Synthesis and biological evaluation of novel benzimidazole derivatives and their binding behavior with bovine serum albumin

European Journal of Medicinal Chemistry

Volumn 55, Issue , 2012, Pages 164-175

  Zhang, Shao Lin ^a   Damu, Guri L V ^a,b   Zhang, Ling ^a   Geng, Rong Xia ^a   Zhou, Cheng He ^a  

^a SOUTHWEST UNIVERSITY   (China)

^b INDIAN INSTITUTE OF CHEMICAL TECHNOLOGY   (India)

Author keywords

Antibacterial; Antifungal; Benzimidazole; Fluorescence spectrum

Indexed keywords

2 (CHLOROMETHYL) 1H BENZOIMIDAZOLE; 3,4 DIMETHYLTHIOPHENE 2,5 DICARBOHYDRAZIDE; ANTIFUNGAL AGENT; ANTIINFECTIVE AGENT; BENZIMIDAZOLE DERIVATIVE; FLUCONAZOLE; N'2 [(1H BENZOIMIDAZOL 2 YL)METHYL] 3,4 DIMETHYLTHIOPHENE 2,5 DICARBOHYDRAZIDE; N'2,N'5 BIS[(1 DECYL 1H BENZOIMIDAZOL 2 YL)METHYL] 3,4 DIMETHYLTHIOPHENE 2,5 DICARBOHYDRAZIDE; N'2,N'5 BIS[(1 DECYL 1H BENZOIMIDAZOL 2 YL)METHYL] 3,4 DIMETHYLTHIOPHENE 2,5 DICARBOHYDRAZIDE HYDROCHLORIDE; N'2,N'5 BIS[(1 DODCYL 1H BENZOIMIDAZOL 2 YL)METHYL] 3,4 DIMETHYLTHIOPHENE 2,5 DICARBOHYDRAZIDE; N'2,N'5 BIS[(1 HEXYL 1H BENZOIMIDAZOL 2 YL)METHYL] 3,4 DIMETHYLTHIOPHENE 2,5 DICARBOHYDRAZIDE; N'2,N'5 BIS[(1 OCTADEYL 1H BENZOIMIDAZOL 2 YL)METHYL] 3,4 DIMETHYLTHIOPHENE 2,5 DICARBOHYDRAZIDE; N'2,N'5 BIS[(1 OCTYL 1H BENZOIMIDAZOL 2 YL)METHYL] 3,4 DIMETHYLTHIOPHENE 2,5 DICARBOHYDRAZIDE; N'2,N'5 BIS[(1 PROPYL 1H BENZOIMIDAZOL 2 YL)METHYL] 3,4 DIMETHYLTHIOPHENE 2,5 DICARBOHYDRAZIDE; N'2,N'5 BIS[(1 PROPYL 1H BENZOIMIDAZOL 2 YL)METHYL] 3,4 DIMETHYLTHIOPHENE 2,5 DICARBOHYDRAZIDE HYDROCHLORIDE; N'2,N'5 BIS[(1H BENZOIMIDAZOL 2 YL)METHYL] 3,4 DIMETHYLTHIOPHENE 2,5 DICARBOHYDRAZIDE; N'2,N'5 BIS[[1 (2 CHLOROBENZYL) 1H BENZOIMIDAZOLE 2 YL]METHYL] 3,4 DIMETHYLTHIOPHENE 2,5 DICARBOHYDRAZIDE; N'2,N'5 BIS[[1 (2,4 DIFLUOROBENZYL) 1H BENZOIMIDAZOLE 2 YL]METHYL] 3,4 DIMETHYLTHIOPHENE 2,5 DICARBOHYDRAZIDE; N'2,N'5 BIS[[1 (3 CHLOROBENZYL) 1H BENZOIMIDAZOLE 2 YL]METHYL] 3,4 DIMETHYLTHIOPHENE 2,5 DICARBOHYDRAZIDE; N'2,N'5 BIS[[1 (3,4 DICHLOROBENZYL) 1H BENZOIMIDAZOLE 2 YL]METHYL] 3,4 DIMETHYLTHIOPHENE 2,5 DICARBOHYDRAZIDE; N'2,N'5 BIS[[1 (4 CHLOROBENZYL) 1H BENZOIMIDAZOLE 2 YL]METHYL] 3,4 DIMETHYLTHIOPHENE 2,5 DICARBOHYDRAZIDE; N'2,N'5 BIS[[1 (4 FLUOROBENZYL) 1H BENZOIMIDAZOLE 2 YL]METHYL] 3,4 DIMETHYLTHIOPHENE 2,5 DICARB HYDRAZIDE; N'2,N'5 BIS[[1 (4 FLUOROBENZYL) 1H BENZOIMIDAZOLE 2 YL]METHYL] 3,4 DIMETHYLTHIOPHENE 2,5 DICARBO HYDRAZIDE HYDROCHLORIDE; NORFLOXACIN; SERUM ALBUMIN; UNCLASSIFIED DRUG;

ABSORPTION SPECTROSCOPY; ANTIFUNGAL ACTIVITY; ANTIMICROBIAL ACTIVITY; ARTICLE; BIOASSAY; CARBON NUCLEAR MAGNETIC RESONANCE; COW; DRUG SYNTHESIS; FLUORESCENCE SPECTROSCOPY; HYDROGEN BOND; INFRARED SPECTROPHOTOMETRY; MASS SPECTROMETRY; NONHUMAN; PROTON NUCLEAR MAGNETIC RESONANCE; SYNTHESIS; THERMODYNAMICS; ULTRAVIOLET SPECTROSCOPY;

ANIMALS; ANTI-INFECTIVE AGENTS; BACTERIA; BENZIMIDAZOLES; CATTLE; CHEMISTRY TECHNIQUES, SYNTHETIC; FUNGI; MICROBIAL SENSITIVITY TESTS; SERUM ALBUMIN, BOVINE; THERMODYNAMICS;

EID: 84865760149     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2012.07.015     Document Type: Article

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