-
1
-
-
34250214880
-
Myeloid lineage commitment from the hematopoietic stem cell
-
Iwasaki, H. & Akashi, K. Myeloid lineage commitment from the hematopoietic stem cell. Immunity 26, 726-740 (2007).
-
(2007)
Immunity
, vol.26
, pp. 726-740
-
-
Iwasaki, H.1
Akashi, K.2
-
2
-
-
0037071408
-
Transcription factor fusions in acute leukemia: Variations on a theme
-
Scandura, J. M., Boccuni, P., Cammenga, J. & Nimer, S. D. Transcription factor fusions in acute leukemia: variations on a theme. Oncogene 21, 3422-3444 (2002).
-
(2002)
Oncogene
, vol.21
, pp. 3422-3444
-
-
Scandura, J.M.1
Boccuni, P.2
Cammenga, J.3
Nimer, S.D.4
-
3
-
-
0036910536
-
A minigene containing four discrete cis elements recapitulates GATA-1 gene expression in vivo
-
Ohneda, K. et al. A minigene containing four discrete cis elements recapitulates GATA-1 gene expression in vivo. Genes Cells 7, 1243-1254 (2002).
-
(2002)
Genes Cells
, vol.7
, pp. 1243-1254
-
-
Ohneda, K.1
-
4
-
-
0033944801
-
Molecular evolution of the GATA family of transcription factors: Conservation within the DNA-binding domain
-
Lowry, J. A. & Atchley, W. R. Molecular evolution of the GATA family of transcription factors: conservation within the DNA-binding domain. J. Mol. Evol. 50, 103-115 (2000).
-
(2000)
J. Mol. Evol
, vol.50
, pp. 103-115
-
-
Lowry, J.A.1
Atchley, W.R.2
-
5
-
-
0037071383
-
Transcriptional regulation of erythropoiesis: An affair involving multiple partners
-
Cantor, A. B. & Orkin, S. H. Transcriptional regulation of erythropoiesis: an affair involving multiple partners. Oncogene 21, 3368-3376 (2002).
-
(2002)
Oncogene
, vol.21
, pp. 3368-3376
-
-
Cantor, A.B.1
Orkin, S.H.2
-
6
-
-
0036668278
-
The GATA family (vertebrates and invertebrates)
-
Patient, R. K. & McGhee, J. D. The GATA family (vertebrates and invertebrates). Curr. Opin. Genet. Dev. 12, 416-422 (2002).
-
(2002)
Curr. Opin. Genet. Dev
, vol.12
, pp. 416-422
-
-
Patient, R.K.1
McGhee, J.D.2
-
7
-
-
0034671733
-
The zinc finger-containing transcription factors GATA-4, -5, and -6. Ubiquitously expressed regulators of tissue-specific gene expression
-
Molkentin, J. D. The zinc finger-containing transcription factors GATA-4, -5, and -6. Ubiquitously expressed regulators of tissue-specific gene expression. J. Biol. Chem. 275, 38949-38952 (2000).
-
(2000)
J. Biol. Chem
, vol.275
, pp. 38949-38952
-
-
Molkentin, J.D.1
-
8
-
-
0031105607
-
GATA-5: A transcriptional activator expressed in a novel temporally and spatially-restricted pattern during embryonic development
-
Morrisey, E. E., Ip, H. S., Tang, Z., Lu, M. M. & Parmacek, M. S. GATA-5: a transcriptional activator expressed in a novel temporally and spatially-restricted pattern during embryonic development. Dev. Biol. 183, 21-36 (1997).
-
(1997)
Dev. Biol
, vol.183
, pp. 21-36
-
-
Morrisey, E.E.1
Ip, H.S.2
Tang, Z.3
Lu, M.M.4
Parmacek, M.S.5
-
9
-
-
0036604901
-
T helper cell differentiation: On again, off again
-
Grogan, J. L. & Locksley, R. M. T helper cell differentiation: on again, off again. Curr. Opin. Immunol. 14, 366-372 (2002).
-
(2002)
Curr. Opin. Immunol
, vol.14
, pp. 366-372
-
-
Grogan, J.L.1
Locksley, R.M.2
-
10
-
-
12344282813
-
Gene expression regulation and domain function of hematopoietic GATA factors
-
Shimizu, R. & Yamamoto, M. Gene expression regulation and domain function of hematopoietic GATA factors. Semin. Cell Dev. Biol. 16, 129-136 (2005).
-
(2005)
Semin. Cell Dev. Biol
, vol.16
, pp. 129-136
-
-
Shimizu, R.1
Yamamoto, M.2
-
11
-
-
28844484648
-
Generation of embryos directly from embryonic stem cells by tetraploid embryo complementation reveals a role for GATA factors in organogenesis
-
Duncan, S. A. Generation of embryos directly from embryonic stem cells by tetraploid embryo complementation reveals a role for GATA factors in organogenesis. Biochem. Soc. Trans. 33, 1534-1536 (2005).
-
(2005)
Biochem. Soc. Trans
, vol.33
, pp. 1534-1536
-
-
Duncan, S.A.1
-
12
-
-
24344480877
-
Developmental control via GATA factor interplay at chromatin domains
-
Bresnick, E. H., Martowicz, M. L., Pal, S. & Johnson, K. D. Developmental control via GATA factor interplay at chromatin domains. J. Cell Physiol. 205, 1-9 (2005).
-
(2005)
J. Cell Physiol
, vol.205
, pp. 1-9
-
-
Bresnick, E.H.1
Martowicz, M.L.2
Pal, S.3
Johnson, K.D.4
-
13
-
-
0034254262
-
GATA factor transgenes under GATA-1 locus control rescue germ line GATA-1 mutant deficiencies
-
Takahashi, S. et al. GATA factor transgenes under GATA-1 locus control rescue germ line GATA-1 mutant deficiencies. Blood 96, 910-916 (2000).
-
(2000)
Blood
, vol.96
, pp. 910-916
-
-
Takahashi, S.1
-
14
-
-
0035903475
-
In vivo requirements for GATA-1 functional domains during primitive and definitive erythropoiesis
-
This report describes a transgenic complementation rescue assay to clarify in vivo function of the GATA 1NT domain
-
Shimizu, R., Takahashi, S., Ohneda, K., Engel, J. D. & Yamamoto, M. In vivo requirements for GATA-1 functional domains during primitive and definitive erythropoiesis. EMBO J. 20, 5250-5260 (2001). This report describes a transgenic complementation rescue assay to clarify in vivo function of the GATA 1NT domain.
-
(2001)
EMBO J
, vol.20
, pp. 5250-5260
-
-
Shimizu, R.1
Takahashi, S.2
Ohneda, K.3
Engel, J.D.4
Yamamoto, M.5
-
15
-
-
33845932294
-
GATA-4 incompletely substitutes for GATA-1 in promoting both primitive and definitive erythropoiesis in vivo
-
Hosoya-Ohmura, S. et al. GATA-4 incompletely substitutes for GATA-1 in promoting both primitive and definitive erythropoiesis in vivo. J. Biol. Chem. 281, 32820-32830 (2006).
-
(2006)
J. Biol. Chem
, vol.281
, pp. 32820-32830
-
-
Hosoya-Ohmura, S.1
-
16
-
-
0038111018
-
GATA-1-mediated proliferation arrest during erythroid maturation
-
Rylski, M. et al. GATA-1-mediated proliferation arrest during erythroid maturation. Mol. Cell. Biol. 23, 5031-5042 (2003).
-
(2003)
Mol. Cell. Biol
, vol.23
, pp. 5031-5042
-
-
Rylski, M.1
-
17
-
-
0034052854
-
-
Nichols, K. E. et al. Familial dyserythropoietic anaemia and thrombocytopenia due to an inherited mutation in GATA1. Nature Genet. 24, 266-270 (2000). The first report of inherited mutation of GATA1 related to human diseases.
-
Nichols, K. E. et al. Familial dyserythropoietic anaemia and thrombocytopenia due to an inherited mutation in GATA1. Nature Genet. 24, 266-270 (2000). The first report of inherited mutation of GATA1 related to human diseases.
-
-
-
-
18
-
-
0035525746
-
X-linked thrombocytopenia caused by a novel mutation of GATA-1
-
Mehaffey, M. G., Newton, A. L., Gandhi, M. J., Crossley, M. & Drachman, J. G. X-linked thrombocytopenia caused by a novel mutation of GATA-1. Blood 98, 2681-2688 (2001).
-
(2001)
Blood
, vol.98
, pp. 2681-2688
-
-
Mehaffey, M.G.1
Newton, A.L.2
Gandhi, M.J.3
Crossley, M.4
Drachman, J.G.5
-
19
-
-
0035412362
-
Platelet characteristics in patients with X-linked macrothrombocytopenia because of a novel GATA1 mutation
-
Freson, K. et al. Platelet characteristics in patients with X-linked macrothrombocytopenia because of a novel GATA1 mutation. Blood 98, 85-92 (2001).
-
(2001)
Blood
, vol.98
, pp. 85-92
-
-
Freson, K.1
-
20
-
-
0037081819
-
Different substitutions at residue D218 of the X-linked transcription factor GATA1 lead to altered clinical severity of macrothrombocytopenia and anemia and are associated with variable skewed X inactivation
-
Freson, K. et al. Different substitutions at residue D218 of the X-linked transcription factor GATA1 lead to altered clinical severity of macrothrombocytopenia and anemia and are associated with variable skewed X inactivation. Hum. Mol. Genet. 11, 147-152 (2002).
-
(2002)
Hum. Mol. Genet
, vol.11
, pp. 147-152
-
-
Freson, K.1
-
21
-
-
0037105495
-
X-linked thrombocytopenia with thalassemia from a mutation in the amino finger of GATA-1 affecting DNA binding rather than FOG-1 interaction
-
Yu, C. et al. X-linked thrombocytopenia with thalassemia from a mutation in the amino finger of GATA-1 affecting DNA binding rather than FOG-1 interaction. Blood 100, 2040-2045 (2002).
-
(2002)
Blood
, vol.100
, pp. 2040-2045
-
-
Yu, C.1
-
22
-
-
33947223723
-
Congenital erythropoietic porphyria due to a mutation in GATA-1: The first trans-acting mutation causative for a human porphyria
-
Phillips, J. D., Steensma, D. P., Pulsipher, M. A., Spangrude, G. J. & Kushner, J. P. Congenital erythropoietic porphyria due to a mutation in GATA-1: the first trans-acting mutation causative for a human porphyria. Blood 109, 2618-2621 (2006).
-
(2006)
Blood
, vol.109
, pp. 2618-2621
-
-
Phillips, J.D.1
Steensma, D.P.2
Pulsipher, M.A.3
Spangrude, G.J.4
Kushner, J.P.5
-
23
-
-
0027395052
-
Erythroid transcription factor GATA-1 is abundantly transcribed in mouse testis
-
Ito, E. et al. Erythroid transcription factor GATA-1 is abundantly transcribed in mouse testis. Nature 362, 466-468 (1993).
-
(1993)
Nature
, vol.362
, pp. 466-468
-
-
Ito, E.1
-
24
-
-
0028301477
-
Developmental stage- and spermatogenic cycle-specific expression of transcription factor GATA-1 in mouse Sertoli cells
-
Yomogida, K. et al. Developmental stage- and spermatogenic cycle-specific expression of transcription factor GATA-1 in mouse Sertoli cells. Development 120, 1759-1766 (1994).
-
(1994)
Development
, vol.120
, pp. 1759-1766
-
-
Yomogida, K.1
-
25
-
-
0030979027
-
-
Takahashi, S. et al. Arrest in primitive erythroid cell development caused by promoter- specific disruption of the GATA-1 gene. J. Biol. Chem. 272, 12611-12615 (1997). This paper describes the generation of the first Gata1-knockdown ( Gata1.05) mouse line.
-
Takahashi, S. et al. Arrest in primitive erythroid cell development caused by promoter- specific disruption of the GATA-1 gene. J. Biol. Chem. 272, 12611-12615 (1997). This paper describes the generation of the first Gata1-knockdown ( Gata1.05) mouse line.
-
-
-
-
26
-
-
0029926485
-
Arrested development of embryonic red cell precursors in mouse embryos lacking transcription factor GATA-1
-
Fujiwara, Y., Browne, C. P., Cunniff, K., Goff, S. C. & Orkin, S. H. Arrested development of embryonic red cell precursors in mouse embryos lacking transcription factor GATA-1. Proc. Natl Acad. Sci. USA 93, 12355-12358 (1996).
-
(1996)
Proc. Natl Acad. Sci. USA
, vol.93
, pp. 12355-12358
-
-
Fujiwara, Y.1
Browne, C.P.2
Cunniff, K.3
Goff, S.C.4
Orkin, S.H.5
-
27
-
-
7144223296
-
Gene action in the X-chromosome of the mouse (Mus musculus L.)
-
Lyon, M. F. Gene action in the X-chromosome of the mouse (Mus musculus L.). Nature 190, 372-373 (1961).
-
(1961)
Nature
, vol.190
, pp. 372-373
-
-
Lyon, M.F.1
-
28
-
-
10044274335
-
-
Shimizu, R. et al. Leukemogenesis caused by incapacitated GATA-1 function. Mol. Cell. Biol. 24, 10814-10825 (2004). This paper demonstrates that quantitative reduction of the Gata1 expression gives rise to perturbation in erythropoiesis, leading to leukemogenesis.
-
Shimizu, R. et al. Leukemogenesis caused by incapacitated GATA-1 function. Mol. Cell. Biol. 24, 10814-10825 (2004). This paper demonstrates that quantitative reduction of the Gata1 expression gives rise to perturbation in erythropoiesis, leading to leukemogenesis.
-
-
-
-
29
-
-
0031001561
-
GATA-1 transcription is controlled by distinct regulatory mechanisms during primitive and definitive erythropoiesis
-
Onodera, K. et al. GATA-1 transcription is controlled by distinct regulatory mechanisms during primitive and definitive erythropoiesis. Proc. Natl Acad. Sci. USA 94, 4487-4492 (1997).
-
(1997)
Proc. Natl Acad. Sci. USA
, vol.94
, pp. 4487-4492
-
-
Onodera, K.1
-
30
-
-
0033983960
-
A GATA box in the GATA-1 gene hematopoietic enhancer is a critical element in the network of GATA factors and sites that regulate this gene
-
Nishimura, S. et al. A GATA box in the GATA-1 gene hematopoietic enhancer is a critical element in the network of GATA factors and sites that regulate this gene. Mol. Cell. Biol. 20, 713-723 (2000).
-
(2000)
Mol. Cell. Biol
, vol.20
, pp. 713-723
-
-
Nishimura, S.1
-
31
-
-
38449104294
-
Regulation of GATA1 gene expression
-
Kobayashi, M. & Yamamoto, M. Regulation of GATA1 gene expression. J. Biochem. 142, 1-10 (2007).
-
(2007)
J. Biochem
, vol.142
, pp. 1-10
-
-
Kobayashi, M.1
Yamamoto, M.2
-
32
-
-
0242411607
-
Identification and characterization of 2 types of erythroid progenitors that express GATA-1 at distinct levels
-
Suzuki, N. et al. Identification and characterization of 2 types of erythroid progenitors that express GATA-1 at distinct levels. Blood 102, 3575-3583 (2003).
-
(2003)
Blood
, vol.102
, pp. 3575-3583
-
-
Suzuki, N.1
-
33
-
-
0029918597
-
Disruption of the Cbfa2 gene causes necrosis and hemorrhaging in the central nervous system and blocks definitive hematopoiesis
-
Wang, Q. et al. Disruption of the Cbfa2 gene causes necrosis and hemorrhaging in the central nervous system and blocks definitive hematopoiesis. Proc. Natl Acad. Sci. USA 93, 3444-3449 (1996).
-
(1996)
Proc. Natl Acad. Sci. USA
, vol.93
, pp. 3444-3449
-
-
Wang, Q.1
-
34
-
-
0032830638
-
Haploinsufficiency of CBFA2 causes familial thrombocytopenia with propensity to develop acute myelogenous leukaemia
-
Song, W. J. et al. Haploinsufficiency of CBFA2 causes familial thrombocytopenia with propensity to develop acute myelogenous leukaemia. Nature Genet. 23, 166-175 (1999).
-
(1999)
Nature Genet
, vol.23
, pp. 166-175
-
-
Song, W.J.1
-
35
-
-
0030061554
-
AML1, the target of multiple chromosomal translocations in human leukemia, is essential for normal fetal liver hematopoiesis
-
Okuda, T., van Deursen, J., Hiebert, S. W., Grosveld, G. & Downing, J. R. AML1, the target of multiple chromosomal translocations in human leukemia, is essential for normal fetal liver hematopoiesis. Cell 84, 321-330 (1996).
-
(1996)
Cell
, vol.84
, pp. 321-330
-
-
Okuda, T.1
van Deursen, J.2
Hiebert, S.W.3
Grosveld, G.4
Downing, J.R.5
-
36
-
-
37349112219
-
Runx1 protects hematopoietic stem/progenitor cells from oncogenic insult
-
Motoda, L. et al. Runx1 protects hematopoietic stem/progenitor cells from oncogenic insult. Stem Cells 25, 2976-2986 (2007).
-
(2007)
Stem Cells
, vol.25
, pp. 2976-2986
-
-
Motoda, L.1
-
37
-
-
0032962544
-
The key role of PU.1/SPI-1 in B cells, myeloid cells and macrophages
-
Lloberas, J., Soler, C. & Celada, A. The key role of PU.1/SPI-1 in B cells, myeloid cells and macrophages. Immunol. Today 20, 184-189 (1999).
-
(1999)
Immunol. Today
, vol.20
, pp. 184-189
-
-
Lloberas, J.1
Soler, C.2
Celada, A.3
-
38
-
-
0028136726
-
Requirement of transcription factor PU.1 in the development of multiple hematopoietic lineages
-
Scott, E. W., Simon, M. C., Anastasi, J. & Singh, H. Requirement of transcription factor PU.1 in the development of multiple hematopoietic lineages. Science 265, 1573-1577 (1994).
-
(1994)
Science
, vol.265
, pp. 1573-1577
-
-
Scott, E.W.1
Simon, M.C.2
Anastasi, J.3
Singh, H.4
-
39
-
-
18644373047
-
PU.1 regulates the commitment of adult hematopoietic progenitors and restricts granulopoiesis
-
Dakic, A. et al. PU.1 regulates the commitment of adult hematopoietic progenitors and restricts granulopoiesis. J. Exp. Med. 201, 1487-1502 (2005).
-
(2005)
J. Exp. Med
, vol.201
, pp. 1487-1502
-
-
Dakic, A.1
-
40
-
-
34848850741
-
A distal single nucleotide polymorphism alters long-range regulation of the PU.1 gene in acute myeloid leukemia
-
Steidl, U. et al. A distal single nucleotide polymorphism alters long-range regulation of the PU.1 gene in acute myeloid leukemia. J. Clin. Invest. 117, 2611-2620 (2007).
-
(2007)
J. Clin. Invest
, vol.117
, pp. 2611-2620
-
-
Steidl, U.1
-
41
-
-
2642519463
-
Acute myeloid leukemia induced by graded reduction of a lineage-specific transcription factor, PU.1
-
This paper and references 28 and 34 describe the leukaemogenesis that is related to the attenuated expression of key transcription factors in human and mouse
-
Rosenbauer, F. et al. Acute myeloid leukemia induced by graded reduction of a lineage-specific transcription factor, PU.1. Nature Genet. 36, 624-630 (2004). This paper and references 28 and 34 describe the leukaemogenesis that is related to the attenuated expression of key transcription factors in human and mouse.
-
(2004)
Nature Genet
, vol.36
, pp. 624-630
-
-
Rosenbauer, F.1
-
42
-
-
31944450531
-
Inactivation of PU.1 in adult mice leads to the development of myeloid leukemia
-
Metcalf, D. et al. Inactivation of PU.1 in adult mice leads to the development of myeloid leukemia. Proc. Natl Acad. Sci. USA 103, 1486-1491 (2006).
-
(2006)
Proc. Natl Acad. Sci. USA
, vol.103
, pp. 1486-1491
-
-
Metcalf, D.1
-
43
-
-
0030029385
-
In vitro development of primitive and definitive erythrocytes from different precursors
-
Nakano, T., Kodama, H. & Honjo, T. In vitro development of primitive and definitive erythrocytes from different precursors. Science 272, 722-724 (1996).
-
(1996)
Science
, vol.272
, pp. 722-724
-
-
Nakano, T.1
Kodama, H.2
Honjo, T.3
-
44
-
-
20444485344
-
-
Pan, X. et al. Graded levels of GATA-1 expression modulate survival, proliferation and differentiation of erythroid progenitors. J. Biol. Chem. 280, 22385-22394 (2005). An in vitro ES cell differentiation system was used to prove integrated function of GATA1.
-
Pan, X. et al. Graded levels of GATA-1 expression modulate survival, proliferation and differentiation of erythroid progenitors. J. Biol. Chem. 280, 22385-22394 (2005). An in vitro ES cell differentiation system was used to prove integrated function of GATA1.
-
-
-
-
45
-
-
0032402115
-
GATA-1 regulates growth and differentiation of definitive erythroid lineage cells during in vitro ES cell differentiation
-
Suwabe, N., Takahashi, S., Nakano, T. & Yamamoto, M. GATA-1 regulates growth and differentiation of definitive erythroid lineage cells during in vitro ES cell differentiation. Blood 92, 4108-4118 (1998).
-
(1998)
Blood
, vol.92
, pp. 4108-4118
-
-
Suwabe, N.1
Takahashi, S.2
Nakano, T.3
Yamamoto, M.4
-
46
-
-
0034709565
-
Transcription factor GATA-2 gene is located near 3q21 breakpoints in myeloid leukemia
-
Wieser, R. et al. Transcription factor GATA-2 gene is located near 3q21 breakpoints in myeloid leukemia. Biochem. Biophys. Res. Commun. 273, 239-245 (2000).
-
(2000)
Biochem. Biophys. Res. Commun
, vol.273
, pp. 239-245
-
-
Wieser, R.1
-
47
-
-
41149099547
-
-
Wechsler, J. et al. Acquired mutations in GATA1 in the megakaryoblastic leukemia of Down syndrome. Nature Genet. 12, 1-5 (2002). The first paper demonstrating the linkage between somatic mutations in the GATA1 gene and DS-AMKL.
-
Wechsler, J. et al. Acquired mutations in GATA1 in the megakaryoblastic leukemia of Down syndrome. Nature Genet. 12, 1-5 (2002). The first paper demonstrating the linkage between somatic mutations in the GATA1 gene and DS-AMKL.
-
-
-
-
48
-
-
0242720661
-
Mutations in GATA1 in both transient myeloproliferative disorder and acute megakaryoblastic leukemia of Down syndrome
-
Greene, M. E. et al. Mutations in GATA1 in both transient myeloproliferative disorder and acute megakaryoblastic leukemia of Down syndrome. Blood Cells Mol. Dis. 31, 351-356 (2003).
-
(2003)
Blood Cells Mol. Dis
, vol.31
, pp. 351-356
-
-
Greene, M.E.1
-
49
-
-
0042243593
-
Mutations in exon 2 of GATA1 are early events in megakaryocytic malignancies associated with trisomy 21
-
Rainis, L. et al. Mutations in exon 2 of GATA1 are early events in megakaryocytic malignancies associated with trisomy 21. Blood 102, 981-986 (2003).
-
(2003)
Blood
, vol.102
, pp. 981-986
-
-
Rainis, L.1
-
50
-
-
85117737444
-
-
Xu, G. et al. Frequent mutations in the GATA-1 gene in the transient myeloproliferative disorder of Down syndrome. Blood 102, 2960-2968 (2003). References 48-50 show that somatic mutations of GATA1, which result in the production of short form GATA1, are related to TMD and DS-AMKL.
-
Xu, G. et al. Frequent mutations in the GATA-1 gene in the transient myeloproliferative disorder of Down syndrome. Blood 102, 2960-2968 (2003). References 48-50 show that somatic mutations of GATA1, which result in the production of short form GATA1, are related to TMD and DS-AMKL.
-
-
-
-
51
-
-
0346966816
-
Fetal origin of the GATA1 mutation in identical twins with transient myeloproliferative disorder and acute megakaryoblastic leukemia accompanying Down syndrome
-
Shimada, A. et al. Fetal origin of the GATA1 mutation in identical twins with transient myeloproliferative disorder and acute megakaryoblastic leukemia accompanying Down syndrome. Blood 103, 366 (2004).
-
(2004)
Blood
, vol.103
, pp. 366
-
-
Shimada, A.1
-
52
-
-
0037433652
-
Down's syndrome
-
Roizen, N. J. & Patterson, D. Down's syndrome. Lancet 361, 1281-1289 (2003).
-
(2003)
Lancet
, vol.361
, pp. 1281-1289
-
-
Roizen, N.J.1
Patterson, D.2
-
53
-
-
0037355255
-
Transient leukaemia - a benign form of leukaemia in newborn infants with trisomy 21
-
Zipursky, A. Transient leukaemia - a benign form of leukaemia in newborn infants with trisomy 21. Br. J. Haematol. 120, 930-938 (2003).
-
(2003)
Br. J. Haematol
, vol.120
, pp. 930-938
-
-
Zipursky, A.1
-
54
-
-
11144242549
-
Origins of leukaemia in children with Down syndrome
-
Hitzler, J. K. & Zipursky, A. Origins of leukaemia in children with Down syndrome. Nature Rev. Cancer 5, 11-20 (2005).
-
(2005)
Nature Rev. Cancer
, vol.5
, pp. 11-20
-
-
Hitzler, J.K.1
Zipursky, A.2
-
55
-
-
1842422317
-
The GATA1 mutation in an adult patient with acute megakaryoblastic leukemia not accompanying Down syndrome
-
Harigae, H. et al. The GATA1 mutation in an adult patient with acute megakaryoblastic leukemia not accompanying Down syndrome. Blood 103, 3242-3243 (2004).
-
(2004)
Blood
, vol.103
, pp. 3242-3243
-
-
Harigae, H.1
-
56
-
-
85117737874
-
-
Ahmed, M. et al. Natural history of GATA1 mutations in Down syndrome. Blood 103, 2480-2489 (2004). Sequential clinical study focused on the relationship between GATA1 mutation and history of TMD and AMKL in DS children.
-
Ahmed, M. et al. Natural history of GATA1 mutations in Down syndrome. Blood 103, 2480-2489 (2004). Sequential clinical study focused on the relationship between GATA1 mutation and history of TMD and AMKL in DS children.
-
-
-
-
57
-
-
0038142350
-
GATA1 mutations in transient leukemia and acute megakaryoblastic leukemia of Down syndrome
-
Hitzler, J. K., Cheung, J., Li, Y., Scherer, S. W. & Zipursky, A. GATA1 mutations in transient leukemia and acute megakaryoblastic leukemia of Down syndrome. Blood 101, 4301-4304 (2003).
-
(2003)
Blood
, vol.101
, pp. 4301-4304
-
-
Hitzler, J.K.1
Cheung, J.2
Li, Y.3
Scherer, S.W.4
Zipursky, A.5
-
58
-
-
33749577270
-
Development of acute megakaryoblastic leukemia from a minor clone in a Down syndrome patient with clinically overt transient myeloproliferative disorder
-
Xu, G. et al. Development of acute megakaryoblastic leukemia from a minor clone in a Down syndrome patient with clinically overt transient myeloproliferative disorder. J. Pediatr. Hematol. Oncol. 28, 696-698 (2006).
-
(2006)
J. Pediatr. Hematol. Oncol
, vol.28
, pp. 696-698
-
-
Xu, G.1
-
59
-
-
0036151278
-
Acute megakaryoblastic leukemia after transient myeloproliferative disorder with clonal karyotype evolution in a phenotypically normal neonate
-
Polski, J. M. et al. Acute megakaryoblastic leukemia after transient myeloproliferative disorder with clonal karyotype evolution in a phenotypically normal neonate. J. Pediatr. Hematol. Oncol. 24, 50-54 (2002).
-
(2002)
J. Pediatr. Hematol. Oncol
, vol.24
, pp. 50-54
-
-
Polski, J.M.1
-
60
-
-
33646842013
-
Risk for leukemia in infants without Down syndrome who have transient myeloproliferative disorder
-
Cushing, T. et al. Risk for leukemia in infants without Down syndrome who have transient myeloproliferative disorder. J. Pediatr. 148, 687-689 (2006).
-
(2006)
J. Pediatr
, vol.148
, pp. 687-689
-
-
Cushing, T.1
-
61
-
-
35349004269
-
Transient myeloproliferative disorder in a neonate without Down syndrome
-
Adam, M. et al. Transient myeloproliferative disorder in a neonate without Down syndrome. Ann. Biol. Clin. 65, 569-573 (2007).
-
(2007)
Ann. Biol. Clin
, vol.65
, pp. 569-573
-
-
Adam, M.1
-
62
-
-
0034837339
-
Murine models for Down syndrome
-
Dierssen, M. et al. Murine models for Down syndrome. Physiol. Behav. 73, 859-871 (2001).
-
(2001)
Physiol. Behav
, vol.73
, pp. 859-871
-
-
Dierssen, M.1
-
63
-
-
5044234361
-
Chromosome 21 and Down syndrome: From genomics to pathophysiology
-
Antonarakis, S. E., Lyle, R., Dermitzakis, E. T., Reymond, A. & Deutsch, S. Chromosome 21 and Down syndrome: from genomics to pathophysiology. Nature Rev. Genet. 5, 725-738 (2004).
-
(2004)
Nature Rev. Genet
, vol.5
, pp. 725-738
-
-
Antonarakis, S.E.1
Lyle, R.2
Dermitzakis, E.T.3
Reymond, A.4
Deutsch, S.5
-
64
-
-
0027719985
-
Segmental trisomy as a mouse model for Down syndrome
-
Davisson, M. T. et al. Segmental trisomy as a mouse model for Down syndrome. Prog. Clin. Biol. Res. 384, 117-133 (1993).
-
(1993)
Prog. Clin. Biol. Res
, vol.384
, pp. 117-133
-
-
Davisson, M.T.1
-
65
-
-
0036467052
-
Craniofacial phenotypes in segmentally trisomic mouse models for Down syndrome
-
Richtsmeier, J. T., Zumwalt, A., Carlson, E. J., Epstein, C. J. & Reeves, R. H. Craniofacial phenotypes in segmentally trisomic mouse models for Down syndrome. Am. J. Med. Genet. 107, 317-324 (2002).
-
(2002)
Am. J. Med. Genet
, vol.107
, pp. 317-324
-
-
Richtsmeier, J.T.1
Zumwalt, A.2
Carlson, E.J.3
Epstein, C.J.4
Reeves, R.H.5
-
66
-
-
0029114706
-
A mouse model for Down syndrome exhibits learning and behaviour deficits
-
Reeves, R. H. et al. A mouse model for Down syndrome exhibits learning and behaviour deficits. Nature Genet. 11, 177-184 (1995).
-
(1995)
Nature Genet
, vol.11
, pp. 177-184
-
-
Reeves, R.H.1
-
67
-
-
33749576059
-
Postnatal lethality and cardiac anomalies in the Ts65Dn Down syndrome mouse model
-
Moore, C. S. Postnatal lethality and cardiac anomalies in the Ts65Dn Down syndrome mouse model. Mamm. Genome 17, 1005-1012 (2006).
-
(2006)
Mamm. Genome
, vol.17
, pp. 1005-1012
-
-
Moore, C.S.1
-
68
-
-
38349119730
-
Highly penetrant myeloproliferative disease in the Ts65Dn mouse model of Down syndrome
-
Kirsammer, G. et al. Highly penetrant myeloproliferative disease in the Ts65Dn mouse model of Down syndrome. Blood 111, 767-775 (2008).
-
(2008)
Blood
, vol.111
, pp. 767-775
-
-
Kirsammer, G.1
-
69
-
-
33845990286
-
Hematological abnormalities during the first week of life among neonates with Down syndrome: Data from a multihospital healthcare system
-
Henry, E., Walker, D., Wiedmeier, S. E. & Christensen, R. D. Hematological abnormalities during the first week of life among neonates with Down syndrome: data from a multihospital healthcare system. Am. J. Med. Genet. A 143, 42-50 (2007).
-
(2007)
Am. J. Med. Genet. A
, vol.143
, pp. 42-50
-
-
Henry, E.1
Walker, D.2
Wiedmeier, S.E.3
Christensen, R.D.4
-
70
-
-
33751544732
-
Hematopoietic progenitor cell deficiency in fetuses and children affected by Down's syndrome
-
Holmes, D. K. et al. Hematopoietic progenitor cell deficiency in fetuses and children affected by Down's syndrome. Exp. Hematol. 34, 1611-1615 (2006).
-
(2006)
Exp. Hematol
, vol.34
, pp. 1611-1615
-
-
Holmes, D.K.1
-
71
-
-
20144387545
-
Transgenic expression of Bach1 transcription factor results in megakaryocytic impairment
-
Toki, T. et al. Transgenic expression of Bach1 transcription factor results in megakaryocytic impairment. Blood 105, 3100-3108 (2005).
-
(2005)
Blood
, vol.105
, pp. 3100-3108
-
-
Toki, T.1
-
72
-
-
33846245565
-
+ hemangioblastic cells in the mouse embryo
-
+ hemangioblastic cells in the mouse embryo. EMBO J. 26, 184-196 (2007).
-
(2007)
EMBO J
, vol.26
, pp. 184-196
-
-
Yokomizo, T.1
-
73
-
-
25444497962
-
GATA1-mediated megakaryocyte differentiation and growth control can be uncoupled and mapped to different domains in GATA1
-
Kuhl, C. et al. GATA1-mediated megakaryocyte differentiation and growth control can be uncoupled and mapped to different domains in GATA1. Mol. Cell. Biol. 25, 8592-8606 (2005).
-
(2005)
Mol. Cell. Biol
, vol.25
, pp. 8592-8606
-
-
Kuhl, C.1
-
74
-
-
23044499360
-
Differential requirements for the activation domain and FOG-interaction surface of GATA-1 in megakaryocyte gene expression and development
-
Muntean, A. G. & Crispino, J. D. Differential requirements for the activation domain and FOG-interaction surface of GATA-1 in megakaryocyte gene expression and development. Blood 106, 1223-1231 (2005).
-
(2005)
Blood
, vol.106
, pp. 1223-1231
-
-
Muntean, A.G.1
Crispino, J.D.2
-
75
-
-
0037047059
-
GATA-factor dependence of the multitype zinc-finger protein FOG-1 for its essential role in megakaryopoiesis
-
Chang, A. N. et al. GATA-factor dependence of the multitype zinc-finger protein FOG-1 for its essential role in megakaryopoiesis. Proc. Natl Acad. Sci. USA 99, 9237-9242 (2002).
-
(2002)
Proc. Natl Acad. Sci. USA
, vol.99
, pp. 9237-9242
-
-
Chang, A.N.1
-
76
-
-
1642366235
-
Transgenic rescue of GATA-1-deficient mice with GATA-1 lacking a FOG-1 association site phenocopies patients with X-linked thrombocytopenia
-
Shimizu, R., Ohneda, K., Engel, J. D., Trainor, C. D. & Yamamoto, M. Transgenic rescue of GATA-1-deficient mice with GATA-1 lacking a FOG-1 association site phenocopies patients with X-linked thrombocytopenia. Blood 103, 2560-2567 (2004).
-
(2004)
Blood
, vol.103
, pp. 2560-2567
-
-
Shimizu, R.1
Ohneda, K.2
Engel, J.D.3
Trainor, C.D.4
Yamamoto, M.5
-
78
-
-
20044381309
-
Developmental stage-selective effect of somatically mutated leukemogenic transcription factor GATA1
-
Li, Z. et al. Developmental stage-selective effect of somatically mutated leukemogenic transcription factor GATA1. Nature Genet. 37, 613-619 (2005).
-
(2005)
Nature Genet
, vol.37
, pp. 613-619
-
-
Li, Z.1
-
79
-
-
33845336152
-
The balance between heritable and environmental aetiology of human disease
-
Hemminki, K., Lorenzo Bermejo, J. & Forsti, A. The balance between heritable and environmental aetiology of human disease. Nature Rev. Genet. 7, 958-965 (2006).
-
(2006)
Nature Rev. Genet
, vol.7
, pp. 958-965
-
-
Hemminki, K.1
Lorenzo Bermejo, J.2
Forsti, A.3
-
80
-
-
0025129925
-
Activity and tissue-specific expression of the transcription factor NF-E1 multigene family
-
Yamamoto, M. et al. Activity and tissue-specific expression of the transcription factor NF-E1 multigene family. Genes Dev. 4, 1650-1662 (1990).
-
(1990)
Genes Dev
, vol.4
, pp. 1650-1662
-
-
Yamamoto, M.1
-
81
-
-
33144489359
-
Combinatorial Gata2 and Sca1 expression defines hematopoietic stem cells in the bone marrow niche
-
Suzuki, N. et al. Combinatorial Gata2 and Sca1 expression defines hematopoietic stem cells in the bone marrow niche. Proc. Natl Acad. Sci. USA 103, 2202-2207 (2006).
-
(2006)
Proc. Natl Acad. Sci. USA
, vol.103
, pp. 2202-2207
-
-
Suzuki, N.1
-
82
-
-
34249037850
-
A Gata2 intronic enhancer confers its pan-endothelia-specific regulation
-
Khandekar, M. et al. A Gata2 intronic enhancer confers its pan-endothelia-specific regulation. Development 139, 1703-1712 (2007).
-
(2007)
Development
, vol.139
, pp. 1703-1712
-
-
Khandekar, M.1
-
83
-
-
0029087975
-
Targeted disruption of the GATA3 gene causes severe abnormalities in the nervous system and in fetal liver haematopoiesis
-
Pandolfi, P. P. et al. Targeted disruption of the GATA3 gene causes severe abnormalities in the nervous system and in fetal liver haematopoiesis. Nature Genet. 11, 40-44 (1995).
-
(1995)
Nature Genet
, vol.11
, pp. 40-44
-
-
Pandolfi, P.P.1
-
85
-
-
0034623079
-
GATA zinc finger interactions modulate DNA binding and transactivation
-
Trainor, C. D., Ghirlando, R. & Simpson, M. A. GATA zinc finger interactions modulate DNA binding and transactivation. J. Biol. Chem. 275, 28157-28166 (2000).
-
(2000)
J. Biol. Chem
, vol.275
, pp. 28157-28166
-
-
Trainor, C.D.1
Ghirlando, R.2
Simpson, M.A.3
-
86
-
-
0029863093
-
A palindromic regulatory site within vertebrate GATA-1 promoters requires both zinc fingers of the GATA-1 DNA-binding domain for high-affinity interaction
-
Trainor, C. D. et al. A palindromic regulatory site within vertebrate GATA-1 promoters requires both zinc fingers of the GATA-1 DNA-binding domain for high-affinity interaction. Mol. Cell. Biol. 16, 2238-2247 (1996).
-
(1996)
Mol. Cell. Biol
, vol.16
, pp. 2238-2247
-
-
Trainor, C.D.1
-
87
-
-
0041806587
-
GATA-1-dependent transcriptional repression of GATA-2 via disruption of positive autoregulation and domain-wide chromatin remodeling
-
Grass, J. A. et al. GATA-1-dependent transcriptional repression of GATA-2 via disruption of positive autoregulation and domain-wide chromatin remodeling. Proc. Natl Acad. Sci. USA 100, 8811-8816 (2003).
-
(2003)
Proc. Natl Acad. Sci. USA
, vol.100
, pp. 8811-8816
-
-
Grass, J.A.1
-
88
-
-
23344452957
-
GATA motifs regulate early hematopoietic lineage-specific expression of Gata2 gene
-
Kobayashi-Osaki, M. et al. GATA motifs regulate early hematopoietic lineage-specific expression of Gata2 gene. Mol. Cell. Biol. 25, 7005-7020 (2005).
-
(2005)
Mol. Cell. Biol
, vol.25
, pp. 7005-7020
-
-
Kobayashi-Osaki, M.1
-
89
-
-
0035760889
-
-/- mice due to decreased survival of early erythroblasts
-
-/- mice due to decreased survival of early erythroblasts. Blood 98, 3261-3273 (2001).
-
(2001)
Blood
, vol.98
, pp. 3261-3273
-
-
Socolovsky, M.1
-
90
-
-
0033724650
-
Mechanisms of differential transferrin receptor expression in normal hematopoiesis
-
Sposi, N. M. et al. Mechanisms of differential transferrin receptor expression in normal hematopoiesis. Eur. J. Biochem. 267, 6762-6774 (2000).
-
(2000)
Eur. J. Biochem
, vol.267
, pp. 6762-6774
-
-
Sposi, N.M.1
-
91
-
-
0023158748
-
Flow cytometric analysis of human bone marrow: I. Normal erythroid development
-
Loken, M. R., Shah, V. O., Dattilio, K. L. & Civin, C. I. Flow cytometric analysis of human bone marrow: I. Normal erythroid development. Blood 69, 255-263 (1987).
-
(1987)
Blood
, vol.69
, pp. 255-263
-
-
Loken, M.R.1
Shah, V.O.2
Dattilio, K.L.3
Civin, C.I.4
-
92
-
-
0942263632
-
The monoclonal antibody TER-119 recognizes a molecule associated with glycophorin A and specifically marks the late stages of murine erythroid lineage
-
Kina, T. et al. The monoclonal antibody TER-119 recognizes a molecule associated with glycophorin A and specifically marks the late stages of murine erythroid lineage. Br. J. Haematol. 109, 280-287 (2000).
-
(2000)
Br. J. Haematol
, vol.109
, pp. 280-287
-
-
Kina, T.1
-
93
-
-
0343235650
-
Conserved structure, regulatory elements, and transcriptional regulation from the GATA-1 gene testis promoter
-
Onodera, K. et al. Conserved structure, regulatory elements, and transcriptional regulation from the GATA-1 gene testis promoter. J. Biochem. 121, 251-263 (1997).
-
(1997)
J. Biochem
, vol.121
, pp. 251-263
-
-
Onodera, K.1
|