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Volumn 19, Issue 6, 2011, Pages 2023-2029
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Synthesis and biological evaluation of benzimidazole-5-carbohydrazide derivatives as antimalarial, cytotoxic and antitubercular agents
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Author keywords
Hematin; Antimalarial; Benzimidazole; Cancer; Plasmodium berghei; Tuberculosis
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Indexed keywords
2 (5 NITROFURAN 2 YL) 3H BENZO[D]IMIDAZOLE 5 CARBOXYLIC ACID;
2 (5 NITROTHIOPHEN 2 YL) 3H BENZO[D]IMIDAZOLE 5 CARBOXYLIC ACID;
BENZIMIDAZOLE 5 CARBOHYDRAZIDE DERIVATIVE;
BENZIMIDAZOLE DERIVATIVE;
CHLOROQUINE;
CISPLATIN;
ISONIAZID;
LEUPEPTIN;
N' (3 CHLOROBENZOYL) 2 (5 NITROFURAN 2 YL) 3H BENZO[D]IMIDAZOLE 5 CARBOHYDRAZIDE;
N' (3 CHLOROBENZOYL) 2 (5 NITROTHIOPHEN 2 YL) 3H BENZO[D]IMIDAZOLE 5 CARBOHYDRAZIDE;
N' (3 HYDROXY 2 NAPHTHYL) 2 (5 NITROFURAN 2 YL) 3H BENZO[D]IMIDAZOLE 5 CARBOHYDRAZIDE;
N' (3 HYDROXY 2 NAPHTHYL) 2 (5 NITROTHIOPHEN 2 YL) 3H BENZO[D]IMIDAZOLE 5 CARBOHYDRAZIDE;
N' (3 METHOXYBENZOYL) 2 (5 NITROFURAN 2 YL) 3H BENZO[D]IMIDAZOLE 5 CARBOHYDRAZIDE;
N' (3 METHOXYBENZOYL) 2 (5 NITROTHIOPHEN 2 YL) 3H BENZO[D]IMIDAZOLE 5 CARBOHYDRAZIDE;
N' (3 PHENOXYBENZOYL) 2 (5 NITROFURAN 2 YL) 3H BENZO[D]IMIDAZOLE 5 CARBOHYDRAZIDE;
N' (3 PHENOXYBENZOYL) 2 (5 NITROTHIOPHEN 2 YL) 3H BENZO[D]IMIDAZOLE 5 CARBOHYDRAZIDE;
N' (3,4 DIMETHOXYBENZOYL) 2 (5 NITROFURAN 2 YL) 3H BENZO[D]IMIDAZOLE 5 CARBOHYDRAZIDE;
N' (3,4 DIMETHOXYBENZOYL) 2 (5 NITROTHIOPHEN 2 YL) 3H BENZO[D]IMIDAZOLE 5 CARBOHYDRAZIDE;
N' (3,4,5 TRIMETHOXYBENZOYL) 2 (5 NITROFURAN 2 YL) 3H BENZO[D]IMIDAZOLE 5 CARBOHYDRAZIDE;
N' (3,4,5 TRIMETHOXYBENZOYL) 2 (5 NITROTHIOPHEN 2 YL) 3H BENZO[D]IMIDAZOLE 5 CARBOHYDRAZIDE;
N' (4 CHLOROBENZOYL) 2 (5 NITROFURAN 2 YL) 3H BENZO[D]IMIDAZOLE 5 CARBOHYDRAZIDE;
N' (4 CHLOROBENZOYL) 2 (5 NITROTHIOPHEN 2 YL) 3H BENZO[D]IMIDAZOLE 5 CARBOHYDRAZIDE;
N' BENZOYL 2 (5 NITROFURAN 2 YL) 3H BENZO[D]IMIDAZOLE 5 CARBOHYDRAZIDE;
N' BENZOYL 2 (5 NITROTHIOPHEN 2 YL) 3H BENZO[D]IMIDAZOLE 5 CARBOXYLIC ACID;
N' FORMYL 2 (5 NITROFURAN 2 YL) 3H BENZO[D]IMIDAZOLE 5 CARBOHYDRAZIDE;
N' FORMYL 2 (5 NITROTHIOPHEN 2 YL) 3H BENZO[D]IMIDAZOLE 5 CARBOXYLIC ACID;
PEPSTATIN;
RIFAMPICIN;
UNCLASSIFIED DRUG;
ANIMAL CELL;
ANIMAL EXPERIMENT;
ANIMAL MODEL;
ARTICLE;
CANCER CELL CULTURE;
CARBON NUCLEAR MAGNETIC RESONANCE;
CONTROLLED STUDY;
CRYSTALLIZATION;
CYTOTOXICITY;
DRUG EFFICACY;
DRUG SCREENING;
DRUG STRUCTURE;
DRUG SYNTHESIS;
EMBRYO;
GROWTH INHIBITION;
HUMAN;
HUMAN CELL;
HYDROLYSIS;
IN VITRO STUDY;
INFRARED RADIATION;
MALARIA;
MALE;
MOUSE;
MULTIDRUG RESISTANT TUBERCULOSIS;
NEOPLASM;
NONHUMAN;
PARASITEMIA;
PLASMODIUM BERGHEI;
PLASMODIUM BERGHEI INFECTION;
POLYMERIZATION;
PROTEIN DEGRADATION;
PROTON NUCLEAR MAGNETIC RESONANCE;
STRUCTURE ACTIVITY RELATION;
TUBERCULOSIS;
ANIMALS;
ANTIMALARIALS;
ANTITUBERCULAR AGENTS;
BENZIMIDAZOLES;
CELL LINE, TUMOR;
DRUG RESISTANCE, MULTIPLE;
HEMIN;
HEMOGLOBINS;
HUMANS;
HYDRAZINES;
HYDROLYSIS;
MICE;
PLASMODIUM;
MURINAE;
PLASMODIUM BERGHEI;
RODENTIA;
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EID: 79952453594
PISSN: 09680896
EISSN: None
Source Type: Journal
DOI: 10.1016/j.bmc.2011.01.050 Document Type: Article |
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Times cited : (101)
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References (41)
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