Proteomics of the TRAP-induced platelet releasate

Journal of Proteomics

Volumn 72, Issue 1, 2009, Pages 91-109

  Piersma, Sander R ^a   Broxterman, Henk J ^a   Kapci, Muhammed ^a   de Haas, Richard R ^a   Hoekman, Klaas ^a   Verheul, Henk M W ^a   Jiménez, Connie R ^a  

^a VU UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Platelets; Proteomics; Releasate; TRAP

Indexed keywords

PROTEOME; SIGNAL PEPTIDE; THROMBIN RECEPTOR ACTIVATING PEPTIDE;

ARTICLE; DATA MINING; GEL ELECTROPHORESIS; HUMAN; MASS SPECTROMETRY; MICROPARTICLE ENZYME IMMUNOASSAY; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN SECRETION; PROTEOMICS; THROMBOCYTE; THROMBOCYTE RELEASE REACTION;

BLOOD PLATELETS; EXOCYTOSIS; HUMANS; PROTEOME; RECEPTORS, THROMBIN; SECRETORY VESICLES; TANDEM MASS SPECTROMETRY;

EID: 60649102218     PISSN: 18743919     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jprot.2008.10.009     Document Type: Article

References (35)

1. Wagner D.D., and Burger P.C. Platelets in inflammation and thrombosis. Arterioscler Thromb Vasc Biol 23 (2003) 2131-2137
2. Pipili-Synetos E., Papadimitriou E., and Maragoudakis M.E. Evidence that platelets promote tube formation by endothelial cells on matrigel. Br J Pharmacol 125 (1998) 1252-1257
3. Verheul H.M., Hoekman K., Lupu F., Broxterman H.J., van der Valk P., Kakkar A.K., et al. Platelet and coagulation activation with vascular endothelial growth factor generation in soft tissue sarcomas. Clin Cancer Res 6 (2000) 166-171
4. Rhee J.S., Black M., Schubert U., Fischer S., Morgenstern E., Hammes H.P., et al. The functional role of blood platelet components in angiogenesis. Thromb Haemost 92 (2004) 394-402
5. Folkman J., Browder T., and Palmblad J. Angiogenesis research: guidelines for translation to clinical application. Thromb Haemost 86 (2001) 23-33
6. King S.M., and Reed G.L. Development of platelet secretory granules. Semin Cell Dev Biol 13 (2002) 293-302
7. Verheul H.M., Hoekman K., Luykx-de Bakker S., Eekman C.A., Folman C.C., Broxterman H.J., et al. Platelet: transporter of vascular endothelial growth factor. Clin Cancer Res 3 (1997) 2187-2190
8. Ma L., Hollenberg M.D., and Wallace J.L. Thrombin-induced platelet endostatin release is blocked by a proteinase activated receptor-4 (PAR4) antagonist. Br J Pharmacol 134 (2001) 701-704
9. Kopp H.G., Hooper A.T., Broekman J., Avecilla S.T., Petit I., Luo M., et al. Thrombospondins deployed by thrombopoetic cells determine angiogenic switch and extent of revascularization. J Clin Invest 116 (2006) 3277-3291
10. Italiano Jr. J.E., Richardson J.L., Patel-Hett S., Battinelli E., Zaslavsky A., Short S., et al. Angiogenesis is regulated by a novel mechanism: pro- and anti-angiogenic proteins are organized into separate platelet α-granules and differentially released. Blood 111 (2008) 1227-1233
11. Jiménez C.R., Piersma S., and Pham T.V. High-throughput and targeted in-depth mass spectrometry-based approaches for biofluid profiling and biomarker discovery. Biomarkers Med 4 (2007) 541-565
12. Coppinger J.A., Cagney G., Toomey S., Kislinger T., Belton O., McRedmond J.P., et al. Characterization of the proteins released from activated platelets leads to localization of novel platelet proteins in human atherosclerotic lesions. Blood 103 (2004) 2096-2104
13. Shevchenko A., Wilm M., Vorm O., and Mann M. Mass spectrometric sequencing of proteins silver-stained polyacrylamide gels. Anal Chem 68 (1996) 850-858
14. Keller A., Nesvizhskii A.I., Kolker E., and Aebersold R. Empirical statistical model to estimate the accuracy of peptide identifications made by MS/MS and database search. Anal Chem 74 (2002) 5383-5392
15. Nesvizhskii A.I., Keller A., Kolker E., and Aebersold R. A statistical model for identifying proteins by tandem mass spectrometry. Anal Chem 75 (2003) 4646-4658
16. Coppinger J.A., O'Connor R., Wynne K., Flanagan M., Sullivan M., Maguire P.B., et al. Moderation of the platelet releasate response by aspirin. Blood 109 (2007) 4786-4792
17. Garcia B.A., Smalley D.M., Cho H., Shabanaowitz J., Ley K., and Hunt D.F. The platelet microparticle proteome. J Proteome Res 4 (2005) 1516-1521
18. Maynard D.M., Heijnen H.F., Horne M.K., White J.G., and Gahl W.A. Proteomic analysis of platelet a-granules using mass spectrometry. J Thromb Haemost 5 (2007) 1945-1955
19. Van Hensbergen Y., Broxterman H.J., Hanemaaijer R., Jorna A.S., van Lent N.A., Verheul H.M., et al. Soluble aminopeptidase N/CD13 in malignant and nonmalignant effusions and intratumoral fluid. Clin Cancer Res 8 (2002) 3747-3754
20. Zhang H., Liu A.Y., Loriaux P., Wollscheid B., Zhou Y., Watts J.D., et al. Mass spectrometric detection of tissue proteins in plasma. Mol Cell Prot 6 (2007) 64-71
21. Petricoin E.F., Belluco C., Araujo R.P., and Liotta L.A. The blood peptidome: a higher dimension of information content for cancer biomarker discovery. Nat Rev Cancer 6 (2006) 961-967
22. Cervi D., Yip T.T., Bhattacharya N., Podust V.N., Peterson J., Abou-Slaybi A., et al. Platelet-associated PF-4 as a biomarker of early tumor growth. Blood 111 (2008) 1201-1207
23. Petrich B.G., Marchese P., Ruggeri Z.M., Spiess S., Weichert R.A.M., Ye F., et al. Talin is required for integrin-mediated platelet function in hemostasis and thrombosis. J Exp Med 204 (2007) 3103-3111
24. Nieswandt B., Moser M., Pleines I., Varga-Szabo D., Monkley S., Critchley D., et al. Loss of talin1 in platelets abrogates integrin activation, platelet aggregation, and thrombus formation in vitro and in vivo. J Exp Med 204 (2007) 3113-3118
25. Reed G.L. Platelet secretory mechanisms. Semin Thromb Hemost 30 (2004) 441-450
26. Manickam N., Sun X., Li M., Gazitt Y., and Essex D.W. Protein disulphide isomerise in platelet function. Br J Haematol 140 (2008) 223-229
27. Cho J., Furie B.C., Coughlin S.R., and Furie B. A critical role for extracellular protein disulfide isomerise during thrombus formation in mice. J Clin Invest 118 (2008) 1123-1131
28. Reinhardt C., von Bru{double acute}hl M.L., Manukyan D., Grahl L., Lorenz M., Altmann B., et al. Protein disulfide isomerase acts as an injury response signal that enhances fibrin generation via tissue factor activation. J Clin Invest 118 (2008) 1110-1122
29. Huff T., Otto A.M., Muller C.S., Meier M., and Hannappel E. Thymosin beta4 is released from human blood platelets and attached by factor XIIIa (transglutaminase) to fibrin and collagen. FASEB J 16 (2002) 691-696
30. Cha H.J., Jeong M.J., and Kleinman H.K. Role of thymosin beta4 in tumor metastasis and angiogenesis. J Natl Cancer Inst 95 (2003) 1674-1680
31. Smalley D.M., Root K.E., Ch H., Ross M.M., and Ley K. Proteomic discovery of 21 proteins expressed in human plasma-derived but not platelet-derived microparticles. Thromb Haemost 97 (2007) 67-80
32. Verheul H.M., Jorna A.S., Hoekman K., Broxterman H.J., Gebbink M.F., and Pinedo H.M. Vascular endothelial growth factor-stimulated endothelial cells promote adhesion and activation of platelets. Blood 96 (2000) 4216-4221
33. Pinedo H.M., Verheul H.M.W., D'Amato R.J., and Folkman J. Involvement of platelets in tumor angiogenesis?. Lancet 352 (1998) 1775-1777
34. Jain R.K., Duda D.G., Clark J.W., and Loeffler J.S. Lessons from phase III clinical trials on anti-VEGF therapy for cancer. Nat Clin Pract Oncol 3 (2006) 24-40
35. Vroling L., Yuana Y., Schuurhuis G.J., van Hinsbergh V.W.M., Gundy C., de Haas R., et al. VEGFR2 expressing circulating (progenitor) cell populations in volunteers and cancer patients. Thromb Haemost 98 (2007) 440-450