. Lorenz, F. Van Lente, S. Shu, and, M. Strome, (2006) Everolimus (RAD) inhibits in vivo growth of murine squamous cell carcinoma (SCC VII). Laryngoscope 116, 814-820. (Pubitemid 44318043)
    • (2006) Laryngoscope , vol.116 , Issue.5 , pp. 814-820
    • Khariwala, S.S.1    Kjaergaard, J.2    Lorenz, R.3    Van Lente, F.4    Shu, S.5    Strome, M.6
  • 7
    • 84856228512 scopus 로고    scopus 로고
    • Mammalian target of rapamycin (mTOR) inhibitors slow skin carcinogenesis, but impair wound healing
    • Feldmeyer, L., G. F. Hofbauer, T. Boni, L. E. French, and, J. Hafner, (2012) Mammalian target of rapamycin (mTOR) inhibitors slow skin carcinogenesis, but impair wound healing. Br. J. Dermatol. 166, 422-424.
    • (2012) Br. J. Dermatol. , vol.166 , pp. 422-424
    • Feldmeyer, L.1    Hofbauer, G.F.2    Boni, T.3    French, L.E.4    Hafner, J.5
  • 8
    • 77951242363 scopus 로고    scopus 로고
    • Immunosuppressive cyclosporin A activates AKT in keratinocytes through PTEN suppression: Implications in skin carcinogenesis
    • Han, W., M. Ming, T. C. He, and, Y. Y. He, (2010) Immunosuppressive cyclosporin A activates AKT in keratinocytes through PTEN suppression: implications in skin carcinogenesis. J. Biol. Chem. 285, 11369-11377.
    • (2010) J. Biol. Chem. , vol.285 , pp. 11369-11377
    • Han, W.1    Ming, M.2    He, T.C.3    He, Y.Y.4
  • 9
    • 59649130340 scopus 로고    scopus 로고
    • The role of mTOR inhibitors in the management of posttransplant malignancy
    • Monaco, A. P., (2009) The role of mTOR inhibitors in the management of posttransplant malignancy. Transplantation 87, 157-163.
    • (2009) Transplantation , vol.87 , pp. 157-163
    • Monaco, A.P.1
  • 10
    • 53749099885 scopus 로고    scopus 로고
    • Skin cancer in organ transplant recipients - Where do we stand today?
    • Ulrich, C., J. Kanitakis, E. Stockfleth, and, S. Euvrard, (2008) Skin cancer in organ transplant recipients - where do we stand today? Am. J. Transplant. 8, 2192-2198.
    • (2008) Am. J. Transplant. , vol.8 , pp. 2192-2198
    • Ulrich, C.1    Kanitakis, J.2    Stockfleth, E.3    Euvrard, S.4
  • 12
    • 0034644525 scopus 로고    scopus 로고
    • TOR, a central controller of cell growth
    • Schmelzle, T., and, M. N. Hall, (2000) TOR, a central controller of cell growth. Cell 103, 253-262.
    • (2000) Cell , vol.103 , pp. 253-262
    • Schmelzle, T.1    Hall, M.N.2
  • 14
    • 33645944960 scopus 로고    scopus 로고
    • Autophagy and cancer therapy
    • Kondo, Y., and, S. Kondo, (2006) Autophagy and cancer therapy. Autophagy 2, 85-90.
    • (2006) Autophagy , vol.2 , pp. 85-90
    • Kondo, Y.1    Kondo, S.2
  • 15
    • 8344242220 scopus 로고    scopus 로고
    • Autophagy in health and disease: A double-edged sword
    • DOI 10.1126/science.1099993
    • Shintani, T., and, D. J. Klionsky, (2004) Autophagy in health and disease: a double-edged sword. Science 306, 990-995. (Pubitemid 39482894)
    • (2004) Science , vol.306 , Issue.5698 , pp. 990-995
    • Shintani, T.1    Klionsky, D.J.2
  • 16
    • 79960917666 scopus 로고    scopus 로고
    • Autophagy as a mediator of chemotherapy-induced cell death in cancer
    • Notte, A., and, L. C. Leclere, (2011) Autophagy as a mediator of chemotherapy-induced cell death in cancer. Biochem. Pharmacol. 82, 427-434.
    • (2011) Biochem. Pharmacol. , vol.82 , pp. 427-434
    • Notte, A.1    Leclere, L.C.2
  • 17
    • 2642553881 scopus 로고    scopus 로고
    • Regulation of an ATG7-beclin 1 program of autophaglic cell death by caspase-8
    • DOI 10.1126/science.1096645
    • Yu, L., A. Alva, H. Su, P. Dutt, E. Freundt, S. Welsh, E. H. Baehrecke, and, M. J. Lenardo, (2004) Regulation of an ATG7-beclin 1 program of autophagic cell death by caspase-8. Science 304, 1500-1502. (Pubitemid 38720930)
    • (2004) Science , vol.304 , Issue.5676 , pp. 1500-1502
    • Yu, L.1    Alva, A.2    Su, H.3    Dutt, P.4    Freundt, E.5    Welsh, S.6    Baehrecke, E.H.7    Lenardo, M.J.8
  • 21
    • 67650252764 scopus 로고    scopus 로고
    • RAD001 (Everolimus) induces autophagy in acute lymphoblastic leukemia
    • Crazzolara, R., K. F. Bradstock, and, L. J. Bendall, (2009) RAD001 (Everolimus) induces autophagy in acute lymphoblastic leukemia. Autophagy 5, 727-728.
    • (2009) Autophagy , vol.5 , pp. 727-728
    • Crazzolara, R.1    Bradstock, K.F.2    Bendall, L.J.3
  • 23
    • 69049109766 scopus 로고    scopus 로고
    • Resveratrol and chemoprevention
    • Goswami, S. K., and, D. K. Das, (2009) Resveratrol and chemoprevention. Cancer Lett. 284, 1-6.
    • (2009) Cancer Lett. , vol.284 , pp. 1-6
    • Goswami, S.K.1    Das, D.K.2
  • 24
    • 6944250259 scopus 로고    scopus 로고
    • Role of resveratrol in prevention and therapy of cancer: Preclinical and clinical studies
    • Aggarwal, B. B., A. Bhardwaj, R. S. Aggarwal, N. P. Seeram, S. Shishodia, and, Y. Takada, (2004) Role of resveratrol in prevention and therapy of cancer: preclinical and clinical studies. Anticancer Res. 24, 2783-2840. (Pubitemid 39409568)
    • (2004) Anticancer Research , vol.24 , Issue.A5 , pp. 2783-2840
    • Aggarwal, B.B.1    Bhardwaj, A.2    Aggarwal, R.S.3    Seeram, N.P.4    Shishodia, S.5    Takada, Y.6
  • 25
    • 14744268831 scopus 로고    scopus 로고
    • Prevention of ultraviolet-B radiation damage by resveratrol in mouse skin is mediated via modulation in survivin
    • DOI 10.1562/2004-08-13-RA-274.1
    • Aziz, M. H., F. Afaq, and, N. Ahmad, (2005) Prevention of ultraviolet-B radiation damage by resveratrol in mouse skin is mediated via modulation in survivin. Photochem. Photobiol. 81, 25-31. (Pubitemid 40327556)
    • (2005) Photochemistry and Photobiology , vol.81 , Issue.1 , pp. 25-31
    • Aziz, M.H.1    Afaq, F.2    Ahmad, N.3
  • 26
    • 3142678185 scopus 로고    scopus 로고
    • Modulations of critical cell cycle regulatory events during chemoprevention of ultraviolet B-mediated responses by resveratrol in SKH-1 hairless mouse skin
    • DOI 10.1038/sj.onc.1207666
    • Reagan-Shaw, S., F. Afaq, M. H. Aziz, and, N. Ahmad, (2004) Modulations of critical cell cycle regulatory events during chemoprevention of ultraviolet B-mediated responses by resveratrol in SKH-1 hairless mouse skin. Oncogene 23, 5151-5160. (Pubitemid 38980348)
    • (2004) Oncogene , vol.23 , Issue.30 , pp. 5151-5160
    • Reagan-Shaw, S.1    Afaq, F.2    Aziz, M.H.3    Ahmad, N.4
  • 28
    • 79956331962 scopus 로고    scopus 로고
    • Cancer cell survival following DNA damage-mediated premature senescence is regulated by mammalian target of rapamycin (mTOR)-dependent inhibition of sirtuin 1
    • Back, J. H., H. R. Rezvani, Y. Zhu, V. Guyonnet-Duperat, M. Athar, D. Ratner, and, A. L. Kim, (2011) Cancer cell survival following DNA damage-mediated premature senescence is regulated by mammalian target of rapamycin (mTOR)-dependent inhibition of sirtuin 1. J. Biol. Chem. 286, 19100-19108.
    • (2011) J. Biol. Chem. , vol.286 , pp. 19100-19108
    • Back, J.H.1    Rezvani, H.R.2    Zhu, Y.3    Guyonnet-Duperat, V.4    Athar, M.5    Ratner, D.6    Kim, A.L.7
  • 29
    • 33748422079 scopus 로고    scopus 로고
    • Oncogene-induced cell senescence - Halting on the road to cancer
    • DOI 10.1056/NEJMra062285
    • Mooi, W. J., and, D. S. Peeper, (2006) Oncogene-induced cell senescence - halting on the road to cancer. N. Engl. J. Med. 355, 1037-1046. (Pubitemid 44343547)
    • (2006) New England Journal of Medicine , vol.355 , Issue.10 , pp. 1037-1046
    • Mooi, W.J.1    Peeper, D.S.2
  • 30
    • 13944270339 scopus 로고    scopus 로고
    • Senescent cells, tumor suppression, and organismal aging: Good citizens, bad neighbors
    • DOI 10.1016/j.cell.2005.02.003
    • Campisi, J., (2005) Senescent cells, tumor suppression, and organismal aging: good citizens, bad neighbors. Cell 120, 513-522. (Pubitemid 40269765)
    • (2005) Cell , vol.120 , Issue.4 , pp. 513-522
    • Campisi, J.1
  • 31
    • 0042206639 scopus 로고    scopus 로고
    • Association of increased autophagic inclusions labeled for β-galactosidase with fibroblastic aging
    • DOI 10.1016/S0531-5565(03)00132-3
    • Gerland, L. M., S. Peyrol, C. Lallemand, R. Branche, J. P. Magaud, and, M. French, (2003) Association of increased autophagic inclusions labeled for beta-galactosidase with fibroblastic aging. Exp. Gerontol. 38, 887-895. (Pubitemid 36952670)
    • (2003) Experimental Gerontology , vol.38 , Issue.8 , pp. 887-895
    • Gerland, L.-M.1    Peyrol, S.2    Lallemand, C.3    Branche, R.4    Magaud, J.-P.5    Ffrench, M.6
  • 32
    • 23044466031 scopus 로고    scopus 로고
    • Quantitative assay of senescence-associated β-galactosidase activity in mammalian cell extracts
    • DOI 10.1016/j.ab.2005.06.003, PII S0003269705004185
    • Gary, R. K., and, S. M. Kindell, (2005) Quantitative assay of senescence-associated beta-galactosidase activity in mammalian cell extracts. Anal. Biochem. 343, 329-334. (Pubitemid 41074047)
    • (2005) Analytical Biochemistry , vol.343 , Issue.2 , pp. 329-334
    • Gary, R.K.1    Kindell, S.M.2
  • 33
    • 0036096532 scopus 로고    scopus 로고
    • Ultraviolet-B-induced G1 arrest is mediated by downregulation of cyclin-dependent kinase 4 in transformed keratinocytes lacking functional p53
    • DOI 10.1046/j.1523-1747.2002.01734.x
    • Kim, A. L., M. Athar, D. R. Bickers, and, J. Gautier, (2002) Ultraviolet-B-induced G1 arrest is mediated by downregulation of cyclin-dependent kinase 4 in transformed keratinocytes lacking functional p53. J. Invest. Dermatol. 118, 818-824. (Pubitemid 34526544)
    • (2002) Journal of Investigative Dermatology , vol.118 , Issue.5 , pp. 818-824
    • Kim, A.L.1    Athar, M.2    Bickers, D.R.3    Gautier, J.4
  • 34
    • 0036371926 scopus 로고    scopus 로고
    • Stage-specific alterations of cyclin expression during UVB-induced murine skin tumor development
    • Kim, A. L., M. Athar, D. R. Bickers, and, J. Gautier, (2002) Stage-specific alterations of cyclin expression during UVB-induced murine skin tumor development. Photochem. Photobiol. 75, 58-67.
    • (2002) Photochem. Photobiol. , vol.75 , pp. 58-67
    • Kim, A.L.1    Athar, M.2    Bickers, D.R.3    Gautier, J.4
  • 35
    • 63349098256 scopus 로고    scopus 로고
    • Inhibition of macroautophagy by bafilomycin A1 lowers proliferation and induces apoptosis in colon cancer cells
    • Wu, Y. C., W. K. Wu, Y. Li, L. Yu, Z. J. Li, C. C. Wong, H. T. Li, J. J. Sung, and, C. H. Cho, (2009) Inhibition of macroautophagy by bafilomycin A1 lowers proliferation and induces apoptosis in colon cancer cells. Biochem. Biophys. Res. Commun. 382, 451-456.
    • (2009) Biochem. Biophys. Res. Commun. , vol.382 , pp. 451-456
    • Wu, Y.C.1    Wu, W.K.2    Li, Y.3    Yu, L.4    Li, Z.J.5    Wong, C.C.6    Li, H.T.7    Sung, J.J.8    Cho, C.H.9
  • 36
    • 33947235679 scopus 로고    scopus 로고
    • Vincristine induces dramatic lysosomal changes and sensitizes cancer cells to lysosome-destabilizing siramesine
    • DOI 10.1158/0008-5472.CAN-06-3520
    • Groth-Pedersen, L., M. S. Ostenfeld, M. Hoyer-Hansen, J. Nylandsted, and, M. Jaattela, (2007) Vincristine induces dramatic lysosomal changes and sensitizes cancer cells to lysosome-destabilizing siramesine. Cancer Res. 67, 2217-2225. (Pubitemid 46424241)
    • (2007) Cancer Research , vol.67 , Issue.5 , pp. 2217-2225
    • Groth-Pedersen, L.1    Ostenfeld, M.S.2    Hoyer-Hansen, M.3    Nylandsted, J.4    Jaattela, M.5
  • 37
    • 33645120442 scopus 로고    scopus 로고
    • Microtubules facilitate autophagosome formation and fusion of autophagosomes with endosomes
    • Kochl, R., X. W. Hu, E. Y. Chan, and, S. A. Tooze, (2006) Microtubules facilitate autophagosome formation and fusion of autophagosomes with endosomes. Traffic 7, 129-145.
    • (2006) Traffic , vol.7 , pp. 129-145
    • Kochl, R.1    Hu, X.W.2    Chan, E.Y.3    Tooze, S.A.4
  • 38
    • 0034012322 scopus 로고    scopus 로고
    • Autophagic and apoptotic types of programmed cell death exhibit different fates of cytoskeletal filaments
    • Bursch, W., K. Hochegger, L. Torok, B. Marian, A. Ellinger, and, R. S. Hermann, (2000) Autophagic and apoptotic types of programmed cell death exhibit different fates of cytoskeletal filaments. J. Cell Sci. 113 (Pt 7), 1189-1198. (Pubitemid 30229536)
    • (2000) Journal of Cell Science , vol.113 , Issue.7 , pp. 1189-1198
    • Bursch, W.1    Hochegger, K.2    Torok, L.3    Marian, B.4    Ellinger, A.5    Hermann, R.S.6
  • 39
    • 28644447348 scopus 로고    scopus 로고
    • The actin cytoskeleton is required for selective types of autophagy, but not nonspecific autophagy, in the yeast Saccharomyces cerevisiae
    • DOI 10.1091/mbc.E05-07-0629
    • Reggiori, F., I. Monastyrska, T. Shintani, and, D. J. Klionsky, (2005) The actin cytoskeleton is required for selective types of autophagy, but not nonspecific autophagy, in the yeast Saccharomyces cerevisiae. Mol. Biol. Cell 16, 5843-5856. (Pubitemid 41752231)
    • (2005) Molecular Biology of the Cell , vol.16 , Issue.12 , pp. 5843-5856
    • Reggiori, F.1    Monastyrska, I.2    Shintani, T.3    Klionsky, D.J.4
  • 40
    • 63749119765 scopus 로고    scopus 로고
    • PIKKing on PKB: Regulation of PKB activity by phosphorylation
    • Bozulic, L., and, B. A. Hemmings, (2009) PIKKing on PKB: regulation of PKB activity by phosphorylation. Curr. Opin. Cell Biol. 21, 256-261.
    • (2009) Curr. Opin. Cell Biol. , vol.21 , pp. 256-261
    • Bozulic, L.1    Hemmings, B.A.2
  • 41
    • 15044350668 scopus 로고    scopus 로고
    • The expanding TOR signaling network
    • DOI 10.1016/j.ceb.2005.02.008, Cell Regulation
    • Martin, D. E., and, M. N. Hall, (2005) The expanding TOR signaling network. Curr. Opin. Cell Biol. 17, 158-166. (Pubitemid 40380939)
    • (2005) Current Opinion in Cell Biology , vol.17 , Issue.2 , pp. 158-166
    • Martin, D.E.1    Hall, M.N.2
  • 42
    • 27544500981 scopus 로고    scopus 로고
    • Growing roles for the mTOR pathway
    • DOI 10.1016/j.ceb.2005.09.009, PII S0955067405001481
    • Sarbassov, D. D., S. M. Ali, and, D. M. Sabatini, (2005) Growing roles for the mTOR pathway. Curr. Opin. Cell Biol. 17, 596-603. (Pubitemid 41540408)
    • (2005) Current Opinion in Cell Biology , vol.17 , Issue.6 , pp. 596-603
    • Sarbassov, D.D.1    Ali, S.M.2    Sabatini, D.M.3
  • 43
    • 13844312400 scopus 로고    scopus 로고
    • Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex
    • DOI 10.1126/science.1106148
    • Sarbassov, D. D., D. A. Guertin, S. M. Ali, and, D. M. Sabatini, (2005) Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex. Science 307, 1098-1101. (Pubitemid 40262113)
    • (2005) Science , vol.307 , Issue.5712 , pp. 1098-1101
    • Sarbassov, D.D.1    Guertin, D.A.2    Ali, S.M.3    Sabatini, D.M.4
  • 44
    • 7944235758 scopus 로고    scopus 로고
    • Mammalian TOR complex 2 controls the actin cytoskeleton and is rapamycin insensitive
    • DOI 10.1038/ncb1183
    • Jacinto, E., R. Loewith, A. Schmidt, S. Lin, M. A. Ruegg, A. Hall, and, M. N. Hall, (2004) Mammalian TOR complex 2 controls the actin cytoskeleton and is rapamycin insensitive. Nat. Cell Biol. 6, 1122-1128. (Pubitemid 39468014)
    • (2004) Nature Cell Biology , vol.6 , Issue.11 , pp. 1122-1128
    • Jacinto, E.1    Loewith, R.2    Schmidt, A.3    Lin, S.4    Ruegg, M.A.5    Hall, A.6    Hall, M.N.7
  • 45
    • 0036236006 scopus 로고    scopus 로고
    • The mitochondrial-lysosomal axis theory of aging: Accumulation of damaged mitochondria as a result of imperfect autophagocytosis
    • DOI 10.1046/j.1432-1033.2002.02869.x
    • Brunk, U. T., and, A. Terman, (2002) The mitochondrial-lysosomal axis theory of aging: accumulation of damaged mitochondria as a result of imperfect autophagocytosis. Eur. J. Biochem. 269, 1996-2002. (Pubitemid 34437840)
    • (2002) European Journal of Biochemistry , vol.269 , Issue.8 , pp. 1996-2002
    • Brunk, U.T.1    Terman, A.2
  • 46
    • 0042707790 scopus 로고    scopus 로고
    • Mitochondrial recycling and aging of cardiac myocytes: The role of autophagocytosis
    • DOI 10.1016/S0531-5565(03)00114-1
    • Terman, A., H. Dalen, J. W. Eaton, J. Neuzil, and, U. T. Brunk, (2003) Mitochondrial recycling and aging of cardiac myocytes: the role of autophagocytosis. Exp. Gerontol. 38, 863-876. (Pubitemid 36952668)
    • (2003) Experimental Gerontology , vol.38 , Issue.8 , pp. 863-876
    • Terman, A.1    Dalen, H.2    Eaton, J.W.3    Neuzil, J.4    Brunk, U.T.5
  • 47
    • 1642556763 scopus 로고    scopus 로고
    • Resveratrol-induced Autophagocytosis in Ovarian Cancer Cells
    • DOI 10.1158/0008-5472.CAN-03-2404
    • Opipari, A. W., L. Tan, A. E. Boitano, D. R. Sorenson, A. Aurora, and, J. R. Liu, (2004) Resveratrol-induced autophagocytosis in ovarian cancer cells. Cancer Res. 64, 696-703. (Pubitemid 38120912)
    • (2004) Cancer Research , vol.64 , Issue.2 , pp. 696-703
    • Opipari Jr., A.W.1    Tan, L.2    Boitano, A.E.3    Sorenson, D.R.4    Aurora, A.5    Liu, J.R.6
  • 48
    • 40549085336 scopus 로고    scopus 로고
    • Resveratrol-induced apoptosis depends on the lipid kinase activity of Vps34 and on the formation of autophagolysosomes
    • DOI 10.1093/carcin/bgm271
    • Trincheri, N. F., C. Follo, G. Nicotra, C. Peracchio, R. Castino, and, C. Isidoro, (2008) Resveratrol-induced apoptosis depends on the lipid kinase activity of Vps34 and on the formation of autophagolysosomes. Carcinogenesis 29, 381-389. (Pubitemid 351359678)
    • (2008) Carcinogenesis , vol.29 , Issue.2 , pp. 381-389
    • Trincheri, N.F.1    Follo, C.2    Nicotra, G.3    Peracchio, C.4    Castino, R.5    Isidoro, C.6
  • 53
    • 28844433954 scopus 로고    scopus 로고
    • Lovastatin-induced RhoA modulation and its effect on senescence in prostate cancer cells
    • DOI 10.1016/j.bbrc.2005.11.075, PII S0006291X05025970
    • Lee, J., I. Lee, C. Park, and, W. K. Kang, (2006) Lovastatin-induced RhoA modulation and its effect on senescence in prostate cancer cells. Biochem. Biophys. Res. Commun. 339, 748-754. (Pubitemid 41772877)
    • (2006) Biochemical and Biophysical Research Communications , vol.339 , Issue.3 , pp. 748-754
    • Lee, J.1    Lee, I.2    Park, C.3    Kang, W.K.4
  • 55
    • 37549048521 scopus 로고    scopus 로고
    • MTORC2 activity is elevated in gliomas and promotes growth and cell motility via overexpression of rictor
    • Masri, J., A. Bernath, J. Martin, O. D. Jo, R. Vartanian, A. Funk, and, J. Gera, (2007) mTORC2 activity is elevated in gliomas and promotes growth and cell motility via overexpression of rictor. Cancer Res. 67, 11712-11720.
    • (2007) Cancer Res. , vol.67 , pp. 11712-11720
    • Masri, J.1    Bernath, A.2    Martin, J.3    Jo, O.D.4    Vartanian, R.5    Funk, A.6    Gera, J.7
  • 56
    • 61649093766 scopus 로고    scopus 로고
    • To die or to live: The dual role of poly(ADP-ribose) polymerase-1 in autophagy and necrosis under oxidative stress and DNA damage
    • Huang, Q., and, H. M. Shen, (2009) To die or to live: the dual role of poly(ADP-ribose) polymerase-1 in autophagy and necrosis under oxidative stress and DNA damage. Autophagy 5, 273-276.
    • (2009) Autophagy , vol.5 , pp. 273-276
    • Huang, Q.1    Shen, H.M.2
  • 58
    • 33749185898 scopus 로고    scopus 로고
    • Autophagy as a cell-repair mechanism: Activation of chaperone-mediated autophagy during oxidative stress
    • DOI 10.1016/j.mam.2006.08.007, PII S0098299706000197
    • Kaushik, S., and, A. M. Cuervo, (2006) Autophagy as a cell-repair mechanism: activation of chaperone-mediated autophagy during oxidative stress. Mol. Aspects Med. 27, 444-454. (Pubitemid 44472625)
    • (2006) Molecular Aspects of Medicine , vol.27 , Issue.5-6 , pp. 444-454
    • Kaushik, S.1    Cuervo, A.M.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.