-
1
-
-
0036132551
-
Roads to polyploidy: The megakaryocyte example
-
Ravid K, Lu J, Zimmet JM, Jones MR. Roads to polyploidy: the megakaryocyte example. J Cell Physiol. 2002;190(1):7-20.
-
(2002)
J Cell Physiol
, vol.190
, Issue.1
, pp. 7-20
-
-
Ravid, K.1
Lu, J.2
Zimmet, J.M.3
Jones, M.R.4
-
2
-
-
77953903257
-
Megakaryopoiesis
-
Geddis AE. Megakaryopoiesis. Semin Hematol. 2010;47(3):212-219.
-
(2010)
Semin Hematol
, vol.47
, Issue.3
, pp. 212-219
-
-
Geddis, A.E.1
-
3
-
-
0027491334
-
Acute megakaryocytic leukemia with the t(1;22)(p13;q13)
-
Lion T, Haas OA. Acute megakaryocytic leukemia with the t(1;22)(p13;q13). Leuk Lymphoma. 1993;11(1):15-20.
-
(1993)
Leuk Lymphoma
, vol.11
, Issue.1
, pp. 15-20
-
-
Lion, T.1
Haas, O.A.2
-
5
-
-
12344325677
-
GATA1 in normal and malignant hematopoiesis
-
Crispino JD. GATA1 in normal and malignant hematopoiesis. Semin Cell Dev Biol. 2005;16(1):137-147.
-
(2005)
Semin Cell Dev Biol
, vol.16
, Issue.1
, pp. 137-147
-
-
Crispino, J.D.1
-
6
-
-
0036727413
-
Acquired mutations in GATA1 in the megakaryoblastic leukemia of Down syndrome
-
Wechsler J, Greene M, McDevitt MA, et al. Acquired mutations in GATA1 in the megakaryoblastic leukemia of Down syndrome. Nat Genet. 2002;32(1):148-152.
-
(2002)
Nat Genet
, vol.32
, Issue.1
, pp. 148-152
-
-
Wechsler, J.1
Greene, M.2
McDevitt, M.A.3
-
7
-
-
63149148538
-
Insights into the manifestations, outcomes, and mechanisms of leukemogenesis in Down syndrome
-
Malinge S, Izraeli S, Crispino JD. Insights into the manifestations, outcomes, and mechanisms of leukemogenesis in Down syndrome. Blood. 2009;113(12):2619-2628.
-
(2009)
Blood
, vol.113
, Issue.12
, pp. 2619-2628
-
-
Malinge, S.1
Izraeli, S.2
Crispino, J.D.3
-
8
-
-
0033780541
-
The management of neoplastic disorders of haematopoiesis in children with Down's syndrome
-
Lange B. The management of neoplastic disorders of haematopoiesis in children with Down's syndrome. Br J Haematol. 2000;110(3):512-524.
-
(2000)
Br J Haematol
, vol.110
, Issue.3
, pp. 512-524
-
-
Lange, B.1
-
9
-
-
1842422317
-
The GATA1 mutation in an adult patient with acute megakaryoblastic leukemia not accompanying Down syndrome
-
Harigae H, Xu G, Sugawara T, Ishikawa I, Toki T, Ito E. The GATA1 mutation in an adult patient with acute megakaryoblastic leukemia not accompanying Down syndrome. Blood. 2004;103(8):3242-3243.
-
(2004)
Blood
, vol.103
, Issue.8
, pp. 3242-3243
-
-
Harigae, H.1
Xu, G.2
Sugawara, T.3
Ishikawa, I.4
Toki, T.5
Ito, E.6
-
10
-
-
0034307375
-
Acute megakaryocytic leukemia: The Eastern Cooperative Oncology Group experience
-
Tallman MS, Neuberg D, Bennett JM, et al. Acute megakaryocytic leukemia: the Eastern Cooperative Oncology Group experience. Blood. 2000;96(7):2405-2411.
-
(2000)
Blood
, vol.96
, Issue.7
, pp. 2405-2411
-
-
Tallman, M.S.1
Neuberg, D.2
Bennett, J.M.3
-
11
-
-
33745713168
-
Activating alleles of JAK3 in acute megakaryoblastic leukemia
-
Walters DK, Mercher T, Gu TL, et al. Activating alleles of JAK3 in acute megakaryoblastic leukemia. Cancer Cell. 2006;10(1):65-75.
-
(2006)
Cancer Cell
, vol.10
, Issue.1
, pp. 65-75
-
-
Walters, D.K.1
Mercher, T.2
Gu, T.L.3
-
12
-
-
1542316951
-
Fatal familial infantile myelofibrosis
-
Sheikha A. Fatal familial infantile myelofibrosis. J Pediatr Hematol Oncol. 2004;26(3):164-168.
-
(2004)
J Pediatr Hematol Oncol
, vol.26
, Issue.3
, pp. 164-168
-
-
Sheikha, A.1
-
13
-
-
0001639195
-
Some speculations on the myeloproliferative syndromes
-
Dameshek W. Some speculations on the myeloproliferative syndromes. Blood. 1951;6(4):372-375.
-
(1951)
Blood
, vol.6
, Issue.4
, pp. 372-375
-
-
Dameshek, W.1
-
14
-
-
77950918284
-
Classification and diagnosis of myeloproliferative neoplasms according to the 2008 World Health Organization criteria
-
Wadleigh M, Tefferi A. Classification and diagnosis of myeloproliferative neoplasms according to the 2008 World Health Organization criteria. Int J Hematol. 2010;91(2):174-179.
-
(2010)
Int J Hematol
, vol.91
, Issue.2
, pp. 174-179
-
-
Wadleigh, M.1
Tefferi, A.2
-
15
-
-
47649123488
-
Clinical correlates of JAK2V617F presence or allele burden in myeloproliferative neoplasms: A critical reappraisal
-
Vannucchi AM, Antonioli E, Guglielmelli P, Pardanani A, Tefferi A. Clinical correlates of JAK2V617F presence or allele burden in myeloproliferative neoplasms: a critical reappraisal. Leukemia. 2008;22(7):1299-1307.
-
(2008)
Leukemia
, vol.22
, Issue.7
, pp. 1299-1307
-
-
Vannucchi, A.M.1
Antonioli, E.2
Guglielmelli, P.3
Pardanani, A.4
Tefferi, A.5
-
16
-
-
38949160429
-
Somatic mutations of JAK2 exon 12 in patients with JAK2 (V617F)-negative myeloproliferative disorders
-
Pietra D, Li S, Brisci A, et al. Somatic mutations of JAK2 exon 12 in patients with JAK2 (V617F)-negative myeloproliferative disorders. Blood. 2008;111(3):1686-1689.
-
(2008)
Blood
, vol.111
, Issue.3
, pp. 1686-1689
-
-
Pietra, D.1
Li, S.2
Brisci, A.3
-
17
-
-
47249092413
-
MPL mutations in myeloproliferative disorders: Analysis of the PT-1 cohort
-
Beer PA, Campbell PJ, Scott LM, et al. MPL mutations in myeloproliferative disorders: analysis of the PT-1 cohort. Blood. 2008;112(1):141-149.
-
(2008)
Blood
, vol.112
, Issue.1
, pp. 141-149
-
-
Beer, P.A.1
Campbell, P.J.2
Scott, L.M.3
-
18
-
-
77955507360
-
AML1 is overexpressed in patients with myeloproliferative neoplasms and mediates JAK2V617F-independent overexpression of NF-E2
-
Wang W, Schwemmers S, Hexner EO, Pahl HL. AML1 is overexpressed in patients with myeloproliferative neoplasms and mediates JAK2V617F-independent overexpression of NF-E2. Blood. 2010;116(2):254-266.
-
(2010)
Blood
, vol.116
, Issue.2
, pp. 254-266
-
-
Wang, W.1
Schwemmers, S.2
Hexner, E.O.3
Pahl, H.L.4
-
19
-
-
33750627651
-
JAK2T875N is a novel activating mutation that results in myeloproliferative disease with features of megakaryoblastic leukemia in a murine bone marrow transplantation model
-
Mercher T, Wernig G, Moore SA, et al. JAK2T875N is a novel activating mutation that results in myeloproliferative disease with features of megakaryoblastic leukemia in a murine bone marrow transplantation model. Blood. 2006;108(8):2770-2779.
-
(2006)
Blood
, vol.108
, Issue.8
, pp. 2770-2779
-
-
Mercher, T.1
Wernig, G.2
Moore, S.A.3
-
20
-
-
81055131632
-
Methylation of miR-34a, miR-34b/c, miR-124-1 and miR-203 in Ph-negative myeloproliferative neoplasms
-
Chim CS, Wan TS, Wong KY, Fung TK, Drexler HG, Wong KF. Methylation of miR-34a, miR-34b/c, miR-124-1 and miR-203 in Ph-negative myeloproliferative neoplasms. J Transl Med. 2011;9(1):197.
-
(2011)
J Transl Med
, vol.9
, Issue.1
, pp. 197
-
-
Chim, C.S.1
Wan, T.S.2
Wong, K.Y.3
Fung, T.K.4
Drexler, H.G.5
Wong, K.F.6
-
21
-
-
80051931772
-
New mutations and pathogenesis of myeloproliferative neoplasms
-
Vainchenker W, Delhommeau F, Constantinescu SN, Bernard OA. New mutations and pathogenesis of myeloproliferative neoplasms. Blood. 2011;118(7):1723-1735.
-
(2011)
Blood
, vol.118
, Issue.7
, pp. 1723-1735
-
-
Vainchenker, W.1
Delhommeau, F.2
Constantinescu, S.N.3
Bernard, O.A.4
-
22
-
-
39149105615
-
Proposed criteria for the diagnosis of post-polycythemia vera and post-essential thrombocythemia myelofibrosis: A consensus statement from the International Working Group for Myelofibrosis Research and Treatment
-
Barosi G, Mesa RA, Thiele J, et al. Proposed criteria for the diagnosis of post-polycythemia vera and post-essential thrombocythemia myelofibrosis: a consensus statement from the International Working Group for Myelofibrosis Research and Treatment. Leukemia. 2008;22(2):437-438.
-
(2008)
Leukemia
, vol.22
, Issue.2
, pp. 437-438
-
-
Barosi, G.1
Mesa, R.A.2
Thiele, J.3
-
23
-
-
8344229870
-
Life expectancy and prognostic factors for survival in patients with polycythemia vera and essential thrombocythemia
-
Passamonti F, Rumi E, Pungolino E, et al. Life expectancy and prognostic factors for survival in patients with polycythemia vera and essential thrombocythemia. Am J Med. 2004;117(10):755-761.
-
(2004)
Am J Med
, vol.117
, Issue.10
, pp. 755-761
-
-
Passamonti, F.1
Rumi, E.2
Pungolino, E.3
-
24
-
-
30844463437
-
Presence of unfavorable cytogenetic abnormalities is the strongest predictor of poor survival in secondary myelofibrosis
-
Dingli D, Schwager SM, Mesa RA, Li CY, Dewald GW, Tefferi A. Presence of unfavorable cytogenetic abnormalities is the strongest predictor of poor survival in secondary myelofibrosis. Cancer. 2006;106(9):1985-1989.
-
(2006)
Cancer
, vol.106
, Issue.9
, pp. 1985-1989
-
-
Dingli, D.1
Schwager, S.M.2
Mesa, R.A.3
Li, C.Y.4
Dewald, G.W.5
Tefferi, A.6
-
25
-
-
43549125836
-
A dynamic prognostic model to predict survival in post-polycythemia vera myelofibrosis
-
Passamonti F, Rumi E, Caramella M, et al. A dynamic prognostic model to predict survival in post-polycythemia vera myelofibrosis. Blood. 2008;111(7):3383-3387.
-
(2008)
Blood
, vol.111
, Issue.7
, pp. 3383-3387
-
-
Passamonti, F.1
Rumi, E.2
Caramella, M.3
-
26
-
-
67649933816
-
Reticulin accumulation in essential thrombocythemia: Prognostic significance and relationship to therapy
-
Campbell PJ, Bareford D, Erber WN, et al. Reticulin accumulation in essential thrombocythemia: prognostic significance and relationship to therapy. J Clin Oncol. 2009;27(18):2991-2999.
-
(2009)
J Clin Oncol
, vol.27
, Issue.18
, pp. 2991-2999
-
-
Campbell, P.J.1
Bareford, D.2
Erber, W.N.3
-
27
-
-
78651456842
-
The impact of peripheral blood values and bone marrow findings on prognosis for patients with essential thrombocythemia and polycythemia vera
-
Abdulkarim K, Ridell B, Johansson P, Kutti J, Safai-Kutti S, Andreasson B. The impact of peripheral blood values and bone marrow findings on prognosis for patients with essential thrombocythemia and polycythemia vera. Eur J Haematol. 2011;86(2):148-155.
-
(2011)
Eur J Haematol
, vol.86
, Issue.2
, pp. 148-155
-
-
Abdulkarim, K.1
Ridell, B.2
Johansson, P.3
Kutti, J.4
Safai-Kutti, S.5
Andreasson, B.6
-
29
-
-
25844476814
-
Idiopathic myelofibrosis
-
Barosi G, Hoffman R. Idiopathic myelofibrosis. Semin Hematol. 2005;42(4):248-258.
-
(2005)
Semin Hematol
, vol.42
, Issue.4
, pp. 248-258
-
-
Barosi, G.1
Hoffman, R.2
-
31
-
-
41349102332
-
Prognostic implications of the European consensus for grading of bone marrow fibrosis in chronic idiopathic myelofibrosis
-
Vener C, Fracchiolla NS, Gianelli U, et al. Prognostic implications of the European consensus for grading of bone marrow fibrosis in chronic idiopathic myelofibrosis. Blood. 2008;111(4):1862-1865.
-
(2008)
Blood
, vol.111
, Issue.4
, pp. 1862-1865
-
-
Vener, C.1
Fracchiolla, N.S.2
Gianelli, U.3
-
33
-
-
34848876335
-
Bone marrow fibrosis: Pathophysiology and clinical significance of increased bone marrow stromal fibres
-
Kuter DJ, Bain B, Mufti G, Bagg A, Hasserjian RP. Bone marrow fibrosis: pathophysiology and clinical significance of increased bone marrow stromal fibres. Br J Haematol. 2007;139(3):351-362.
-
(2007)
Br J Haematol
, vol.139
, Issue.3
, pp. 351-362
-
-
Kuter, D.J.1
Bain, B.2
Mufti, G.3
Bagg, A.4
Hasserjian, R.P.5
-
34
-
-
0015090542
-
Quantitation of bone marrow reticulin: A normal range
-
Bauermeister DE. Quantitation of bone marrow reticulin: a normal range. Am J Clin Pathol. 1971;56(1):24-31.
-
(1971)
Am J Clin Pathol
, vol.56
, Issue.1
, pp. 24-31
-
-
Bauermeister, D.E.1
-
35
-
-
0025605489
-
Normal reticulin level in iliac bone marrow
-
Beckman EN, Brown AW Jr. Normal reticulin level in iliac bone marrow. Arch Pathol Lab Med. 1990;114(12):1241-1243.
-
(1990)
Arch Pathol Lab Med
, vol.114
, Issue.12
, pp. 1241-1243
-
-
Beckman, E.N.1
Brown Jr., A.W.2
-
36
-
-
0025232370
-
The production of transforming growth factor-beta in acute megakaryoblastic leukemia and its possible implications in myelofibrosis
-
Terui T, Niitsu Y, Mahara K, et al. The production of transforming growth factor-beta in acute megakaryoblastic leukemia and its possible implications in myelofibrosis. Blood. 1990;75(7):1540-1548.
-
(1990)
Blood
, vol.75
, Issue.7
, pp. 1540-1548
-
-
Terui, T.1
Niitsu, Y.2
Mahara, K.3
-
37
-
-
0027525858
-
Characterization of an acute micromegakaryocytic leukaemia: Evidence for the pathogenesis of myelofibrosis
-
Reilly JT, Barnett D, Dolan G, Forrest P, Eastham J, Smith A. Characterization of an acute micromegakaryocytic leukaemia: evidence for the pathogenesis of myelofibrosis. Br J Haematol. 1993;83(1):58-62.
-
(1993)
Br J Haematol
, vol.83
, Issue.1
, pp. 58-62
-
-
Reilly, J.T.1
Barnett, D.2
Dolan, G.3
Forrest, P.4
Eastham, J.5
Smith, A.6
-
38
-
-
20944437340
-
A pathobiologic pathway linking thrombopoietin, GATA-1, and TGF-beta1 in the development of myelofibrosis
-
Vannucchi AM, Bianchi L, Paoletti F, et al. A pathobiologic pathway linking thrombopoietin, GATA-1, and TGF-beta1 in the development of myelofibrosis. Blood. 2005;105(9):3493-3501.
-
(2005)
Blood
, vol.105
, Issue.9
, pp. 3493-3501
-
-
Vannucchi, A.M.1
Bianchi, L.2
Paoletti, F.3
-
39
-
-
9244264090
-
Increased and pathologic emperipolesis of neutrophils within megakaryocytes associated with marrow fibrosis in GATA-1(low) mice
-
Centurione L, Di Baldassarre A, Zingariello M, et al. Increased and pathologic emperipolesis of neutrophils within megakaryocytes associated with marrow fibrosis in GATA-1(low) mice. Blood. 2004;104(12):3573-3580.
-
(2004)
Blood
, vol.104
, Issue.12
, pp. 3573-3580
-
-
Centurione, L.1
Di Baldassarre, A.2
Zingariello, M.3
-
40
-
-
84868000107
-
The relationship of the active and latent forms of TGF-beta1 with marrow fibrosis in essential thrombocythemia and primary myelofibrosis
-
published online ahead of print December 27, doi:10.1007/s12032-011-0144- 1
-
Ponce CC, de Lourdes FCM, Ihara SS, Silva MR. The relationship of the active and latent forms of TGF-beta1 with marrow fibrosis in essential thrombocythemia and primary myelofibrosis [published online ahead of print December 27, 2011]. Med Oncol. doi:10.1007/s12032-011-0144-1.
-
(2011)
Med Oncol
-
-
Ponce, C.C.1
De Lourdes, F.C.M.2
Ihara, S.S.3
Silva, M.R.4
-
41
-
-
77952906589
-
Pathological interactions between hematopoietic stem cells and their niche revealed by mouse models of primary myelofibrosis
-
Varricchio L, Mancini A, Migliaccio AR. Pathological interactions between hematopoietic stem cells and their niche revealed by mouse models of primary myelofibrosis. Expert Rev Hematol. 2009; 2(3):315-334.
-
(2009)
Expert Rev Hematol
, vol.2
, Issue.3
, pp. 315-334
-
-
Varricchio, L.1
Mancini, A.2
Migliaccio, A.R.3
-
42
-
-
0023066669
-
Abnormal splenic megakaryopoiesis in MPSV-induced myeloproliferative disease
-
Le Bousse-Kerdiles MC, Fernandez-Delgado R, Smadja-Joffe F, et al. Abnormal splenic megakaryopoiesis in MPSV-induced myeloproliferative disease. Leuk Res. 1987;11(9):781-787.
-
(1987)
Leuk Res
, vol.11
, Issue.9
, pp. 781-787
-
-
Le Bousse-Kerdiles, M.C.1
Fernandez-Delgado, R.2
Smadja-Joffe, F.3
-
43
-
-
0031020240
-
Transgenic mice overexpressing human c-mpl ligand exhibit chronic thrombocytosis and display enhanced recovery from 5-fluorouracil or antiplatelet serum treatment
-
Zhou W, Toombs CF, Zou T, Guo J, Robinson MO. Transgenic mice overexpressing human c-mpl ligand exhibit chronic thrombocytosis and display enhanced recovery from 5-fluorouracil or antiplatelet serum treatment. Blood. 1997;89(5):1551-1559.
-
(1997)
Blood
, vol.89
, Issue.5
, pp. 1551-1559
-
-
Zhou, W.1
Toombs, C.F.2
Zou, T.3
Guo, J.4
Robinson, M.O.5
-
44
-
-
20344393115
-
Transgenic mice overexpressing murine thrombopoietin develop myelofibrosis and osteosclerosis
-
Kakumitsu H, Kamezaki K, Shimoda K, et al. Transgenic mice overexpressing murine thrombopoietin develop myelofibrosis and osteosclerosis. Leuk Res. 2005;29(7):761-769.
-
(2005)
Leuk Res
, vol.29
, Issue.7
, pp. 761-769
-
-
Kakumitsu, H.1
Kamezaki, K.2
Shimoda, K.3
-
45
-
-
70449704426
-
Evaluation of bone marrow reticulin formation in chronic immune thrombocytopenia patients treated with romiplostim
-
Kuter DJ, Mufti GJ, Bain BJ, Hasserjian RP, Davis W, Rutstein M. Evaluation of bone marrow reticulin formation in chronic immune thrombocytopenia patients treated with romiplostim. Blood. 2009;114(18):3748-3756.
-
(2009)
Blood
, vol.114
, Issue.18
, pp. 3748-3756
-
-
Kuter, D.J.1
Mufti, G.J.2
Bain, B.J.3
Hasserjian, R.P.4
Davis, W.5
Rutstein, M.6
-
46
-
-
0031963996
-
Adenovector-mediated expression of human thrombopoietin cDNA in immune-compromised mice: Insights into the pathophysiology of osteomyelofibrosis
-
Frey BM, Rafii S, Teterson M, Eaton D, Crystal RG, Moore MA. Adenovector-mediated expression of human thrombopoietin cDNA in immune-compromised mice: insights into the pathophysiology of osteomyelofibrosis. J Immunol. 1998;160(2):691-699.
-
(1998)
J Immunol
, vol.160
, Issue.2
, pp. 691-699
-
-
Frey, B.M.1
Rafii, S.2
Teterson, M.3
Eaton, D.4
Crystal, R.G.5
Moore, M.A.6
-
47
-
-
77953274727
-
Physiological Jak2V617F expression causes a lethal myeloproliferative neoplasm with differential effects on hematopoietic stem and progenitor cells
-
Mullally A, Lane SW, Ball B, et al. Physiological Jak2V617F expression causes a lethal myeloproliferative neoplasm with differential effects on hematopoietic stem and progenitor cells. Cancer Cell. 2010;17(6):584-596.
-
(2010)
Cancer Cell
, vol.17
, Issue.6
, pp. 584-596
-
-
Mullally, A.1
Lane, S.W.2
Ball, B.3
-
48
-
-
77951759127
-
Conditional expression of heterozygous or homozygous Jak2V617F from its endogenous promoter induces a polycythemia vera-like disease
-
Akada H, Yan D, Zou H, Fiering S, Hutchison RE, Mohi MG. Conditional expression of heterozygous or homozygous Jak2V617F from its endogenous promoter induces a polycythemia vera-like disease. Blood. 2010;115(17):3589-3597.
-
(2010)
Blood
, vol.115
, Issue.17
, pp. 3589-3597
-
-
Akada, H.1
Yan, D.2
Zou, H.3
Fiering, S.4
Hutchison, R.E.5
Mohi, M.G.6
-
49
-
-
43249084493
-
Ratio of mutant JAK2-V617F to wild-type Jak2 determines the MPD phenotypes in transgenic mice
-
Tiedt R, Hao-Shen H, Sobas MA, et al. Ratio of mutant JAK2-V617F to wild-type Jak2 determines the MPD phenotypes in transgenic mice. Blood. 2008;111(8):3931-3940.
-
(2008)
Blood
, vol.111
, Issue.8
, pp. 3931-3940
-
-
Tiedt, R.1
Hao-Shen, H.2
Sobas, M.A.3
-
50
-
-
33744490974
-
Expression of Jak2V617F causes a polycythemia vera-like disease with associated myelofibrosis in a murine bone marrow transplant model
-
Wernig G, Mercher T, Okabe R, Levine RL, Lee BH, Gilliland DG. Expression of Jak2V617F causes a polycythemia vera-like disease with associated myelofibrosis in a murine bone marrow transplant model. Blood. 2006;107(11):4274-4281.
-
(2006)
Blood
, vol.107
, Issue.11
, pp. 4274-4281
-
-
Wernig, G.1
Mercher, T.2
Okabe, R.3
Levine, R.L.4
Lee, B.H.5
Gilliland, D.G.6
-
51
-
-
33745721197
-
JAK2V617F expression in murine hematopoietic cells leads to MPD mimicking human PV with secondary myelofibrosis
-
Lacout C, Pisani DF, Tulliez M, Gachelin FM, Vainchenker W, Villeval JL. JAK2V617F expression in murine hematopoietic cells leads to MPD mimicking human PV with secondary myelofibrosis. Blood. 2006;108(5):1652-1660.
-
(2006)
Blood
, vol.108
, Issue.5
, pp. 1652-1660
-
-
Lacout, C.1
Pisani, D.F.2
Tulliez, M.3
Gachelin, F.M.4
Vainchenker, W.5
Villeval, J.L.6
-
52
-
-
34248547646
-
Bone changes in myelofibrosis with myeloid metaplasia: A histomorphometric and microcomputed tomographic study
-
Schmidt A, Blanchet O, Dib M, Basle MF, Ifrah N, Chappard D. Bone changes in myelofibrosis with myeloid metaplasia: a histomorphometric and microcomputed tomographic study. Eur J Haematol. 2007;78(6):500-509.
-
(2007)
Eur J Haematol
, vol.78
, Issue.6
, pp. 500-509
-
-
Schmidt, A.1
Blanchet, O.2
Dib, M.3
Basle, M.F.4
Ifrah, N.5
Chappard, D.6
-
53
-
-
33746437130
-
MPLW515L is a novel somatic activating mutation in myelofibrosis with myeloid metaplasia
-
Pikman Y, Lee BH, Mercher T, et al. MPLW515L is a novel somatic activating mutation in myelofibrosis with myeloid metaplasia. PLoS Med. 2006;3(7):e270.
-
(2006)
PLoS Med
, vol.3
, Issue.7
-
-
Pikman, Y.1
Lee, B.H.2
Mercher, T.3
-
54
-
-
54049107944
-
Activating mutations in human acute megakaryoblastic leukemia
-
Malinge S, Ragu C, Della-Valle V, et al. Activating mutations in human acute megakaryoblastic leukemia. Blood. 2008;112(10):4220-4226.
-
(2008)
Blood
, vol.112
, Issue.10
, pp. 4220-4226
-
-
Malinge, S.1
Ragu, C.2
Della-Valle, V.3
-
55
-
-
65249094196
-
The OTTMAL fusion oncogene activates RBPJ-mediated transcription and induces acute megakaryoblastic leukemia in a knockin mouse model
-
Mercher T, Raffel GD, Moore SA, et al. The OTTMAL fusion oncogene activates RBPJ-mediated transcription and induces acute megakaryoblastic leukemia in a knockin mouse model. J Clin Invest. 2009;119(4):852-864.
-
(2009)
J Clin Invest
, vol.119
, Issue.4
, pp. 852-864
-
-
Mercher, T.1
Raffel, G.D.2
Moore, S.A.3
-
56
-
-
0035874524
-
Accentuated response to phenylhydrazine and erythropoietin in mice genetically impaired for their GATA-1 expression (GATA-1(low) mice)
-
Vannucchi AM, Bianchi L, Cellai C, et al. Accentuated response to phenylhydrazine and erythropoietin in mice genetically impaired for their GATA-1 expression (GATA-1(low) mice). Blood. 2001;97(10):3040-3050.
-
(2001)
Blood
, vol.97
, Issue.10
, pp. 3040-3050
-
-
Vannucchi, A.M.1
Bianchi, L.2
Cellai, C.3
-
57
-
-
0037103206
-
Development of myelofibrosis in mice genetically impaired for GATA-1 expression (GATA-1(low) mice)
-
Vannucchi AM, Bianchi L, Cellai C, et al. Development of myelofibrosis in mice genetically impaired for GATA-1 expression (GATA-1(low) mice). Blood. 2002;100(4):1123-1132.
-
(2002)
Blood
, vol.100
, Issue.4
, pp. 1123-1132
-
-
Vannucchi, A.M.1
Bianchi, L.2
Cellai, C.3
-
58
-
-
38349119730
-
Highly penetrant myeloproliferative disease in the Ts65Dn mouse model of Down syndrome
-
Kirsammer G, Jilani S, Liu H, et al. Highly penetrant myeloproliferative disease in the Ts65Dn mouse model of Down syndrome. Blood. 2008;111(2):767-775.
-
(2008)
Blood
, vol.111
, Issue.2
, pp. 767-775
-
-
Kirsammer, G.1
Jilani, S.2
Liu, H.3
-
59
-
-
84859255284
-
Management of myeloproliferative neoplasms: From academic guidelines to clinical practice
-
Barosi G, Lupo L, Rosti V. Management of myeloproliferative neoplasms: from academic guidelines to clinical practice. Curr Hematol Malig Rep. 2012;7(1):50-56.
-
(2012)
Curr Hematol Malig Rep
, vol.7
, Issue.1
, pp. 50-56
-
-
Barosi, G.1
Lupo, L.2
Rosti, V.3
-
60
-
-
0026639799
-
Analysis of the mechanism of anagrelide-induced thrombocytopenia in humans
-
Mazur EM, Rosmarin AG, Sohl PA, Newton JL, Narendran A. Analysis of the mechanism of anagrelide-induced thrombocytopenia in humans. Blood. 1992;79(8):1931-1937.
-
(1992)
Blood
, vol.79
, Issue.8
, pp. 1931-1937
-
-
Mazur, E.M.1
Rosmarin, A.G.2
Sohl, P.A.3
Newton, J.L.4
Narendran, A.5
-
61
-
-
80054106619
-
Janus kinase inhibitors: An update on the progress and promise of targeted therapy in the myeloproliferative neoplasms
-
Stein BL, Crispino JD, Moliterno AR. Janus kinase inhibitors: an update on the progress and promise of targeted therapy in the myeloproliferative neoplasms. Curr Opin Oncol. 2011;23(6):609-616.
-
(2011)
Curr Opin Oncol
, vol.23
, Issue.6
, pp. 609-616
-
-
Stein, B.L.1
Crispino, J.D.2
Moliterno, A.R.3
-
62
-
-
80052184481
-
Safety and efficacy of everolimus, a mTOR inhibitor, as single agent in a phase 1/2 study in patients with myelofibrosis
-
Guglielmelli P, Barosi G, Rambaldi A, et al. Safety and efficacy of everolimus, a mTOR inhibitor, as single agent in a phase 1/2 study in patients with myelofibrosis. Blood. 2011;118(8):2069-2076.
-
(2011)
Blood
, vol.118
, Issue.8
, pp. 2069-2076
-
-
Guglielmelli, P.1
Barosi, G.2
Rambaldi, A.3
-
63
-
-
77955168425
-
A pilot study of the histone-deacetylase inhibitor Givinostat in patients with JAK2V617F positive chronic myeloproliferative neoplasms
-
Rambaldi A, Dellacasa CM, Finazzi G, et al. A pilot study of the histone-deacetylase inhibitor Givinostat in patients with JAK2V617F positive chronic myeloproliferative neoplasms. Br J Haematol. 2010;150(4):446-455.
-
(2010)
Br J Haematol
, vol.150
, Issue.4
, pp. 446-455
-
-
Rambaldi, A.1
Dellacasa, C.M.2
Finazzi, G.3
-
64
-
-
77957029255
-
Phase II study of obatoclax mesylate (GX15-070), a small-molecule BCL-2 family antagonist, for patients with myelofibrosis
-
Parikh SA, Kantarjian H, Schimmer A, et al. Phase II study of obatoclax mesylate (GX15-070), a small-molecule BCL-2 family antagonist, for patients with myelofibrosis. Clin Lymphoma Myeloma Leuk. 2010;10(4):285-289.
-
(2010)
Clin Lymphoma Myeloma Leuk
, vol.10
, Issue.4
, pp. 285-289
-
-
Parikh, S.A.1
Kantarjian, H.2
Schimmer, A.3
-
65
-
-
84863393110
-
A double-blind, placebo-controlled trial of ruxolitinib for myelofibrosis
-
Verstovsek S, Mesa RA, Gotlib J, et al. A double-blind, placebo-controlled trial of ruxolitinib for myelofibrosis. N Engl J Med. 2012;366(9):799-807.
-
(2012)
N Engl J Med
, vol.366
, Issue.9
, pp. 799-807
-
-
Verstovsek, S.1
Mesa, R.A.2
Gotlib, J.3
-
66
-
-
77950684805
-
Preclinical characterization of the selective JAK1/2 inhibitor INCB018424: Therapeutic implications for the treatment of myeloproliferative neoplasms
-
Quintas-Cardama A, Vaddi K, Liu P, et al. Preclinical characterization of the selective JAK1/2 inhibitor INCB018424: therapeutic implications for the treatment of myeloproliferative neoplasms. Blood. 2005;115(15):3109-3117.
-
(2005)
Blood
, vol.115
, Issue.15
, pp. 3109-3117
-
-
Quintas-Cardama, A.1
Vaddi, K.2
Liu, P.3
-
67
-
-
84857837774
-
JAK inhibition with ruxolitinib versus best available therapy for myelofibrosis
-
Harrison C, Kiladjian JJ, Al-Ali HK, et al. JAK inhibition with ruxolitinib versus best available therapy for myelofibrosis. N Engl J Med. 2012; 366(9):787-798.
-
(2012)
N Engl J Med
, vol.366
, Issue.9
, pp. 787-798
-
-
Harrison, C.1
Kiladjian, J.J.2
Al-Ali, H.K.3
-
68
-
-
47049098437
-
Lestaurtinib (CEP701) is a JAK2 inhibitor that suppresses JAK2/STAT5 signaling and the proliferation of primary erythroid cells from patients with myeloproliferative disorders
-
Hexner EO, Serdikoff C, Jan M, et al. Lestaurtinib (CEP701) is a JAK2 inhibitor that suppresses JAK2/STAT5 signaling and the proliferation of primary erythroid cells from patients with myeloproliferative disorders. Blood. 2008;111(12):5663-5671.
-
(2008)
Blood
, vol.111
, Issue.12
, pp. 5663-5671
-
-
Hexner, E.O.1
Serdikoff, C.2
Jan, M.3
-
69
-
-
77949535491
-
Phase 2 study of CEP-701, an orally available JAK2 inhibitor, in patients with primary or post-polycythemia vera/essential thrombocythemia myelofibrosis
-
Santos FP, Kantarjian HM, Jain N, et al. Phase 2 study of CEP-701, an orally available JAK2 inhibitor, in patients with primary or post-polycythemia vera/essential thrombocythemia myelofibrosis. Blood. 2010;115(6):1131-1136.
-
(2010)
Blood
, vol.115
, Issue.6
, pp. 1131-1136
-
-
Santos, F.P.1
Kantarjian, H.M.2
Jain, N.3
-
70
-
-
33344475032
-
Immunomodulatory drugs
-
Crane E, List A. Immunomodulatory drugs. Cancer Invest. 2005;23(7):625-634.
-
(2005)
Cancer Invest
, vol.23
, Issue.7
, pp. 625-634
-
-
Crane, E.1
List, A.2
-
71
-
-
70350439432
-
Lenalidomide plus prednisone results in durable clinical, histopathologic, and molecular responses in patients with myelofibrosis
-
Quintas-Cardama A, Kantarjian HM, Manshouri T, et al. Lenalidomide plus prednisone results in durable clinical, histopathologic, and molecular responses in patients with myelofibrosis. J Clin Oncol. 2009;27(28):4760-4766.
-
(2009)
J Clin Oncol
, vol.27
, Issue.28
, pp. 4760-4766
-
-
Quintas-Cardama, A.1
Kantarjian, H.M.2
Manshouri, T.3
-
72
-
-
71949121402
-
Pomalidomide is active in the treatment of anemia associated with myelofibrosis
-
Tefferi A, Verstovsek S, Barosi G, et al. Pomalidomide is active in the treatment of anemia associated with myelofibrosis. J Clin Oncol. 2009; 27(27):4563-4569.
-
(2009)
J Clin Oncol
, vol.27
, Issue.27
, pp. 4563-4569
-
-
Tefferi, A.1
Verstovsek, S.2
Barosi, G.3
-
73
-
-
0037371153
-
Lysyl oxidase: Properties, specificity, and biological roles inside and outside of the cell
-
Kagan HM, Li W. Lysyl oxidase: properties, specificity, and biological roles inside and outside of the cell. J Cell Biochem. 2003;88(4):660-672.
-
(2003)
J Cell Biochem
, vol.88
, Issue.4
, pp. 660-672
-
-
Kagan, H.M.1
Li, W.2
-
74
-
-
42049091013
-
Bone morphogenetic proteins are overexpressed in the bone marrow of primary myelofibrosis and are apparently induced by fibrogenic cytokines
-
Bock O, Hoftmann J, Theophile K, et al. Bone morphogenetic proteins are overexpressed in the bone marrow of primary myelofibrosis and are apparently induced by fibrogenic cytokines. Am J Pathol. 2008;172(4):951-960.
-
(2008)
Am J Pathol
, vol.172
, Issue.4
, pp. 951-960
-
-
Bock, O.1
Hoftmann, J.2
Theophile, K.3
-
75
-
-
79960975821
-
Control of megakaryocyte expansion and bone marrow fibrosis by lysyl oxidase
-
Eliades A, Papadantonakis N, Bhupatiraju A, et al. Control of megakaryocyte expansion and bone marrow fibrosis by lysyl oxidase. J Biol Chem. 2011;286(31):27630-27638.
-
(2011)
J Biol Chem
, vol.286
, Issue.31
, pp. 27630-27638
-
-
Eliades, A.1
Papadantonakis, N.2
Bhupatiraju, A.3
-
76
-
-
66049119129
-
The lysyl oxidase inhibitor, beta-aminopropionitrile, diminishes the metastatic colonization potential of circulating breast cancer cells
-
Bondareva A, Downey CM, Ayres F, et al. The lysyl oxidase inhibitor, beta-aminopropionitrile, diminishes the metastatic colonization potential of circulating breast cancer cells. PLoS One. 2009;4(5):e5620.
-
(2009)
PLoS One
, vol.4
, Issue.5
-
-
Bondareva, A.1
Downey, C.M.2
Ayres, F.3
-
78
-
-
0014102285
-
Studies on beta-aminopropionitrile in patients with scleroderma
-
Keiser HR, Sjoerdsma A. Studies on beta-aminopropionitrile in patients with scleroderma. Clin Pharmacol Ther. 1967;8(4):593-602.
-
(1967)
Clin Pharmacol Ther
, vol.8
, Issue.4
, pp. 593-602
-
-
Keiser, H.R.1
Sjoerdsma, A.2
-
79
-
-
0014541235
-
Some studies on the effects of beta-aminopropionitrile in patients with injured flexor tendons
-
Peacock EE Jr, Madden JW. Some studies on the effects of beta-aminopropionitrile in patients with injured flexor tendons. Surgery. 1969;66(1):215-223.
-
(1969)
Surgery
, vol.66
, Issue.1
, pp. 215-223
-
-
Peacock Jr., E.E.1
Madden, J.W.2
-
80
-
-
0019435133
-
Pharmacologic control of surface scarring in human beings
-
Peacock EE Jr. Pharmacologic control of surface scarring in human beings. Ann Surg. 1981;193(5):592-597.
-
(1981)
Ann Surg
, vol.193
, Issue.5
, pp. 592-597
-
-
Peacock Jr., E.E.1
-
81
-
-
0018071356
-
Administration of beta-aminopropionitrile to human beings with urethral strictures: A preliminary report
-
Peacock EE, Madden JW. Administration of beta-aminopropionitrile to human beings with urethral strictures: a preliminary report. Am J Surg. 1978;136(5):600-605.
-
(1978)
Am J Surg
, vol.136
, Issue.5
, pp. 600-605
-
-
Peacock, E.E.1
Madden, J.W.2
-
82
-
-
0015738226
-
Biologic frontiers in the control of healing: Thomas G. Orr Memorial Lecture
-
Peacock EE Jr. Biologic frontiers in the control of healing: Thomas G. Orr Memorial Lecture. Am J Surg. 1973;126(6):708-713.
-
(1973)
Am J Surg
, vol.126
, Issue.6
, pp. 708-713
-
-
Peacock Jr., E.E.1
-
83
-
-
53049099771
-
Lysyl oxidase oxidizes cell membrane proteins and enhances the chemotactic response of vascular smooth muscle cells
-
Lucero HA, Ravid K, Grimsby JL, et al. Lysyl oxidase oxidizes cell membrane proteins and enhances the chemotactic response of vascular smooth muscle cells. J Biol Chem. 2008;283(35):24103-24117.
-
(2008)
J Biol Chem
, vol.283
, Issue.35
, pp. 24103-24117
-
-
Lucero, H.A.1
Ravid, K.2
Grimsby, J.L.3
-
84
-
-
0031893071
-
Lysyl oxidase: Properties, regulation and multiple functions in biology
-
Smith-Mungo LI, Kagan HM. Lysyl oxidase: properties, regulation and multiple functions in biology. Matrix Biol. 1998;16(7):387-398.
-
(1998)
Matrix Biol
, vol.16
, Issue.7
, pp. 387-398
-
-
Smith-Mungo, L.I.1
Kagan, H.M.2
-
85
-
-
34548483665
-
Cloning and characterization of the rat lysyl oxidase gene promoter: Identification of core promoter elements and functional nuclear factor I-binding sites
-
Gao S, Zhao Y, Kong L, et al. Cloning and characterization of the rat lysyl oxidase gene promoter: identification of core promoter elements and functional nuclear factor I-binding sites. J Biol Chem. 2007;282(35):25322- 25337.
-
(2007)
J Biol Chem
, vol.282
, Issue.35
, pp. 25322-25337
-
-
Gao, S.1
Zhao, Y.2
Kong, L.3
-
86
-
-
79952216170
-
The HIF-1-inducible lysyl oxidase activates HIF-1 via the Akt pathway in a positive regulation loop and synergizes with HIF-1 in promoting tumor cell growth
-
Pez F, Dayan F, Durivault J, et al. The HIF-1-inducible lysyl oxidase activates HIF-1 via the Akt pathway in a positive regulation loop and synergizes with HIF-1 in promoting tumor cell growth. Cancer Res. 2011;71(5):1647-1657.
-
(2011)
Cancer Res
, vol.71
, Issue.5
, pp. 1647-1657
-
-
Pez, F.1
Dayan, F.2
Durivault, J.3
-
87
-
-
0028866465
-
Identification of lysyl oxidase and other platelet-derived growth factor-inducible genes in vascular smooth muscle cells by differential screening
-
Green RS, Lieb ME, Weintraub AS, et al. Identification of lysyl oxidase and other platelet-derived growth factor-inducible genes in vascular smooth muscle cells by differential screening. Lab Invest. 1995;73(4):476-482.
-
(1995)
Lab Invest
, vol.73
, Issue.4
, pp. 476-482
-
-
Green, R.S.1
Lieb, M.E.2
Weintraub, A.S.3
-
88
-
-
0033397790
-
Regulation of lysyl oxidase, collagen, and connective tissue growth factor by TGF-beta1 and detection in human gingiva
-
Hong HH, Uzel MI, Duan C, Sheff MC, Trackman PC. Regulation of lysyl oxidase, collagen, and connective tissue growth factor by TGF-beta1 and detection in human gingiva. Lab Invest. 1999;79(12):1655-1667.
-
(1999)
Lab Invest
, vol.79
, Issue.12
, pp. 1655-1667
-
-
Hong, H.H.1
Uzel, M.I.2
Duan, C.3
Sheff, M.C.4
Trackman, P.C.5
-
90
-
-
34547769774
-
Paradoxical roles for lysyl oxidases in cancer: A prospect
-
Payne SL, Hendrix MJ, Kirschmann DA. Paradoxical roles for lysyl oxidases in cancer: a prospect. J Cell Biochem. 2007;101(6):1338-1354.
-
(2007)
J Cell Biochem
, vol.101
, Issue.6
, pp. 1338-1354
-
-
Payne, S.L.1
Hendrix, M.J.2
Kirschmann, D.A.3
-
91
-
-
67149096234
-
Lysyl oxidases in mammalian development and certain pathological conditions
-
Maki JM. Lysyl oxidases in mammalian development and certain pathological conditions. Histol Histopathol. 2009;24(5):651-660.
-
(2009)
Histol Histopathol
, vol.24
, Issue.5
, pp. 651-660
-
-
Maki, J.M.1
-
92
-
-
77956425361
-
Allosteric inhibition of lysyl oxidase-like-2 impedes the development of a pathologic microenvironment
-
Barry-Hamilton V, Spangler R, Marshall D, et al. Allosteric inhibition of lysyl oxidase-like-2 impedes the development of a pathologic microenvironment. Nat Med. 2010;16(9):1009-1017.
-
(2010)
Nat Med
, vol.16
, Issue.9
, pp. 1009-1017
-
-
Barry-Hamilton, V.1
Spangler, R.2
Marshall, D.3
-
93
-
-
34147179036
-
Interrelation between polyploidization and megakaryocyte differentiation: A gene profiling approach
-
Raslova H, Kauffmann A, Sekkai D, et al. Interrelation between polyploidization and megakaryocyte differentiation: a gene profiling approach. Blood. 2007;109(8):3225-3234.
-
(2007)
Blood
, vol.109
, Issue.8
, pp. 3225-3234
-
-
Raslova, H.1
Kauffmann, A.2
Sekkai, D.3
-
94
-
-
60649102218
-
Proteomics of the TRAP-induced platelet releasate
-
Piersma SR, Broxterman HJ, Kapci M, et al. Proteomics of the TRAP-induced platelet releasate. J Proteomics. 2009;72(1):91-109.
-
(2009)
J Proteomics
, vol.72
, Issue.1
, pp. 91-109
-
-
Piersma, S.R.1
Broxterman, H.J.2
Kapci, M.3
-
95
-
-
69249217790
-
Lysyl oxidase (lox) gene deficiency affects osteoblastic phenotype
-
Pischon N, Maki JM, Weisshaupt P, et al. Lysyl oxidase (lox) gene deficiency affects osteoblastic phenotype. Calcif Tissue Int. 2009;85(2):119-126.
-
(2009)
Calcif Tissue Int
, vol.85
, Issue.2
, pp. 119-126
-
-
Pischon, N.1
Maki, J.M.2
Weisshaupt, P.3
-
96
-
-
80053648630
-
Lysyl oxidase-like protein-2 regulates sprouting angiogenesis and type IV collagen assembly in the endothelial basement membrane
-
Bignon M, Pichol-Thievend C, Hardouin J, et al. Lysyl oxidase-like protein-2 regulates sprouting angiogenesis and type IV collagen assembly in the endothelial basement membrane. Blood. 2011;118(14):3979-3989.
-
(2011)
Blood
, vol.118
, Issue.14
, pp. 3979-3989
-
-
Bignon, M.1
Pichol-Thievend, C.2
Hardouin, J.3
-
97
-
-
0030718597
-
High thrombopoietin production by hematopoietic cells induces a fatal myeloproliferative syndrome in mice
-
Villeval JL, Cohen-Solal K, Tulliez M, et al. High thrombopoietin production by hematopoietic cells induces a fatal myeloproliferative syndrome in mice. Blood. 1997;90(11):4369-4383.
-
(1997)
Blood
, vol.90
, Issue.11
, pp. 4369-4383
-
-
Villeval, J.L.1
Cohen-Solal, K.2
Tulliez, M.3
-
98
-
-
34347384179
-
A novel fusion of RBM6 to CSF1R in acute megakaryoblastic leukemia
-
Gu TL, Mercher T, Tyner JW, et al. A novel fusion of RBM6 to CSF1R in acute megakaryoblastic leukemia. Blood. 2007;110(1):323-333.
-
(2007)
Blood
, vol.110
, Issue.1
, pp. 323-333
-
-
Gu, T.L.1
Mercher, T.2
Tyner, J.W.3
-
99
-
-
20144387545
-
Transgenic expression of BACH1 transcription factor results in megakaryocytic impairment
-
Toki T, Katsuoka F, Kanezaki R, et al. Transgenic expression of BACH1 transcription factor results in megakaryocytic impairment. Blood. 2005;105(8):3100-3108.
-
(2005)
Blood
, vol.105
, Issue.8
, pp. 3100-3108
-
-
Toki, T.1
Katsuoka, F.2
Kanezaki, R.3
-
100
-
-
84856911269
-
A novel murine model of myeloproliferative disorders generated by overexpression of the transcription factor NF-E2
-
Kaufmann KB, Grunder A, Hadlich T, et al. A novel murine model of myeloproliferative disorders generated by overexpression of the transcription factor NF-E2. J Exp Med. 2012;209(1):35-50.
-
(2012)
J Exp Med
, vol.209
, Issue.1
, pp. 35-50
-
-
Kaufmann, K.B.1
Grunder, A.2
Hadlich, T.3
|